1QO8,1QJD


Conserved Protein Domain Family
flavo_cyto_c

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TIGR01813: flavo_cyto_c 
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flavocytochrome c
This model describes a family of redox proteins related to the succinate dehydrogenases and fumarate reductases of E. coli, mitochondria, and other well-characterized systems. A member of this family from Shewanella frigidimarina NCIMB400 is characterized as a water-soluble periplasmic protein with four heme groups, a non-covalently bound FAD, and essentially unidirectional fumarate reductase activity. At least seven distinct members of this family are found in Shewanella oneidensis, a species able to use a wide variety of pathways for respiraton. [Energy metabolism, Electron transport]
Statistics
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PSSM-Id: 273816
Aligned: 11 rows
Threshold Bit Score: 595.86
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1QO8_A       123 QVLVVGAGSAGFNASLAAKKAG-ANVILVDKAPFSGGNSMISAGGMNAVGTKQQTAHGVED-KVEWFIEDAMKGGRQQND 200 Shewanella frig...
Q02469       153 DVVVVGSGGAGFSAAISATDSG-AKVILIEKEPVIGGNAKLAAGGMNAAWTDQQKAKKITD-SPELMFEDTMKGGQNIND 230 Shewanella frig...
Q9Z4P0       145 QVLVVGAGSAGFNASLAAKKAG-ANVILVDKAPFSGGNSMISAGGMNAVGTKQQTAHGVED-KVEWFIEDAMKGGRQQND 222 Shewanella frig...
P21375        36 PVVVIGSGLAGLTTSNRLISKYrIPVVLLDKAASIGGNSIKASSGINGAHTDTQQNLKVMD-TPELFLKDTLHSAKGRGV 114 Saccharomyces c...
WP_011071625 149 QVIVIGAGAAGHAAAISARQHGvADVVILEKQPYIGGNSMLAAGGMSAAETVTQALKHYPD-SKALWYEDTMKGGHNINN 227 Shewanella onei...
WP_010820520  61 DVVIVGSGGAGMTAALQAKEAG-MNPVILEKMPVAGGNTIKSSSGMNASQTKFQEKEGIKD-SNDKFFEETLKGGKGTND 138 Enterococcus fa...
1QJD_A       128 dvvvvgsggagFSAAISATDSGaK-VILIEKEPVIGGNAKLAAGGMNAAWTDQQKAKKITD-SPELMFEDTMKGGQNIND 205 Shewanella frig...
WP_011071618  43 DIIVVGSGFAGLSSALNAKRQGlGSILVLEKMQVIGGNSAINGGWLAIPKNPIQLAQGIQDdSPEELVKDQIISGRGMQN 122 Shewanella onei...
WP_011073179  38 DIIIIGSGFAGLSAAYSAHKAGiKNIIVLEKMEAFGGNSAICGGLMCMPLTPMQKKLGIED-SAELMIKDMLKAGRGFNH 116 Shewanella onei...
WP_011074216 134 DVVIIGSGGAGFSAGLEAIAAGr-SAVIIEKMPIIGGNSLISGAEMNVAGSWVQKNMGITD-SKELFISDTLKGGDFKGD 211 Shewanella onei...
WP_028767438  39 EVVIVGSGFAGLAAAVEAGKLGaKDIVVFEKLGVYGGNSTLNAGQACFADTDLQRKLGIKD-SAELMVKDQLASGRGYAS 117 Shewanella fidelis
1QO8_A       201 IKLVTILAEQSADGVQWLe---SLGANLdDLKRSGGARVDRTHRPHGgkSSGPEIIDTLRKAAKEQG------IDTRLNS 271 Shewanella frig...
Q02469       231 PALVKVLSSHSKDSVDWMt---AMGADLtDVGMMGGASVNRAHRPTGgaGVGAHVVQVLYDNAVKRN------IDLRMNT 301 Shewanella frig...
Q9Z4P0       223 IKLVTILAEQSADGVQWLe---SLGANLdDLKRSGGARVDRTHRPHGgkSSGPEIIDTLRKAAKEQG------IDTRLNS 293 Shewanella frig...
P21375       115 PSLMDKLTKESKSAIRWLq--tEFDLKLdLLAQLGGHSVPRTHRSSGklPPGFEIVQALSKKLKDISskdsnlVQIMLNS 192 Saccharomyces c...
WP_011071625 228 PDLVKILTENGSAGVDWLq---AMGADLtSASSAGGHNAERLHRPTGgaKSGPEIVNTLKETAQKLG------VETRTNS 298 Shewanella onei...
WP_010820520 139 QELLRYFVDHSAEAIDWLd---TKGITLsNLTITGGMSEKRTHRPADgsAIGGYLVDGLVRNVREEK------IPLFVDA 209 Enterococcus fa...
1QJD_A       206 PALVKVLSSHSKDSVDWMt---AMGADLtDVGMMGGASVNRAHRPTGgaGVGAHVVQVLYDNAVKRN------IDLRMNT 276 Shewanella frig...
WP_011071618 123 TDMLRQMANRALDAYQLCid-aGVKFREgFNQQVGGHNKARAIRTQHg--VGGDITTKLYEVGKKEG------VEYRLQH 193 Shewanella onei...
WP_011073179 117 PELCRTLATEAHKAYDMLme-cGVKFQd-KVIRLGGHSAPRAHLPEs--ASGGGIVVPMHNYLRKAG------IIFQNRT 186 Shewanella onei...
WP_011074216 212 PEMVKTMVDNAVGAAEWLrdyvKVEFYPdQLFQFGGHSVKRALIPKG--HTGAEVISKFSIKADEVG------LPIHTNT 283 Shewanella onei...
WP_028767438 118 EELLRHSAELGPYIYQLTkd-cGCVYRd-HIINTGGTSATRSHQVVE--RSGAGFIRPMLKTARSYG------VKTKTRH 187 Shewanella fidelis
1QO8_A       272 RVVKLVVNDDHSVVGAVVH--------GK--------H--------TGYYMIGAKSVVLATGGYG-MnKEMIAYYRPTMK 326 Shewanella frig...
Q02469       302 RGIEVLKDDKGTVKGILVK--------GM--------Y--------KGYYWVKADAVILATGGFA-KnNERVAKLDPSLK 356 Shewanella frig...
Q9Z4P0       294 RVVKLVVNDDHSVVGAVVH--------GK--------H--------TGYYMIGAKSVVLATGGYG-MnKEMIAYYRPTMK 348 Shewanella frig...
P21375       193 EVVDIELDNQGHVTGVVYM--------DE--------N--------GNRKIMKSHHVVFCSGGFGyS-KEMLKEYSPNLI 247 Saccharomyces c...
WP_011071625 299 KVIQLVQNKQGVITGVLVQ--------GK--------H--------SKLHILGAKAVIIASGGFA-RnNELVAKYRPDLK 353 Shewanella onei...
WP_010820520 210 DVTDLVE-ENGQIDGVKVK--------MK--------D--------DKEKTVKAKAVVVTTGGFG-AnEKLITQYKPELK 263 Enterococcus fa...
1QJD_A       277 RGIEVLKDDKGTVKGILVK--------GM--------Y--------KGYYWVKADAVILATGGFA-KnNERVAKLDPSLK 331 Shewanella frig...
WP_011071618 194 YVEDFIMDGQ-QIVGLKVR--------QNyrfpdlktG--------KTIYIKANKAVILAHGGFS-RnLVLRELVDPALD 255 Shewanella onei...
WP_011073179 187 NVEEIIRGDSG-VTGIVVS--------EK--------YdfksgsnrGQFAYKAKKGVIVASGGWG-QdHQFIKTTMPAYQ 248 Shewanella onei...
WP_011074216 284 KAEKLIQDQTGRIVGVEAA--------HN--------G--------KTITYHAKRGVVIATGGFS-SnMEMRKKYNPELD 338 Shewanella onei...
WP_028767438 188 KFEGLITAADGSVLGIKVRkgyhteheDS--------G--------KLINVKAERGVLIATGGFA-AnVAFRQALDPTLG 250 Shewanella fidelis
1QO8_A       327 D-MTSSNNITATGDGVLMAKEIGASMTDIDWVQAHPTVGKDS-------RILISETVRGVG---AVMVN-KDGNRFISEL 394 Shewanella frig...
Q02469       357 G-FISTNQPGAVGDGLDVAENAGGALKDMQYIQAHPTLSVKG-------GVMVTEAVRGNG---AILVN-REGKRFVNEI 424 Shewanella frig...
Q9Z4P0       349 D-MTSSNNITATGDGVLMAKEIGASMTDIDWVQAHPTVGKDS-------RILISETVRGVG---AVMVN-KDGNRFISEL 416 Shewanella frig...
P21375       248 H-LPTTNGKQTTGDGQKILSKLGAELIDMDQVQVHPTGFIDPndrennwKFLAAEALRGLG---GILLHpTTGRRFTNEL 323 Saccharomyces c...
WP_011071625 354 G-VDATNNPGNVGDALTFAPKVGADIVDVKEIQAFPTAAAg--------KMVISGTARGAG---AIMLN-NDGERFCDEM 420 Shewanella onei...
WP_010820520 264 N-YVTTNQEGTTGDGIQMIQKVGGALVDMKEIQIHPTVQQSD-------AFLIGEAVRGEG---AILAS-QKGERFVNEL 331 Enterococcus fa...
1QJD_A       332 G-FISTNQPGAVGDGLDVAENAGGALKDMQYIQAHPTLSVKg-------GVMVTEAVRGNG---AILVN-REGKRFVNEI 399 Shewanella frig...
WP_011071618 256 KtLDCTNALGATGEVTLTAMAHGAFPVHMSFIQTGHWGSPDEg------GFGWSNALLSIGfhkGISVNvLDGKRFMNER 329 Shewanella onei...
WP_011073179 249 K-LESTAQPGATATMIKSLLSIRALPVMLDMYQLGPWATPDEk------GAGPASFFADYAfaeGIAIDpKTGARFMNEL 321 Shewanella onei...
WP_011074216 339 ErYGSTGHAGGTGDGIVMAEKIHAAAKNMGYIQSYPICSPTSg------AIALIADSRFFG---AVLIN-QKGERFVEEL 408 Shewanella onei...
WP_028767438 251 HeVGHTNARGATGDGLIAMLAEGAMPIHLSFIQSGPWASPDEg------GFGYGAGFSLYNfphSIAIDrNTGMRFMNET 324 Shewanella fidelis
1QO8_A       395 TTRDKASDAILKQPGQf-------AWIIFDNQLYKKAKMVRGYD-------HLEMLYKGDTVEQLAKS--TGMKVADLAK 458 Shewanella frig...
Q02469       425 TTRDKASAAILAQTGKs-------AYLIFDDSVRKSLSKIDKYI-------GLGVAPTADSLVKLGKM--EGIDGKALTE 488 Shewanella frig...
Q9Z4P0       417 TTRDKASDAILKQPGQf-------AWIIFDNQLYKKAKMVRGYD-------HLEMLYKGDTVEQLAKS--TGMKVADLAK 480 Shewanella frig...
P21375       324 STRDTVTMEIQSKCPKnd----nrALLVMSDKVYENYTNNINFY-------MSKNLIKKVSINDLIRQydLQTTASELVT 392 Saccharomyces c...
WP_011071625 421 GPRDKVSECIWAQKGKd-------AWLVFDETVLDRLGQLRGML-------DLGIIFKGNSADEMAKA--TKMNAQKFDQ 484 Shewanella onei...
WP_010820520 332 DTRDKVSAAINALPEKs-------AYLVFDQGVRDRAKAIDFYD-------QKGFVEKGETIEELAEK--IGMPADTLKA 395 Enterococcus fa...
1QJD_A       400 TTRDKASAAILAQTGKs-------AYLIFDDSVRKSLSKIDKYI-------GLGVAPTADSLVKLGKM--EGIDGKALTE 463 Shewanella frig...
WP_011071618 330 ADRKTCSDAIMKNRNPdgs--payPVVFFNHDDHVGAEEVTRAV-------RDQIAWKVDSLEQLAKQ--FNIPLAQLKQ 398 Shewanella onei...
WP_011073179 322 ADRRTRADAQLAVLASgtkekpnmPFVFCGEATANHAEGFKAAY-------RDGAIKKSETLEELAKR--YDVDINALQN 392 Shewanella onei...
WP_011074216 409 ERRDVISHAILAQPGRy-------TYVLWNQDIENVAHTVEMHQgelkeftKDGLMYKVDTLEEAAKV--FNIPEDKLLS 479 Shewanella onei...
WP_028767438 325 ADRKHRADLEIQRRDKdgn--phpALLIAPKHEAQKDPSMENVL-------KYNVAWEFDSVEAIAKH--FDLPLKALKQ 393 Shewanella fidelis
1QO8_A       459 TVSDYNGYVAS-GKDTAFGR-AdMPLnMT-QSPYYAVKVAPGIHHTMGGVAINTTASVLDL-QS-KPID-GLFAAGEVTG 532 Shewanella frig...
Q02469       489 TVARYNSLVSS-GKDTDFERpN-LPRaLN-EGNYYAIEVTPGVHHTMGGVMIDTKAEVMNA-KK-QVIP-GLYGAGEVTG 562 Shewanella frig...
Q9Z4P0       481 TVSDYNGYVAS-GKDTAFGRaD-MPLnMT-QSPYYAVKVAPGIHHTMGGVAINTTASVLDL-QS-KPID-GLFAAGEVTG 554 Shewanella frig...
P21375       393 ELKSYSDVNTKdTFDRPLIInAfDKD-IStESTVYVGEVTPVVHFTMGGVKINEKSQVIKK-NSeSVLSnGIFAAGEVSG 470 Saccharomyces c...
WP_011071625 485 AIKRYNDFKVK-GKDADFARkN-MADdL--QYPIYAVKIKPAVHHTMGGLKINTKTEVIDQ-NG-LPIK-GLFAAGEVTG 557 Shewanella onei...
WP_010820520 396 TIDTWNQDVNA-KDDKQFGRtTgMEAdLS-TAPYYAIKIAPGIHHTMGGVKINTKTEVLRE-DG-TPIK-GLYAAGELTG 470 Enterococcus fa...
1QJD_A       464 TVARYNSLVSS-GKDTDFERpN-LPRaLN-EGNYYAIEVTPGVHHTMGGVMIDTKAEVMNA-KK-QVIP-GLYGAGEVTG 537 Shewanella frig...
WP_011071618 399 TVAEYNKQVPQ-RIDPLFGRmMdTAVeL--KAPFIVSRIWPKVHYCMGGLKTDLGARVLHS-QTlAPMK-NLYAVGEATG 473 Shewanella onei...
WP_011073179 393 SINEWNEIVQG-KAKDPFNKpLdEKTiL--KPPYYSIRLSPKLHYCMGGVAITPNAEVIDS-NTcEPIS-GLFAAGEVTG 467 Shewanella onei...
WP_011074216 480 TIKDVNHYAAT-GKDEAFNHrSgL-VdLS-KGPYWILKATPSVHHTMGGLVVDTRTRVLDE-QG-KVIP-GLFAAGEVTG 553 Shewanella onei...
WP_028767438 394 QIEDWNGYVKA-GHDPQFGKrMdMSTgIYmTAPFIVQRLWPKVHYCQGGIQINTKAEVIAAkNG-KPIP-NLYAAGEVSG 470 Shewanella fidelis
1QO8_A       533 GVHGYNRLGGNAIADTVVFGRIAGD 557 Shewanella frigidimarina
Q02469       563 GVHGANRLGGNAISDIITFGRLAGE 587 Shewanella frigidimarina
Q9Z4P0       555 GVHGYNRLGGNAIADTVVFGRIAGD 579 Shewanella frigidimarina NCIMB 400
P21375       471 GVHGANRLGGSSLLECVVFGKTAAD 495 Saccharomyces cerevisiae S288c
WP_011071625 558 GVHGANRLAGNAIADTIVFGRIAGE 582 Shewanella oneidensis
WP_010820520 471 GLHGQNRIGGNAIADIIIYGRQAGT 495 Enterococcus faecalis
1QJD_A       538 GVHGANRLGGNAISDIITFGRLAGE 562 Shewanella frigidimarina
WP_011071618 474 GTHGGTRLSSTACLECLTMGIIVAE 498 Shewanella oneidensis
WP_011073179 468 GTHGMDRLGGCSSIDGLVFGQIAGn 492 Shewanella oneidensis
WP_011074216 554 LTHGTNRLGGNAYTDIIVYGRIAGQ 578 Shewanella oneidensis
WP_028767438 471 GVHGVSRLGGCSTPDCMAFGVTAAR 495 Shewanella fidelis
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