Conserved Protein Domain Family
RPW8
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pfam05659: RPW8 
Arabidopsis broad-spectrum mildew resistance protein RPW8
This family consists of several broad-spectrum mildew resistance proteins from Arabidopsis thaliana. Plant disease resistance (R) genes control the recognition of specific pathogens and activate subsequent defense responses. The Arabidopsis thaliana locus Resistance To Powdery Mildew 8 (RPW8) contains two naturally polymorphic, dominant R genes, RPW8.1 and RPW8.2, which individually control resistance to a broad range of powdery mildew pathogens. They induce localized, salicylic acid-dependent defenses similar to those induced by R genes that control specific resistance. Apparently, broad-spectrum resistance mediated by RPW8 uses the same mechanisms as specific resistance.
Links
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Statistics
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PSSM-Id: 398988
Aligned: 13 rows
Threshold Bit Score: 150.136
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EEF40015        3 ADL-----VGGAVLGAILGELLEAVLRAKNRTFMFKSILKRMECTLETVTPIVKEIEELNKVL-DRRNeEMGIIMKEIRK 76  
EEF40016        6 ASA-----AAGAGLELAFGSLLRIILEVRRKNVMFASTLQILIDTMEAIRPSIKRIDSFNTDF-DRPD-EIKGLRDLIRK 78  
XP_002265449    3 lEL-----VGGAALGAVFEKLFAAVVDASNKATQFESSLKKLEETLKSINPSILEMKKLNDEL-DRPKeEMEKLIQILKD 76  
XP_010316804    3 GNL-----IGGAAIGQAFRMLSESITEAGKTSVCFDSNFRRLNSTLLSIKPVLEDIERLNKAL-EGREsETELFNKRLEE 76  
Q9SCS6          4 AELaviktVGGPLIAAALGVGAQVIYDGFRKGKDT-SIINRLGRTMESISPVRDRIGKLSNVEgKPFReVHESLTRLLED 82   thale cress
Q9SCS7          4 SEI-----MAGAALGLALQVLHDAIKKAKDRSLTTRCILDRLDATIFRITPLVTQVDKLSEEVeDSPRkVIEDLKHLLEK 78   thale cress
3_pfamImport    1 GEV-----LVGAALGITLQVLHEAIIKAKHRSLTTKCILDRLDATISRITPLVVHVDKISKRVeDSERkVIEELKRLLEK 75  
2_pfamImport    1 IEL-----MAGAALGLALQVVHEAIKKAIERSLSTRYILYRLEDTISRITTFVAQVDKLSEEVeDSPRkIIEDLKNHLDN 75  
XP_002876033    4 AEI-----IAGAALGLALQILHEAIQRAKDRSLTTSCILDRLDSTILRISPLIAKVEKLGKESdESMRkVIKDLKHLLEK 78  
XP_002876032    4 VEL-----FAGAALGFALQLLHEAIIRAKERSLITRCILDRLDATIYKITPFVNKIDTCTEEVdEPLRkVIEELKCLLEK 78  
XP_006852958    1 mDL-----VSGAIIGAIAGEILKALLDATNIVYECKSQCEKLKSTLQHIVPKLEDIEQLRLQLtDCEPaDFKELKSRLES 75  
1_pfamImport    1 --------VGGAFLGAPVSEILKLVIEEAKKVKDFKPLSQDLASTMERLVPIFKEIDSMQ----QRCNgELIVLIKTLER 68  
Q84WJ0          7 ASL-----VGGAALGAPLSEIFKLVIEEAKKVKDFKPLSQDLASTMERLVPIFNEIDMMQQGS-NRGTsELKVLTETMER 80   thale cress

EEF40015       77 GKKLVLECSGMQwYYACWRTPKYAGKLIKLEKSLKLFFQIVMQAQRARDGKEALLE--MKDLRMDLKR 142 
EEF40016       79 GEDLVIKCSKVH-KYNYVKKPYYTKKLIKLDESIRRYISTILPLYQTSDIKETLYE--MRVLSTQIRN 143 
XP_002265449   77 GEKLIHKCSKVS-CCSCFKKWRYANKIEALEDSLLNFFQVELQAQLGRNNVEILVM--LKSNRFSlsn 141 
XP_010316804   77 GEKLVRKSAKIK-RYNVCKRWYYSKKLADLEKSTMNFFEVHGLMQSCRDRKKILVA--LKEEGEKLDE 141 
Q9SCS6         83 AKSIIEKYWKLRwSRHVCRKYRYIKKLESIELELVR-VAREIQVHQWTDIKEMKAI--QVHQWTDIKE 147  thale cress
Q9SCS7         79 AVSLVEAYAELR-RRNLLKKFRYKRRIKELEASLRWMVDVDVQVNQWVDIKELMAK--MSEMNTKLDE 143  thale cress
3_pfamImport   76 AVSLVEAYAELR-RRNLHKKHWCKSRIKELEASLRWMVDVDVQVNQWLDIKELVTK--MSEMNTKLDK 140 
2_pfamImport   76 AASLLKAYAELR-RRNLIKKYRCRRSIKELEASLRCMINVDVQVNHW-DIKKLMAT--MSETNTKLQ- 138 
XP_002876033   79 AVVLVEAYAELK-RRNLVGKYRYKRRIKELEGSLKWMVDVDVKVNQWADIKDLMAK--MSEMNTKLDK 143 
XP_002876032   79 AIRLVEAYAELK-RRNLLRKYRYKRRIKELDASLRWMVDVDVQVNQWLDIRKLMGK--MSEMNTKLDE 143 
XP_006852958   76 GKVLVYKCMKLR-FWKVHKKYSYGKKLIELDEYLVRFFDLNLAADTNLDTKQLRIE--FKEMRRLLDg 140 
1_pfamImport   69 AEKMVSKCSGVK-WYSISKKALYTREIKEINQEFLKFCQIELQLIQHRNQLQSMQS--MASVTMNIDL 133 
Q84WJ0         81 AGEMVHKCSRIQ-WYSIAKKALYTREIKAINQDFLKFCQIELQLIQHRNQLQYMRSmgMASVSTKADL 147  thale cress
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