1VKW


Conserved Protein Domain Family
TM1586_NiRdase

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pfam14512: TM1586_NiRdase 
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Putative TM nitroreductase
Compared with the more traditional NADH oxidase/flavin reductase family, this family is a duplication, consisting of two similar domains arranged as the subunits of the dimeric NADH oxidase/flavin reductase with one conserved active site.
Statistics
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PSSM-Id: 405236
Aligned: 25 rows
Threshold Bit Score: 168.625
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1VKW_A          14 NIFEAIENRHSVRDFLERKXPERVKDDIENLLVKFI----TKKLDWKI-N------------LSSFPSYIYAKAEKh-fD 75  Thermotoga ma...
WP_015924241     5 ELYKTIFTRRSIRKYDMTPLPEQKLQEIKNFADNTKklvpGIKCEICFlDkenv----knifPIKAPHYISIYSEKk-eG 79  Ruminiclostri...
CDG64434         3 DLYPQMFKRKSIRDYYLEPLEEDMLQRIREQINKLEplygDIGVDLKImShdkv----nprmMKKAPYYLAAFSEDr-dG 77 
WP_012201259     2 NLYEAMFVRKSVRNYDMEALEEKLLENITSYIEQLKpyksSIEYEMIIvDntkeeekfkglfHVKAPYYLLISSELk-qD 80  Lachnoclostri...
jgi:Closa_1595   2 NLYQMIFKRRSIRKFKKEQVPEQLLKDILYFGENIPrlhgEILFKMEIsEnlddhlpvkglwKVEAPYYLTFYSEEk-eG 80 
CBL41289         2 SIYEAIFNRYSVREYRMEKIEPERLEALKRYLKTVAlldeEKPVEFEIvDntdkklkvhglwKTEAPYYLAVYCGDd-rL 80 
WP_118556176     2 NLYEAIGCRHSVRKYTDREVTEKLRGQILSYFDKTSrlndRIRVEAVIfDntkkkadvhglwKVDAPYYLAIYSDQe-eG 80  Clostridium
CCZ35191         2 NLFEAIFVRKSVRSYTNEALAPQMLEDILTQFEEIKglfgGIETELAIfDnregqykmlsmlGVKAPYYLILYSEEk-dR 80 
CDC47255         2 NLYEAIFLRKSVRSYEMETVSSELLQEIRDFYSQIEglnpGIRTDISIiDntdgknkimhlfGVKAPYYLVFYSEEk-dL 80 
WP_014730968     6 EIKKAIGLRVTQRKFQERQLSPEQKKEVNDALRDIVpinsESVLHWYFsPe-----------FPSGSGIVLAKMSDfstP 74  Mesotoga prima
1VKW_A          76 ELVEYGFQGEQIVLFLTAQGFGTCWXARSPHP-----------DVPYIIVFGYPRTRN----Ft--------RKRRPITS 132 Thermotoga ma...
WP_015924241    80 YLMNVGFMLQQVDLFLSANNLVSCWLGIAKPSkevpt-snndmEFVIMLAFGNTHEKL----Hrad---tseFKRKGISE 151 Ruminiclostri...
CDG64434        78 HQTNIGFMLQQMDLFFSANGLGSCWQGFPQPKkqfle--nsdkKFVIFIAFGKPKVQL----Hrts---tfeFNRKPLSK 148
WP_012201259    81 YLTNAGFLMQQMILYLTARGVATCYQGG--IKpnselkaklkyDYVIAIAFGRSEKTI----Yrap----ekAKRLSEDS 150 Lachnoclostri...
jgi:Closa_1595  81 YLVNAGYIMEHVLLYMTGKGLGTCYLGSTKVLepas----agmKQVIVVAFGYPKTLL----Yrdp----atAKRLPLKE 148
CBL41289        81 SMRNAGYAAEQAVLYLTSKELGTCYLGATKAGedkk----dglKRFLVIAFGKASAKP----Frds----smAHRNSLAA 148
WP_118556176    81 CERNAGYLMEQMVLYMTAKGIGTCYLGSVQPAqkvr----ggkRCLMMVAFGYPEGKL----Yres----plAKRLPLNE 148 Clostridium
CCZ35191        81 ALMNAGYLMEQLSLYLCTRGLGSCFVGNPILRkkyvr--rdnkKIMAVLAFGKARGSW----Vrkp----aeAKRLSLSE 150
CDC47255        81 AQMNAGYIMEQLGLFLCTRGLGTCFLGN--VKprfgnphkgnlKFVITMAFGKAKGSY----Trka----veASRMELKD 150
WP_014730968    75 SLVKYGFEGEQIVLNLTLKGFSTSWARl--------------pNYLSMIVVGFAADGSgdivErasrflyreANRKPLKE 140 Mesotoga prima
1VKW_A         133 FLENDleELPPEIVKIVEXTILAPSALNRQPWKIK-YTgGEL--------------CiSSERPVDLGIALSHAYLTA 194 Thermotoga marit...
WP_015924241   152 ITs------iTGADELLEAARLAPSASNSQPWYFS-GDqNEIiisrekl-sflkapIfNRINQIDMGIALCHLWLSI 220 Ruminiclostridiu...
CDG64434       149 ITd---iK-NEDLMEILEAARLAPSAINTQPWYFK-GDnQIIhaycsqp-nilkalVlNKYVKIDMGIVLCHIKLAA 219
WP_012201259   151 LIVYKedV-SENMKVIMQAAILSPSSMNNQPWRFV-VYrNRIhvfckk--arflksViSDMKLIDVGIVLSDIVQAA 223 Lachnoclostridiu...
jgi:Closa_1595 149 LCVFKeeA-GESMKNILRAVRLAPSAMNTQPWRFI-VYhDRIyifscr--eflpspTlVSMREIGTGIMLSHLTIAA 221
CBL41289       149 LCAFKdeP-GEQVKSILRAARLAPSSFNSQPWRFV-VYsDRLyifmkka-apfsgkGaKAFKEFNMGIMLSHIMLAA 222
WP_118556176   149 LCIFKeeA-GEQMKTILRAARLAPSAMNTQPWRFI-VYsDRIyvfalk--trfpgkSfHAMREFSIGIMLSHIMLAA 221 Clostridium
CCZ35191       151 VCVYKetP-RQWMNQLLDAARMAPSSMNSQPWRFV-VFdSRIhifsk----khasdRlGKWDELNFGIMFSHMMVVA 221
CDC47255       151 LCVYKevP-RQWMKQLLEAARLAPSSFNSQPWRFV-VYdNRIhvfak----khnmnHlGRYEEMNFGIMFSHLMVVA 221
WP_014730968   141 VVYGKedYIDEKMKDIIDAGRMAPSSFNRQPWKFEvLGeNEIaihgwkkipliyeeViA----IDLGVVLSHMYLMA 213 Mesotoga prima
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