1ZM8,6LYF,3S5B


Conserved Protein Domain Family
Endonuclease_NS

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pfam01223: Endonuclease_NS 
DNA/RNA non-specific endonuclease
Statistics
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PSSM-Id: 460120
Aligned: 56 rows
Threshold Bit Score: 69.3867
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1ZM8_A        27 LGNPSGATPTKLTPDNyl-mVKNQYALSYNNS--KGTANWVAWQLNSSWLGNAe------RQD------NFRPDKTLPAG 91  Anabaena sp.
Q9VAU2       106 IPSATFAVGFSFNGR-----FMELYRNCFDGY-----SLAFQHSIYKAYRYVNtv---prPNP------TWQSDQLSGGF 166 fruit fly
Q9VAU3       102 CPATMYRVGYNVGNNQ----FLELYRACFDTR--AVRAIFVEHRVYGKPFYITrp------------cvQFSSDGVISGA 163 fruit fly
O33735        73 RTTERVYKKSGQSTKPv-----tVSNIHYSVLdgYGRSGEAYGIITKDMIDMSagy--reKWEskpepsGWYSYFFKNTN 145 Streptococcus p...
AAM79702      60 ETSPNYYKVLGESGIVen-lFPPKGQIVYGGLdsLGRTLTVRGTLTFNNVLGSynirkdfKRSkaetlsGWLGNKNGEVY 138
Q7DAK9        70 NDSPNYYKTLGTSQITpa-lFPKAGDILYSKLdeLGRTRTARGTLTYANVEGSygv--rqSFGknqnpaGWTGNPNHVKY 146 Streptococcus p...
WP_000865436  87 SGGKAAIEVNNGQSSLdi-aTWKENKVIYGDLdsLNRTTFVTAYLDRKNLGRSe-----gRERqvwqptGWHQKQIDGDP 160 eubacteria
Q8E067        86 QSGAFIINQNKTDLNAkv-sSAPYAINEIKKVnnQIVPTKANALLTKATRQYRnre-etgNGRtywkpaGWHQINGLKGS 163 Streptococcus a...
Q9CJ50        41 NSSQVSTKSLASSVKQapltFKNQRQMVMANTdaLGRAVDSHIQLKDSQEPKVk------REPltynpvGWHNYNFYYKK 114 Lactococcus lac...
Q7QH21        92 DNGTIVRVGFSVDEAR----FAALYEVCFDER--NLRTHYTKHRLTPHNDHHQra----vKRP------SFLQGEFYGDL 155 Anopheles gambi...
1ZM8_A        92 wVRVT-PSMYSGS-------G-----------------YARGHIAPS-ADRTk------TTEdNAATFLM-TNMMPQTPD 138 Anabaena sp.
Q9VAU2       167 dNA---YEGRATQaclltnlGavqp----------qckFDRGHMTPA-SAFI-------STElKKSTFRY-LNAIPQYRG 224 fruit fly
Q9VAU3       164 dEAS--YTVRNIHgtfrrlfGnnqnyip----nnrdviINRGHLAAS-ADFFf------GDQ-LCATFKY-VNAVPQFKS 228 fruit fly
O33735       146 qRATEsDYKHSPKnvskisnNikasillsngnvrngylFDRSHLIAD------------SLGgRPFRNNLiTGTRTQNVG 213 Streptococcus p...
AAM79702     139 vIKGLgDDSYQGYf------------------------WNKSHLIAD------------SLGgDALRVNAiTGTRTQNVG 182
Q7DAK9       147 kIEWLnGLSYVGDf------------------------WNRSHLIAD------------SLGgDALRVNAvTGTRTQNVG 190 Streptococcus p...
WP_000865436 161 i-------------------------------------VNRGHLLAYtSSFNfdidgnfKIGeNGSQDNP-KNLATQTAF 202 eubacteria
Q8E067       164 yNHA----------------------------------VDRGHLIGY-ALVGs------LRGfDASTSNP-KNIATQAAW 201 Streptococcus a...
Q9CJ50       115 sDGSIgkm----------------------------wlMARGHLVGY------------QFSgLNNEA---RNLVPETAW 151 Lactococcus lac...
Q7QH21       156 kMATL-YSFAAQHatlarilSsparadal-lsskkglfFARGHLAAK-SDFVf------GAH-QRASFWF-MNVAPQWQR 224 Anopheles gambi...
1ZM8_A       139 NN--R--NT-------WGNLEDYCREL--VSQG-K--------------ELYIVAGPNGSLGKPl--------------- 175 Anabaena sp.
Q9VAU2       225 VN--R--GK-------WKAVETWVNNM--VRGLyDnpiinnvqiprtydVLKVCIGALGVHRLRhntnnnmi-----piy 286 fruit fly
Q9VAU3       229 IN--D--GN-------WETIERFVRNS--VTG--Nn-------------FVNVRTGARGVLSLPsgnrpk--------nv 272 fruit fly
O33735       214 NNdrK--GG-------MQYIENKVLDH--IKRNpKv-------------HVYYKATPVYQGSEL---------------- 253 Streptococcus p...
AAM79702     183 GRsgN--GG-------MRYTEIKSQKW--LEAHrDg-------------YLYYEAMPIYQGNEL---------------- 222
Q7DAK9       191 GRdqK--GG-------MRYTEQRAQEW--LEANrDg-------------YLYYEAAPIYNADEL---------------- 230 Streptococcus p...
WP_000865436 203 SN--Q--KV-------QTHYEKLVRDAqkLK---Gn-------------KVIYQIVTVFRGKEL---------------- 239 eubacteria
Q8E067       202 AN--QanSNqs---tgQNYYETLVRKA--LDR--Hk-------------TVRYRVTLIYDRDNL---------------- 243 Streptococcus a...
Q9CJ50       152 FNggNftGTndgntasMLYYENRLDSW--LANHpNy-------------YLDYQVTPLYEGNEL---------------- 200 Lactococcus lac...
Q7QH21       225 FN--G--FS-------WQRIESGVKAY--VAAN-Dl-------------RLTVYTGTYGVLKLLdgngdgqeifldydan 277 Anopheles gambi...
1ZM8_A       176 ---kGKVTVPKSTWKIVVVLDSPGSgleGITANTRVIavnipndp------elnndwrAYkvsvdELESL-TG--YDFLS 243 Anabaena sp.
Q9VAU2       287 lldnNKIPVPEWMYKIVSHLSG-DKwvmLTYNDVSLPnqqaln----------qichvIPchpglNLNTKdVG--HTVCC 353 fruit fly
Q9VAU3       273 flsgNRNPVPQWMYKIVRNANNQPIvafLTLNNIYARqrpaa-----------pnfcqPVncpvaLVNTAqAG--FSFCC 339 fruit fly
O33735       254 --------LPRAVLVSALSSDG------------------------------------FIdetvrVFNNV-AGfnIDYQN 288 Streptococcus p...
AAM79702     223 --------VPRAVVVSVLSSDN------------------------------------TInekviVYNVA-NGytIDYNQ 257
Q7DAK9       231 --------IPRAVVVSMQSSDN------------------------------------TInekvlVYNTA-NGytINYHN 265 Streptococcus p...
WP_000865436 240 --------MPRGYWLQAIDSAG------------------------------------TLnfnvyEYNVQ-PNvvFNYEE 274 eubacteria
Q8E067       244 --------LSSGSHIEAKSSDG------------------------------------SLefnvfIPNVQ-SGllFDYAT 278 Streptococcus a...
Q9CJ50       201 --------LPRQIRLAYVGIDK-------NGQTLSIKlgggr------------eksgNGgatvvVLDNVaPNakINYAD 253 Lactococcus lac...
Q7QH21       278 repaGKVPAPALFYKVLLDEANDAGlalVGVNNPHATpeeiaadyvvckdvsdavrwlRW-----DRNSIeDG--YVYAC 350 Anopheles gambi...
1ZM8_A       244 NVSPN 248 Anabaena sp.
Q9VAU2       354 DPYRF 358 fruit fly
Q9VAU3       340 NPATF 344 fruit fly
O33735       289 GGLLT 293 Streptococcus pyogenes
AAM79702     258 GTFSA 262
Q7DAK9       266 GTPTQ 270 Streptococcus pyogenes serotype M1
WP_000865436 275 GTSQI 279 eubacteria
Q8E067       279 GKVKQ 283 Streptococcus agalactiae serogroup V
Q9CJ50       254 GTAVN 258 Lactococcus lactis subsp. lactis
Q7QH21       351 DVNEF 355 Anopheles gambiae str. PEST
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