Conserved Protein Domain Family
ARE1

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COG5056: ARE1 
Acyl-CoA cholesterol acyltransferase [Lipid metabolism]
Statistics
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PSSM-Id: 227389
Aligned: 5 rows
Threshold Bit Score: 473.911
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1703371  106 SKEKARY-RQGSSNFISYFDDMSFEHRPSILDGSVNEPFKTKFVGPTLEKEIrrrekelmamrKNLHHRKSspdavdsvg 184 baker's yeast
19074639     --------------------------------------------------------------------------------     Encephalitozoon cun...
1703372    3 DTPRILItPSPLSDISTTINKPNVHPSMSLLKALPECRLVVKSKGDKNNANVvef-----pldRHKQLLIAg-------- 69  fission yeast
19076058   1 -----------------MIAATPAKSKPSDVN------LEQTFKGVSETSKI--------------DLRRS--------- 34  fission yeast
140500    96 SKSRSRFhRKDASKYVSFFGDVSFDPRPTLLDSAINVPFQTTFKGPVLEKQL-----------KNLQLTKTk-------- 156 baker's yeast
1703371  185 knDGAAPTTVPTAATSETVVTVETTIISSNFSGLYVAFWMAIAFGAVKALIDYYYQHNGSFKDSEILKFMTTNLFTVASV 264 baker's yeast
19074639   1 ------------------------------------------MRNNPSASPRNASSHSLSVHTTGRIHRGKSKIYGLKNL 38  Encephalitozoon cun...
1703372   70 --KVYHDYKFKPRKSIFDRVTDPNYFAKSEFRGFYVLFWLSMAAWVLQLYARSYWQR-DTLLGLPLARQVFRQFFVLFSS 146 fission yeast
19076058  35 ----RAAYRPLELSPTPSIFARNYQRNAVDFTGFFVLFWVAVSIMIFMSFLENFELTGRPVVG-TIFKYFQSNLLDLAKA 109 fission yeast
140500   157 -tKATVKTTVKTTEKTDKADAPPGEKLESNFSGIYVFAWMFLGWIAIRCCTDYYASYGSAWNKLEIVQYMTTDLFTIAML 235 baker's yeast
1703371  265 DLLMYLSTYFVVGIQYLCKWGVLKWGTTGWIFTSIYEFLFVIFYMYLTENILKLHWLSKIFLFLHSLVLLMKMHSFAFYN 344 baker's yeast
19074639  39 AVIIAFLSVGRFIIDNNREFGFLMSLPLQTLSLTECSCFLLTIFMSFVRSLLGFYIEARELGTLHICLNLGIFEVLVAYL 118 Encephalitozoon cun...
1703372  147 DFLMICLSFFSYGLQVCIEKNMIRWANLGYTIQTLWQGFYMV-LAVYWVKHRDFPIVQCVFFTLHCAVLIMKQFSYSHHM 225 fission yeast
19076058 110 DLAMSSMFLLAFPFQKIFALGYLRWYGLGVYLYSILILLFLS-HCVLRCCLSNWSWTHRAMFILHSMVILMKLHSYNVVN 188 fission yeast
140500   236 DLAMFLCTFFVVFVHWLVKKRIINWKWTGFVAVSIFELAFIPVTFPIYVYYFDFNWVTRIFLFLHSVVFVMKSHSFAFYN 315 baker's yeast
1703371  345 GYLWGIKEELQFSKSALAKYKDSINDPKVIG-------------------ALEKSCEFCSFELSSQSLSDQtq-kFPNNI 404 baker's yeast
19074639 119 NLKYIRHIYFSGWSMILDVVYIAKLIS----------------------------FHLVVWELRRDKKANT-----AGML 165 Encephalitozoon cun...
1703372  226 GYISEIRILHNEYEKLLKFVRECLNSTEKDEkytfeltfpnkpaetistlQAEEIVALTAKYLSRQMRSEVgnvvYPDNI 305 fission yeast
19076058 189 GWYSYCYHSLNKLQSKKTDLDDDER------------------------------SSVEFYEHCLNHHGNT----YPENL 234 fission yeast
140500   316 GYLWDIKQELEYSSKQLQKYKESLS-PETRE-------------------ILQKSCDFCLFELNYQTKDND----FPNNI 371 baker's yeast
1703371  405 SAKSFFWFTMFPTLIYQIEYPRTKEIRWSYVLEKICAIFGTIFLMMIDAQILMYPVAMRALAVRNS---EWTGILDRLLK 481 baker's yeast
19074639 166 RVRHFLYFLVVPTLCFQLDFPMKARRSTRDILLKTAQLLLGFLLFVLVMDQYAIPSIYRIVDFEDVt--------IVIEN 237 Encephalitozoon cun...
1703372  306 NFFNYVDYLLVPSLVYSMEFPRVAHFRWHYMAFKAGSTFGLLALTLALVDWYFVPSAVAVKDLDFIg--------KLRIA 377 fission yeast
19076058 235 TIPNALDFLFMPSLCYQLYYPRTAHVRIHYLIECALGTFGCIFLLVIISDHFMVPVLAKAIRTIIEapeDASATYFAIRL 314 fission yeast
140500   372 SCSNFFMFCLFPVLVYQINYPRTSRIRWRYVLEKVCAIIGTIFLMMVTAQFFMHPVAMRCIQFHNTp--TFGGWIPATQE 449 baker's yeast
1703371  482 WVGLLVDIVPgFIVMYILDFYLIWDAILNCVAELTRFGDRYFYGDWWNCVSWADFSRIWNIPVHKFLLRHVYHSSMSSFK 561 baker's yeast
19074639 238 IINLSISTII----LFLIFFYTVFYCFLDAVADITLFYDSCFYQEWWNASSAKEFWALWNRPVYLWFKRHVYTPMIS-RG 312 Encephalitozoon cun...
1703372  378 PLLMNKIMFP-AIILYLIMFYLIFDCILNAFAEITKFADRGFYGAWWNTVTWDEFSREWNKPVHVFLMRHVYHSSISGFK 456 fission yeast
19076058 315 GHTVAFLMFP-FMLSFLLVFWVIFEGVCNFSAEITRFADRNFYDDWWNCWTWDQFARTWNKPVHYFLLRHVYVPLN--SF 391 fission yeast
140500   450 WFHLLFDMIPgFTVLYMLTFYMIWDALLNCVAELTRFADRYFYGDWWNCVSFEEFSRIWNVPVHKFLLRHVYHSSMGALH 529 baker's yeast
1703371  562 LNKSQATLMTFFLSSVVHELAMYVIFKKLRFYLFFFQMLQMPLVALTNTKFMRNRTIIGNVIFWLGICMG--PSVMCTLY 639 baker's yeast
19074639 313 VSKEKAGLVIFTISGLVHEYVASISIKKATGWFLITMLLQVPLIHVTES-FKKRFPSLGNFFFWGAFCVIgqPSVMLLYY 391 Encephalitozoon cun...
1703372  457 LKKSHAVLLTFLISALVHEFVMLLATGKFRCYILTFQLLQIPLYDLQQMFAFKKRDILGNVFFWIGMFTG--PSFLCILY 534 fission yeast
19076058 392 MSKSLSTFFTFFVSSVLHELVMGCITLKIRGYGLFFQMTQIPYIIIQRQKFVRRHRLLGNIAFWFSIIIG--IALIAALY 469 fission yeast
140500   530 LSKSQATLFTFFLSAVFHEMAMFAIFRRVRGYLFMFQLSQFVWTALSNTKFLRARPQLSNVVFSFGVCSG--PSIIMTLY 607 baker's yeast
1703371  640 LTF 642 baker's yeast
19074639 392 RSL 394 Encephalitozoon cuniculi
1703372  535 IVF 537 fission yeast
19076058 470 ILF 472 fission yeast
140500   608 LTL 610 baker's yeast
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