1O70,5YJG,5YJG,1O70,1NYO,2MXA,5YJG


Conserved Protein Domain Family
Fasciclin

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pfam02469: Fasciclin 
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Fasciclin domain
This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.
Statistics
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PSSM-Id: 396845
Aligned: 121 rows
Threshold Bit Score: 62.6559
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1O70_A        169 PMMSDTYKMGKFSh--FN-DQLnNTQRRFTYFVPRDKGW---------QKTeldypSAHKKLFMAD-FSYHSKSILERHL 235  fruit fly
Q8WWQ8       1148 PDYSIFRGYIIQYn--LA-NAI-EAADAYTVFAPNNNAIe--------NYI--------REKKVLS----LEEDVLRYHV 1203 human
2_pfamImport    1 LNLTSAAGALRRAd--LS-TRLdRL-RDVTMFIPNNDAF---------NMV-----GSSFEDSNM--SASQLSQVLQYHI 60  
P90848        351 DKTTTLMRYINTIg-qIVrNYFsATGGLVTFFAPWNEAF---------DRI-----PEQIERRLLR-DRIWLEQILKLHI 414  Caenorhabditi...
Q7QI08        347 TLWSKFRDLIEDYapeFL-NVL-RGMSQMTLFVPQDEAV---------AQM--------MQTNFMS-NRKKLLEVLMMHV 406  Anopheles gam...
1O70_A         23 ALRKFYEVIMDNGg-aVL-DDI-NSLTEVTILAPSNEAW-----------------NSSNINNVLR-DRNKMRQILNMHI 81   fruit fly
O11780        113 VGSTTTQLYTDRTe-kLR-PEM-EGPGSFTIFAPSNEAW---------ASL-----PAEVLDSLVSnVNIELLNALRYHM 175  pig
Q7T1R2        107 VEATTTKMYSERAk--LQ-EEI-EGPGSFTFFAPSNEAW---------APL-----PTEILDALVSnVNIELLNALHYHM 168  zebrafish
O61457        583 KNLTIFQRLLEASg--YD-DQF-DDLDNVTIFAPTDKALqnt----ewARM-----LKEQPELLN--HNLDLLEFLNYHV 647  fruit fly
Q7PHD5        405 HNLTVFKQLISDAg--LE-EEF-DGMSNRTFFIPTDQAFeqtetgrywIRQ-----LKEHPESLR--GNAALKEFLEYHV 473  Anopheles gam...
1O70_A        236 AIS-DKeyTMKDLVKFs----QESGSvILPTfrdslSIRVEEE---------AG---------RYVIIWnykkINVYrpD 292  fruit fly
Q8WWQ8       1204 VLEeKL--LKNDLHNG-----MHRETmLGFSy----FLSFFLH---------ND---------QLYVNE----APINytN 1250 human
2_pfamImport   61 VQG-SRp-FYTSALGN-----SSLTT-LNGA-----RLTFTNT---------SN---------GLFVNS----AKIIspN 105 
P90848        415 VPAkEL--TSDEITNE-----TIVNTvDNMR-----QLYFIKGew-----ptNNv--------TYYVIGggikTAIMmdN 469  Caenorhabditi...
Q7QI08        407 VPD-AI--TIDKIKRNnqnhiYQIPTmNSRR-----FLYFNLNenr---tthDK---------SVTVEGggvnASLVlgD 466  Anopheles gam...
1O70_A         82 IKD-RL--NVDKIRQKnanliAQVPTvNNNT-----FLYFNVRge-----gsDT---------VITVEGggvnATVIqaD 139  fruit fly
O11780        176 VDR-RV--LTDELKHG-----MALTSmYQNS-----NIQIHHYp--------NG---------IVTVNC----ARLLkaD 221  pig
Q7T1R2        169 INK-RL--TSEDLKHG-----SSFSSmHQDF-----DVHIHHYs--------NG---------IVTVNC----ARLVktD 214  zebrafish
O61457        648 VKP-MI--KTCDLSEKs------LPT-VAGS-----SVRLNLY---------SThalfsdvmnRATVNC----ARLVhfD 699  fruit fly
Q7PHD5        474 AEP-LI--KTCGLEE------TTIPT-KAGQ-----NVRVNLYttnpvfttvMN---------RATVNC----ARLVrfD 525  Anopheles gam...
1O70_A        293 VECTNGIIHVIDYPL-LE 309  fruit fly
Q8WWQ8       1251 VATDKGVIHGLGKVL-EI 1267 human
2_pfamImport  106 VLTNNGVIHILDNVL-NP 122 
P90848        470 VAATNGIVHYIERVLgVP 487  Caenorhabditis elegans
Q7QI08        467 IATKDGYIHIIDRML-GV 483  Anopheles gambiae str. PEST
1O70_A        140 VAQTNGYVHIIDHVLgVP 157  fruit fly
O11780        222 HHATNGVVHLIDKVI-ST 238  pig
Q7T1R2        215 QHATNGIVHVVDRVI-TA 231  zebrafish
O61457        700 DESCGSVLHQVDRAL-AP 716  fruit fly
Q7PHD5        526 EETCGSVVHEIDKVLdVP 543  Anopheles gambiae str. PEST
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