Conserved Protein Domain Family
DDRGK

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pfam09756: DDRGK 
DDRGK domain
This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.
Statistics
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Structure
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pfam09756 is classified as a model that may span more than one domain.
pfam09756 is the only member of the superfamily cl25550
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
A0BRS7        84 VQNAEQQAKREARKQKKQQQQQYVRQQIEMLEKKNEKRSKEYEEK-----ERQREQQEQEEEEWRKKIEAEQKQKEQEEF 158 Paramecium tetr...
XP_018653061  98 KKVGSKKAAKLAEKERRKEEREAEERYREHQRKIEDMEIEKRKKA-----EEAEEKAAAAAAAAEAKRREEEAAREQAEY 172
P34623       107 KKIGKRKAAKLQAKEEKRQMREYEVREREERKRREEEREKKRDEE-----RAKEEADEKAEEERLRKEREEKERKEHEEY 181 Caenorhabditis ...
Q295B1       109 EKMGAKKRAKMEAKEQKRLHREQELIDREQRKVKEAKEEAERKQQ-----EDFQEEADRKRAEAERLVKEERERKEHEEY 183 Drosophila pseu...
Q80WW9       116 GKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKE-----EERLRLKEEQKEEEERKAQEEQARREHEEY 190 house mouse
Q6P0E5       103 GKVGAKKQRKLEEKQARKAQREAEQEEREERKRLQELRDQERQKE-----EEKERQQEQKQEEELQRVKEEQERREEEEY 177 zebrafish
CAG06621      99 aKIGTKKQRKLEEKQARKAQREVEMEEREERKRMQELREQEKRQD-----EEKERLLEQKQEEDRRRAKEEQERQEEEEY 173
Q55CM7       132 KKIGKKKLEKLKLKDEKRKAREYQEYLREEKKKTDLEKEEALKEK-----RLEEKENEKLRKEEEERIRIEKERKEDEEY 206 Dictyostelium d...
Q4UBS5        78 KVLTAKQRKRQEIKEERRRLKALEDEEREERRKLLAKK------------QEQIEAKRLEREALMEEQERKKREEEEKAY 145 Theileria annulata
XP_001609113  60 RSLTVKQRKKQELKEAKRQQRALIDEERKEKEKLKQQR------------DDLREKRREEKERQRQEEEEKRAAKAQEAY 127
Q246A2       102 qtRTQRELAREAKKQQKRQQREAMQQYYEQREQRDNQKKSKYEER-----DRLRELEEQKKEEEQRKQEELQRIKEQEEF 176 Tetrahymena the...
KOB60152     110 KELNEVSKLKNNLKGKTYNSNIGEEMLEENKEKQHGNYVGEYFDRndmilKERIFEYAKHKTSIDMLKHPDDIKRNSKDL 189 Plasmodium falc...
A0BRS7       159 DKWSSMFQVEQSGTMKLSAEEEEQktkeFNERLANYIKLRKVVQLEEVSAELGISTTEVVDKIKQLEMLGSLNGLIDERG 238 Paramecium tetr...
XP_018653061 173 ERLKQEFSIEEEGLDAQQQDDKAKa--lINAQIIAAIEEAKIIPVEHLAINLNLKTEVCIENIKALMSSGRLTGVLDDRG 250
P34623       182 LAMKASFAIEEEGTDAIEGEEAEN----LIRDFVDYVKTNKVVNIDELSSHFGLKSEDAVNRLQHFIEEGLVQGVMDDRG 257 Caenorhabditis ...
Q295B1       184 LKMKAGFSVEEEGFEEGDADDQDN----LLADFIQYIKDNKVVLLEDLAVAFKLKTQQAIERIQDLQANGTLTGVIDDRG 259 Drosophila pseu...
Q80WW9       191 LKLKEAFVVEEEGVSETMTEEQSHs---FLTEFINYIKKSKVVLLEDLAFQMGLRTQDAINRIQDLLTEGTLTGVIDDRG 267 house mouse
Q6P0E5       178 QRLKESFIIEDQGEAEELTEHESQs---LLQEFIQYVQKSKVVLLEDLASQFGLRTQDAIARLQDLIADGSLTGVIDDRG 254 zebrafish
CAG06621     174 LRLKASFVVEEQGEEDQLTEDQSRn---LLKEFIEYIENNKVVLLEDLASHFGMRTQDAIDRLQNLLAEGSITGVIDDRG 250
Q55CM7       207 NLLKSQISLQESGITKNEDYDKS-----LLQLFIKYLKEHKICLLEDIAIEFNIKTNEVIDRIKTLDKQGLISGVIDDRG 281 Dictyostelium d...
Q4UBS5       146 QELVSTFVVESEGTISETNQY-------TVDDFIDYIVSKKLSNVEELSARFSLKASEVIKRIQELEDQNKIFGLLDDQG 218 Theileria annulata
XP_001609113 128 EAIASEFVVEQEGTIQDHEVF-------DVEDFINFVIEKKMTTIVELAAKFDLDHKVVASRLNDLELQGRLFGLLDERG 200
Q246A2       177 ENWKKFMEVEESGQEKMSAEEEERyyreLNEKITNYIKLRKVVVLEEMTGEFKITTQEVIDRIKSLEINKQINGIIDERG 256 Tetrahymena the...
KOB60152     190 KKWKSQVITKKYADDWLSSDV-------LLSCFLNFIKLKKYVNITELSVKFQTTTDDIREKLEELEEQDMINGVLDEKG 262 Plasmodium falc...
A0BRS7       239 KYIHIRQNEIESLINYINARGRM-TRSELLNESNRIIK 275 Paramecium tetraurelia
XP_018653061 251 KVIHITNDEYEAVAQYIEKCGRV-TLSELVENGHKLIR 287
P34623       258 KFIYISDEEFAAVAKFINQRGRV-SIHEIAEQSNRLIR 294 Caenorhabditis elegans
Q295B1       260 KFIYVSEEELAAVAKFIKQRGRV-SIVELAESSNNLIN 296 Drosophila pseudoobscura pseudoobscura
Q80WW9       268 KFIYITPEELAAVANFIRQRGRV-SITELAQASNSLIS 304 house mouse
Q6P0E5       255 KFIFITPEELNAVAQFIKQRGRV-SISELAQASNTLIN 291 zebrafish
CAG06621     251 KFISITPAELDSVARFIRQRGRV-SISELAQASNSLIN 287
Q55CM7       282 KFIYITKEEMEAVAKFVNKKGRV-NIEQIALESNRLID 318 Dictyostelium discoideum
Q4UBS5       219 RYVYITDDEAESVISYLKSKGKLhKQRDLLSFFNSTIS 256 Theileria annulata
XP_001609113 201 RYLYISDSELDALDHYINKEGRIdKYTGLTSFCNATIS 238
Q246A2       257 KYIYITPTELESVKNYIISKGRV-SRSDLIAECNRLIK 293 Tetrahymena thermophila SB210
KOB60152     263 NYIYLSQEEINKLCFEIQSKGKVnTHDDFVKICNKVIS 300 Plasmodium falciparum HB3
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