Conserved Protein Domain Family
cGAS

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NF041078: cGAS 
CBASS cGAMP synthase
Statistics
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PSSM-Id: 469005
Aligned: 61 rows
Threshold Bit Score: 264.519
Created: 24-Apr-2023
Updated: 4-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_067059564   3 DISTNNLHRVFKNNnDGFFHKLIPSMEQLDAFKYCKDKVQEKLESDLKE---IYGVKPKFRLQGSWAYGTCNVPALATQE 79  Moraxella atlantae
WP_073360593   1 MANCNELF-------KTFNSTIRLNEESREILKSVRNSLREKMNSRFKQikdIDNHTLEFQSQGSFIMDTIIKPKDDD-- 71  Flavobacterium ...
WP_109681875   1 MADLNETF-------VEFNDIIKLSTTRKDELRKSRNAVREDIKDYFNKnrdL--HTVKFKGQGSFSMNTSILPLS--GE 69  Xanthomarina sp...
WP_089048351   1 MADLHETF-------TEFNGIIALSSAKKNELRTSRNAIRKDIKSYFELkrkE--HTVKFKGQGSFSMNTTILPLS--GE 69  Flavobacterium ...
WP_103725691   1 MADLNETF-------VSFNGNIKLSEKRKKELRTSRNAVREDIRKYFDDnrdK--HTVKFKGQGSFSMNTSILPLS--GE 69  Flavobacterium ...
WP_100612827   1 MADLHETF-------TEFNRIIALSSTKKNELRTSRNSIRKDIETYFDKnrdK--HTVKFKGQGSFAMNTTILPIS--GE 69  Confluentibacte...
WP_123859672   1 MADLHSTF-------IDFNDCIKLNATKKNQLKTSRNSVRTDIRTYFSNnrdK--HTVSFKGQGSYMMNTTIEPLSKE-- 69  Chryseobacteriu...
WP_091257192   1 MADLHSTF-------TEFDDIIKLSSKKKETLRTSRNSIRTDIEKYFEEkreK--HTVSFKGQGSFMMHTTIQPLS--KE 69  Flavobacterium ...
WP_090605468   1 MADLHSTF-------LEFDDIIKLSSDKKKSLRTSRNSIREDIRDYFDEnrdK--HTVSFKGQGSFLMNTTIEPLSGE-- 69  Parapedobacter ...
WP_010274519   1 MSNCHDLFIKFHDDe------IYLKSDKKESLRTSRNALRDKIKKYFSEeldV--KKPKFYGQGSYMMNTTVTPID--GE 70  Paenibacillus s...
WP_067059564  80 MDFDYGCYLPNVCFv-DDEKTEGEKILRYVEKSLQVV-CDEQDWTLDTSNASCLRITgFLPQ-AHFDVPLYAVPDDMfad 156 Moraxella atlantae
WP_073360593  72 YDLDDGVYFIGSLTqeKRP--TTQQFHDAVIIAV----GTDENYATITDKETCVRVS-YEKEkFHIDLPIYYAn------ 138 Flavobacterium ...
WP_109681875  70 YDVDDGVYIFGKKe--DRP--TTSTAHSWIVKAVENR-TDQN----TIDKNTCVRVQ-YAKK-YHIDLPIYYKTTDSnhe 138 Xanthomarina sp...
WP_089048351  70 YDVDDGVYIFGT----EEDKPTPETAHSWIVKAVENR-TDQN----TIDKNTCVRVQ-YAKK-YHVDLPIYYKITNNene 138 Flavobacterium ...
WP_103725691  70 YDVDDGVYIFGKEE--DRP--TPSQAHGWILKAVENR-TNQN----SIDKNTCVRVQ-YAAQ-YHIDLPIYYKTTDNdne 138 Flavobacterium ...
WP_100612827  70 YDVDDGVYIFGK----EEDKPTPNTAHNWIFKAVENR-TNQE----TIDKNTCVRVQ-YAKS-YHVDLPIYYKTTDTdne 138 Confluentibacte...
WP_123859672  70 FDIDDGVYIFGK----EEDKPSVQTAHNWIYDAIKNR-TSSE----PLDKNTCVRVI-YKND-YHVDLPIYYVFDRKddq 138 Chryseobacteriu...
WP_091257192  70 YDVDDGVYIFGK----EEDRPTPQTAHNWIYDAVKNR-TSSE----SLDKNTCIRVI-YKSD-YHVDLPIYYKVEKSdne 138 Flavobacterium ...
WP_090605468  70 YDVDDGVYIFGK----EEDKPTVQTAHNWIYNAVKDR-TSSE----PLDKNTCVRVI-YKKD-YHVDLPIYYKTDKSddq 138 Parapedobacter ...
WP_010274519  71 YDIDDGIYLEHLKNsdEGDWPTPSTVHSWIVKATKNHtSEEP-----VDKNTCVRVI-YKAN-YHVDLPIYIKKDDQ--- 140 Paenibacillus s...
WP_067059564 157 lqdvqirtqksetianesmgldsailsfdfsekngdtrpdslsayfgesqfsneiafttlsnearqgryelgldsinekn 236 Moraxella atlantae
WP_073360593     --------------------------------------------------------------------------------     Flavobacterium ...
WP_109681875 139 ff------------------------------------------------------------------------------ 140 Xanthomarina sp...
WP_089048351 139 df------------------------------------------------------------------------------ 140 Flavobacterium ...
WP_103725691 139 yf------------------------------------------------------------------------------ 140 Flavobacterium ...
WP_100612827 139 nf------------------------------------------------------------------------------ 140 Confluentibacte...
WP_123859672 139 f------------------------------------------------------------------------------- 139 Chryseobacteriu...
WP_091257192 139 n------------------------------------------------------------------------------- 139 Flavobacterium ...
WP_090605468 139 f------------------------------------------------------------------------------- 139 Parapedobacter ...
WP_010274519     --------------------------------------------------------------------------------     Paenibacillus s...
WP_067059564 237 sipktvkkannqkiQNIRLIKRDEDWKTSDCEKVREWF--------------------------VGTCDKYpneGQQLRA 290 Moraxella atlantae
WP_073360593 139 -------------kINPELAHTKEDWILSNPIKFIAWFekiaessfreelileknlfseeyktwLDDIRKK---DVQLRR 202 Flavobacterium ...
WP_109681875 141 ----------ydseDVPELAHKGEGWVESDPYAFKLWF--------------------------EKAAKDK----DQLKR 180 Xanthomarina sp...
WP_089048351 141 ----------ydndDIPELAHKSKGWIQSDPYAFKKWF--------------------------DDKSKDK----SQLKR 180 Flavobacterium ...
WP_103725691 141 ----------fdssDVPELAHKDKGWIPSDPYAFRLWF--------------------------EEKAKGK----EQLKR 180 Flavobacterium ...
WP_100612827 141 ----------fdseDIPELAHKTKGWIESDPYAFKKWF--------------------------DEKAKDK----NQLKR 180 Confluentibacte...
WP_123859672 140 ----------tfldEPPLLAHKSKGWIKSDPYKFKIWF--------------------------DQQARDK----PQLKR 179 Chryseobacteriu...
WP_091257192 140 ----------tlddEVPEIAHLSKGWIQSDPYAFKKWF--------------------------DDQSKGK----SQLKR 179 Flavobacterium ...
WP_090605468 140 ----------ilddEVPLLAHKSKGWVESDPYAFKKWF--------------------------DDQAKSR----PQLKR 179 Parapedobacter ...
WP_010274519 141 ---------------SPKLAHKSKGWITSDPKALTDWF--------------------------KGEVQIK---GDQLKR 176 Paenibacillus s...
WP_067059564 291 IVRYVKSWRDFLTPQfKk--APSSIALMVLTTQSYEHL-QQRDDKALNEVIKNLPNGLV---------KSIKCKDIVGHe 358 Moraxella atlantae
WP_073360593 203 IVRYLKAWGDDLRGe-----MPPGIVMTILAAENYVKN--DRDDIALKETLIKIRQYLKsn------nCKCLRPTVPVG- 268 Flavobacterium ...
WP_109681875 181 IVRYLKAWTDNKHHl----nLPSGIVFTILAVNNYVSN--SSDDKAFLETLEAIQKSIDdtrs-ywasYVCKRPTINTT- 252 Xanthomarina sp...
WP_089048351 181 IVRYLKAWTDNKSRl----kLPSGMIFTILAVNNYQPN--DKDDVAFLDTLEKIQKSIDdtrftwtgvYECKRPTVDDT- 253 Flavobacterium ...
WP_103725691 181 IVRYLKAWTDNKHHl----nLPSGMIFTILAVNNYVSK--DRDDEAFLETLKSIQLAIDsskn-fwarYECFRPTVDTT- 252 Flavobacterium ...
WP_100612827 181 IVRYLKAWTDNKSHl----nLPSGMVFTILAVNNYVSK--DRDDESFLETLQGIQKSIDdtrh-iwakYECYRPTVDTL- 252 Confluentibacte...
WP_123859672 180 IVRYLKAWSNKKQQDnNslkFPSGMIFTILASENYYAD--TRDDISLLETLKAIQKKIDnnkf--ftsYSCYRPTTDTS- 254 Chryseobacteriu...
WP_091257192 180 IVRYLKAWSDKKQNDnAkliFPSGMIFTILASNYYVEN--DRDDLSLLETLKKIQSNIDdirf-efinYECYRPTVDKN- 255 Flavobacterium ...
WP_090605468 180 IVRYLKAWSNKKQEDnSllrFPSGMVFTILASENYVSN--GRDDKALLGTLKAIQQSIDdikf-lsanYSCYRPTVDMY- 255 Parapedobacter ...
WP_010274519 177 LVRYLKAWKDYKESDtK---FPSGMILTILAANHFVSDyPDEDDAALVATAKEIHNTLSe-------sFSLVRP-VVPG- 244 Paenibacillus s...
WP_067059564 359 sEDFNN-LN-EEERERAKSLATQFSQVLDECLFkHT--SAIDCL-EDLKTQFGYRIP 410 Moraxella atlantae
WP_073360593 269 -EDLFKnYS-QTKKQYFLDRLDTFIESAEQAVN-HP--NQKDACyKW-QKHLGPRFP 319 Flavobacterium fontis
WP_109681875 253 -ENLLDkYSsETRKKNFLDALDGLINSGKQAIE-LK--SKKDACaKW-QKHLGDRFP 304 Xanthomarina spongicola
WP_089048351 254 -ENLLEkYSsETSKKNFLDALNSLIDSGRQAIN-LK--SKKDACaKW-QKHLGDRFP 305 Flavobacterium hercynium
WP_103725691 253 -ENLLVkYSsETKKKNFLDALDSLITSGNQAIE-AK--SKKDACaKW-QKHLGDRFP 304 Flavobacterium croceum
WP_100612827 253 -ENLLDkYSsETRKKDFLDALNSLITSGKQAVE-VK--SKKDACaKW-QKHIGDRFP 304 Confluentibacter lentus
WP_123859672 255 -ENLLDkYSaSTTKSNFLDALDSFIKSGDQAIE-LE--SKKDACsKW-QKHLGDRFP 306 Chryseobacterium nakagawai
WP_091257192 256 -ENLLDkYSsETTKNNFLNALDSFINSGDQAIE-LE--SKKDACsKW-QKHLGDRFP 307 Flavobacterium omnivorum
WP_090605468 256 -ENLLDkYSsQGTKSSFLNALDSFIKSGEQAVE-LE--SKKDACaKW-QKHLGDRFP 307 Parapedobacter koreensis
WP_010274519 245 -EELFDnWS-ETRRSNFLNKLEDLIKKGGEQLL-HDlfDSATLR-KNFHSAFAAYFL 297 Paenibacillus senegalensis
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