Conserved Protein Domain Family
Acatn

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pfam13000: Acatn 
Acetyl-coenzyme A transporter 1
The mouse Acatn is a 61 kDa hydrophobic protein with six to 10 transmembrane domains. It appears to promote 9-O-acetylation in gangliosides.
Statistics
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PSSM-Id: 372424
Aligned: 16 rows
Threshold Bit Score: 612.443
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_004181310          23 FFLLVLLYFLQGIPVGLTFGTIPFLLKSIAKETSFASLGFFSIATYPYSLKIFWSPIVDSLYFKKLGRRRSWIIPIQFIS 102
Q6CKM4                11 FYLLVVLYLLQGIPVGLTFGTIPFILKSSQRQTSFVTIGLFSMATYPYSFKILWSPIVDSWYSQKVGRRRSWIIPVQFVT 90  Kluyver...
LoveMIT:GQ68_00059T0  75 FALLVMLYLIQGVPIGLAFGTIPFLLKG--SNLSFSQVGVFSLASYPYSLKLLWSPIVDSLYFKNIGRRRSWIIPVQAVS 152
Q75EB1                52 FYLLVALYFLQGIPVGLAFGTVPFLLKSIAKDTSFTKLRLFGIATYPYSLKIHWSPLVDSFFSKKIGRRRSWIIPVQLAS 131 Eremoth...
ybcl:Ecym_3067        18 FYLLVVLYFLQGIPVGLAFGTVPFLLKSVAKDTSFTKLGVFSMATYPYSLKILWSPIVDSIFNPKVGRRRSWIIPIQFIS 97 
CAR30301              16 FFLLVVLYFLQGIPVGLAFGTVPFLLKSGARETTFTQLGVFALATYPYSLKIIWSPIVDSIYSKKTGRRRSWIIPVQLAS 95 
XP_003958394          19 FYLLVILYFLQGIPVGLAFGTVPFLLKSLVKETSFTSLGLFSMATYPYSLKILWSPIVDSFYNKRIGRRRSWIIPIQLIS 98 
CCK72933              21 FYLLVALYFVQGIPVGLAFGAIPFLLKSMAKQTSFTSLGVFSVATYPYSLKILWSPIVDSCYSRKIGRRRTWIIPVQLVS 100
XP_003670744          18 FYLLVALYFVQGIPVGLAFGTIPFLLKSMVKETSFTSLGVFSIATYPYSLKILWSPIIDSLYSKKIGRRRSWIIPIQLAS 97 
XP_003677802          42 FFLLIALYFVQGVPVGLAFGTIPFLLKSMAKETSFASLGVFSIATYPYSLKILWSPIVDSFYSKKIGRRRSWIIPIQLTS 121
XP_004181310         103 GLLLIIFSYAIKHDYIFPgidsqfnfnnnsdsDKtledyVSNININTLTFYFGVLIFLCATQDIAVDGWALTILSQKSIS 182
Q6CKM4                91 GITLLTLGYCISKDKILP--------------KD-----VSKVDMKALTSVFLFLVILCSTQDIAVDGWALNILSKESLS 151 Kluyver...
LoveMIT:GQ68_00059T0 153 GLMLLFLS---------Tqvda--------------lflDLEANLYRLTIVFFILILLCATQDIAVDGWALTILSPSALS 209
Q75EB1               132 GVMLWCVGHAVAQGWVFEgvdasy---gapslGD-----GAKINITSLTVCFLVLVFFCATQDIAVDGWALTILSRQSLS 203 Eremoth...
ybcl:Ecym_3067        98 GLMLWIVGYLISKGLLFEgvdaay---nvsspDT-----LSDINVTSLTVCFFVLVFLCATQDIAVDGWALTILSKQSLS 169
CAR30301              96 GIILWAIGFCVSNNLVFAgiddsystgnapvkQG-----VRPTDITTLTICFLLLVFLCATQDIAVDGWALEILSKQSLS 170
XP_003958394          99 GIILWLIGWGISNNLIFEgvdnpf---hgrdtDV-------KTNITQLVFWFGLLVILCATQDIAVDGWALTILSKRSLS 168
CCK72933             101 GLILILLGWMISHNYIFEgvdnaf----hglpiG-----LTNVNIMSLVWYFGLLVFLCATQDIAVDGWALTILSKQALS 171
XP_003670744          98 GLMLYILGHCISKGYIFSgvdaaf--hpeqtvES-----MRTVKISTLTWYFGSLVFLCATQDIAVDGWALTILSKRSLS 170
XP_003677802         122 GIMLYTLGLCISKGYIFQgvdaaf--hsgessEK-----IHNVNILTLAWYFGSLVFLCATQDIAVDGWALTILSTQSLS 194
XP_004181310         183 YASTAQTVGLNTGYFLSFTVFIAMNSKDFANKYLRSTPlehgLISLNGYMKFAGILYILTTLYVMFFTTENvkslhnen- 261
Q6CKM4               152 YASTAQTIGLNIGYFMSFTIFLSLSSDEFMQKYFHRDR----LFQLSSYLTFTGLLYLAVTFYVSLFTSEK--------- 218 Kluyver...
LoveMIT:GQ68_00059T0 210 YASTAQTIGLNTGYFMSFTIFLAFNSPDFANKYFRKVPsdvgPITLSGYLYFFGWIFLSVTVFLWFKVPEQpahl----- 284
Q75EB1               204 YASTAQTVGLNTGYFLSFSIFLAFNSGDFVNRYFRALPldhgIISFSSYLKLSGWMYLILTAYVVFFTQEYpyahs---- 279 Eremoth...
ybcl:Ecym_3067       170 YASTAQTVGLNTGYFLSFSIFLSFNSGHFLNKYIRSTAqdygLVSFSGYLKLSGWIYMLVTLYVVFYTTEHpvtsg---- 245
CAR30301             171 YASTAQTVGLNTGYFLSFTIFLTFNSSDFMNRYIRSEPleygLISFGGYLKFAGTVYLAVTFYIMFFTNERpsncs---- 246
XP_003958394         169 YASTAQTVGLNIGYFLSFTIFLSLNSSEFVNKYFRNVNkpygLVSLGGYMKFAGTIYILITVYIIFCTKEHplateqtls 248
CCK72933             172 YASTAQTVGLNIGYFLSFTVFLSLNSNDFVNKYFRAEPkpygWVSLGGYMKFSGIVYILLTMYVVLFTKERpprvrn--- 248
XP_003670744         171 YASTAQTVGLNMGYFLSFTVFLSLNSGEFVNKYFRKIPqkfgWISLGGYMKFAGFVYVIVTIYVGFCTTENpfisnkk-- 248
XP_003677802         195 YASTAQTVGLNMGYFLSFTVFLSLNSNEFINKYFRKIPqnygWVSLGGYMKFSGLVYILVTIYVVFATRENpfnsnr--- 271
XP_004181310         262 kshlptiLNERppefITiEKEPEfystdsltsnsNSNSNSNfkkALSNNDNLSNIKLVYKNFWKILNLKNIQILSIIHLF 341
Q6CKM4               219 -------VHVEthshIK-KDDDE-----------KMIEYQP---DEEEDNESHDLINIYRLFIKVMKLPSVQTLAIVHLI 276 Kluyver...
LoveMIT:GQ68_00059T0 285 ----rhvSKKH----DE-EEAIEmydlnaapgtsMTSPFRD----LEPSSTFESLVSVYKKMIRVLQLPNVKLFVVLHLI 351
Q75EB1               280 --glpvvSTKP----KD-DDEKGhivts-ttknsAHIEYNE-----DSSISKTSLGAVYRSFVKVLRLPAVRSLIILHFV 346 Eremoth...
ybcl:Ecym_3067       246 --glpmaSLKK----DD-DDVKEvdmvnssgrpfTPVEYED-----NSPIEKASVISVYKSFIKVLKLPAVQSLIILHFI 313
CAR30301             247 --vlpstAKKS-----D-EK--------------QVIDYNV-----ETGASSISLKNVYLLFFKVLKLPSVRSLMLIHLV 299
XP_003958394         249 nghlpsnIDQI--------KEFElk-------qiEIIEYNDf--NELNTENTQDITYIYRCFIKALKLKSVQSLAIIHLI 311
CCK72933             249 -lalpqtTNQG-----I-EK--------------AELEYQDg-dVATDEKDTQDIGYIYRCFLKVLGLPPIRMLVFIHLI 306
XP_003670744         249 tgilpyhIDTSedihIE-EKKDDd----------LYIETNGdeeDGF-SDRTRSLGFIYKCFFKVLKLKSVRTLTFIHLI 316
XP_003677802         272 -nilpsfDKEH-------EKKQEm----------IIVEHGGggdDDYDNDKTRNIMYIYRCFIKVLQLKTVRTLAFIHLI 333
XP_004181310         342 SKFAFQCNESSTNLKLLELGFKREDLAVTVLIDFPFEIIFGYYVAKWSSDVnhdlrikdndlssnsnsttntnsryyrSS 421
Q6CKM4               277 SKFAFQCNDAATNLKLLEKGLKREDLAITVLINFPFELLFGFYVARLSRAG---------------------------YS 329 Kluyver...
LoveMIT:GQ68_00059T0 352 SKIGFQVNDGATNLKLLEKGFTKEDLAIAVLIDFPFELVFGYYTARWSAGEe---------------------------- 403
Q75EB1               347 SKFPFQCSEGATNLKLLEKGLKKEDLAITVLVDFPFEIIFGYYVAKWSSEShhsh-----------------------qr 403 Eremoth...
ybcl:Ecym_3067       314 SKFAFQCNEGATSLKLLEKGFKREDLAITVLIDFPFEIIFGYYVAKWSSESnkde-----------------------pk 370
CAR30301             300 SKFAFQCNEGATNLKLLERGFKREDLAVTVLVDFPFEIIFGYYVAKWSSSAtfg---------------------prkFE 358
XP_003958394         312 SKLAFQCNEGATNLKLLEKGFKREDLAVTVLIDVPFEIIFGYYVAKWSSDGgiekkedeqh-------gsilrakqleKN 384
CCK72933             307 AKVAFQCNEGATNLKLLERGFKREDLAVTVLIDVPFEIIFGYYVAKWSSDAdqsrdgah-----------gsilrakrEG 375
XP_003670744         317 SKIAFQCNEGATNLKLLEQGFKREDLAVTVLIDVPFEIIFGYYVAKWSSDSenerhhhsd---------teahkntksPV 387
XP_003677802         334 SKIAFQCNEGATNLKLLEKGFKREDLAVTVLIDVPFEIIFGYYVAKWSSDSemgrmetsnr-------ypngmrrsssAT 406
XP_004181310         422 LMERINLFLVGEYGVLTPWLYGFLGRLVAAIMGNFVLYFFPED-GIITKKYFLLVILQHLLGSFMSTVQFVSISAFHSRI 500
Q6CKM4               330 FNNKIIRAVAGDARTLTPWIIGFIGRLSAAILGNVVVYLFPEDeSEISMSFFLLVLCQHLLGSFMSTFQFVSMSAFHTQV 409 Kluyver...
LoveMIT:GQ68_00059T0 404 --------------pLKPWRYGYIGRLIAAMLGQLLVWSFPS--GGVTTPYFFAVISQHLLGSFMSTVQFVSICAFHTQI 467
Q75EB1               404 kLPAFLTLLIGQPGILTPWIIGYIGRLIASMLGSFILSQFPEN-GNITKGYFLLVVTQNLLGSFMSTVQFVGVSAFHTRI 482 Eremoth...
ybcl:Ecym_3067       371 tTHPIIRSIVGNAGVLTPWLVGYLGRVIAAILGSYVIAQFPVD-GRITKRYFLLVIIQNLLGSFMATVQFVGMSAFHTLV 449
CAR30301             359 RSNFFARMLVGEAGILTPWLWGFLGRLLSAFLAGILVAKFPSD-GIVTRSYFLMVIFQHLLGSFMTTVQFVAICAFHTRI 437
XP_003958394         385 IMKRITSVLVGDAGVLTPWLYGFLGKLVAAMLGSYVLKMYPED-NKITTSYFLLVIVQHLLGSFMSTVQFVGISAFHTRI 463
CCK72933             376 ALQRINRFFVGDAGVLTPWLWGILGRLTAAAMGSFVVARFPSD-GQITTGYFLLVVFQHLLGSFMNTVQFVGISAFHTRI 454
XP_003670744         388 RFRKWIKWFVGDAGVLTPWLWGYLGRLLSAILGSYVIHQFPKN-GELTKGYFFLIIIQHLLGSFMATVQFVGISAFHTRI 466
XP_003677802         407 RSNKLIRALVGDAGVLTPWLWGFLGRLLSATLGSYVVHQFPQD-GQMTRGYFLLVIIQHLLGSFMATVQFVGISSFHTRI 485
XP_004181310         501 ADPKFGGTYMTLLNTLSNLGGTWPRIIIMWMISYFSIYDMVLEKDNVATL---------------------GT-TIIRDG 558
Q6CKM4               410 ADPVIGGTYMTLLNTLSNLGGTWPRLLIMSMIDFFSKYDCTGVPLIQGQSltkeq-----------cvsigGQlNTIRDG 478 Kluyver...
LoveMIT:GQ68_00059T0 468 ADPTIGGTYMTTLNTLANLGGQWPKIIVFTLIDKFTKAKCILPATVKEPTlsqlgntcanahtkelcqsvgGKcQIITDG 547
Q75EB1               483 ADPAIGGTYMTLLNTLSNLGGTWSRIVVMAMIDFFTSKVCQNsaigmfpp-------------eakclesgGTlVILRDG 549 Eremoth...
ybcl:Ecym_3067       450 ADPLIGGTYMTLLNTLSNLGGTWSRFLVMTMIDHFTTYDCKGIEDNIVTItkqqc------------lkkgGQpIIIRDG 517
CAR30301             438 ADSAIGGTYMTLLNTFSNLGGTWPRLLVMTMIDRLTKHECVGTgaqpldatd-----------eglckaagGTwMIVRDG 506
XP_003958394         464 ADPILGGTYMTLLNTLSNLGGTWPKIFIMSMISKLTTYECHITGKDKDTIeivhvgme------ictktlgGEvHILKDG 537
CCK72933             455 ADPVLGGTYMTLLNTLSNFGGTWPRIIVMSMINHFTLFKCVAENG----Vtfvrgtge------lcttelmGTpTLVRDG 524
XP_003670744         467 ADPVLGGTYMTLLNTLSNFGGTWPRFFVMSMINYFTIYECELPNSEERNLvfkggnme------vctnglhGEvKIIRDG 540
XP_003677802         486 ADPILGGTYMTLLNTLSNFGGTWPRIFVMWLINYLTIYECKTPDT-EKNIifsggnmd------vctkglnGEvIILRDG 558
XP_004181310         559 YYITNIICIVIGIILYFGYFKYIMGKLQKLRINMWR 594
Q6CKM4               479 YYITNLFCIVSGLLIFTTYLKPTAIKLCKVPLDQWK 514 Kluyveromyces lactis
LoveMIT:GQ68_00059T0 548 YFATNVLCIAIGFLLYFGWIKRTANHLQSLPSTAWR 583
Q75EB1               550 YYMTNLLCIGFGLLI-FPHIRRKAQHLQSLPISSWR 584 Eremothecium gossypii
ybcl:Ecym_3067       518 YYVTNFICIFVGLFLFFTYTRRKVQYLQALPISAWR 553
CAR30301             507 YFVSNFCCITVGIVLYFTFIRKRAQRLQLLPESAWH 542
XP_003958394         538 YYITNIICIILGTILYFGFLKKKAQQLQKLPISDWR 573
CCK72933             525 YYVVNTVCVLLGIVLYFGFLKREAQVLQKLPVSAWR 560
XP_003670744         541 YYVTNALCVVLGVILYFCYLKRKAQQLQTLPISAWR 576
XP_003677802         559 YYLTNAICVSIGLCLYVFYLKKKAHQLQSLPVTAWR 594
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