Conserved Protein Domain Family
Leg1

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pfam05612: Leg1 
Leg1
Protein liver-enriched gene 1 (Leg1) has been suggested to function as a novel secreted regulator for the liver development.
Statistics
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PSSM-Id: 428543
Aligned: 5 rows
Threshold Bit Score: 427.382
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4QRF7        29 GLPIqwrKAPSDLSHLPISntgvqvNPWVYSQRMTMLKMVINATNayMSSMGPGEQENPLWSLPLQLGWKLKSGRLADPT 108 zebrafish
Q54KF5        26 KKEI---KISNDKINLPTY------NPWIFQDRFNLYSILINSTN--IPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQ 94  Dictyostelium d...
XP_007259743  26 GLPIlwgSAPSMLSELPQAdgvvkpDPFDYLQRMAMYRLMINATDpyMSSMGPAANENPLWGLPLQLGWKLRSGRLVDPT 105
XP_003971659  27 GAPIlwaQTFSQLSELPMLngtvtpNPWNYLHRMSLIRLTIAATDtnMGFIGSSGTASPLWGLPLQLAWMLTSGRLADPT 106
XP_003440678  27 GAPIlwaQTASQVTELPMHdgillpDPWNYLHRMSLYRLMIAATDpfMGSMGTNATDSPLWGLPLQLGWMLTSGRLADPT 106
Q4QRF7       109 pdSSstcgseasdpvcISPLSFFGCVNYYLSVLPFLAAVETGVVSsgghqmLIQVPAEVAQDYCSSYSDCSTkhpNTMAK 188 zebrafish
Q54KF5        95 --GH------------VNTKSWWGDMNYYLSIIPYLSAMKMGLVP------VVEIVSINDQRFCSTYEDCDQ---EVLNN 151 Dictyostelium d...
XP_007259743 106 --GVstcgqesfspvcIATSSWWGCVNYHLSVLPFLAAVEAGVVGdgqaqvEIQVPAEVAAVYCSS--NCSSthpDAMNK 181
XP_003971659 107 --GAstcgvqtgdpmcISTQSWWGCVNYFSSVLPFLSAVQQGFMGaev-qvQLLLPEG--EDFCTTYADCAArfpDAMSK 181
XP_003440678 107 --GAttcgle-aeplcISTQSWWACVNYFASVLPFLSAAQQGFMGaga-qvQMQVPAGV-QDYCTTYADCKAkypDAMSK 181
Q4QRF7       189 WHLFFQSLRQVSQSKESDFNKKdsILGLMWAAEEESIQTASGACTERQKLYSSPEVSFQQSSVNLGAFISAAHYHASIER 268 zebrafish
Q54KF5       152 WDNFFQQIINIRNNGSEGDDQQ--LLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYST 229 Dictyostelium d...
XP_007259743 182 WLTFFQSLKTISASEVSDEEKRdqILGLMWSAQLASLDTAASTCADKKALYSGKEVAYSESWLSSAQYVGAAHFSSGLDR 261
XP_003971659 182 WDAFYQGLKALVDSPLPEGVKKdtLLGLYWAAQMAT-SAGSSACSTRQRHYSSAETSFANSWVSTAEYVAAAHFQSSLEN 260
XP_003440678 182 WDAFFQGLKTTSESLLPDDVKKdtILGVYWDAQMAS-TYASAACNARQSHYSSVEVSFAQSWLNSAEYVAAARFQANMEK 260
Q4QRF7       269 SGKFMSHLPSRVLQEADSPP-NIADLSTEENHALYMlswMNSINQLLGGSLVdlWRKAMC---SAQAREKGQAFLD---D 341 zebrafish
Q54KF5       230 VYHLGQQLPPIMLNSNDTHPsSIESFTKEQRNVVLT---MYEINDLSSNNLV--WNSFMYllkKMTKNEICRNLINneiN 304 Dictyostelium d...
XP_007259743 262 SVQFMRPLPSRVLLQTDIPP-NIADLSTEENHTLYIfgwMTTANKLLGGSLTlmWQKAMC---TSAAREKGRTLLN---D 334
XP_003971659 261 SAMFIKNLPGRVLKSDDRAP-NIADLSQEENHTLSIfswMSTINNILGGSLVrmWKSAMC---SVTTREKGREMLG---Q 333
XP_003440678 261 ALLFLSPLPSRILQEGDSAP-NIVGLTAEENHTLYIfswMKTIDSLLGGTLLrlWKGAMC---SVNTRQKGAQVLE---Q 333
Q4QRF7       342 LILDPKFPGssLWSIICVMST 362 zebrafish
Q54KF5       305 IFLNSPVPT--IIEILFDILT 323 Dictyostelium discoideum
XP_007259743 335 LLFNPQFATssMLSILSEMIT 355
XP_003971659 334 LLLNPSFATssLLTIITETSR 354
XP_003440678 334 LLLNPSFATstFLSIITEMTT 354
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