EKC19732 124 PGQNVYGILRAKRSASTEAVVLTTPM-Rp--kDSDLPSTTGGIVLMLAMAKYFRRQTYWSKDIIFLVSD---------HE 191
ABN67298 116 ANDTLYAIMHAPRGDDTEAMVLTVPW-V----TSEGEYNEGGLALAAGLARYFSKMSIWSKNIIFVFPQ---------DS 181
CAR65473 116 GTNTLYGIMHAPRGDDTESMVLAVPW-T----TSTGQYNEGGVAISVALLRYFNKMSIWSKNIILVFPE---------DG 181
CCE80716 116 GDDTLYAIMHAPRGEDTEAIVLTAPW-S----TSEGSYNVGGIATAVALLRYFKKMSIWSKNIILVLPE---------DG 181
Q9US48   122 NGSNFITTLRAPRGDATESLLLCVPW-K----DHIGQYNEAGVALAISLLKYFQGWSLWSKDIILVIFD---------DP 187 Schizosaccharomyces...
CCA69779 128 AGVNAYGTFRSPRTSGAEAIVIVASWiSredeGQKRQPNLRGIATVLSLANNLRRQSVWAKDLIFLVSD---------SY 198
EGF76976 143 KGYNIHGVLRAPRGDGTEAMVLTAPL-T----LADNAFNANGIRYLLQLAKFLKKYSFWSKDIIILVTT---------NN 208
KRG93229 147 FGINTVGIIRAPCGDGKEASVLVTPYn----pNKVGLGEAFSLGIAYSVFSLLSRVTWLAKDIVWLVADsq------yGE 216
Q95X60   135 NGENVYGFIRGPRNDGAEAQMIVVQLgR-------SEKSRRMMSRMLAFVDYAKDQVYWARDIVIVFVDggekndsieKA 207 Caenorhabditis elegans
EFO84723 119 RGENVYGFIRGHRNDGAEAQLIVVQLgR-------SESARRMISRMLAFIDYAKEQVYWARDFVIVFVDggdkkesidQA 191

EKC19732 192 QIGLQAWLDGYH----------DIKSEy------iVPSDV--MGR-------SGAIQAAINLEI---PDGnIRYFDIKIE 243
ABN67298 182 HAVLRSWVEAYH-------------------------TTL--EQT-------AGSIDAAIVLEYg-kNGDyFDYFEMYYE 226
CAR65473 182 HASLRSWVEAYH-------------------------TSL--DRT-------AGSIEAAIIMEYe-gVADyFDYYEINYE 226
CCE80716 182 HVALRSWVEAYH-------------------------TSL--DET-------AGSIEAALVIEYg-sASDhFDFYEVVYE 226
Q9US48   188 VYGPSSFLTSYF----------DQTTPy------iSYTPL--KIR-------SGSIQAGLSLELv-tTENnSDVLEVLYQ 241 Schizosaccharomyces...
CCA69779 199 LDGAHAWLSEYHgssq----------------kglVAQPLndPEP-------AGVIWTALVIDY---PGHsFSHLGLFFE 252
EGF76976 209 AYGTYSWLQAYH----------GFKPDvkq---glIFDSL--DTH-------AGSIQSAISLEFp-gTED-YTSIGIFPE 264
KRG93229 217 YSGVAAWLRAYQapsiqrldivNSETCngssifneLGQGLylDGKlyggfrhAGTMAAALVIKVaeqGNQyEDSLNIYAE 296
Q95X60   208 AFALDAFLLKYQk--------iEALNSkks--itvEADEI--QAQ-------TGALIGGVVYDLsgmAVKgQHIVNIQTN 268 Caenorhabditis elegans
EFO84723 192 AFALDAFLFKYQk--------iEALTSkqsn-gtvIADEI--QSQ-------TGALIAGVVYDLsgmSIKgQHIINIQTN 253

EKC19732 244 GMNGQLPNLDLFNLVV-KICNQE-GVDVSFHRNFD-------------PMDpqs--------------vdGYVQSVKTML 294
ABN67298 227 GLNGQLPNLDLLNTIS-NVAYHE-GIHCVIQNTPS-------------TELvr----------------nDYYSRTRTLL 275
CAR65473 227 GLNGQLPNLDLLNTAN-TVGHHE-NLQCSIQSTPA-------------NQLst----------------nTYFSRLRVLF 275
CCE80716 227 GLNGQLPNLDLMNTIN-LIGYHE-NIGYSIQGTTR-------------DELqk----------------rTYSTRLRTLL 275
Q9US48   242 ATNGQLPNLDLFNTIS-RIFMQHfNYPLRLQGYDF-------------HANsg----------------sSYTSRLKSLW 291 Schizosaccharomyces...
CCA69779 253 GTNGRLPNQDLSNSL--SVISRNmGVPLVLYDHKD-------------DQIhrgpailqpladlfdinlpDYVRRVRNIG 317
EGF76976 265 GINGLLPNADLVTTIIlSISDPYyGSPLELHHGDH-------------KTVgys-------------mtdQYLACIKRLW 318
KRG93229 297 ASNGQMPNLDLINIVN-YLAVHKqGLRIKVKKMWSllgsrwlytlgviFESlgkisrslnpqwkfgipatEYVEGAATLA 375
Q95X60   269 GLNGQQVNLDVFNGIT-KIADSKhHSRVAIFGTLH-------------RHSnp----------------yMEYSPFIVPM 318 Caenorhabditis elegans
EFO84723 254 GLNGQQVNLDVFNGIV-KIADSKhHSKVAIYGLMH-------------RHAsp----------------yKDYSPYDVPL 303

EKC19732 295 EMMWSQAAGTP---SGNHGLFHKYHIEAVTL--QGIRrk-----nsNYAFPLERTGRILEGIFRSLNNLLERFHQSFFFY 364
ABN67298 276 RGILNLTLSGLkrdVPGCAAFSGWQIQAVTI--RAKGt--------QGPHDVTQFGRVVDTSFRSVNNLLEKFHQSFFFY 345
CAR65473 276 RGILNLALAGLnrnTPGCEAFSGWSIQAFTV--KARGt--------SGPADVTQFGRIVDSTFRSVNNLLEKFHQSFFFY 345
CCE80716 276 KGILNLALVGLkkkTPGNEAFSGWQIQAVTV--RAKGv--------DGPSDVTQFGRIIDSTFRSVNNLLEKFHQSFFFY 345
Q9US48   292 MGMLTQAVSNV---TSAHALFPQYRIDMLTLrmKVKD---------PFSFDMFRFGQAIESTFRSLNNLLEHLHQSFFFY 359 Schizosaccharomyces...
CCA69779 318 RHVSYQAIGEP---SGVHGLFHRYRIDAITL--YTVPa--------TGPHGFHSLGRVIESLLRTTNNLLERLHASFFFY 384
EGF76976 319 RFIGYQASCMP---KASHALFLQYKIEAITL--RGLVip-----gfSQSVGAIQVGQILENALRSFNNLLEKLHHSYWFY 388
KRG93229 376 SSLYYQGLGVP---TGPHGAFRDYQVDAITL---EISpkvsltkmiRRNEFILRGGRLIEGVIRSINNLLEKFHQSFFLY 449
Q95X60   319 RALYTQAFISI---EGIHSVLGKYGVQGLTVg-------------lSHDYSEKQTGQFIEEVSRMLNNVLERLHQSYFMY 382 Caenorhabditis elegans
EFO84723 304 KALFTQAFVSI---EGIHSVMGKYGVQGLTVg-------------lSHDYSERQAGQFIEEVSRMLNNVLERLHQSYFMY 367

EKC19732 365 ILPGTRNYISIGMYMPPFGLIcATGLIKISLLLFLpVENEDKEKKKEKEKsekEGeEdedregkhteeeldkeveelrkt 444
ABN67298 346 LMLSTKHFVSIGTYLPAAVFI-AVSFAFSALGCLL-NSGVEASSFFNN-------------------------------- 391
CAR65473 346 LMLAPNHFVSIGTYLPSAILI-AVAFAISSFGCLL-NSGLQMSLFLGT-------------------------------- 391
CCE80716 346 LMLSPDNFVSIGTYLPAAVLL-AVAYVLSSLGCLV-INEVQAKFIAQS-------------------------------- 391
Q9US48   360 FILDHLHFISIGNYMPSILIL-AASFMLGAYRHWInH------------------------------------------- 395 Schizosaccharomyces...
CCA69779 385 LFTAPSEFAEFARYLPPVIIL-GLAASFGGLHLYVqTGWIQHEERSEKDDeddEGkLvwhm------------------- 444
EGF76976 389 FMPTASEFIPISVYIAPVAIL-ASSIIIFSIGKWWeTPFALIASKNLKIDq----------------------------- 438
KRG93229 450 LLTSPSKFVSVGVYMIPFALLvAPLPIVAA---YLhVNASDSTPQTTSALevnASpKs---------------------- 504
Q95X60   383 VLADDLHFSSIAMYIIPLTIL-VSPLVISA---YFeWTKIQEFQ------------------------------------ 422 Caenorhabditis elegans
EFO84723 368 VLSDDMHFISIALFVIPIGIL-ISPLVFLV---YFeWKKCQVFH------------------------------------ 407

EKC19732 445 imdedveEEAAAEGLIS--IMPVILISL---MMG-----VFSYTGPDFitmsapp--------------frikmedNISF 500
ABN67298 392 -----------TGSLLF--IFTVIELSS---GVLaaalpWITFGSPAEyq--------------------------dTTV 429
CAR65473 392 -----------FNKLLI--FFTSVESVC---FTIsillpYLVKLSANEek---------------------------lGV 428
CCE80716 392 -----------AYKILT--IFIFVELGC---LMLaktlpLFVLGSDDDes----------------------------vA 427
Q9US48   396 -----------EKKIDLwrPFSFWLFSIfctIAA-----YYLVSSSTKit--------------------------vFIF 433 Schizosaccharomyces...
CCA69779 445 ----rdrPVLE--------VLCIMGATH---LVGiatlaIVHQAWFWAlvqe---------------------adlSLAI 488
EGF76976 439 ----------sASSIYVhrVLGVTSFTH---FVRpmflpLLTLATSFGacswmmvniet-------ityisamrtdLFAL 498
KRG93229 505 ------wKWLN--------SARKVLVIH---LWG-----AVISLLPFFlcqvpn----------------ttptmnFVLW 546
Q95X60   423 -------------------FPVVHLAFH---VLG-----FFYYIATTYvfqtigttfvlqwmqwpfvgidgcdgqfTPSW 475 Caenorhabditis elegans
EFO84723 408 -------------------FPLTYPFIH---FIG-----YMLYLFTTWtykhvgtryvfqwtqypfigkegcdgafSPLF 460

EKC19732 501 GLMALYTASLMVPRLISRKQP-------GAgKKLifDWQLLKCVTLLYQSLFLFSVSLMNISLAFFLAVIL-MPITVIVQ 572
ABN67298 430 AQILFVLSLLTFGLAFTPLIMtkt-kkvKFsKSI--TFGLI-SLSLFYISMLITTLLIVNFSLALTVGLLS-LPLTFIQP 504
CAR65473 429 NIVLYGLIYNSVAISISPNFNipslkkyKLsKEL--TYMLI-SMSLFWIALLITTLLIVHFALALSIGFFA-LPLTFIQP 504
CCE80716 428 ALILYGFTVLTFASFVLSIKNqwipkkyRMdKSL--TFCLI-ALALFLISLLLTALLIVNFALAFLIGLAA-LPLTFIQP 503
Q9US48   434 LYLMLTFIGIIFSTFMTSE-----------------DAELVLSYDLMSKSLFISVVSTLNFSLSFVVAILL-VPLQFISF 495 Schizosaccharomyces...
CCA69779 489 GIVSVPSVLLLLAVGVYSFAIrpl---------pptTPALLKALNLCCLGVVISVIAVANFSLSVTIAVLAtVPLCLVPV 559
EGF76976 499 VETTIIGLQIFLVYYIMPFVHrlaygsgAStKTSvpAWKIVRLCCCCVLGVFLFMLAGINPSLCILVALPY-VPVFLFIR 577
KRG93229 547 GLLSAFSLLILYMILGSPIFEa------AAsRPEknKWASLKSVTISTAFIGLSLMSVINFATAEIGALHI-VPICLMAR 619
Q95X60   476 SLINSFLIFFMIPLGPYVFLKep-----------vrCVPSMRIVCLLETSLVLYGICLTNFGLAILCTAFV-VPIVFL-- 541 Caenorhabditis elegans
EFO84723 461 DLMHSFLLFSVVPFGLYAFYKvp-----------vpCVPTMRIFCLVETTLAIVALALTNVGLGIFTSAVV-VPVVFL-- 526

EKC19732 573 ----------------------PTKI---RLLLWIQKFFL-------------LLVSPGVLLFIAAVItSYGEKHAdfld 614
ABN67298 505 iisqks-----------nltksPQVVsnrKRAQVKVSLCL-------------LVSSPWFVVFL----------AGsyld 550
CAR65473 505 iitna------------nlkslGKANnskYLSKIKVTACL-------------VMSSPIFIIYL----------IGnvfi 549
CCE80716 504 lvttsnlkllsespkekrkdllSYLVndgNSKRLKIGLCL-------------LVSSPFFIIYI----------IGnlfv 560
Q9US48   496 rf--------------------------nRRLSLLFAVLTyfstfiflcslskILNGPLVPF------------------ 531 Schizosaccharomyces...
CCA69779 560 rldqp------------itenvSKLVklqPVLRPAAVAFV-------------LLISPMGLLqcarsl------------ 602
EGF76976 578 -------------------------PttsKVLRIAQIVLL-------------NLLSPPGYLllacflyg---------- 609
KRG93229 620 plk-----------------ldFQARswrTLLRASCNIALg-----------fIVFPPVAFV------------------ 653
Q95X60   542 ----------------------MTYEssdRTRSIFRSSVL-------------AILNPISVLAFVAIN-IPGMFGQlfpt 585 Caenorhabditis elegans
EFO84723 527 ----------------------MTYEsyqRERSIFRSGML-------------AILSPMVVLTVVAYS-LPAFITViipd 570

EKC19732 615 llvnswsfmktNIFLTIID---------KY------FFGSWMFSLFSFV------------ILPNWLMFW 657
ABN67298 551 p-----engisLMRGLLTS---------LH------ELQCWTWYVVILG------------WFPAWLTIA 588
CAR65473 550 he---dqgptvLMRGLLTS---------WN------ELQCWTWFIIILG------------WLPAWLIIA 589
CCE80716 561 de---skgaliLMKGLLTS---------WD------ELQCWTWFIVILG------------WFSAWSTVA 600
Q9US48   532 ----------------------------WLwakeyeLFNSWLMPSVFMIlvlpeiifsvtsFFSLWNEPS 573 Schizosaccharomyces pombe 972h-
CCA69779 603 ------galypTLTDVAISgwlrrilweAV------ILKTWFVPITCAV------------YLPLVLQGL 648
EGF76976 610 ----dtavvaqAVKDAVFD---------WH------FFGSQLVPFVCLL------------IWPLNLTAQ 648
KRG93229 654 -----------LLKGAFEDfygmnfgdyWNwveslwVWNSATYLYVGVV------------HLPCWALCI 700
Q95X60   586 isqdswlaaaqSIALTAIRed--------------vEFKVNHFFLLCCF------------GYPIWNMLF 629 Caenorhabditis elegans
EFO84723 571 kayqtvigvpvFMLQTMIQtd--------------aANGSWHLFLMTCV------------AWPVWNMIF 614