Conserved Protein Domain Family
RAD4

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COG5535: RAD4 
DNA repair protein RAD4 [DNA replication, recombination, and repair]
Statistics
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PSSM-Id: 227822
Aligned: 5 rows
Threshold Bit Score: 487.436
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6321010    1 MNEDLPKEYFELIRKALNEKEAEKAPLSRRRRVRRKNQPLPDAKKK-----FKTGLNELPRESVVTVNLDSSDDGVVTVP 75  baker's yeast
19075054     --------------------------------------------------------------------------------     Encephalitozoon cun...
1723554    1 MMSDEDNTYSDDEEWLDLDLGLPNNDIKTAPILNSSLLSSAVHGERl----IQERPTHDFGDVEATVDRTVEKRSRLKIT 76  fission yeast
19075328   4 KRKASKNSVRGRKRRTRTNNLPLNPEVKEETVVSSTHRQTRSQSKKpslssSAEPPSESLDDNISALNSLQRSASSSEKG 83  fission yeast
6320520    2 AKRLLESSQNDQANRKNSKIEKKEVSFYEEEETDDSFDSFYQDEEDdl-sdIDWEEVSLDGSLTVTFGNIRRDREKVSKY 80  baker's yeast
6321010   76 TDDSVEEIQSSE-----EDYDSEEFED----VTDGNEVAGVEDISVEIKPSSKrnsdarrtSRNVCSNEERKRRKYFHML 146 baker's yeast
19075054     --------------------------------------------------------------------------------     Encephalitozoon cun...
1723554   77 SVDRKIRLQIHQ-----LHLLCLTYH-----LCTRNTWCDDNRLNYLVKYIPP----------GIRVSLHPSSQKSQMIR 136 fission yeast
19075328  84 SDEDNEKLGSSE-----DDEFDDDFDTweqvDLSPNKQEDKKDLHIVTQHITPqlt--kesKKGSSSAMDKSIRLSIHIM 156 fission yeast
6320520   81 KRKHNKKAFNYQrlkygLHLIMIPFMLf--lLKSRMKWIDDERLNRRLRRSVP--------KLIGKKFKDWDVRDPAFKM 150 baker's yeast
6321010  147 YLVCLMVHGFIRNEWINS--KRLSRKLS--NLVPEKVFELLHPQKDEELPLRSTRKLLDGLKkcmELWQKHWKITKKYDN 222 baker's yeast
19075054     --------------------------------------------------------------------------------     Encephalitozoon cun...
1723554  137 NKTFLHGLAGLVEVWKRKy-KITTNGLRk-PNYGLLQNNSLISESLSLEEFCKNSKLLSGSR---DYGTQLFASILRNLN 211 fission yeast
19075328 157 HFTCLLYHGSVRNRWLMN--SLLLDGLR--DLLVEKQPSVVEAWVCSSQTHEDLLKLLNGLR---MWWNKSFK-IESHGL 228 fission yeast
6320520  151 DSLRTLLLG--LVLWFRSnyKMNSNGIRqnFNRLQYLIKYADNQNENSISESTYKKVLENQQe--FYGNRPLINHGVEDI 226 baker's yeast
6321010  223 EGLYMRTWK-EIEMSANNKRKFKTLkrSDFLRAVSKGHGDPDISVQG----FVAMLRACNVNARLIMSCQPPDFTNMKID 297 baker's yeast
19075054   1 -----------MESSDSWEEATEDY---LEVVPCKRADIRRSADVRA-----EAIHRILWIFGKILAPVMRPVIEENVDL 61  Encephalitozoon cun...
1723554  212 VPTRLVFSL-QVLSFRFKGAINEAS--SHEIVPAWSQQMENDSSSD------ISESAHITSRFRKRRKIIQPSFSNLSHL 282 fission yeast
19075328 229 RKLGYRTLK-QGFDIGFSPEIFHNF--HEYQASLLSLKGSRDLAAQG----FTALCRSLNLKARLIFSLQPLTFSTASYD 301 fission yeast
6320520  227 RKMAKRKMAnRDILTLFFFIILENVlpGPKKLYLCFALPLHDYDIRCnkvkWQIEHGIGKVPNRFDSDLIQPYFWIELEV 306 baker's yeast
6321010  298 TSL------NGNNAYKDMVKYPIFWCEVWDKFSKKWITVDPVNLKTIEQVrLHSKLAPk--gVACCERNMLRYVIAYDRK 369 baker's yeast
19075054  62 HVD------EKLREYVNSLENIGEAGRVVILFKLLILFGIPSRIYIVLSEgIKCFVES------RILGAIREHHGRYNAC 129 Encephalitozoon cun...
1723554  283 DASdiv-teDTKLKVIDSP-KPVFWVEAFNKAMQKWVCVDPFGDASVIG--KYRRFEP----ASSDHLNQMTYVFAIEAN 354 fission yeast
19075328 302 DWSphilpeETSTSIDDDLRYPIFWTEIYDQSEKKWIAVDAVVLNGVYTN-DMTWFEPkgayAESKHL-RMGIVAAYDND 379 fission yeast
6320520  307 PTLs-----DGELYIIDPIAHLGEREMVLKTREDQFVPTYQPSVDMKYN--LNQKFHY------VVRINHAEKVLQDVSP 373 baker's yeast
6321010  370 YGCRDVTRRYAQWMNSKVRkrRITKDDFGEKWFRKVITALHHRKR--TKIDDYEDQYFFQRDESEGIPDSVQDLKNHPYY 447 baker's yeast
19075054 130 VVSVDASLRLRDQSYYFSK---STRHLASVQYVVRQFPGPDVCGEa-SSEEMTRCFDDLDERRMSKIPTSVEKMKRHPKF 205 Encephalitozoon cun...
1723554  355 GYVKDVTRKYCLHYYKILKn-RVEIFPFGKAWMNRIFSKIGKPRDfyNDMDAIEDAELLRLEQSEGIPRNIQDLKDHPLF 433 fission yeast
19075328 380 LYAKDVTLRYTDYQSSRLK--KIRHVSFADKYFDFYKAIFGQLAKrnKDAEDIYEEKELESKVPIREPKSFADFKNHPEF 457 fission yeast
6320520  374 RYVPNVCYRYFELSESSPI--LKSKHYTSYQYLSKWLKVLNKKKAs-VHHYAIMKKIALTN---FTLPKSVTEIKRTDNF 447 baker's yeast
6321010  448 VLEQDIKQTQIVKPGcKECGYLKVH--GKvGKVLKVYAKRDIADLKSARQWYMNGRILKTGSRCKKVIKR----TVG--- 518 baker's yeast
19075054 206 IVESILRWDQCIYPK--RPTFGLFK--G-----EAIYLRENVVRLRTREQLYRMGKVID-SPKPYRIVRR---------- 265 Encephalitozoon cun...
1723554  434 VLERHLKKNQAIKTG-KSCGRINTKn-G----VELVYPRKYVSNGFSAEHWYRKGRIIKPGAQPLKHVKN---------- 497 fission yeast
19075328 458 VLIRHLRREEALLPN-AKPVKTATFgnGKkATSEEVYLRKDVVICKTPENYHKEGRVIKEGEQPRKMVKAravtISRkre 536 fission yeast
6320520  448 VIPSLLKSNEVLKAC-AKQAATFTK--GD-NSQEPIFWRRDVIQLKSKQHWAILGRSILPNAQPLKRKKYl--pMREr-- 519 baker's yeast
6321010  519 ---RPKGEAEEEDERLYSFEDTEL-----------YIPPLASASgEITKNTFGNIEVFAPTMIPGNCCLVENPVAIKAAR 584 baker's yeast
19075054 266 ---------DKEIR-LYAPWQTRD---------------LVVEG--FCESMYQ--DYLHPNFIPRDCVYIDNKNARDVAR 316 Encephalitozoon cun...
1723554  498 --------GDKVLP-LYDEEATQL-----------YTPKPVVAN-IVPKNAYGNIDLYVPSMLPYGAYHCRKRCALAAAK 556 fission yeast
19075328 537 hefRVAETNEPVLQGLYSSDQTEL-----------YVPPPIKDG-IIPKNGYGNMDCFVESMIPKGAAHLPYRGIAKIAK 604 fission yeast
6320520  520 ---MVRNLDKYVIKELFSYEQTMKspkypstycdhLGQEHVITDlSHYKNKFGNIEIYSKETKPDGFELIPLSKEVDIKC 596 baker's yeast
6321010  585 FLG-----------VEFAPAVTSFKFERgSTVKPVLSGIVVAKWLREAIETAIDGIEFIQEDDNRKEHLLGALESWNTLL 653 baker's yeast
19075054 317 LLG-----------LPHRICFHGFSRGV-----PVNRGIFLEKKNLYVFSNFLAQYCRYLEMKERSECRSMGLKRWRILI 380 Encephalitozoon cun...
1723554  557 FLE-----------IDYAKAVVGFDFQR-KYSKPKLEGVVVSKRYEEAIDLIAEEIDQEEKEAEARNVRKTCLLLWKRLI 624 fission yeast
19075328 605 KLN-----------IDYADAVTGFEFRK-HRAIPVTTGIIVPEESAQMVYEEFLECEKIRIEKQQMKERKIIYGQWKHLL 672 fission yeast
6320520  597 LIKeynkgkrkmqkIKYLDVVSGFDFKQ-----K--KGHAIPK--IESILVKETDYKAVQLLKQQTKVLLG-LSFWDILL 666 baker's yeast
6321010  654 LKLRIRSKLNSTYGKI 669 baker's yeast
19075054 381 RNASRYLRIRKSLGLK 396 Encephalitozoon cuniculi
1723554  625 TGLRIRQRVFEEYG-- 638 fission yeast
19075328 673 NALRIRKRIEEQYA-- 686 fission yeast
6320520  667 RKLRVNDRLNAEYGNV 682 baker's yeast
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