5OCU,2WBE,5MLV,3NWN,1SDM,1F9U,1CZ7,5WDE,5LT3,6ZPH,1T5C,1VFZ


Conserved Protein Domain Family
Kinesin

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pfam00225: Kinesin 
Kinesin motor domain
Statistics
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PSSM-Id: 459720
Aligned: 69 rows
Threshold Bit Score: 308.733
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5OCU_K   20 RVRPENTKEKAAGFHKVVHVVdkhilvfdpkqeevsffHGKKTTNQNVIKKQNKDLKFVFDAVFDETST--QSEVFEHTT 97   human
1SDM_A   12 RLRPLCEKEIIAKERNAIRSV--------------------DEFTVEHLWKDDKAKQHMYDRVFDGNAT--QDDVFEDT- 68   potato
O08672  415 RLRPAEGQPSSLVSVEPG------------------------QGGTITTCYRGRQHCFRLDWVFPQDASqeEVFRQLE-- 468  house mouse
P45962  251 RIRPQLASETDNQKPVVVIDE------------------MDNGVVHVSNTTGTRKTSAGADKVIPTDFS--QDQIFNEV- 309  Caenorhabditis elegans
Q9LX99  148 RARPLFEDEGPSVIEFPGDC--------------------TICVNTSDDTLSNPKKDFEFDRVYGPHVG--QAALFSDV- 204  thale cress
O95235   70 RVRPLLPSELERQEDQGCVRIenvetl------vlqapKDSFALKSNERGIGQATHRFTFSQIFGPEVGqaSFFNLTVK- 142  human
Q9PUU5   31 RVRPLGAEDEECCIEVISNTTi---------------qLHAPDGLKANRNGEFKETQYSFKKVFGIKTTqrELFEDVAK- 94   zebrafish
Q9VZF5   42 RVRPLQSDADLTSLRVKNSTTial------------npQDQLLQHHKPHNGAQREVQYIFKHVFQPDAT--QQDVYAAVA 107  fruit fly
Q9V877   93 RLRPVKDASKAYIVSEEANVL-----------------ITSCKVDSTSNNVNRMEKHFGFTSIFDSTVG--QRDIYDTC- 152  fruit fly
P32364   33 RAIPEKGLQNNESTFKIDPYEn---------------tVLFRTNNPLHETTKETHSTFQFDKVFDANAT--QEDVQKFLV 95   Saccharomyces cerev...
5OCU_K   98 KPILRSFLNGYNCTVLAYGATGAGKTHTMLGS--ADEPGVMYLTMLHLYKCMDEIKEE---------------------- 153  human
1SDM_A   69 KYLVQSAVDGYNVCIFAYGQTGSGKTFTIYGA--DSNPGLTPRAMSELFRIMKKDSNK---------------------- 124  potato
O08672  469 -PAVLSCLQGYSVCIFTYGQTGTGKTYSMEGp-pED-PGIAPRALQLLFREMGTgg------------------------ 521  house mouse
P45962  310 SPIITSCIDGYNVCIFAYGHTGSGKTYTMDGp--VTMPGINQRAIMQLFETAKERTGD---------------------- 365  Caenorhabditis elegans
Q9LX99  205 QPFVQSALDGSNVSILSYGQTNAGKTYTMEGS--NHDRGLYARCFEELFDLANSDSTSt--------------------- 261  thale cress
O95235  143 -EMVKDVLKGQNWLIYTYGVTNSGKTHTIQGtikDG--GILPRSLALIFNSLQGQLHPtpdlkpllsneviwldskqirq 219  human
Q9PUU5   95 -PLAQDLIHGKNGLLFTYGVTGSGKTHTMTGspgQG--GLLPRSLDMIFNSIGPYQAKryvfkpddkngmevqnqvdall 171  zebrafish
Q9VZF5  108 QPLVENLLKGRNSLLFTYGVTGSGKTYTMTGN--LRHRGIMPRCLDVLFRTISDYQAKkfvfkpdklngfeilseedall 185  fruit fly
Q9V877  153 --VGPKIMEEECVTIMTYGTSGSGKTYTLLGd--DVRAGIIPRALENIFTIYQDTVFRspklklingsivflqddaslke 228  fruit fly
P32364   96 HPIINDVLNGYNGTVITYGPSFSGKSYSLIGS--KESEGILPNICKTLFDTLEKNEETk--------------------- 152  Saccharomyces cerev...
5OCU_K  154 -----------------------------------------------------------------------------KIC 156  human
1SDM_A  125 -----------------------------------------------------------------------------FSF 127  potato
O08672  522 ----------------------------------------------------------------------------hH-- 523  house mouse
P45962  366 -----------------------------------------------------------------------------IKY 368  Caenorhabditis elegans
Q9LX99  262 -----------------------------------------------------------------------------SRF 264  thale cress
O95235  220 eemkklsllngglqeeelstslkrsvyiesrigtstsfdsgiaglssisqctsssqldetshrwaqpdtaplpvpanIRF 299  human
Q9PUU5  172 drqkrdsqts-----------------------------------vpktpntrrvdpefadmispeeackaegvdedSSY 216  zebrafish
Q9VZF5  186 erqhemnqrfa---------------------------------gsgrfafrhkdsdpeiasqasvepipllgldedNMY 232  fruit fly
Q9V877  229 lqirkkll----------------------------------------dlcpdisahhqrlkqvidgdhmfetkastDVS 268  fruit fly
P32364  153 ----------------------------------------------------------------------------gDSF 156  Saccharomyces cerev...
5OCU_K  157 STA-VSYLEVYNEQIRDLLVNSg-----------pLAVRE-DTQkG-VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPT 222  human
1SDM_A  128 SLK-AYMVELYQDTLVDLLLPKqak-------rlkLDIKK-DSK-GmVSVENVTVVSISTYEELKTIIQRGSEQRHTTGT 197  potato
O08672  524 HVT-LSMVEIYNEAVRDLLATGpper-------lvvrQGP-AGQ-GgIQVAGLTHWDVPNLETLHQMLSLGRSNRATAAT 593  house mouse
P45962  369 DIK-VAMMEIYNEKIRDLLNTSnt----------nLAIRQ-TEEgR-SSIPGLEEVSVNSAEEVTETLARGRKNKAVAAT 435  Caenorhabditis elegans
Q9LX99  265 SFS-LSVFEIYNEQIRDLLSETqs----------nLPNINmDLHeS---VIELGQEKVDNPLEFLGVLKSAFLNRGNYKS 330  thale cress
O95235  300 SIW-ISFFEIYNELLYDLLEPPsqqr-----krqtLRLCE-DQN-GnPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFAST 371  human
Q9PUU5  217 SVF-VSYIEIYNNYIYDLLEETpfdpik-pkppqsKILRE-DQN-HnMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANT 292  zebrafish
Q9VZF5  233 SVF-VTYIEIYNNSVYDLLEDSgiqk-----tlqsKIIRE-DANrH-MFVHGVTEVEVKTVEDALEVFQMGQKRKRMGHT 304  fruit fly
Q9V877  269 VLVwVSFVEIYNELVYDLLAIPpkqdklgevprknLKIVG---NkGhVFIKGLTSVFVTSSEEALRLLRLGQQRSTYAST 345  fruit fly
P32364  157 SVS-VLAFEIYMEKTYDLLVPLper--------kpLKLHR-SSSkMdLEIKDICPAHVGSYEDLRSYIQAVQNVGNRMAC 226  Saccharomyces cerev...
5OCU_K  223 DMNATSSRSHAVFQIYLRQQDKTasi------nqnVRIAKMSLIDLAGSERASTSGAk-------G-TR-FVEGTNINRS 287  human
1SDM_A  198 LMNEQSSRSHLIVSVIIESTNLQtq---------aIARGKLSFVDLAGSERVKKSGS--------AgNQ-LKEAQSINKS 259  potato
O08672  594 VMNQHSSRSHALVTLTLRAAS-Pprpq--------gitgTLHLVDLAGSERVWKAGVaspvqrdpNgARrLREAQAINRS 664  house mouse
P45962  436 EANIESSRSHVIVRVLVSATNLItk---------atTVGRLNLVDLAGSERVSQTN---------AtGQlLKEAQAINKS 497  Caenorhabditis elegans
Q9LX99  331 KFNV----THLIVSIHIYYSNTItg---------enIYSKLSLVDLAGSEGLIMENDs---------GDhVTDLLHVMNS 388  thale cress
O95235  372 HLNQNSSRSHSIFSIRILHLQgegdi-----vpkiSELS---LCDLAGSER-CKDQK--------SgER-LKEAGNINTS 433  human
Q9PUU5  293 QLNRESSRSHSVFIVKLAQAPLDadgdnvlqdknqVNVSQLCLVDLAGSERTSRTRA--------EgNR-LREAGNINQS 363  zebrafish
Q9VZF5  305 VLNAESSRSHSVFNIRLVQAPTDsqgenvvqdrqnITVSQLSLVDLAGSERSSRTKN--------T-GVrLREAGNINNS 375  fruit fly
Q9V877  346 SVNANSSRSHCVFTVDILKYNRSgi----------ttQSSYKFCDLAGSERVNNTGTs---------GLrLKEAKNINTS 406  fruit fly
P32364  227 GDKTERSRSHLVFQLHVEQRNRKddi---------lkNSSLYLVDLHGAEKFDKRTE--------StLS-QDALKKLNQS 288  Saccharomyces cerev...
5OCU_K  288 LLALGNVINALADSkr-------kNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 358  human
1SDM_A  260 LSALGDVISALSSG----------NQHIPYRNHKLTMLMSDSLGGNAKTLMFVNISPAESNLDETHNSLTYASRVRSI 327  potato
O08672  665 LLALGGVMAALRAR----------RPHVPFRDSQLTRLLQPALWaGTTAVLLLQISTRAEDLGETICSLKFAERVGQV 732  house mouse
P45962  498 LSELGNVVLALRQN----------QKHIPFRNCQLTRILEDSLNGDSKTLVIVHLSPDAKSLNESISSVNFAEKIGQV 565  Caenorhabditis elegans
Q9LX99  389 ISALGDVLSSLTSG----------KDSIPYDNSILTRVLADSLGGSSKTLMIVNICPSVQTLSETISCLNYAARARNT 456  thale cress
O95235  434 LHTLGRCIAALRQNqqn----rskQNLVPFRDSKLTRVFQGFFTgRGRSCMIVNVNPCASTYDETLHVAKFSAIASQL 507  human
Q9PUU5  364 LMTLRTCIEVLRENqmc-----gtNKMVPYRDSKVTHLFKNYFDgEGKVRMVVCVNPKADDYEETLLVMRFAEMTQEV 436  zebrafish
Q9VZF5  376 LMTLRTCLEYLRENqlaas-nglaPKKVPYRDSKITHMFKNYFDGEGQVSMIVCINPRIEDYDENMQVMKFAEMTQEV 452  fruit fly
Q9V877  407 LMVLGRCLDAASTVqkk-----knADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNVLNFASIAKNI 479  fruit fly
P32364  289 IEALKNTVRSLSMKerdsaysakgSHSSAYRESQLTEVLKDSLGGNRKTKVILTCFLS--NVPTTLSTLEFGDSIRQI 364  Saccharomyces cerevis...
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