2CZT,4ORY,3U9P,4K19,4ES7,3EYC,1BSY,1EXS,4R0B,2RA6,3L4R,1HN2,1E00,4WFV,3FIQ,1E5P,1GM6,1EW3,2A2U,3KFI,1ZNK,3APW,1O8V,3AKM,2LFO,2FTB,1P6P,1EAL,1GGL,6MCV,1KQX,2FLJ,1MDC,1JJX,2OVA,3SAO,1KT3,1OBQ,1GKA,2HZQ,1N0S


Conserved Protein Domain Family
Lipocalin
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pfam00061: Lipocalin 
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Lipocalin / cytosolic fatty-acid binding protein family
Lipocalins are transporters for small hydrophobic molecules, such as lipids, steroid hormones, bilins, and retinoids. The family also encompasses the enzyme prostaglandin D synthase (EC:5.3.99.2). Alignment subsumes both the lipocalin and fatty acid binding protein signatures from PROSITE. This is supported on structural and functional grounds. The structure is an eight-stranded beta barrel.
Links
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Statistics
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PSSM-Id: 395015
Aligned: 155 rows
Threshold Bit Score: 31.2565
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2CZT_A  18 LGRWYSAGLASnsswfREKKAVLYMAKTVVAPS-TEGGLNLTSTFLRKNQCETKIMVLQPAGAPGHYTYSSPHSGSIH-- 94  house mouse
4ES7_A  49 YGKWYNLAIGStcpwlKKIMDRMTVSTLVLGEGaTEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITM-- 126 human
O70160  41 YGKWYSLAIGStcpwlKRIKDRLSVDTMVLGKGaTEAQMSTTRTHWRRGVCERTSGFYEKTDTAGKYLYSNPKWNLTM-- 118 domestic guinea pig
O93588  29 VGKWHPIGMASklpelTPYEQKISPMDHIVEV--IDGDMKLTANYMSDGVSKEATAMLKHTDKPGVFKFT------DG-- 98  common lizard
O93589  25 VGKWHPIGMASklpelTPYEQKISPMDHIVEV--TDGDMKLTANYMSDGVCKTSVLVLKHTDKPGVFKVP------DG-- 94  common lizard
A2AJB7  41 LGFWYEIALASkmgayGLAHKEEKMGAMVVEl--KENLLALTTTYYNEGHCVLEKVAATQVDGSAKYKVTR--ISGEK-- 114 house mouse
Q924P3  33 AGFWKEVAVASdqklvLKAQRRVEGLFLTF----SGGNVTVKAVYNSSGSCVTESSLGSERDTVGEFA-----FPGNR-- 101 house mouse
2OVA_A  28 AGTWLLVAVGSaarflQEQGHRAEATTLHVAP--QGTAMAVSTFRKLDGICWQVRQLWGDTGVLGRFLLQ---ARGARga 102 human
3SAO_B   9 AGKWYIVALASntdffLAEKGKMKMVMARISFL-GEDELEVSYAAPSPKGCRKWETTFKKTSDDGEVYYS---EEAEK-- 82  chicken
Q8UWH4  47 AGMWHMMAAVSncpvfLGMKDKMTSSATAVSFT-PEGHMTMETVIPLPEECKKIMMLFQQSGQAGHYIGTE--KGEKR-- 121 chicken

2CZT_A  95 -SVSVVEANYDEYALLFSRGTKGpGqDFRMATLYSRTQTLKDELke-kFTTFSKAQGLTEEDIVFLPQPD 162 house mouse
4ES7_A 127 -ESYVVHTNYDEYAIFLTKKFSRhHgPTITAKLYGRAPQLRETLlq-dFRVVAQGVGIPEDSIFTMADRG 194 human
O70160 119 -ESYVVHTNYDEYATVLTKKFSRhHgPTITAKLYGREPQLRDSLlq-gFREMALSVGIPEDSIFTMANRG 186 domestic guinea pig
O93588  99 -EVHVLDVDFEKYIMLYVKKS-----SHEALFLSARGPDVEDDIke-kFKKLVLEQSFPEANIKYFNAEQ 161 common lizard
O93589  95 -EVHVIKMLILKSISFFTSK----KpTHEALFLSARGSTGGDDIka-kFKKLVWEQIILEAHIKYLNVEQ 158 common lizard
A2AJB7 115 -EVVVVATDYMTYTVIDITSLVA-GaVHRAMKLYSRSLDNNGEAln-nFQKIALKHGFSETDIHILKHDL 181 house mouse
Q924P3 102 -EIHVLDTDYERYTILKLTLLWQ-GrNFHVLKYFTRSLENEDEPgfwlFREMTADQGL------YMLARH 163 house mouse
2OVA_A 103 vHVVVAETDYQSFAVLYLERA-----GQLSVKLYARSLPVSDSVls-gFEQRVQEAHLTEDQIFYFPKYG 166 human
3SAO_B  83 -TVEVLDTDYKSYAVIFATRV-KdGrTLHMMRLYSRSREVSPTAma-iFRKLARERNYTDEMVAVLPSQa 149 chicken
Q8UWH4 122 -DLRVMDTDYEHYAIVYSQQKDS-QePSTMLQLYTRNQDMSPQLlq-kFKELFHSMGLTEDMLVVLPHSD 188 chicken
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