Conserved Protein Domain Family
CobM

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COG2875: CobM 
Precorrin-4 methylase [Coenzyme transport and metabolism]
Precorrin-4 methylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Statistics
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PSSM-Id: 442122
Aligned: 369 rows
Threshold Bit Score: 219.546
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013706202  31 APGKFYLVGTGPAGPEHATLKAMDTINKADLILCHPELQKLF--QSCLNGKKVE-Dpwkelwwhqgkmwimllpnlplee 107
WP_011007206   1 MAGKVVFIGAGPGDPELLTVKAVKYLSQAEVVVYAGSLVNAEvlKYARQDAEVY-N------------------------ 55 
WP_052846661   1 MKGKVVFIGAGPGDPELITVKAKNYIEDADVILYAGSLINPEilKWARKDAEIV-N------------------------ 55 
WP_011277312   2 KKGKVVFIGAGPGDPELITVRAKNVIEDADVVLYAGSLVNPQvlKWARKDAEIV-N------------------------ 56 
WP_013337006   1 MVGKVVFVGAGPGDPELITVKGMKYLQQADVVIYAGSLVNPEvlRWARPGAEIH-N------------------------ 55 
WP_013706566  31 KPGTFYVVGVGPAGPEHTTLRALEVIKGVDYILCEDKMVERF--KPYVKDKPVLaDpwkgmwdykgkpwee-lpkmklee 107
WP_013776789   1 MKGKVAFIGSGPGDPELITVKAKKYIEEADVILYAGSLVNPEilNWAKRDAEII-N------------------------ 55 
WP_014126992   1 MAGKVVFVGAGPGDPELITVKGMRYLQQADVVVYAGSLVNPEllKYAKPNAKIY-D------------------------ 55 
WP_089609838   1 METKVFIVAGGPGDAELMTLKGQRIIDSADRIFFSTRFTPQEmfSNTKSSCKFY-D------------------------ 55 
WP_126449743   1 MRGRVVFVGAGPGDPELITVKGRNYLEDADVVLYAGSLVNREilKYARREAEII-D------------------------ 55 
WP_013706202 108 rralveEKMRQRDKFVQRVKGLLDQGQKVVLLDGGDPTVYSRAYWLMEGLNDD--RVEIIPGVGALSACMAALKRPSTGG 185
WP_011007206  56 ------SASMVTEEIVKLMIQKAREGKLVARLKSGDPSIYGALWEEIIPLQLAgiEYEIVPGVTAALAAAAQLRIELTVP 129
WP_052846661  56 ------TAELTLEEITDLMIKKAKEGKLVARLKSGDFSIYGALMEELWALQDAgiDYELVPGITAAIAAASVLGIELTLP 129
WP_011277312  57 ------TASLTLEEITDIMIKKANEGKLIARLKSGDFSIYGALIEEIWALQDAgiPYELVPGITAAIATASVLGIELTLP 130
WP_013337006  56 ------SASMTLEEIVDIMITRAREGKLVVRLKSGDASIYGALLEEIIALREAgiPYEVVPGVTAALAAAAVLGIELTLP 129
WP_013706566 108 krafqeERIRIREEIVRQIKEKLAQGKTVALLDSGDPCLFGPSHWFSEGFEPQ--QVEIIPGVGAFTAAMAALKKSSIPA 185
WP_013776789  56 ------TAELTHEEIVNIMVKKAKEGKLVARLKSGDFSIYGALNEELQAIKKEgiDYELIPGITAAIAAASSLGIELTLP 129
WP_014126992  56 ------SASLTTEEIVDILVREASQGKLVVRLKSGDGGVYGALWEEILPLQALgiEFEIVPGITAALAAAAVMNIELTVP 129
WP_089609838  56 ------SFAYSYDEKLQLVKEAVSKKQITAFVTMGDPCLYGMIGGLTDRFENEqiDYEVIPGVSSFNAATALLKRGMTGL 129
WP_126449743  56 ------TASLTQEEISRIMVERAKEGKLVVRVKSGDFSIYGALMEELWSLQDAgiDYELVPGITAALGAASALGIELTLP 129
WP_013706202 186 E-ARFMSQTAGYcFFGKPDRD-DLARDF-ARISGTLVVYSGLKEANDIFTTLKK-YNPEDLPAAVVYFAGFPdKEKIVKG 261
WP_011007206 130 KrVQHVVITRAS-HRVPMRGSlKDVADFiLKTGAVAVIYTGVHVIDKVVKELEEgGLSPGTPVAVVYKATWP-DQKIIQG 207
WP_052846661 130 KvSQTVIITRAS-ASVPMEGSiKDFAPL-LNKGASLVIYTGVHVIDKVVEEIREaGISDDIPVAVVYKATWWgEQKIILG 207
WP_011277312 131 KiSQTVIITRAS-GAVPMEGSiKDYAPF-LMKGASMAIYTGVQLIDKVVRELKEgGVPDDMPVIVVYKATWP-EQKILKG 207
WP_013337006 130 KvAQTLIITRAS-ARVPMQGSiKDFAKA-MLIGATMAIYTGVHLIDKVVKELREaGVPDDTPVAVVYKATWP-DQVIIRG 206
WP_013706566 186 YdTRFVMQTSPYfFTG--SGK-EMLGEL-AKYPISMVFYMGIRELPNLVPLLRQ-SHPGDLPIAVVYNAGYPdKEKVVKG 260
WP_013776789 130 RvSQTLIITRAS-ASVPMEGSiKDYAPF-LNKGASMVIYTGVHIIDKVVEELEEgGLSKDSPIAVVYKATWKgEEKIIKG 207
WP_014126992 130 KlIQTVVITRAS-ARVEMRGSlKEAAKFaATNGAVLAIYTGVHVIDKVVKELVDgGLPPDTPAAVVYKATWP-DQKVVRG 207
WP_089609838 130 GlPNTAICTTLR-DRE--DGE-EYFNLV-AALGASLAIFMSVELLDRVIHVLKK-YYPMTTPVVVICRATWP-EQQIAQG 202
WP_126449743 130 KiSQTVIITRAS-VAVPMEGSlRDFAPL-VNKGACLAIYTGIHVVEKVVRELREaGLADDTPVAIVYKATWP-EQLSFKC 206
WP_013706202 262 TMKNIREKIAAQKEEFMGLIIVGRCLDGAr---fPRSVLNLPERSSGEKP 308
WP_011007206 208 TLRDIAEKVKAERIVRDAVIIVGESVQPPe---iPRSAVYNPDHAHSYRP 254
WP_052846661 208 ELRDIAEKVKKEKITRDAVIIVGKIVRPEkykglVRSSTYDPKHYTSFRT 257
WP_011277312 208 TVGDIAQKVKAEKLTKDSMIIVGKVADPNrykdqIRSSVYDPSHAHSFRP 257
WP_013337006 207 TLSDIAEKVKRARITKDSVIIVGKAADPSildtpVRSSVYDPRHTHSFRP 256
WP_013706566 261 TLDTILEQVAGEKEKWMGLIIVGRCLEGKp---yRTRVENLVGYQDVKKS 307
WP_013776789 208 TLKDIAEKVKKEKITRDAVIVVGKILTPEky--eFKSSAYDENHYTGFRV 255
WP_014126992 208 TLSDIARKVREERITRDAVILVGESVAPRe---vPRSSVYDPRHTHSYRP 254
WP_089609838 203 NLLTISDLVSEQKI-TDGLILVGEFIDKE------YDYVLEKEFTERKKK 245
WP_126449743 207 RLSELVNQVRKRKISKDSIILVGKVVEPEkykgeVRSSVYDPSHAHTFRP 256
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