Conserved Protein Domain Family
Jnk-SapK_ap_N

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pfam09744: Jnk-SapK_ap_N 
JNK_SAPK-associated protein-1
This is the N-terminal 200 residues of a set of proteins conserved from yeasts to humans. Most of the proteins in this entry have an RhoGEF pfam00621 domain at their C-terminal end.
Statistics
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PSSM-Id: 462875
Aligned: 37 rows
Threshold Bit Score: 116.561
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CDS43653       46 VQAIAHRFNAEFEAVLAAgeadsgARAAIVQRLLPTVVAVLEQLDEFYKDHAAYKAEVVQLREETTSLFSQLTKEKSARR 125 
Q29EP6         42 VQQLAGSIYQEFERMINR------YDEDVVKNLMPLLVNVLECLDASYRINQEQDVELELLREDNEQLVTQYEREKSARK 115  Drosophila ps...
EFN78716       21 VQSLAGSIYQEFEKMIAR------YDEDVVKDLMPLLVNVLECLDISYTENQEREVELELLREDNEQLVTQYEREKQLRK 94  
XP_013131630   23 VSGLANSIYREFERLIGK------YDEDVVKELMPLVVAVLENLDSVFAENQEHEVELELLKEDNEQLITQYEREKALRK 96  
5_pfamImport    1 VSGLANSIYREFERLIGK------YDEDVVKELMPLVVAVLENLDSVFAENQEHEVELELLKEDNEQLITQYEREKALRK 74  
KQK73481      109 VSGLAGSIYREFERLIGR------YDEEVVAELMPLVVAVLENLDSVCAHSQETSVELELLRXDNEQLLTQYEREKALRK 182 
BAB15727       39 VSGLAGSIYREFERLIHC------YDEEVVKELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALRR 112 
EKC20447       22 VSSLATNIYKEFERMIKK------YDEDVVKELMPLIVALLEGLDQSLSDKQEADVELELLRDDNEQLLTQYEREKQLRK 95  
XP_025196361   21 VQSLAGSIYQEFEKMISK------YDEEVVKNLMPLVVNVLECLDLSHTENQEHEVEVELLREDNEQLVTQYEREKQLRK 94  
EEC20519       27 VQTLAGNIYQEFQRMIEK------YDEDVVKDLMPLVVNVLESLDLACMENQEHEVELELLREDNEQLVTQYEREKQLRK 100 
CDS43653      126 DTEDLLMRMEDQFESERKILNEALAQNETQIRRLEiks----knvEEQLARMEQKEQESLKENSKLHERINELLRSHAEL 201 
Q29EP6        116 QSEQKLLEAEDLAEQENKELATRLESVESIVRMLElkh----knsLEHASRLEERETDLKKEYNKLHERYTELFKNHVDY 191  Drosophila ps...
EFN78716       95 ASDQKLLELEDVSEDERKELLSKIDSLESIVRMLElkt----knsHDHVGRLEEKEAELKREYSRLHDRYTELFKTHVDY 170 
XP_013131630   97 HAEEKFIEFEDTHEQEKKDLQSHVDRMESHSRQLElki----knyADQIGRLEEREMDLKKEYNSLHQRHTEMIHNYMEH 172 
5_pfamImport   75 QAEETFGLYEITSEQDH--LSSFLTGTDTRTSELSpfsilkssgfATKLGRLEERELELKKEYNSLHQRHSEKIPNYMGH 152 
KQK73481      183 QAEEKFIEFEDSQEQEKKELQTRVEALESQTRQLElka----knyADQISRLEEREAELKKEYNALHSRHTEMIHNYMEH 258 
BAB15727      113 QAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLElka----knyADQISRLEERESEMKKEYNALHQRHTEMIQTYVEH 188 
EKC20447       96 GTEQKYLEMEDAVEGEKKSMQDKLESLESVVRMLElkv----knsADHVSRMEEKEVDLKKEYTKLHERYTELFRTHMDY 171 
XP_025196361   95 SAEQKLLEMEDYIEDEKKDYQSKIESLESIVRMLElka----knaSDHVYRLEEKEQDMKQEYTKLHERYTELFKTHMDH 170 
EEC20519      101 ASEQKLLEVEYTVDDDRRDLEGKVEGLESVIRMLElks----kntSDHANRLEEKESEMKKEFSKLHERYTELFKTHMDY 176 
CDS43653      202 NDSLKQ 207 
Q29EP6        192 MERTKM 197  Drosophila pseudoobscura pseudoobscura
EFN78716      171 MERTKM 176 
XP_013131630  173 VERIKM 178 
5_pfamImport  153 VGRIKM 158 
KQK73481      259 LERTKL 264 
BAB15727      189 IERSKM 194 
EKC20447      172 MERTKI 177 
XP_025196361  171 IERTKI 176 
EEC20519      177 IERTKI 182 
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