Conserved Protein Domain Family
Methyltransf_35

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pfam20553: Methyltransf_35 
Putative O-methyltransferase
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 312 and 330 amino acids in length. An AlphaFold model shows this family are similar to known O-methyltransferases.
Statistics
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PSSM-Id: 466702
Aligned: 47 rows
Threshold Bit Score: 244.443
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
REA63571                  1 MSFRKINYKLRPAKTVERKMITESFRK--LsaFN-HISDYQYIGFGSIYFVDFVLFHKHLGI---------KKMISIEKd 68 
WP_013663167              1 MSGGSVPYHLRTNKAIERRIFFDLLGNlaLg---rDLKNYKYISLGGPMLADHQALHHELGL---------TKLVSIERd 68  Mari...
PRJNA291880:A4C39_14185   1 MSGQYIPYHLRHNKSIDREIFLESLNL--LskRL-NIQEYTYIGFGGPMLEDFRIMHNRIAL---------SDMISLEEq 68 
jgi:Mnod_4982             1 MSGSTLPYALRQNKFVDRRIFIELLGR--IerYI-PLDDHVYISMGGASLEDHRLAHAYLGL---------TKMLSFDMd 68 
TPE62585                  1 MIGKSM-VGARSIDVFDLAIFVDLLNR--VqrVC-SVTNHAYGAMSGFALDDQRRLYRALGL---------KRLLAFSTd 67 
RMA41804                  1 MSASTIPYRLRPNKFIDREIFVDLINH--LvpQR-GASEYVYISMGGMHLVDHSIVYRRTGI---------PNLYSFDHe 68 
TDU28865                  1 MSGGFVPYHLRQNKSVERAVFIDLLSRvgRstAV-PIHKFTYVGFAGPFSEDFKLIHQHLGL---------AKMISVEAe 70 
jgi:Pmen_4035             2 SAGGSIPYHLRQNKAIERNLFIDLLAR--VgrYF-NISDFQYIGFGGPFLEDFKHLHSSLRI---------SNMISLEMd 69 
PRJNA399218:CKA81_00260   1 MTGGNIAYHLRPNKAVERALFLDLLNR--IgrTSfNISSYQYVGLGGPFMEDFKALHLATRI---------SDMTCIERd 69 
PRJNA550965:FKV23_01675   1 MSGSSLPYRLRPNKAVDRELFLSLLMR--LtpKL-GLEKYHYVGLGGPFLEDFRLLHSRIGIgrkkgsrtvGRLTCVESe 77 
REA63571                 69 ANAQSRVEFNKPFSCIDMHFDTSSNVLPKLEL---------D-RPSIIWLDYDGKLS-TDCLSDLSTTCSNLAPGSVLMA 137
WP_013663167             69 SAVLTRQDFNKPYSCIECWEGATSDYINNFNE---------D-DPVIVWLDYTDTKW-GAQINDCVALIENLKEYDIFKV 137 Mari...
PRJNA291880:A4C39_14185  69 ESTHIRQKYNLPYNCIDCKLISAHDFILDYSF---------S-KPSITWLDYASPKKiQTDLDDIHLLSTKVSSFDILKV 138
jgi:Mnod_4982            69 DWIIERQKFNTPVDYIKFMKITSGDLIGSFSAvmsgigfggN-PSAIMWLDFTSPRDlRQQLGEFHKMLVTMQPCDVVRI 147
TPE62585                 68 VSLAQRQMFNKPISDARRVHADFDDIVSNWHDlfenegiedT-DKFILWLRRDAANNpASGPRQFQELANSIGLDGILRI 146
RMA41804                 69 EKTVRRQNFNRPLETVFCEQLGSDQLASKLDQivsn--fdnA-ANVVVWLDYTDPNQrLEQLQETAAVAMRLQPGDILRV 145
TDU28865                 71 DVVHRRQKWNAPIRCISYKKCSARDYIDAFDG---------S-SPTIAWLDYAEASKvGDQIAEAEFLLQKMAPYDVLKL 140
jgi:Pmen_4035            70 GNVFSRQKFNKPSSCIALRKESSSDFLNSFDFd--------AtDNLIVWFDYATP-QiSEQLAELQQLVEKLSHGDIFKI 140
PRJNA399218:CKA81_00260  70 AIVQARQRFNCPLSCVKFVLSDSSTFLDNFRA---------E-TPTVAWLDFTSPGElKQQLDDTFKLVKNLAHGDIFKV 139
PRJNA550965:FKV23_01675  78 LEIHKRQRFNRPVASIKCVHSTLEEFLDQTTF---------T-TPAIIWFDYTTPRGiALQIQRFAETVGTMPIGSILRV 147
REA63571                138 TLNVQAESiiniakdekqee-gdddeiyvsvgkEEIFEHRLKILEEQISRYkIPAD--IEAKDLTPNG-LPKLIARILEN 213
WP_013663167            138 TFNANPDSl-----------------------kENPSGNELQTFQSKANCTqLSAN--LTANDVIGMDrFALTISEMFKR 192 Mari...
PRJNA291880:A4C39_14185 139 TFPINPSSyyqrr---------------vgeslDIFKEAFINSLKSLLGKKyLDFNlqISNADLSDRK-IKALLIRIITN 202
jgi:Mnod_4982           148 TVNSSANAlyqpqiv-----------ggrketvDVFAPKRLDRLTDRLGEY-SPGG--LSVADMNDEG-VAKIIARAFGN 212
TPE62585                147 TLEIDFDVwagplyr-----------dnarltvAEREEVARARVESELSDF-LAPS--DYSNPMDLHA-LCIAVAKAYGN 211
RMA41804                146 TVNTHIPTldengdsg----------awkaagaESPGAYRCERLRAQIGEY-LPTD----LRAIAETG-FPSAMLGSISV 209
TDU28865                141 TVNANHLSlg----------------------eANNLQRRLDRAKHRFGAF-LPTPpvIDPDDIDRKG-YPRFVLKAIET 196
jgi:Pmen_4035           141 TVNATpvslg------------------hadakAEMLSRRAETARIRLGEY-APAQ--ITPNDVNTKN-YPTLLLKALIN 198
PRJNA399218:CKA81_00260 140 TLNASVAAlredp---------------gnikqHELASLRRQAFEERVGLD-KPST--INPEDFKANK-YPTLLLQALHN 200
PRJNA550965:FKV23_01675 148 TLNADPGSlgeppsgknlsvevdgeasadrahkPTKAEWRFQRFNERLGKL-VPSG--VSADAMTFRK-YGPTILRVLKL 223
REA63571                214 EISSALDTRNlglddtEYLYFKQLYNIKYEDG-AAMLTFGGIIVSADQLdt---fDSAN-FFELPYCT-PEk----dAFH 283
WP_013663167            193 ATEDALGL--------DGLEYVPLTQFRYIDNrHQMLTITGIILPEEDDislsklLIDShLESWPYMAqSWe----kVQE 260 Mari...
PRJNA291880:A4C39_14185 203 AFRSAIERGLsg--rkDKIQYYPLSLNQYNDGsHTMLTISGFFSSEQEYie---lSKACdLSNWQFYStNWe----dVQE 273
jgi:Mnod_4982           213 AARKAYPAQ-------SEFIALPLSAVRYADG-QQMLSLTVIVLKRLEVkd---fLAKTkLANWGLYSqSWq----dIHE 277
TPE62585                212 AAAAGVAGAT------DRI-FEPMSVVRCGAD-PVEITITGMVIRPKRKka---lRNAItDGAWPFASaTWd----dLKI 276
RMA41804                210 TLSKASRESG------AGLNFQPVLLTSYKDG-QRMTTATVIVDSEDHPfra-------dsKTWRFMPkDWm----dVLE 271
TDU28865                197 ACKRAMAGK-------KGHVFQPLAAFVYSDSmHQMLTATGIVLPVDKTsa---fLKETgLNKWPLATtDWgngvtdPIE 266
jgi:Pmen_4035           199 AAKHGLAGD-------SSLVLEPLASFAYTDG-QQMLTLCCVLLNTEERdq---fFDRTrLRSWPFYNdCTq----aPKS 263
PRJNA399218:CKA81_00260 201 AAKRAVNN--------TSLDVQPLTAFSYSDG-TIMLTATGIILDPNEActd-efPVSSrLSHWPFAMlDWk----yPID 266
PRJNA550965:FKV23_01675 224 AVEKQALSF-------ADRRIEWALATHYADG-QPMVTAALVVCSREDS------AAEKlIKDWEFYAtPd-----dPHR 284
REA63571                284 IKIPNLTTKEVVLLDSQIHEAYD-----------FKDLSLKAIPkplkfinSSEIKSYAEIYRFYPTFTESIW 345
WP_013663167            261 INVPDITQKERAEINRYLPCQGQdfdldvlpfklDRNARKA----------KAKIENYIKYYRFIPNFQRVIG 323 Marinomonas...
PRJNA291880:A4C39_14185 274 IAIPTLTIKEKINLDSKLPDKEA-----------------YQAAaeefslnENERDNYYKYYRLYPNFQRIMV 329
jgi:Mnod_4982           278 IAIPYLSLRERMLFNEHIPNAAPhdvftklgflfDDDEGKS----------NEIFEQYRKYYRYYPQFHHIQT 340
TPE62585                277 LLVPDLTVRERIELEKIGNNRALavtsl--gfdlDEIIGQ-----------VGVFDSFIQFHRYLPTMIAAEM 336
RMA41804                272 ISAPDLSLREKYRIDHEISKSSAdinqs-lgfplSETENKS----------IAAIESYKMLRRYYPSFHHTEA 333
TDU28865                267 IGIPEMSVRERLFIDQLMPKTKSrsvlrrmgfglAEGTEDRS---------IEALESYRRFYRHYPYFSKVIV 330
jgi:Pmen_4035           264 ISVPVLSLKERVHVESMLPGATAdeifedlnyyvGKDDQSA----------RDEMSNFISFYRMYPWYSRVVI 326
PRJNA399218:CKA81_00260 267 IDLPVLSLRERMELEKIQPNGSV-----------QDAKNTLGQVinpagipPQAVTSFAKFYRIYPEFVRANL 328
PRJNA550965:FKV23_01675 285 IELPALSSLERLTMESNsnvlrk------lgfdlAEVVDSRLG--------VDPVAVFKKFYRLYPHFSRVEL 343
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