1K3C


Conserved Protein Domain Family
pckA
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TIGR00224: pckA 
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phosphoenolpyruvate carboxykinase (ATP)
Involved in the gluconeogenesis pathway. It converts oxaloacetic acid to phosphoenolpyruvate using ATP. Enzyme is a monomer. The reaction is also catalysed by phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) using GTP instead of ATP, described in PROSITE:PDOC00421 [Energy metabolism, Glycolysis/gluconeogenesis]
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Statistics
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PSSM-Id: 161774
Aligned: 5 rows
Threshold Bit Score: 926.198
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1K3C_A   3 VNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPsltgyERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTF 82  Escherichia coli BW2952
P43923   2 TDLNKVVKELEALGIYDVKEVVYNPSYEQLFEEETKPglegfEKGTLTTTGAVAVDTGIFTGRSPKDKYIVLDEKTKDTV 81  Haemophilus influenza...
P54418   1 MNSVDLTADLQALLT--CPNVRHNLSAAQLTEKVLSR-----NEGILTSTGAVRATTGAYTGRSPKDKFIVEEESTKNKI 73  Bacillus subtilis sub...
P10963  13 TSEVEQKIRQELALSDEVTTIRRNAPAAVLYEDGLKE-----NKTVISSSGALIAYSGVKTGRSPKDKRIVEEPTSKDEI 87  Saccharomyces cerevis...
P22259   3 VNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPsltgyERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTF 82  Escherichia coli K-12

1K3C_A  83 WWADKgkgkndN------KPLSPETWQHLKGLVTRQLS-GKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRP 155 Escherichia coli BW2952
P43923  82 WWTSE------Takn-dnKPMNQATWQSLKDLVTNQLS-RKRLFVVDGFCGASEHDRIAVRIVTEVAWQAHFVKNMFIRP 153 Haemophilus influenza...
P54418  74 DWGPV------N------QPISEEAFERLYTKVVSYLKeRDELFVFEGFAGADEKYRLPITVVNEFAWHNLFARQLFIRP 141 Bacillus subtilis sub...
P10963  88 WWGPV------N------KPCSERTWSINRERAADYLRtRDHIYIVDAFAGWDPKYRIKVRVVCARAYHALFMTNMLIRP 155 Saccharomyces cerevis...
P22259  83 WWADK------GkgkndnKPLSPETWQHLKGLVTRQLS-GKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRP 155 Escherichia coli K-12

1K3C_A 156 SDEELAGF-KPDFIVMNGAKCTnPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLP-LKGIASMHC 233 Escherichia coli BW2952
P43923 154 TEEQLKNF-EPDFVVMNGSKVTnPNWKEQGLNSENFVAFNLTERIQLIGGTWYGGEMKKGMSSMMNYFLP-LKGVGAMHC 231 Haemophilus influenza...
P54418 142 EGNDKKTVeQP-FTILSAPHFK-ADPKTDGTHSETFIIVSFEKRTILIGGTEYAGEMKKSIFSIMNFLLP-ERDILSMHC 218 Bacillus subtilis sub...
P10963 156 TEEELAHFgEPDFTVWNAGQFP-ANLHTQDMSSKSTIEINFKAMEMIILGTEYAGEMKKGIFTVMFYLMPvHHNVLTLHS 234 Saccharomyces cerevis...
P22259 156 SDEELAGF-KPDFIVMNGAKCTnPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLP-LKGIASMHC 233 Escherichia coli K-12

1K3C_A 234 SANVGEK-GDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLEN 312 Escherichia coli BW2952
P43923 232 SANVGKD-GDVAIFFGLSGTGKTTLSTDPKRELIGDDEHGWDDVGIFNFEGGCYAKTIHLSEENEPDIYRAIRRDALLEN 310 Haemophilus influenza...
P54418 219 SANVGEK-GDVALFFGLSGTGKTTLSADADRKLIGDDEHGWSDTGVFNIEGGCYAKCIHLSEEKEPQIFNAIRFGSVLEN 297 Bacillus subtilis sub...
P10963 235 SANQGIQnGDVTLFFGLSGTGKTTLSADPHRLLIGDDEHCWSDHGVFNIEGGCYAKCINLSAEKEPEIFDAIKFGSVLEN 314 Saccharomyces cerevis...
P22259 234 SANVGEK-GDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLEN 312 Escherichia coli K-12

1K3C_A 313 VTVRED-GTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKL 391 Escherichia coli BW2952
P43923 311 VVVRSD-GSVDFDDGSKTENTRVSYPIYHIDNIVKPVSRAGHATKVIFLTADAFGVLPPVSKLTPEQTKYYFLSGFTAKL 389 Haemophilus influenza...
P54418 298 VVVDEDtREANYDDSFYTENTRAAYPIHMINNIVTPSMAG-HPSAIVFLTADAFGVLPPISKLTKEQAMYHFLSGYTSKL 376 Bacillus subtilis sub...
P10963 315 VIYDEKsHVVDYDDSSITENTRCAYPIDYIPSAKIPCLADSHPKNIILLTCDASGVLPPVSKLTPEQVMYHFISGYTSKM 394 Saccharomyces cerevis...
P22259 313 VTVRED-GTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKL 391 Escherichia coli K-12

1K3C_A 392 AGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNG----TG-KRISIKDTRAIIDAILNGS 466 Escherichia coli BW2952
P43923 390 AGTERGITEPTPTFSACFGAAFLTLHPTQYAEVLVKRMQAAGAEAYLVNTGWNG----TG-KRISIKDTRGIIDAILDGS 464 Haemophilus influenza...
P54418 377 AGTERGVTSPETTFSTCFGSPFLPLPAHVYAEMLGKKIDEHGADVFLVNTGWTGggygTG-ERMKLSYTRAMVKAAIEGK 455 Bacillus subtilis sub...
P10963 395 AGTEQGVTEPEPTFSSCFGQPFLALHPIRYATMLATKMSQHKANAYLINTGWTGssyvSGgKRCPLKYTRAILDSIHDGS 474 Saccharomyces cerevis...
P22259 392 AGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNG----TG-KRISIKDTRAIIDAILNGS 466 Escherichia coli K-12

1K3C_A 467 LDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPE-QWQEKAETLAKLFIDNFDKYTDTpAGAALVAAGPKL 540 Escherichia coli BW2952
P43923 465 IEKAEMGELPIFNLAIPKALPGVDSAILDPRDTYADKA-QWQSKAEDLAGRFVKNFVKYATNeEGKALIAAGPKA 538 Haemophilus influenzae Rd ...
P54418 456 LEDAEMITDDIFGLHIPAHVPGVPDHILQPENTWTNKE-EYKEKAVYLANEFKENFKKFAH--TDAIAQAGGPLV 527 Bacillus subtilis subsp. s...
P10963 475 LANETYETLPIFNLQVPTKVNGVPAELLNPAKNWSQGEsKYRGAVTNLANLFVQNFKIYQDR-ATPDVLAAGPQF 548 Saccharomyces cerevisiae S...
P22259 467 LDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPE-QWQEKAETLAKLFIDNFDKYTDTpAGAALVAAGPKL 540 Escherichia coli K-12
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