Conserved Protein Domain Family
PLN02269

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PLN02269: PLN02269 
Pyruvate dehydrogenase E1 component subunit alpha
Statistics
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PSSM-Id: 215152
Aligned: 26 rows
Threshold Bit Score: 655.631
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
223995699   6 ATFDLTGSFETYNLDTqPNNTIEMTKDELLSHFELMYTMRRMEITCDNEYKARAIRGFCHLYDGQ------------EAV 73 
145341086   1 MVIETPVPFKGHLIVP-PSQMVETTKSEIIDMFTQAYMMRRLEIAADVLYKGKFIRGFCHLYDGQ------------EAV 67 
168017393  34 ITLDIPVPFKAHKVET-PSVTVETSAQELTNFFKTMFIMRRMEIAADSLYKSKFIRGFCHLYDGQ------------EAV 100
168047407  37 LTLEIPVPFKGHKVDP-PSSTVETSAAELVDFFRTMFVMRRMEIAADSLYKSKFIRGFCHLYDGQ------------EAV 103
255089689   1 MTIEIPIPFKAHNIEA-PSQMVETSKTEIVDMFTQAYLMRRLEIASDVLYKGKFIRGFCHLYDGQ------------EAV 67 
302758212  53 FVVDIPVPYAGHRCDP-PEQRVETSAKELVDFFKVMYVMRRMEIAADSLYKAKFIRGFCHLYDGQ------------EAV 119
302758680  53 FVVDIPVPYAGHRCDP-PEQRVETSAKELVDFFKVMYVMRRMEIAADSLYKAKFIRGFCHLYDGQ------------EAV 119
302780635  30 INVEIPVPFQLHLLQEgPARESVTSREELVKMYRDMFRIRRMEITADKLFKSQLVRGFCHLYDGQ------------EAV 97 
302781718  30 INVEIPVPFQLHLLQEgPARESVTSREELVKMYRDMFRIRRMEITADKLFKSQLVRGFCHLYDGQ------------EAV 97 
303287226   1 MMIDVPIPFVAHRIDP-PSQTVETSKAEIVDMFTQSYLMRRLEIAADVLYKGKFIRGFCHLYDGQarsishwspydrEAV 79 
223995699  74 ATGINAAFDPEDSWITSYRCHCTALARGGSVASVLGELFGHVDGQTKGKGGSMHFYNKAHNFFGGQGIVGAQ-------- 145
145341086  68 CVGMEAALNKQDAVVTSYRDHCIHLGRGGTPLEVMAELMGRVDGAAKGIGGSMHMYRREANFFGGNGIVGAQ-------- 139
168017393 101 CVGMEAALNDKDCIITAYRDHCTHLGRGGSVLEVFAELMGRKDGCSLGKGGSMHMYNKKGGFYGGNGIVGAQ-------- 172
168047407 104 CVGMEAALNDKDCIITAYRDHCTHLGRGGTVLEVFAELMGRKDGCSLGKGGSMHMYNKKGGFYGGNGIVGAQ-------- 175
255089689  68 CVGMEAALTKEDAIVTSYRDHCTHLGRGGTPLEVMAELMGRVDGASKGMGGSMHMYKRDANFFGGNGIVGAQ-------- 139
302758212 120 CVGMEAALTKEDAIITAYRDHCTHIGRGGTVLEVMAELMGRKSGCSLGKGGSMHMYNKEGNFYGGNGIVGAQ-------- 191
302758680 120 CVGMEAALTKEDAIITAYRDHCTHIGRGGTVLEVMAELMGRKSGCSLGKGGSMHMYNKEGNFYGGNGIVGAQ-------- 191
302780635  98 TIGMEAALTYEDTVITAYRDHATFLGRGGTVHECFAELMGRSTGCARGKGGSMHLYKPSNNFYGGWGIVGTT-------- 169
302781718  98 TIGMEAALTYEDTVITAYRDHATFLGRGGTVHECFAELMGRSTGCARGKGGSMHLYKPSNNFYGGWGIVGTT-------- 169
303287226  80 CVGMEAALNKDDAIVTSYRDHCTHLGRGGTPLEVMAELMGRIDGASKGMGGSMHMYKRDAHFFGGNGIVGAQassdwspy 159
223995699 146 --VPVGLGLAFANHYNatpgKPMQVAIACYGDGAANQGQIWESANMASLWKLPMIFCIENNHYGMGTSMDRHSSHSDYYK 223
145341086 140 --TAIGAGLGFAFKYN----KQPNVAVTMYGDGAANQGQLFEALNMAALWDLPVIFMCENNHYGMGTAQDRSAKSPVYYK 213
168017393 173 --TPLGAGLAFAQKYL----KVEGVTLAMYGDGAANQGQLFEAMNISALWNLPVIYVCENNHYGMGTAEWRSAKSPEYYK 246
168047407 176 --TPLGAGLAFAQKYL----KVDGVTLAMYGDGAANQGQLFEAMNISALWDLPVIYVCENNHYGMGTAEWRSAKSPEYYK 249
255089689 140 --TPIGAGLAFSYKYN----KQPNVAVAMYGDGAANQGQLFEALNIAALWDLPLIYVCENNHYGMGTTTARSAKSPEYYK 213
302758212 192 --TALGAGLAFAQKYN----KQNAVSLALYGDGAANQGQLFEAMNISALWDLPVIFVCENNHYGMGTAEWRSAKSPEYYK 265
302758680 192 --TALGAGLAFAQKYN----KQNAVSLALYGDGAANQGQLFEAMNISALWDLPVIFVCENNHYGMGTAEWRSAKSPEYYK 265
302780635 170 --GPLGAGLAFANKYE----KKNNVAMAIYGDGAGNQGQLFEAKNMAGLWDLPLIFLVENNHYGMGTAEWRASKKTTFYD 243
302781718 170 --GPLGAGLAFANKYE----KKNNVAMAIYGDGAGNQGQLFEAKNMAGLWDLPLIFLVENNHYGMGTAEWRASKKTTFYD 243
303287226 160 drTPIGAGLAFAMQYE----KKPNVAVAMYGDGAANQGQLFEALNIAALWDLPLIYVCENNHYGMGTAIAKSAKSPEYFK 235
223995699 224 MGNHIPGVRIDGMNVLAVKEGMRFVKDYVGNgNGPMYVEMMTYRYHGHSMSDPGTTYRNREEIALTRSTRDPLEFVKRTL 303
145341086 214 RGDYVPGLKVDGMDALAVKQAMKFAKEYCVAgNGPIVMEMDTYRYHGHSMSDPGSTYRTRDEITGIRQERDPVERLRKLI 293
168017393 247 RGDYIPGLKVDGMDCLAVKQAVKYAKEYALQ-NGPMVLEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIRKLL 325
168047407 250 RGDYVPGLKVDGMDCLAVKQAVKFAKEYSLK-NGPMVLEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIRKLL 328
255089689 214 RGDYVPGLRVDGMDALAVKQAIKFAKAHCVSgAGPIVLEMDTYRYHGHSMSDPGSTYRTRDEITGIRQERDPVERLRKLI 293
302758212 266 RGDYVPGLKIDGMDVLAVKQGVRFAKEHALT-KGPI--------------------------------ERDPIERVRKLL 312
302758680 266 RGDYVPGLKIDGMDVLAVKQGVRFAKEHALT-KGPIVLEMDTYRYHGHSMSDPGSTYRTREEISGVRQERDPIERVRKLL 344
302780635 244 RVSYIPGIKVDGMDAFAVKEATRFAKEHCLSgKGPIVLEADTYRYHGHSMSDPGSTYRTRNEIQGVRQERDPIERIKKLM 323
302781718 244 RVSYIPGIKVDGMDAFAVKEATRFAKEHCLSgKGPIVLEADTYRYHGHSMSDPGSTYRTRNEIQGVRQERDPIERIKKLM 323
303287226 236 RGDYVPGLKVDGMDALAVKQAIKFAKEHCVSgKGPIVLEMDTYRYHGHSMSDPGSTYRTRDEITGIRQERDPVERLRKLI 315
223995699 304 VDAGFTDAEEIKEIEKRIRKDVANQVKQAKASSKPTvEPHLFEYVYSSDGGKEQNEFP---PHIRMPDF 369
145341086 294 TEHNLLDATQIKQIEKEQRRIVDEAVEQAKASPLPP-NENLTKNMNTNLENIVVRGVD---SQTFHALV 358
168017393 326 LSNNIATVAELKTMEKEAKKEVEDALSKAKESPSPD-SDELFTHVYRKGYGAKAYGAD---RKEVVVKL 390
168047407 329 LSHEFASVADLKAIEKEAKKEVEDALAKAKESPSPD-APELFSHIYRKSYGAEAYGAD---RKESTVKL 393
255089689 294 QHHELLAPEEIKAIEKTQRKIVDDAVAAGKASPEPD-SNALFRNMNQVAEGIVIRGVDsgaRTTLATVQ 361
302758212 313 LAKEIVTVADLKNLEKQAKAEVDEAVNQAKEGGQPE-THELFTHVHVKGLKQLAYGPD---RKEVIVPL 377
302758680 345 LAKEIVTVADLKNLEKQAKAEVDEAVNQAKEGGQPE-THELFTHVHVKGLKQLAYGPD---RKEVIVPL 409
302780635 324 IKENVMREEEFKAVDKEIKQEVDDAAAKAKDDPNPG-EEELFMNIYKNDSGLKTYGCD---RNMVRVQL 388
302781718 324 IKENVMREEEFKAVDKEIKQEVDDAAAKAKDDPNPG-EEELFMNIYKNDSGLKTYGCD---RNMVRVQL 388
303287226 316 VEHELLDTAEIKAIEKAQRKIVDEAVAAGKASPEPP-VENLMKNMNQIMDNVVVRGVD---SEARTHLT 380
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