Conserved Protein Domain Family
pyrE_Therm
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TIGR01367: pyrE_Therm 
orotate phosphoribosyltransferase, Thermus family
This model represents a distinct clade of orotate phosphoribosyltransferases. Members include the experimentally determined example from Thermus aquaticus and additional examples from Caulobacter crescentus, Helicobacter pylori, Mesorhizobium loti, and related species. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis]
Links
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Statistics
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PSSM-Id: 273579
Aligned: 4 rows
Threshold Bit Score: 306.713
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9WYG6         1 MIKEILEKTGALMEGHFILSSGKHSSRYVQCARLFEFPEYGDVVGEELAKLLKKY--DVETVVGPAMGGVILSYVVARYL 78  Thermotoga mari...
Q9RX68         5 DVLDLYKQAGAFHEGRFLLASGRQSPYFMQSTTLLQHPRALMELGGLMSQKILDAglKPDFIVGPAMGGVTLAYEVARQL 84  Deinococcus rad...
WP_002851820   2 NLEQIYKDCGAYLEGHFLLSSGKHSQFYLQSAKVLEDPKLAAKLCDELAKIIASYkiEFDSICSPALGGILAGYELARAC 81  Campylobacter j...
WP_010919429   5 DVLDEFRAAGALREGHFVLSSGLHSPVFLQKNLVFMRPERCERLCKALAQKIIATvgQVDVAVSPAVGGIIPGYETARHL 84  Caulobacter vib...

Q9WYG6        79 K-----ARSLFAEREN-GVMKLRRGFFVKPGEKVAVVEDVVTTGGSVKEVIELLKEYGANVVCVGSIID----------- 141 Thermotoga mari...
Q9RX68        85 SetlpdVRAIFAEKDGsGGMKLREAFAVRPGETFVAVEDVLTTGGSLLRAVRAVEGQGGQCIGLCCIID----------- 153 Deinococcus rad...
WP_002851820  82 S-----KRFIFTERVN-KEMTLRRGFEVKKGEKFIICEDIITTGGSALESAKIIESLGGIVVGFAALANrgfcavenlks 155 Campylobacter j...
WP_010919429  85 N-----VPSIYVEREG-GGFKFRRGFHLEPGQKVVMVEDIVTTGLSSRECIQAIKDAGGDVVAAACIVD----------- 147 Caulobacter vib...

Q9WYG6       142 -RS-GGKVDFGVPFESLLKLDLPVYDPEDCPLCKQGIPAEKP 181 Thermotoga maritima MSB8
Q9RX68       154 -RRqQTGPLSGYPLMSLKELYFDTYASHEVPGWLAERPLQEI 194 Deinococcus radiodurans R1
WP_002851820 156 pRKdNAKLPENLPLFTLGNFEFEIYDETNCPLCKKGNKAIKP 197 Campylobacter jejuni
WP_010919429 148 -RS-GGKADVGVPLIALASLEVPAYPADALPPELAAIPIEDP 187 Caulobacter vibrioides
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