Conserved Protein Domain Family
MCP1_TM

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pfam07950: MCP1_TM 
MDM10-complementing protein 1, transmembrane domain
This entry represents the transmembrane domains found in MDM10-complementing protein 1 from yeast, a mitochondrial protein involved in in mitochondrial lipid homeostasis.
Statistics
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PSSM-Id: 400346
Aligned: 71 rows
Threshold Bit Score: 36.9296
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_010756270 196 LASHVLVNRVVPLYVDG-GSSGVGLGFVAHGIARSPWL------MNLGYAAFVGVGVWHFAWGWAWWMGYKrevaetgkg 268
EMG45694      51 LGIHVTSVIIVPILP-IdQTIKDEIFSMGKAIYQSVPL--------YEPIFIIGSVSAHLLSGISlriyk---------- 111
Q5AGY8        51 LGIHATSVILVPILP-IdQSIKDEVFAMAKEVYQSVPL--------YEPICIIGSVAAHVMAGISiriyk---------- 111 Candida albicans
EDK46894      99 VGIHLTSVVIIPILP-IpRDVKDQVFSLAKAVYQDIPG--------YELLLIYGAGVCHILLGIIlrvvkv--------- 160
XP_001382525  31 VGIHLTSVVVVPLVPLVsADIKQEVFEMARAVYMSIPQ--------FENIVILGSSIIHVASGVAiriirs--------- 93 
XP_007377787  57 VGIHLTSVVIVPILP-IdTGIKQEVFSLAKAVYHALPL--------YETTIIYGSSLLHVISGVTlrvlr---------- 117
Q6FPG5        56 FPVHAVNTMITPLVNp--ETAPDSFLTAVHKW---VPQ--------AASKILIASLLTHIASGVLlrgw----------- 111 [Candida] glabrata
Q6CRQ5       169 LFFHGALMKWLPNTA----KVDIDFDFVKWLLDKDRGAlvriglGYGPLVALIGLGSYHIIAGTVQYMHVR--------- 235 Kluyveromyces l...
Q12106       184 LIYHLLIMKWVPNSI----STEVDFASIKQLLSSKNRWwkw-lgGLVPLAILLESGVYHIGSGLCRYFGVR--------- 249 Saccharomyces c...
Q6FPG5       171 VLYHLLIMKWVPESL---GEPATGFDFVKQLLRASEWWirw-faGIIPLSALISAASYHIVAGACRLLDVK--------- 237 [Candida] glabrata
XP_010756270 269 kgkrvgrstgpnggflgsfetggeFRRRSRKVRWIINGIAAVG--------------------AGLWLAGG------LGV 322
EMG45694     112 -------------------------kfftkK-----NNSTTSKtksvdspv-----rrlndhdDEIGF-GGlanlfgLGY 155
Q5AGY8       112 -------------------------kcfqkK-----PSHHINNgrhspit------nkledhdDEIGF-GGisnlfgLGY 154 Candida albicans
EDK46894     161 -------------------irrnrIEEKRRK-----AGSHVSKvhminsanlgngtidirdndEDIGL-GGisnlfgLGY 215
XP_001382525  94 ------------------ilrhnrEREKVQH-----RKSHVTTelit------------ddtrDDIGL-GGitnllgLGY 137
XP_007377787 118 --------------------tyerqQKKKNK-----KTGHFNMndsiq----------ikdsdDDIGL-GGissifgLGY 161
Q6FPG5       112 ----------------------------------klyKSHVLKekyhlhhq-----hkhttsqDDIGLTGGisg-ylFGI 151 [Candida] glabrata
Q6CRQ5       236 ------------------------SLKTRKR-------IMNFI--------------------LLLICTGY------IGI 258 Kluyveromyces l...
Q12106       250 ------------------------KMTSRKK-------WSTAI--------------------NLLTLVGF------VSL 272 Saccharomyces c...
Q6FPG5       238 ------------------------DMKKRKNASRII---------------------------SGLSIAGF------LSI 260 [Candida] glabrata
XP_010756270 323 VGREGL 328
EMG45694     156 RKSFtl 161
Q5AGY8       155 RKSFtv 160 Candida albicans
EDK46894     216 RRSItl 221
XP_001382525 138 TKSLvs 143
XP_007377787 162 KKSWis 167
Q6FPG5       152 YKQF-T 156 [Candida] glabrata
Q6CRQ5       259 SRLGSE 264 Kluyveromyces lactis
Q12106       273 IRLMKE 278 Saccharomyces cerevisiae S288C
Q6FPG5       261 LRLSNA 266 [Candida] glabrata
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