Conserved Protein Domain Family
CE4_Ecf1_like_5s
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cd10969: CE4_Ecf1_like_5s 
Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins
This family contains a hypothetical protein Ecf1 from Escherichia coli and its prokaryotic homologs. Although their biochemical properties remain to be determined, members in this family contain a conserved domain with a 5-stranded beta/alpha barrel, which is similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, belonging to the larger carbohydrate esterase 4 (CE4) superfamily.
Links
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Statistics
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PSSM-Id: 213026
Aligned: 33 rows
Threshold Bit Score: 152.441
Created: 16-Aug-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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putative activeputative metal
Feature 1:putative active site [active site]
Evidence:
  • Comment:based on similarity to other CE4 superfamily members
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                   ##                                   
O85100        26 PETFCEQMKWLADNNWRTVTSAELEYFyqgg-tlpRKSVMLTFDDGYlDNWLRAWPVLKEYNlHAHIFLITGLIgkgnvr 104 Escherichia coli
NP_603438     27 PEIFEEHLKIIKKYNMETIKISEYYNKni-----nKNSILLTFDDGYyDNFKYVFPLLKKYNmKATIFLNTLYImdkren 101 Fusobacterium n...
ZP_06010622   26 KDEFEKHMSYVKDKKSFKMEEVEKLNFrl-----pKNSMLVTFDDGYkNTYTVAYPILKKYNiKATIFLNTKYInn---- 96  Leptotrichia go...
YP_003158702  30 WQLFDAQLRALRRFGYRSVFLREYMDIalagrlgqERVVSLTFDDGYlDNWVYAAPLLKKHGfCATIFASTDFVdpasep 109 Desulfomicrobiu...
YP_003309878  38 PEEFEEQMMLLQKYKTFKLEELDRMGNkf-----pENTVLVTFDDGYaDNYTNAFPLLKKYNiKATIFLNTAYInn---- 108 Sebaldella term...
YP_677230     38 PKELESYFSYLSENKYQTITLREIDALykakqklpEKSIVLTFDDGYyDNYSVVFPLLKKYNlKAIFFVNTLFVgeaydr 117 Cytophaga hutch...
ZP_06999229   26 TQQFKYLCKYLKRHKYRTHYLDYWYINegk--gidKKDLFLTFDDGYlDNLLVAYPIMKKYGiKGTIFINPEFVdpssgi 103 Bacteroides sp....
ZP_01624127   53 SATLQSQLEFLKTNGYRTLNLETFMAFikgevtlkEPSVLLTFDDGEkSWYDVAYPLLKRYGfNAVGFVVPHYIqekpss 132 Lyngbya sp. PCC...
YP_001169584  87 PDVFRRHMQALRDMGRIVVSSSCLRERrdsgapfdPRWVVLHFDDGYlDNMLHAAPILRDFGhAATIFVSADFIdsssgl 166 Rhodobacter sph...
YP_166776     98 PASLDRQLRLFRRMGLQVVDSETLVRArlagrpvpGNWLALHFDDGYlDNWVAAAPILRRHGaCATLFVSTDFIappqpl 177 Silicibacter po...

Feature 1                                                         #   #                          
O85100       105 srqeqeysh-----rdcerliadnrsdeVMLRWSEVREMRDsgLVEFHVHTHSHKrwdrlsv------------------ 161 Escherichia coli
NP_603438    102 epeikdnntvn-leamkkyiengkatinQYMSWEEIKEMYNsgLIDFQAHSHKHMamfkdikiegltkkdkmeapelyly 180 Fusobacterium n...
ZP_06010622   97 --------------------------ddAYLTWDEIREMYNsgLVDFQMHTHSHCpvirklqvkgffdenvnefvrresl 150 Leptotrichia go...
YP_003158702 110 rpqfdp-----------lrpdsarlpgaGFLSWSEMRALEQsgVMEIQSHGITHTwypcgpgivdfrhpgdthywmdwna 178 Desulfomicrobiu...
YP_003309878 109 --------------------------dpFYMNWDQIREMYKsgLVDFQLHTHSHFtvvkrvevqgffevgdknkrelnre 162 Sebaldella term...
YP_677230    118 sattyeladqvnsnlianyfnslptqstQYFSWEEMREMERsgLVDIQCHSHRHGmvfsntrfkqvvnvhhvsagdyfvl 197 Cytophaga hutch...
ZP_06999229  104 rtl-----------------esnkgetrGFLNWDEIKFLDKteEFDIQSHSMSHNfyfksdklidihdgsdkyhwlawis 166 Bacteroides sp....
ZP_01624127  133 -----------------------vtsgkTWLSWSELLELEQsgVMEIESHSHYHArifvepklldfyhpefpdslgldvp 189 Lyngbya sp. PCC...
YP_001169584 167 -----------------------rshgiGYMNADELRAMDAdpLIEIASHGLDHGripvsdrivdhldagnwrryaphiw 223 Rhodobacter sph...
YP_166776    178 rpml---------------gqdgplrwdGYLSWDELRALEAegTFRIEAHGTDHGriatgpetvdhltpenagrlswmqw 242 Silicibacter po...

Feature 1                                                                                        
O85100           --------------------------------------------------------------------------------     Escherichia coli
NP_603438    181 gelennfpifakrgeysgkakiikk-------------------effrtfkkfyeenienkiadkneilkkcqefidkns 241 Fusobacterium n...
ZP_06010622  151 siykngligkerekeiyfkdfdfeglpifkvrsqiaikgmklkegfiekyreieknkefqnmsvnerkkylnnifskrkn 230 Leptotrichia go...
YP_003158702 179 spadkwryldfksdpgvwgepvyehaksmdgp----vyypdervgqalrefaaargrsffdrpdwrdelrakaeelmktc 254 Desulfomicrobiu...
YP_003309878 163 mkniyrtnevregypvfkkrgetairg--------------ykvtdefmnkydellgkyrdmdrekkekilkeeiernlk 228 Sebaldella term...
YP_677230    198 ngsvqsgfplfkmrgeltqaglqide-----------------agkalfkeyysglekqalskkekkqkaqqffteefiq 260 Cytophaga hutch...
ZP_06999229  167 rpkrkpfwqlesqgnftpkgypvfeyyr------------alglrryfpdeeliklseelynentpkeqiieqlnffkkt 234 Bacteroides sp....
ZP_01624127  190 wignngsytnklqlgtpiynyaprleghsrf------idnpevretcitwvntqggttfferstwkkeltdyyhtvqkts 263 Lyngbya sp. PCC...
YP_001169584 224 slspgpkarwfea-------------------------------------------adpaplrlgapihqsdsklcgrww 260 Rhodobacter sph...
YP_166776    243 armpgdkhdwylr-------------------------------------------rsrpvplgsavpisapalaargws 279 Silicibacter po...

Feature 1                                                ###                                     
O85100       162 ------sraeqcrLMKEDILVGKQCLTEKL-GFCSSHLCWPEGYYnrDYINLAGKLGFs---YLYTTERRMNcpe--ngs 229 Escherichia coli
NP_603438    242 eyffdeseaeykkRIEEDYLENKKLIEKNI-GNQVKFFCWPWGHRskETIKILKELGVv---GFISTKKGNNsmk--pnw 315 Fusobacterium n...
ZP_06010622  231 effeeytqeefdkRVEFEIKENKKQIEENL-DKKVSFLAYPWGHRytGDIKKLEDLGVk--nFVLTTETVNNrnm---nn 304 Leptotrichia go...
YP_003158702 255 trtglethdefmlRVRRELADSKTVLEENL-GKKIDFFCWPGGGYteEVFDAAAEYYVg--tTVGSRERLRPaaldakgc 331 Desulfomicrobiu...
YP_003309878 229 hfiveyteeeynlRVENEIIKNQNFIKKNL-GKDSDYFANPWGHKskELLLILKKLGIk---GMITTKKGTNylk--pni 302 Sebaldella term...
YP_677230    261 qhvhaysdaefkaRVEKEIAENSTQINTHLsHKKALGFAWPYGHQstVSLPWIKALGIt---YFFTCKKGTNari--lnp 335 Cytophaga hutch...
ZP_06999229  235 hpgrfesdsemeeRFKYELFDSKRILEEKL-NKQITILCWPGGGYndASLRIAQEAGYwastIASADNTGFFdn-----s 308 Bacteroides sp....
ZP_01624127  264 ssgeyesesqkreQMLSDLIQSKTVLSERL-NKPIQHLCYPWGMGsnEAITLSQEAGYit-nFWVTLDERNSnkpg-dsp 340 Lyngbya sp. PCC...
YP_001169584 261 rdgareneaerdrRVQAELREARARLEAVL-GREVRFLCWPFDSWtpAARSAAEAAGF----RSFTGGRGENlpd--edp 333 Rhodobacter sph...
YP_166776    280 patgqesdaaydaRVRAVLATSRTLITREM-GRAPVLFCWPQNQTsdRARVLAQQAGF----LATTAGQARNtat--dpa 352 Silicibacter po...

Feature 1                                                                      
O85100       230 LRIGRISTKEre-------------------------------------hSGWLKRRLFYYT 254 Escherichia coli
NP_603438    316 DMIRRIELRKy--------------------------------------tPKKFKINLLVAR 339 Fusobacterium nucleatum subsp. nu...
ZP_06010622  305 KKICRINGDDfkeydkfl-------------------------kemklseNYYLALLVSKFR 341 Leptotrichia goodfellowii F0264
YP_003158702 332 FRFSRVGPPGvegrmgfry----------------------lgpwllplfLEEVRGGSRLAR 371 Desulfomicrobium baculatum DSM 4028
YP_003309878 303 YKIRRYETKS----------------------------------------MKQFKKLLFINN 324 Sebaldella termitidis ATCC 33386
YP_677230    336 DFIYRIELRKv--------------------------------------tAKRLITLTKINS 359 Cytophaga hutchinsonii ATCC 33406
ZP_06999229  309 GNIYKRIVRYpmssn-------------------------------vkcgQWVGKTRVVIAT 339 Bacteroides sp. D22
ZP_01624127  341 FYIPRLKDDYllrl---------------------------------pgvGRYPLWKIFQAK 369 Lyngbya sp. PCC 8106
YP_001169584 334 AVLSRVHVHDhaf----------------------------------gggPLWLEDLGFRAK 361 Rhodobacter sphaeroides ATCC 17025
YP_166776    353 ATLSRLHIGEdyaglrcgwiddlavraqircfqgfvgwvavlgavgalrrIVRVLVRLRSHG 414 Silicibacter pomeroyi DSS-3

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