Conserved Protein Domain Family
LpoA

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COG3107: LpoA 
Outer membrane lipoprotein LpoA, binds and activates PBP1a [Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 442341
Aligned: 136 rows
Threshold Bit Score: 350.419
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_121814433   1 MVPSkfir----------------------------------------------------skagRCLPVVLA------AL 22 
WP_011576417   1 MKLI------------------------------------------------------------RSVVVVSL------VV 14 
WP_014950519   1 MRHIgqa------------------------------------------------------gkiFTLSAVAS------VL 20 
WP_013754689   1 MKLI------------------------------------------------------------RSVVVVSL------VV 14 
WP_007639905   1 MRFR------------------------------------------------------------TFVVFCVA------IL 14 
WP_082633313   1 MLNM------------------------------------------------------------RKLTILIA------VL 14 
WP_068544897   1 Mirks--------------------------------------------------------islKYSIVIVT------LL 18 
WP_115720001   1 MTRIl----------------------------------------------------------sRSAGLLCL------AL 16 
WP_117317704   1 MGVGtmykvawsailtwsvnvkgqkcntpyglfiapaidfpvcsdklgyqlvklaqkdscvyqaSPLKLLLKcgffagAL 80 
WP_127025924   1 MFLSlylciv-------------------------------------------------kssklKPLILLGS------AI 25 
WP_121814433  23 FFAGCtTt--------------KAP--DQ----STAH---------M---QGEATADSAYYLQQMQ----QSAD-DSKTT 65 
WP_011576417  15 FMASC-Adtpnk------knavKRP-----------D---------IkvvQPDRELNSQYYLNQAQrqfaETGDtTQRNR 67 
WP_014950519  21 VLTGC-Gstp---------ktqSKPvv----vePTP----------IettQVEDNVTPEHKLLEAKkvweRTRNkEQRDT 76 
WP_013754689  15 FMASC-Adtpnk------khtvKRP-----------D---------TkvvQPDQELNSQYYLNQAQrqydASGDiTQRNS 67 
WP_007639905  15 CLLSC-Asns----------trQSPktl---vsPSEK---------It----EEAKDSNYYLTRAQqnyvNNADvYQRNN 67 
WP_082633313  15 LLTAC-AtapdvsdkgvdtryrTVP-----------E---------I-----PAERTAEQLYAQAR----QA-PlHQQPL 63 
WP_068544897  19 TLYGC-Atpekk------ktdtTTPt-------SAIEtv-----evIe-dSTDSEITAEDLVEQAS----SEDN-EQAIV 73 
WP_115720001  17 LLSSC-Attaqkd---nwtarlTSP---------------------V-------SLKANQYLDKAR----QSEG-EDKLL 59 
WP_117317704  81 VLTAC-Ssptv--------qrsSVPa------qPAPQ---------Ve--EKIVTLSADALIRQARevwqERADkIQRDA 134
WP_127025924  26 ALASC-Sstp----------eqTAPvkRAplvkPAPqaeeeveivkI-----AKPLSGADFIEQAG----QQQG-SEQQW 84 
WP_121814433  66 WQLLAIHALVKEGKTQQAVDLYNQLPKE-MNDEQRREQQLLVPE--IRVAQKDYAAANAALAKINPaELSKNQQARYYQS 142
WP_011576417  68 LILQAASVLQQEDNCNASIKLLNILTPElIHPDLQSEAQLLLAQcyMQLPTPAVSQAQKLVNKLLKs---KHESAQLSEL 144
WP_014950519  77 LLLQAADLYLQNQQPVLAQQVLYEVKEDgISGVNQSYYALLVTKayAGMPDASAEELLAMLDGVTGtg---eTAFQKAEL 153
WP_013754689  68 LLLQAAASLQHEKNCNASIKLLNILTPElIHPDHQPQAQLLLAQcyMQLPTPAVAKAQKLMTRLSKs---QQDPAQISAL 144
WP_007639905  68 YLIQAAESLQAEQQCPKSIKLLKVLQAElQDNRHYTHANLILAEcyLILSDKTFHKVEAILTNLTGa---YGYQARIAAL 144
WP_082633313  64 LLLQAVMVWQQQGDCQSALKVLQPLIPElRDATQRDQARLIRSQ--CLLELDKPALASASLEKVSNn---IHILPARLKL 138
WP_068544897  74 LLLQATNKYIQQQQLDKALSMALELRKLsLTNAQENYNQLNISE--VLFEIGEIELASQELSKVNTq----tVSKRQLFL 147
WP_115720001  60 WQLQAARAYAQAGDWARTNDVLQALKGQlTSPAAQHAYTLLAAE--SALAHENYDKAAALLKTPMTg----rFEIQRLRL 133
WP_117317704 135 LLLDAATAYLQEDDHKRARKLLLMLNKTgLAPSQQATANTLLAQsySDAPDANPQALIDLLLPLAEnp---eLQARQRRI 211
WP_127025924  85 QLLEAAKAHLQQGEIEQALAISRVLAQQ-AAPEVQQANLLAFFQ--GLVAAGDHEDIEKFSSQYSLrSFRAEDKAAYLQS 161
WP_121814433 143 VIDASQNRAS-LELLRAYIAQEPILT-G-PAHQKNIDGTWQALSQMTPEQMNSLVINADENTLQGWLDLQRVWNDNRNDP 219
WP_011576417 145 QALIDEQQHAwLAASENLLA-------AgNLNQENSLRLWRAIGNLTNKQEKQAVI--DEPRLKSWIELKTIIQQLGTQP 215
WP_014950519 154 QTQLFTQQGNlAAAANSVLKTN-------LTDDEKVQQVWQWITSIPASSLDSVGS--AYPDLSPFITLRELTEENASSP 224
WP_013754689 145 QARIDEYQHAwLAASENLIA-------AgNLDQEHSLRLWHAIGNLTSKQDKQAVI--NEPRLKSWIELKTIVQQQGTHP 215
WP_007639905 145 QSQLHVNKKQwLEAAIALQN-------TnMEELDKTRTIWEWIKALDLPELENARL--SEPSLQPWLQLAIIVKRFALKP 215
WP_082633313 139 SAELAEYHRQyLNAARSHAELISL---DpSRAESGYRKIWQLLEQVDNKDLPEVAA--QPGYLAPWLELARITRTV--PG 211
WP_068544897 148 QANINVQTGMlINGIIDYLNYHQQYPiTa---EDEAFYLATLFAKLKPYQVTALSKR-KALHLEGWLAYTSSLSEY-GNA 222
WP_115720001 134 AAQLAELAGNtEDELNALAKLAALTD-DqTLKARTSDRIWALLAQADTDNL--------GPDWAPWVTLQQLAREK--RG 202
WP_117317704 212 LTELYEKQADyLAAANNYVQIM-------TPSGASVERVWRWINQTPVEALSDAAQ--TYPALQPYLSLHQLLARHGLNS 282
WP_127025924 162 LAQYQSSRREpDKAVNTYLQLLTLQ----PEQTQYQSALWQQLGMLTPDQLEKVRQ-SSDPTAQGWAQLLQLHQQHLGNT 236
WP_121814433 220 EMLKAGIKDWQTRYPQNPGAKTLPTQLSNMQN-YKAASTNKIALLLPLSGQAAVFGRTIQQGFEAAKNMGSAPVaqstap 298
WP_011576417 216 QRLKVQVNQWQNKHSSHPLSEVLPEALVNAME-QDTITPKRVAVLLPLTGRLSSQGNAIKDGIIAAYLAHLNSAstsns- 293
WP_014950519 225 EKLAKSLQQFKQVYRGHVLENALPENVIEATQ-LTDAGANDIAVLLPLSGRLARTGQVVKNGIMAAYYTDVEKRqd---- 299
WP_013754689 216 EKLKTQVNQWQAKHASHPLANLLPDTLLSAMA-QKAISPKRLAVLLPLTGRLASQGNAIKDGVVAAYLAQLNEPagfsn- 293
WP_007639905 216 EMFNQQLVSWQSRHLGHPLVINLPEEIQFSLQ-QEPIQAKRIAVLLPLTGRLANQGLAIKEGILAAYLEDLPNAkftsnn 294
WP_082633313 212 VELSQRINLWQQQYPDYSL----PEPVQQMLQ-QAHYQPQNIAVILPLSGRLANQGQALKEGILAAYFDTSQPRe----- 281
WP_068544897 223 DDITNQLATWQSKFPEHPANLLIANVQQQAITlEQDAEFETVSVLIPLSGREKTLGETIQAGIMAAYQQK---------- 292
WP_115720001 203 PALETAIGNWRELYPQSLPAQYLPQSLEKLTK-VVDYTPTKVALLLPLTGDYSAQGRAIRDGFVSAWVASg--------- 272
WP_117317704 283 QALTAELNQFRQVYRGSALVEFLPEEVTQASR-LTSVRITKAAVLLPLSGRFAATGKAIKEGILAGYYARTGQDss---- 357
WP_127025924 237 PALTQAISDWQQQYSNLPSLQQLPAEIQQLSA-VDAFSPQTIAVLLPFSSNFRQHAEAIQQGILAASAn----------- 304
WP_121814433 299 attpdtnaqpvdttqaalpqptdanmvaspsaasvddltqqpaadaaqptpvpqsapqvqsaatapanPSAEIKVYDTTT 378
WP_011576417 294 ----------------------------------------------------------------qastQNIELQFFDSAL 309
WP_014950519 300 ------------------------------------------------------------------ehLLPRLRFIDTNE 313
WP_013754689 294 ----------------------------------------------------------------estlTNVELQFFDSAL 309
WP_007639905 295 ssdydg---------------------------------------------------atgniaqdnvqQYREIRFFDSAL 323
WP_082633313 282 --------------------------------------------------------------------HKTQLTFYDSVV 293
WP_068544897 293 --------------------------------------------------------------------SKVQLNFIDTNA 304
WP_115720001 273 --------------------------------------------------------------------QSAQLVVLDSAK 284
WP_117317704 358 -------------------------------------------------------------------gFAQQLKFIDTNN 370
WP_127025924 305 --------------------------------------------------------------------QQARLIFIDSQT 316
WP_121814433 379 QPLAQILAQAQQDGATIVVGPLLKNNVDELANST------------------------------------S--------- 413
WP_011576417 310 KIPEELSEQVTD--YDTIIGPLLKEKIAQLIALL------------------------------------Pa-------- 343
WP_014950519 314 VDTQHLLSEIGD--TKFIIGPLLKDTVERLIPSL------------------------------------Pl-------- 347
WP_013754689 310 KTPEELKALVAD--FDVIIGPLLKEKIAKLITLL------------------------------------Pe-------- 343
WP_007639905 324 KTAQQLNTLVAD--FDVVLGPLVKEQITELTEVL------------------------------------Ps-------- 357
WP_082633313 294 LDETEIQTLALQ--HDFVLGPLIRENIPAILSQL------------------------------------Pq-------- 327
WP_068544897 305 TNMSDIVANLHQQKPSFVIGPLLKQHVESYLASThdetafdegsvemttisaennnpfteseaitesaqsSdqlslqeql 384
WP_115720001 285 -GAVAAWQQAQAQGADMLVGPLLRPQIEALQQAN------------------------------------Sv-------- 319
WP_117317704 371 KTAEQLASAVGD--TKWLIGPLLKENIEGLLPLL------------------------------------Ap-------- 404
WP_127025924 317 -DTAALKQQLAAEQVDFVIGPLLREQVDVISQQA------------------------------------Dw-------- 351
WP_121814433 414 --P--LNILALNQPEKV-----------------------------------------------QNRA------NIC--- 433
WP_011576417 344 --N--KSVLALNRIDSIienkttdntlvdniivdqa---------vpaenitlpdvnnafetlpAASP------EVF--- 401
WP_014950519 348 --G--VNVLALNRPDELpdnasakglatgssnpaiadd------alasgtglagddtqnelhslGLPT------SLN--- 408
WP_013754689 344 --D--KSVLALNRIDSIvsnmpashlvdsnqsladsaentaaseslplqvqsqqdadlsdampqNKAP------EVY--- 410
WP_007639905 358 --D--KILLALNRVQLKtktitinq-------------------------------lgnlfepsSPVA------EHY--- 393
WP_082633313 328 --S--TPALLLNRLEQE-----------------------------------------------EVSP------HRY--- 347
WP_068544897 385 tlPhqWPTLLLNLPEQN-----------------------------------------------VLNK------NQF--- 408
WP_115720001 320 --K--VPWLALNRVYRPgf------------------------------------------------------gDDY--- 338
WP_117317704 405 --D--THLLALNRVDLLpqa------------------------------------------siSASAqalipeDLYian 438
WP_127025924 352 --T--IPTLFLNGKTDLv----------------------------------------------QQSA------DKF--- 372
WP_121814433 434 -------YFALSPEDEARDAAGHIWQQGHRAPLLLVPRNALGDRVTKAFAEEWMKLGGGT-------VLQQKFGSVAELK 499
WP_011576417 402 -------YFSLAPEDEAIQLAKHIHDLGLRHPIVLAADTSTTQRMSEAFIQQWQQNDQQQdy---vvPATGTFTDSKNMR 471
WP_014950519 409 -------YYGLAPEDEAKQLAEFIFNKGYRAPIVIAAQSSLYQRMDDTFKKHWRILNNQEnkq-ranITSVSFNDSNSLR 480
WP_013754689 411 -------YFSLAPEDEAIQLAKHIHTLGFRHPIVLAADTSTTQRMSEAFIKQWQHNAQQQdy---vaPANGTFTDSKNMR 480
WP_007639905 394 -------YFSLAPEDEAQQLALHMQQKQLVRPIVFAANNPTTQRMAEAFVAKWQEAPNAIq------PDLTIFTDSKNMR 460
WP_082633313 348 -------FYSLAPEDEAEQLASYLYANGYRRPVLISAKRQLFERMAEHFMRRWQTLDKSE-------PSLMTFTDNKSMR 413
WP_068544897 409 -------ALSMLPEDEARQAAFSLSQKGYQQAMVLSQNSTIGKRMAKSFADEWQKYHHTQ-------VNIIYYPNGKEMQ 474
WP_115720001 339 -------FFALAPEDEAAQAAEEAVDRHARHPMLLGLDTNTNNRQAQAFIQRWRQYGHDEp------VDMRLFANQQQLE 405
WP_117317704 439 llpkyaaWFALAPEDEAYQLADEIFAKGYRSPIVVAADGAIYQRLLDAFQQRWQAQVKQTgrtqgheLDVVRYTDSASLK 518
WP_127025924 373 -------YFSLSVEDEAHQMAMLFKQKNYKQPVLMASRNPLSQRMAEQFGRDWKQIAGKE-------PEVYWFADQAGME 438
WP_121814433 500 QGINSGSGIALTGSPVTPASAqpegvtiGGLTIPPpptdaqiTAGTSGGVDAAYIVATPDEVALIKPMIAMRtgsRSP-- 577
WP_011576417 472 KLVSELLDVAQSRQRMKQIELl------TTSEVYA-------VERNRRDVDAIILFANPEQTELLNPIIESSlspFAAre 538
WP_014950519 481 EGITQALDVAQSNERINQIEYm------TNDEVYN-------MPRSRRDIDAIVAFASPQDTELLNPIIEASlnpYDGkq 547
WP_013754689 481 KLVSELLDVAQSRQRVRQIELl------TTAEVYA-------VERNRRDVDAIILFANPEQTELLNPIIESSlspFAAre 547
WP_007639905 461 NRVSEMLDVAQSKQRIRQMEVl------ADVEVFG-------VERNRRDIDAIVLFANPEQAQLLNPIIEASlspFAQks 527
WP_082633313 414 DAVDSLLDIQQSERRINQLQRl------VNKEIHS-------FARNRRDVDAIVVFSNPAQTELLNPMIESSispFASi- 479
WP_068544897 475 TAVKRGLEVNLSDERIYLMRNr------ISENVKA-------EARNRRDVDMIYIFGTPDQARLIKPYVDVNispFAEs- 540
WP_115720001 406 AGIRSQLQIDDSKARIRQVEAv------LGRKVVA-------EARSRRDVDFMYLMGDREEVGLMKAFIDVTispFADp- 471
WP_117317704 519 EGITESLGVAQSKTRIDQIRYm------VNEKLHN-------VTRNRHDIDAIVVFASPEQTELLNPMVEASlspFDGkt 585
WP_127025924 439 STIKQLLETAASEQRIREISQl------AGESVKA-------EPHSRQDIDAIYLLADPSQTRLLKPYIDVSvapTKTt- 504
WP_121814433 578 AQLYASSRSSQGVNGPDFRLEMDGLQFSEIPMLAGNN---PSMMQQALSNV-HNDYSLARLYAMGVDAWSLANHFSQIRQ 653
WP_011576417 539 ISVFASSRSYTLELNKNSIRDLRNLTFIDMPWMMPNNp-wQDLANDTQALWpQTQDSLLRLFALGYDAYNLVPKLRHLKL 617
WP_014950519 548 VPVYATSRSMDYDSGKNQWRDLQNVHFIDMPWLMPSHs-wQPLQQEVEQAWqNQNTMQKRLFAFGFDAYQLLPQLGMLNT 626
WP_013754689 548 ISVFASSRSYTLELTKNSIRDLRNLTFIDMPWMMPNNp-wSALAKDVRALWpQSQDNLLRLFALGYDAYNLVPKLRHLKL 626
WP_007639905 528 LSVFASSRSYSLDLNSNSLRDLRNLTFTDMPWMLPDHs-wQSLASQTTQLWpQKQDTLLRLFAMGFDAYNLLPNLRRLKT 606
WP_082633313 480 VPVFASSRSFSKELGNNSLRDLRNLMFVDMPWMLPGTn--AQIKERVNQLWpDRNDSQSRLFAMGYDAYQLVPELTTLHY 557
WP_068544897 541 IDLFASSRSHNDKLDANTRRDLTGLTFTEIPWLLSSRqanPELAEQSKQLWpQRSSSLERIYAMGIDSFQLLEKLRAMQL 620
WP_115720001 472 IASFTSSRGHPDLDSPAGLRDFNGLSFSEMPYFVSKHgqaAMMRNLMTKLRpQWPAALERLFAMGYDAADLLPHMATLRV 551
WP_117317704 586 VPVYATSRSMEYDSSNNQWRDLQNVRFIDMPWLLPAHq-wQTLENETRQLWpVRSTSQSRFFAFGVDAFQMLPYLTNLSI 664
WP_127025924 505 VPVYASSRSHQKSAEFTDRRDLQGLTFTEMPWMLSTGq-qQEFRQQFEQLFpQQDETLQRLFAMGYDSYHLIFRLKQQQQ 583
WP_121814433 654 VPGYQVNGNTGTLSSNPDCVINRKLNWLQFSQGQIV-P-------AS 692
WP_011576417 618 LPITSVKGLSGELSISADGEVHRVLPWAKVAQDRVI-P-------IA 656
WP_014950519 627 LKYLSHEGLTGTLSLNQQGEVIRKQPQAIIRNEKVQ-M-------LS 665
WP_013754689 627 LPIASVQGLSGDLSISADGEIHRVLPWAKVAQDRVT-P-------LA 665
WP_007639905 607 LPQVVSYGLTGKINVDDKGVLHRRLLWAQVAQDRVK-L-------IE 645
WP_082633313 558 IKGRQLQGLTGQLSMDRQQRIVRRLPFGKIEQDKVI-S-------LA 596
WP_068544897 621 IPMIKHQGEIGTLQMDEQGIISRSVDWGKYRSSRVQ-P-------IV 659
WP_115720001 552 ASTEPLQGLSGNIGVDANGVIYRRLKWVSIKGDKTQ-VkdhvippLP 597
WP_117317704 665 VPQASLHGLTGMLSMNANGEIKRVLPQAIIDNERVK-P-------LD 703
WP_127025924 584 FPALRYQGLTGNLALSTGGQVQRQLTWGKYSKDGLLtPrtp------ 624
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