6IC4


Conserved Protein Domain Family
MlaE

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pfam02405: MlaE 
Permease MlaE
MlaE is a permease which in E. coli is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. In Swiss:Q7DD59 it is involved in L-glutamate import into the cell. In Swiss:Q8L4R0 it is involved in lipid transfer within the cell.
Statistics
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PSSM-Id: 460549
Aligned: 619 rows
Threshold Bit Score: 85.1566
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6IC4_G               41 FVYQMHRVGVMSLLIITVSGLFIGLVLGLQGYSILVNVGSESMLGTMVSLTLLRELAPVVAALLFAGRAGSALTAEIGSM 120
WP_013705132         60 FARQIYLIGGRGWPIVALTGMLLGLAIIVYASAQLAKIGGEQFVGNLLVIIVIRELGPVLTALLVLLRSGAAMIVEIGGM 139 Desulfob...
WP_012173462         48 VVEQIYFTAVQALFLIIPLSLLTGSMMLIQFA----KFSGQVDLGKLMIILVIREIGPVVTAMLVVLRSATAVTIEIGYM 123 Desulfos...
jcvi:TREAZ_3364      41 LIMQILFTFVEALSISTLLALGIGAAVNVIGIPFLAQFSQEAYIYPLLITIITRELGPLLTAFIIIARSATAIATEMAGM 120
jcvi:TREPR_0796      39 ltLQILFTFVEALGIASLLALGIGAAVYVIGMPLLLNLSQPRLIYSLLIIIITRELGPLLAAFIIIARSATAIATEIGGM 118
jgi:Ctha_2170        50 LLRQVLFTGYEALSIVVLISVSIGGLIILEGYSILANFGQSDLLYVILVSVITRELSNLLTAFIIVARSGTAIATELGNM 129
WP_015425085         37 VIRQILFTGVEALPLIGFIALAIGCLTIMQGYAFLSNFGQGIWVHIILVRVVVGELSGIITALVVIARSGTAISTELGNM 116 Candidat...
CBK41244             77 LVRQILFTGVDALPVTTVIALLLGIIIVTQAGTQLPRLGAGGLVGSIIVVTVIRELGPLITAFIVVGRSGTAIATELGNM 156
BAM06898             45 LLQQILSIGFDAIPILTIVGLLLGMGTVAEAGLELPKLGIQNLVGTIIIHIILRIVGPFATAMVVIARSASAISVEIGNM 124
SDU_Lin:LFML04_1382  45 FLNQILFNGLDALPILTVVSFLVGMGTVAEAGIELPKLGVQNLVGPIILHIILRIVGPFTTALIVTARTASSLTVEIGNM 124
6IC4_G              121 KQSEQLASMEMIGVDPLKQIVSPRLWAGIVSLPMLTVIFAAIGIVGGKLVGVD--FLGVDEGSFWSGMQNNVQFGhDVVN 198
WP_013705132        140 VLEREIEALELMGLEPEIVIGGPRFWGLVISLITLYFIFVVCAVWGGFLFSQI--FADMYWGVFWLSFVNALGWP-DLVL 216 Desulfob...
WP_012173462        124 NVFNEIDSLEMTGIDPLRLLAIPRFVGITSAIVCLFIVFDLVAILGGY--GVVrlTTSIPVGNFLSDIGSAITGA-DIIV 200 Desulfos...
jcvi:TREAZ_3364     121 VISHEIEAYISVGVDPIEYLAVPRFLGVTISLFMLNIFFSVFGLAGSFAVAQI--FNPMPASVYFGNILLSLSLP-DIIV 197
jcvi:TREPR_0796     119 VISHEVEAYIAVGVDPIEYLAVPRFLGVTVSMFLLNIYFSVFGLAGSYGVVRI--FNPLPAEYYFSSLFQALTIH-DISI 195
jgi:Ctha_2170       130 VVNHEIDALLSIGISPISYLVVPRTIGVVVSLLVLNVYFNITGILGGWMVSNW--FYPIDFNVFFSKLLAKLTLV-DISA 206
WP_015425085        117 VVNREMQLLKSFDIAPMGYLVVSRILGVVISMLVLTLYFNIIAVLGGWLFAQF--FNHLSFGAFMNDFLSVLTFP-YILM 193 Candidat...
CBK41244            157 SVTREVVALRLMGISISRFVIMPRMVGMVLSMLCLTLYFDVVAVLGGYLIADA--QLTIPFYAFVESITKALSTT-DVLM 233
BAM06898            125 RVSGELDTIEMLGVNLSFFLITPRIVGVLISMMALTFYFAICSFTGGFLMGLF--GLSMPMVSLIESLKTSLTLS-DLLV 201
SDU_Lin:LFML04_1382 125 RISGELDTIEMMGANISYFLLAPRLFGAIVSTVALSLYFAVIAFIGGLLIAFF--GLSMPIVSLIRALETSINLP-DLLI 201
6IC4_G              199 GIIKSIVFALLCTWIAVFQGYACDPTPEGIATAMTRTVVYSSLCVLGFDFVLTAV 253
WP_013705132        217 NFAKVVLFGMFIGVVAIYHGLQTADHWESIVAQTSRGAVISLLFLGLINTALSVL 271 Desulfobacca acetoxidans
WP_012173462        201 GLVKALCFGVVISVVTLYHGFEAQKRITVIPKITSTAAIECFFYCIVTNIFISGL 255 Desulfosudis oleivorans
jcvi:TREAZ_3364     198 SVIKSITFGIIISVVAIVKGLAVERSSTEVPIAGLKAVGASFGWCILVDILLSAL 252
jcvi:TREPR_0796     196 SIIKSICFGMIIAVLAISNGFSVERASTEIPIVGLKSVGSSFAWCIIVDILLSAL 250
jgi:Ctha_2170       207 SILKSMLFGFAIAIISSFHGLQVNFASTEVPQRTIRAVVYSLTMVVIIDVAVVVL 261
WP_015425085        194 TILKSVIFGFVIAITASYEGMSVYRASTEVPQRTIKAVVISIFSVLILDLIISWL 248 Candidatus Cloacimonas acidaminov...
CBK41244            234 TAIKGLSFGSAVAAICCYHGLAVRSSFTEVPQQTTRAMINSFVLCLLIDVVVTVp 288
BAM06898            202 PLMDSAAFGLIIAAVAVYHGLSVGQSPNDVPRETNKALVNAIVLCTLVLTVIQIF 256
SDU_Lin:LFML04_1382 202 PLVESITYGSIIAAVGSYHGLKVGDSPTDVPQQTTRALVSSIVLCTLFSTFFLvf 256
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