Conserved Protein Domain Family
DERM

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pfam14704: DERM 
Dermatopontin
Members of this family mediate cell adhesion via cell surface integrin binding. They also induce haemagglutination and aggregation of amebocytes.
Statistics
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PSSM-Id: 464273
Aligned: 52 rows
Threshold Bit Score: 110.85
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGD79681      117 STISEPFTLTCPEGQGVTTVSSEFNEDEG-DRI-FSLTCSDIGGqpqpPPTWTADYVNEFvSNDYDlysfppRDLTFTCP 194 
XP_004996527  673 GRAGQDFTLQCPDGQGFVSVKSESSGYNA-DKRiMKFGCADVG-----SNDANRVWKSYR-VDKPL------QTFDFTCP 739 
XP_004997497   38 TSFAQEFNVACPNGQGFRGLRSIHENEY--DRK-WRFLCEDVGYgp-nDNVAKFGTLEDR-KENYD------HPQTVVCP 106 
XP_004989977  702 GASGETFTLSCASGQGFVGVTSDAQNSAVgDRRdWGFACDDVG-----SNDANRVWNMHEeINSAR------GSFDFTCP 770 
XP_004990650  584 TAQTRPFSLMCDSGQGVVGLYSEYGSGY--DRVnWDIICSDIG-----SNDSPRLWSKHEdVHQLQ------EDFSFTCP 650 
XP_004990947  223 ADYQEPFGSYCETSTAITTISTQFAASST-DRR-WAFTCTKPTSg---GQVITSQTWSTPaYGKLG------TAFTVSCP 291  Salpingoeca r...
XP_004992868  217 NAAEETFASECPDFQAMKIFYSEYDSATQ-DRL-FQLGCSAIAD----GGSFPRNAWSSAtYGNLQ------AFFDFTCP 284  Salpingoeca r...
XP_004990650  227 FNIHGGFHAACPTGQALVRMAAYSANE---DRR-WRFLCADNIGg---PTDGNLVAFSQPtYNQLR------AAFSYDCP 293 
XP_004987838  206 NNFHDPFYVSCPGSTGMYEVHSYHNNYRE-DRR-WRYYCGSIGG----PTAGTKTGWSSAdYSLLN------HHHYFSCP 273 
XP_004989977  204 NDFQSPFYVTCPDNTGMYEVRSYHDNNQA-DRR-WRYYCDTIGG----PTAGSKTGWSSAdYSRLG------LRHTFSCP 271 
EGD79681      195 -TNEYLTGIESDAreariQASRGrenffaDRRWKFQCAK-LNG--GTLMNCA-FG--QDETWYRDPFDVSAP-SSSVITG 266 
XP_004996527  740 -DNYYLYGVETEYi---pFSAPSpprdvsDRVWTFNCAI-LHG--AELSDCQtSQ--HYAADDYT-FDFAAP-NDHVLVG 808 
XP_004997497  107 -RHHYLAGALSKF-----HGHYS------DRLWIWTCRQ-ATD--AVLSNCQ-RG--DYVNNWDEQFKFIAS-DNRVITG 167 
XP_004989977  771 hDSYYISGVTTSY-----LDSPN------DRLWGFQCSL-IFG--ATLGNCQlSS--SYSASTFN-FDYAVP-TGHVLVG 832 
XP_004990650  651 dGTSYLAGMTTTY-----DATAR------DRLWEFRCAT-VFG--AELVNCQqRTlySYG------VQFRAP-DGHVVVG 709 
XP_004990947  292 -SNTYITGVKSAY-----VSSFQ------DRVYSFQCTG-YENteISAVNCN-GA--VAVNAAGADFDFSTSsGAYVITS 355  Salpingoeca r...
XP_004992868  285 -PNTFVTGMRSQF-----ISSSL------DRAYSFQCSS-APNtdVSTTTCItTT----RNSLYATVDVFVN-ETYAITG 346  Salpingoeca r...
XP_004990650  294 -PNSYIRAVKSSY-----VFESL------DRVYSFQCQYiTG---ATLVDCVtVG----PNAFDADTGFNAG-TNRVFAG 353 
XP_004987838  274 -DNAYMRGMKTVF-----VADAN------DRVFSYQCQYiTS---ATLTNCY-TQ--NYRNTYDNPLSYNPG-SNRVLTG 334 
XP_004989977  272 -DNTYMRGMKSTF-----VADAN------DRVFSYQCQAiSS---ATLTNCI-TQ--PFQNIFDNALTFNAG-TKRVITG 332 
EGD79681      267 VSADVGAffADKvDPLWSFQKCQITC 292 
XP_004996527  809 FYSEYHT--GDIySRSFIFRTCKVTC 832 
XP_004997497  168 VNSYHDN--NKE-DRRFRFTTCRVDC 190 
XP_004989977  833 VKSSYST--SSG-SRSFQFRTCEVQC 855 
XP_004990650  710 VTSTYFA--TYR-KRTFQYRTCEVRC 732 
XP_004990947  356 LTSTFDS--STS-DREWTFTECKPQC 378  Salpingoeca rosetta
XP_004992868  347 VNALYDT--SGNvDRQFSLTACQLEC 370  Salpingoeca rosetta
XP_004990650  354 ISTTFGA--SQN-DRAFTYKLCRVQC 376 
XP_004987838  335 -----NS--PTR-DRAFNIRSCQVSC 352 
XP_004989977  333 ILSDYLA--SAM-DRTFHIRTCQVSC 355 
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