3V69


Conserved Protein Domain Family
MOEP19

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pfam16005: MOEP19 
KH-like RNA-binding domain
MOEP19 is a family of mammalian KH-like RNA-binding motifs. The family is expressed during early embryogenesis. It appears to effect an early form of molecular asymmetry within the murine oocyte cytoplasm. The family marks a defined cortical cytoplasmic domain in oocytes and provides evidence for mammalian oocyte polarity and a form of pre-patterning that persists in zygotes and early embryos through the morula stage.
Statistics
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PSSM-Id: 464969
Aligned: 24 rows
Threshold Bit Score: 86.1544
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3V69_A        44 KLPKWFHVECLEDPKRLYVEPRLLEIMFGKDGEHIPHLESMLHTLIHVNVWGP-ERRAEIWIFGPPPFRRDVDRMLTDLA 122
2_pfamImport   1 ILPWLNVLEDLIDPKVLEVPPWLLEPMFGPDRSRISFFEKVGKTMIELQTSES-SAHTEIVVYGDLTYRARTTWMLQCLA 79 
ACJ74003      10 IPPWVKVPEDLKDPEVLQVQTRLLEAMFGPDGSRIPYIEQVSKAMLELKALES-SDLTEVVVYGSYMYKLRTKWMLQSMA 88 
XP_235194     10 IPPWVKVPEDLKDPEVFQVHTLVLKSLFGPQGSRMPHIEQVSRAMFELKILES-SGLTEVLIYGSCNHKLRAKWMLQSMA 88 
XP_013848085  11 ILSWVGAPEDFTEPEVFQVQTRLLEALFGPEGSRIPYVEKVSKVMLEMKALES-SDLTEVMVYGPYLYKFRTKWMLQSMA 89 
XP_002714465  20 QQPWWKVPENFDAPVVVYLEEEQEEQIFGHNDAHLRCIEVHSQTLIQLESWFTaRGQTRVTIVGPPRARQWLMDMIWSLG 99 
ELK00156      35 EEPWWINPENFYLPLVFYMEEDQEERIFGRLDTDLHCIEVHSHTFIQLEGWFTaTGQTRVTIVGPPEARQWLFLMILSMG 114
XP_004770790  32 TQQYWCKFKHFLKPSVLNVEARLLEKIFGPSRVLLPGFEREFKVVLQMRKPNS-EGKVEIFILGRRRYRKRAKRLIRILT 110
F6SZT2        29 KRFSWFHSEFLKNPKVVRLEVWLVEKIFGRDRERIPHVQGMSQILIHVNRLDP-NGEAEILVFGRPSYQEDTIKMIMNLA 107 Rhesus monkey
P85965        11 IPPWVKVPEDLTDPEVFQVQSLVLKYLFGPQGSRMSHIEQVSQAMFELKNLESpEELIEVFIYGYQSIKVRAKWLLQSMA 90  house mouse
3V69_A       123 HYCRMK 128
2_pfamImport  80 ERHRRQ 85 
ACJ74003      89 EWHRQR 94 
XP_235194     89 ERYRLR 94 
XP_013848085  90 EWHCQR 95 
XP_002714465 100 NRdpyl 105
ELK00156     115 SWDLDq 120
XP_004770790 111 Tkprrk 116
F6SZT2       108 DYHRQL 113 Rhesus monkey
P85965        91 ERYHLR 96  house mouse
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