5MRC


Conserved Protein Domain Family
mS26_PET12

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cd23703: mS26_PET12 
Saccharomyces cerevisiae mitochondrial small ribosomal subunit protein mS26 and similar proteins
mS26, also known as mitochondrial 37S ribosomal protein PET12, is a component of the mitochondrial small ribosomal subunit (mt-SSU) of Saccharomyces cerevisiae mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. The family also includes a group of uncharacterized proteins from pezizomycotina, which show high sequence similarity with mS26.
Links
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Statistics
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PSSM-Id: 467916
Aligned: 160 rows
Threshold Bit Score: 72.9717
Created: 27-Apr-2023
Updated: 27-Apr-2023
Structure
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Program:
Drawing:
Aligned Rows:
 
RNA bindingoligomer
Conserved site includes 28 residues -Click on image for an interactive view with Cn3D
Feature 1:RNA binding site [nucleic acid binding site]
Evidence:
  • Structure:5MRC; Saccharomyces cerevisiae mitochondrial small ribosomal subunit protein mS26 interacts with rRNA, contacts at 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1          ####    # #                                                            #  ##  
5MRC_VV        8 GFKSGVFPTTRSIlkspttkqtdiinkvkspkpkgvl--------gigyakgvkhpkgshrlspkvnfiDVDNLIAKTva 79  baker's yeast
KAA8910721     9 GYKSGILPKPRDIlpklktswekeaeakakvgf----------------adpemvpkgvpmkpvprkekFAKERMAHSar 72  Trichomonascus ...
XP_024666444   8 GFKSGVLPKPRQIvprvkpafelaeeakirtgf----------------adpkmvpkgssavssgrkelSASEKIALSak 71  Wickerhamiella ...
CDO51400       9 GFKSGVLPKPRQIvepfktpaeiehaekenigf----------------rdpelipkgvpakvplkervPASFKIENSak 72  Geotrichum cand...
XP_018738116   9 GFKSGFLPHPRQIlpklktsweieeeakrtvaf----------------edpamapkgsspnppprrqvTASEKLSKSak 72  Sugiyamaella li...
ODQ67993       9 GFKSGLLPKSRLRniakefaraetdktatqgya-----------------dplfvprgsaaepiqkttkTADEIINDSak 71  Nadsonia fulves...
VVT51857       9 GFKSGILPKPRQIvepyktrkeiealekanvgf----------------rdpelipkgvkaaviplkprVTIDSIIEKsa 72  Saprochaete ingens
VBB78958       3 SRVSGVLPKPRSIvvpyasrrgfpvgqgyad--------------------ekmvprgshrfpkkktvpTEEQLIATRnp 62  Yarrowia lipoly...
OBA26354      10 GGFSGRFPRTRKIlkhltdkqkpfyteeqarveakiqetsnfpkgfdpslglpknvksfediskdpvfiNVDDYIQKTvp 89  Hanseniaspora v...
KKA03816      10 NGISGRLPKTVKIlkpitskiypyikkeqntlnqqivs------phphgfdksiglpknypsieeltkpIQAVDLNEYid 83  Hanseniaspora u...
Feature 1                        #####  #   #  ##                                                
5MRC_VV       80 epq--------sikssNGSAQKVRLQKAELRRKFLIEAFRKEEARLLHKHEYLQKRTKELEKAKELELEKLNkek--ssD 149 baker's yeast
KAA8910721    73 ekk--------kdsdsGSDTAEWRRMSSAMRRKYFIDAHTTEERMNKKAIELREKKFQEAREARLRTDTHEQse---atR 141 Trichomonascus ...
XP_024666444  72 apk--------kvkeaKTAHQEWRQKSADIRRRYLTDALETEEVLETKKAARRQKAHDDAASLRERMLQTGEse---aiK 140 Wickerhamiella ...
CDO51400      73 k------------akeDKHRAEWKTLNADIRRKYFTQSLLIQEAEEKAIMERRQRQLEEDRQARIQRLERTKvse--atR 138 Geotrichum cand...
XP_018738116  73 ppt--------kpkslNTELQQWKAEQSLIRRKYFVDAIEAQQTMDKKELQIRERQFREAAERRQQISTEHTese--aeR 142 Sugiyamaella li...
ODQ67993      72 vsq--------kqlshISPEQKLKSEKATIRRTYLSDSLRLQELNDKEEWKKLDEMAKKEKVWRAGLLKTEDse---atK 140 Nadsonia fulves...
VVT51857      73 kep--------tpggtASKRAPWRQELSAMRRSFLVQSLQNQDRAELRAMKLREKREARQEAEDLKKADPELtkqsestL 144 Saprochaete ingens
VBB78958      63 prts------akhatpRSEIHKWHLKMADLRKQYLADSLVSAERADKAKYHYHKRYLAAAEKVKEDARNAGLte---aeL 133 Yarrowia lipoly...
OBA26354      90 epk--------hkkqaKTFADELRLKSLELKRQYLKESVLKEEQSLINKHLRLKKIEESIQLKDTEQKKKLLetisvdnT 161 Hanseniaspora v...
KKA03816      84 kklsemipdevpaksdNVFLNQLRLKENELKKTYFKEVLKKEEDKIVQDYEYIQKLEKEEKKHDLISVSKFKntikvkkD 163 Hanseniaspora u...
Feature 1                                             ## ##           #  ##  ##     #            
5MRC_VV      150 LTIMTLDKMMsq------------------------pLLRNRSPEESELLKLKRNYNRSLLNFQAHKKKLNELLNLYHVA 205 baker's yeast
KAA8910721   142 LTLPTIEALLdg------------------------pFVQHRTPQEAEELRLKRAANRKLHELKHQEQKAESVLELYQQA 197 Trichomonascus ...
XP_024666444 141 LTMPTIENSLls-----------------------gsMVRPRTEEEKSVLALKRGANRKAVLAEQMKLRSAQLLELYQST 197 Wickerhamiella ...
CDO51400     139 LTLPTIQSFLtn-----------------------qpLVTRRTPEEIALLKSKREANRKAVKLKHLTQKSNDLLELYQSS 195 Geotrichum cand...
XP_018738116 143 LTLPSIDSVFne------------------------pFVIPRTPEETEELRLKRTANRKTLELRNSERKASILLELYQST 198 Sugiyamaella li...
ODQ67993     141 LTLPTINSFLnk------------------------pLVEPYTEEQRAILKAKRESNRIALETKFAEQRARQYLDLYQRA 196 Nadsonia fulves...
VVT51857     145 LTLPTIESFLnnthpstss---------itsindvsqFVVPRTRAEQKLLNTQRKANLVRKRLAETESRARSFLELYQST 215 Saprochaete ingens
VBB78958     134 LTLPTISGLLtn------------------------sQLKRQTEDEYEQKRLERQYNDQLQQLKDEEERARVTVQLIDQA 189 Yarrowia lipoly...
OBA26354     162 IAVPTIKNFFqnlgpkyaplikkdssskiqydveqvpMINKRTPEEEELLALKREYNDNQRVIAKKIKNFNILFDLVSSS 241 Hanseniaspora v...
KKA03816     164 IVLPTIENIKqyltee---------------dreaypMVRTLTPAELEYEQAKEEINLLKAKKTEEITKMNLLQNLIKQL 228 Hanseniaspora u...
Feature 1                          
5MRC_VV      206 nEFIVTESQLLKKIDKVF 223 baker's yeast
KAA8910721   198 eNFIVTEQQLTHALNREF 215 Trichomonascus ciferrii
XP_024666444 198 rEYIITPEELDLAVDQQF 215 Wickerhamiella sorbophila
CDO51400     196 aNFITTEAKLKSAIEACF 213 Geotrichum candidum
XP_018738116 199 sNYVITEEDLDKLVQKEF 216 Sugiyamaella lignohabitans
ODQ67993     197 sKFIVTEEQLEEAIERAV 214 Nadsonia fulvescens var. elongata DSM 6958
VVT51857     216 sTFITTEEGLNAAIEAEF 233 Saprochaete ingens
VBB78958     190 dDFIVTEEQLIAGVEKAF 207 Yarrowia lipolytica
OBA26354     242 sKFITNEKQLAERLEEVF 259 Hanseniaspora valbyensis NRRL Y-1626
KKA03816     229 dGFILNEHQLSLKIEQEF 246 Hanseniaspora uvarum DSM 2768

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