6HG4


Conserved Protein Domain Family
IL17_R_N

?
pfam15037: IL17_R_N 
Interleukin-17 receptor extracellular region
This domain is found at the N-terminus (extracellular region) of interleukin-17 receptor C and Interleukin-17 receptor E. This is the presumed ligand-binding domain. Human putative interleukin-17 receptor E-like consists only of this domain.
Statistics
?
PSSM-Id: 464460
Aligned: 12 rows
Threshold Bit Score: 400.008
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6HG4_B        51 VLRCQKETD-------------------------------CDLCLRVA----------VHLAVHGhw--eeP--EDEEKF 85 
XP_017193892  71 VLRCRQETD-------------------------------CDLCVRVA----------VHLAVRGpwe-erE--EEEEQF 106
XP_013001754  71 VLRCHQETS-------------------------------CDLCVRVT----------VHLAVHIlsghreE--PEDKKW 107
Q8NAC3       142 VLRCQKETD-------------------------------CDLCLRVA----------VHLAVHGhw--eeP--EDEEKF 176 human
XP_009236997  39 PLASHTDDSftgssahipcrtwwa-lfstkpwcvrvwhcsHCLCQHLLsgrsglqwgfFHLLVQK------S--KKSSTF 109
XP_007500267  87 VLQCREESN-------------------------------CDLCVRVT----------LYLTVQEprk-edP--DEGGLQ 122
NP_001164036  71 VLRCPQETD-------------------------------CALCVRVV----------VHLAVHGhw--eeP--EE---- 101
XP_010815895  39 LLASRMDGSftgrsaqiphhiqpaphlspkpwcaccchcpHCWCLHLVsgpsglqwgwLRLLVQK------S--EKSYKF 110
XP_023353935  69 VLQCRGERN-------------------------------CVPCVRVT----------LHLTVQEprk-eeS--DEVWLR 104 Tasmanian devil
XP_014306829  39 LLVSHMDDSftersahipchtl------phtrgawlwccpCCLCLHLVstpsdlqrswFHRLVQK------S--KKSYMF 104 little brown bat
XP_025305986  39 LLASHMEDTltgrsacipchtqlalpvslkpwcvqlwlcpYYLCLHLVsdssglrggwFYLLVQK------Y--KKSHKF 110 dingo
XP_023403706  71 VLRCYHETD-------------------------------CDLCVRVD----------VHLAVHGhwekpedeelfrgas 109 African savanna...
6HG4_B        86 GGAADSGVEEPRNASLQAQVVLSFQAYPTA--------------RCVLLEVQVPAALVQFGQSVgsvvydcfeaalgsev 151
XP_017193892 107 GAAASPELEDSRNAALQARVVLSFQAYRTT--------------RCVLLEVQVPAALARPGPSAgsvvfdcfeaalgaev 172
XP_013001754 108 GGTAEPELKEPGNASLQAQVVLSFQAYPTA--------------RCVLLEVQVPAARVRPGQSVgslvfdcfeaalgaev 173
Q8NAC3       177 GGAADSGVEEPRNASLQAQVVLSFQAYPTA--------------RCVLLEVQVPAALVQFGQSVgsvvydcfeaalgsev 242 human
XP_009236997 110 KFCRRHKMPAPAQRKLLPSRHLSEKSHHISipspdishkglrskRTQPSDPEAWESLPRLDSQR---------------- 173
XP_007500267 123 EDAELTSGPWPRNESLEAEVILSFKDFLSN--------------RCVLVEVEVSPSMVQPGQNVgylvfdcfrapvgdev 188
NP_001164036 102 AGKSDSELQGPRNASLQAQVVLSFQAYPIA--------------RCALLEVQVPADLVQPGQSVgsavfdcfeaglgaev 167
XP_010815895 111 WLCRRHRMPASAQRKLLSSCCLSEKGHHNSslspdsshkglrskRTQPVDPEAGEGLSRSGSQK---------------- 174
XP_023353935 105 EDAELTSHPWPRNESLQAKVILSFQAYLSD--------------RCVLVKIEVPAAMVQPGQNVgslvfdcfk--aplge 168 Tasmanian devil
XP_014306829 105 QFCRRHRMPASAQRKLLTHCCLSEKDHQISapspdisqnglrfkRTQPSDPEAVEGLPRQDSQR---------------- 168 little brown bat
XP_025305986 111 RFCRRHKMPAYAQRKLMSSCCLSEKGHHIAvpspdishkglrskRTQPADPKAVEDLPRPSSQR---------------- 174 dingo
XP_023403706 110 DPEPREPG----NASLQSQVVLSFQAYPTA--------------RCVLLEVQVPASLVPSGQSVgsvvfdcfeaalggev 171 African savanna...
6HG4_B       152 riwsYTQPRYEKELqhtqqLPDCRGLEV------WNSIPSC--WALPWLNVSADGDnvhlvlqvseeqhfglslywnqvq 223
XP_017193892 173 rlwsYTQPRYQKELnvtqlLPDCKGLEV------QDSIQSC--WALPWLSVSAEGDlvhlvldvpeeqrfglalyrsqah 244
XP_013001754 174 qiwsYTQPRYQKELnltqqLP-----------------------VLPWLSVAADGDnvqlvlnvsrvqrfglllywsqvq 230
Q8NAC3       243 riwsYTQPRYEKELnhtqqLPDCRGLEV------WNSIPSC--WALPWLNVSADGDnvhlvlnvseeqhfglslywnqvq 314 human
XP_009236997 174 ----HGGPEFSFDL-----LPEARAIRVtissgpEVSVRLChqWALECEELSSPYD------------------------ 220
XP_007500267 189 wiwsYTQPRYQKELnhtqqLPDCIKPEL------WNNVQSC--WVLPWFNISAEGDavqlvmdvsaeqnyv-lflywnqt 259
NP_001164036 168 riwsYTKPRYQKELnvtqqLPDCRGLEV------QDSIQSC--WALPWLNVSTDGDnvllildvskeqkfgfllywdqaq 239
XP_010815895 175 ----LGGPEFSFDL-----LPETRAIQVtippgpEVSVRLChqWALECEDLSHPFD------------------------ 221
XP_023353935 169 evriYTEPPYEKELshiqqVPdcvrpelq--------nnvpscfVLPWFNISSEGDdiqlvmdisteqnyf-lslywnqs 239 Tasmanian devil
XP_014306829 169 ----HKGPEFSFDL-----LPEARAIRVsipsdpEVSVRLChqWALECEELSSPFD------------------------ 215 little brown bat
XP_025305986 175 ----HEGPEFSFDL-----LSEARAIQVtippgpEVSVRLChqWVLECEELSSPFD------------------------ 221 dingo
XP_023403706 172 qiwsYTQPRYQKELnltqkLPDCRGLEV------RDSIQSC--WALPWLNLSADGDnlrlvldvsegqrfglslywdqvq 243 African savanna...
6HG4_B       224 gppkprWHKQLTGPQIITLQHTDLVPCLCIQVW-PLEPDSVRTNICPFREDPRAH-QNLWQAARLRL-------LTLQSW 294
XP_017193892 245 gaprpwWHRNLTGPQTITLNHTDLLPCLCIQVW-PLEPDSVRTSTCPFREDPRAL-RNLWRAARPRL-------LPPHSW 315
XP_013001754 231 gplkpwWHRNLTGPQTITLNHTDLVPCLCIQVW-PLQPDPVRTSICPFKEDPRAH-RNLWRAAHLRL-------LSPRSW 301
Q8NAC3       315 gppkprWHKNLTGPQIITLNHTDLVPCLCIQVW-PLEPDSVRTNICPFREDPRAH-QNLWQAARLQL-------LTLQSW 385 human
XP_009236997 221 ------VQKIVSGGHTVELPYEFLLPCLCIEAS-YLQEDTVRRKKCPFQSWPEAYgSDFWKSVHFTD-------YSQHTQ 286
XP_007500267 260 qglstrFHEVLTGPHNITVNNTDLVPCLCIQMW-PNVLDAIRNSHCPFQKDPRAH-KNLWNQSKLNLtfstlwgETALSW 337
NP_001164036 240 gplkslLYKNLTGPQNITLNHTDLVPCLCIQLW-SQEPDSVRTSFCPFKKDPRAH-RNLWHMARLRV-------QSSGSW 310
XP_010815895 222 ------AQKIVPGSHTVDLPYEFLLPCLCIEAS-YLQEDTVRRKKCPFQDQPEAYgSDFWESMNFTD-------HSQHNQ 287
XP_023353935 240 gnrktkFLEVLTGPQNITLNQTDLVPCLCIEMWiKEEEDAIRNYLCPFKEDPRAH-KNLWNQTKLKLkf---lgTRSLSW 315 Tasmanian devil
XP_014306829 216 ------VQKTVSRGHTVDLPYEFLLPCLCIEAS-YLQEDTVRRKKCPFQSWPEAYgSDFWKSVNFTD-------YSQHSQ 281 little brown bat
XP_025305986 222 ------TQKIVSGGHAVDLPYEFLLPCLCIEAS-YLQEDTVRRKKCPFQNWPEAYgSDFWKSVHFTD-------YSQHSQ 287 dingo
XP_023403706 244 gppkprWQRNMTGPQNFTLNHTELVPCLCIQMW-PLEPDSIRTNLCPFREDPRAH-RNLWRATRLRL-------LSPLAW 314 African savanna...
6HG4_B       295 LLDAP---CSLPAEAALCWRAPGGDPCQPLVPPLSWEQvtvDKVLEFPLLKGHPNLCVQVQSSEKLQLqECLWADslG-- 369
XP_017193892 316 RLDAP---CSLPAEATLCWQAPGGGPCRPLAPPLPRDNvtvNKAHEFPLLRGHPNLCIQVSSWEKLQLqECLWADtlG-- 390
XP_013001754 302 RLDAP---CSLPAEVTLCWQSPGGDPCQPLTPPLSPENvtvNTAIKFPVLKGHPNLCVQVRSWKKVQLhECLWSDslG-- 376
Q8NAC3       386 LLDAP---CSLPAEAALCWRAPGGDPCQPLVPPLSWENvtvDKVLEFPLLKGHPNLCVQVNSSEKLQLqECLWADslG-- 460 human
XP_009236997 287 MVMALtlrCPLKLEAALCQRHDWHTLCKDLPNATARES---DGWYVLEQVDLHPQLCFKFSFGNSSHV-ECPHQT--G-- 358
XP_007500267 338 MVKAP---CPLSAEMVLCWQPVGSELCHPLPLPLPRENvivNTLQHLPMLTLHPNICLQVWSRGKPQIqKCPPKDvlG-- 412
NP_001164036 311 LLDTP---CSLRTEVALCWQAPDQSPCQPLVPPMPQKNvtmNRPFEFPLVKEHPNLCVQVSSWEKVELqECLWADslG-- 385
XP_010815895 288 MVMAVtlrCPLKLEASLCQRRGWPTLCEDLPNAMARES---EGWYVVEKVDLHPQLCFKFSFGNSSHV-ECPHRT--F-- 359
XP_023353935 316 MVEAP---CSLSAEIILCWKSVDSELCYPLPVPLPQKNvtlNKFQDLPLLTLHPNVCVQVWSGEKLQIqECPQENilG-- 390 Tasmanian devil
XP_014306829 282 MVMAPtlrCPLKLEASLCQRQGGNTLCEDLPNATARES---EGWYVLEKVDLHPQLCFKFSFGNSSHI-ECPHQT----- 352 little brown bat
XP_025305986 288 MVMALtlrCPLKLQASLCQRQNWHTFCEDLPNATAQEA---EGWYVLEGVDLHPQLCFKFSFRNSSHV-ECPHRTaqLlp 363 dingo
XP_023403706 315 QMDAP---CALPAEAALCWRAPGGGPCQPLVPPLPRENvtvNKALEFPLLKGHPNLCVQVSSWEKLQLeECLWADslG-- 389 African savanna...
6HG4_B       370 -----------------PL---------KDDVLLLETRGPQDQRSLCALEPSG------CTSLPSKASTRAAR--LGEYL 415
XP_017193892 391 -----------------PL---------RDDMLLVETRGPRHNRTLCALEHSG------CTPLPSRASTRAAR--VGEHL 436
XP_013001754 377 -----------------PL---------KDDVLLVEIQGPHDNRSLCALEPSG------CTPLPSRAATRAAR--LGEQL 422
Q8NAC3       461 -----------------PL---------KDDVLLLETRGPQDNRSLCALEPSG------CTSLPSKASTRAAR--LGEYL 506 human
XP_009236997 359 -----------------SLtswnvsmdtQAQQLILHFSSRMHATFSAAWSHPGlgqdtlVPPVYTVSQARGSSpvTLDLI 421
XP_007500267 413 -----------------PL---------RDDMLLLETWGSVENHSFCAMEISG------CTPLPSLAHTRAAF--LGKQL 458
NP_001164036 386 -----------------PF---------KDDMLLVEMKTDLNDTSVCALEPSG------CTPLPSVASTRAAR--LGEQL 431
XP_010815895 360 -----------------AApswnvsmdtQAQQVVLHFSSRTHVTFSAAWNHPGlgqdsvVPPVYSVSQTQGSTpvTLDLI 422
XP_023353935 391 -----------------PL---------KNDMLLLETWGPLQNHSFCAMETSG------CTPLPSTAHTRAAF--FGKQL 436 Tasmanian devil
XP_014306829 353 ------------------ApswnvsmdtQAQQLILHFSTRTRATFSAAWSHPDmgrdslLPPVYSISQTQGSSpvTLELI 414 little brown bat
XP_025305986 364 psanrvspiipfptlaaPSwnvs--mdtQAQQLVLHFSSRIHATFSAAWSHPSlgqdgfVPPVYSISQTQGSSpvTLDLI 441 dingo
XP_023403706 390 -----------------PL---------RDDMLLVETRGPQDNRSLCALEPSG------CTPLSSKASTKAAR--LGEQL 435 African savanna...
6HG4_B       416 LQDLQSGQCLQLW-DDDLGALWA---CP 439
XP_017193892 437 LQDLESGQCLQLW-DDDRGAFWA---CP 460
XP_013001754 423 LQDLHAGQCLQLW-DDDVGALWA---CP 446
Q8NAC3       507 LQDLQSGQCLQLW-DDDLGALWA---CP 530 human
XP_009236997 422 IPFLRPGCCVLVW-RSDVQFAWKhllCP 448
XP_007500267 459 LQDLQSGQCVQLW--NATGTLWA---CS 481
NP_001164036 432 LLDFRTHQCMQLWnDDDLGSLWA---CP 456
XP_010815895 423 VPFLRPGGCVLVW-RSDVQFAWKrllCP 449
XP_023353935 437 LQDLQSGQCVQLW--NDTGILWA---CS 459 Tasmanian devil
XP_014306829 415 IPFLRPGACVLVW-RSDVQFAWKhllCP 441 little brown bat
XP_025305986 442 IPFLKPGSCVLVW-RSDVQFSWKhllCP 468 dingo
XP_023403706 436 LGDLQSGRCEQLW-NDDLGVLWA---CP 459 African savanna elephant
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap