Conserved Protein Domain Family
GT29_ST3GAL6
?
cd23984: GT29_ST3GAL6 
beta-galactoside alpha-2,3-sialyltransferase 6
ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL6 utilizes the Galbeta1,4GlcNAc on glycoproteins and glycolipids as an acceptor. Members of this family belong to glycosyltransferase family 29 (GT29).
Links
?
Statistics
?
PSSM-Id: 467712
Aligned: 7 rows
Threshold Bit Score: 389.106
Created: 28-Nov-2018
Updated: 27-Apr-2023
Structure
?
Aligned Rows:
Download Cn3D
 
putative active
Feature 1:putative active site [active site]
Evidence:
  • Comment:based on homology to other members of the family
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                ###                    ##                    #                          
Q9Y274       114 PCKKCVVVGNGGVlknktLGEKIDSYDVIIRMNnGPVLGheeEVGrRTTFRLFYPEsvfsdpihndpnTTVILTAFKPHD 193 Homo sapiens
AAH84840     109 SCKKCVVVGNGGVlrnssLGKKIDSYDIIIRMNdGPVLGyedDVGqKTTFRLCYPEsifshslhydpnTTVVLLMFKPHD 188 African clawed ...
NP_001296323 112 FSKKCIVVGNGGVlrnktLGEKIDSYDIIIRLNnGPVIGhekDVGkRTTFRLCYPEsifsnsshydpdTIVVLLIFKQED 191 coelacanth
XP_007893946 113 PCLKCIVVGNGAVlqnksLGKQIDSYDVVIRLNsGPVIGyenDVGnKTTFRLCYPEsiisdpsqydanTILVFVPFKPLD 192 Callorhinchus m...
NP_989810    137 ACRRCVVVGNGGVlrnktLGGKIDSYDVIIRMNnGPVIGyeeDVGrRTTFRLSYPEsifsdpihydpnTTVVIIVFKPRD 216 chicken
RXM99529      36 KCRKCVVVGNGGVlrnkmLGKRIDSFEVVIRINsGPVRGyesDVGkRTTFRLCYPEsifkdprdadpdTTVVIIPFKPHD 115 sterlet
XP_028655762 104 SCNTCVVVGNGAIlrnksLGSVIDSFDVIIRMNnAPVSGyenDVGtKTTFRMAYPEslfispedvdpkSTLIFMSFKPSD 183 reedfish

Feature 1                                                                        ###             
Q9Y274       194 LRWLLELLmgdkintNGFWKKPALNLIyKPYQIRILDPFIIRTAAYELLHFPKvfpknqkpkhPTTGIIAITLAFYiCHE 273 Homo sapiens
AAH84840     189 VKWLSELLmhkrvstYGFWRKPAMNLIyKPHQLRVLNPFILRQVSQNLLNFPIsfpktekpkhPTTGIIAITLAFHiCNE 268 African clawed ...
NP_001296323 192 LQWLLDLIngkkvnaKGHWKAPADTLIyKLSQIRILNPIFLKIAAFEFLHLPLvhdkkkmpvhPTTGIIATALALHlCDE 271 coelacanth
XP_007893946 193 LRWLVDVIvknkvsdRGFWKKPPASIIyRNNQIRILNPSIVKRAAFDLLKLPMdipiekppqyPTTGIIAISMALTmCNE 272 Callorhinchus m...
NP_989810    217 LKWLWEILggqkisaKGFWKKPALNMIyKSNQIRILDPSITRKTAYDWLHFPTrfpkkekpkhPTTGLIAITLAFHiCHE 296 chicken
RXM99529     116 LRWVTDVLlhkpvnvTGFWKKPATKLIyKPDQLRVLSPFYLYKAAHNVFHLPEkfll--ekilPTSGIIAITMALDvCEK 193 sterlet
XP_028655762 184 LHWMLQTLqnknvsnFGFWTIPPRKLQySKEQVRLLNPRFIRIAAYEFLNFSKrplkekipqhPTTGMIAITMALHmCNN 263 reedfish

Feature 1            ##         ###               #            
Q9Y274       274 VHLAGFKYnfsdlkSPLHYYGNAtmslmnknayHNVTAEQLFLKDI 319 Homo sapiens
AAH84840     269 VHIAGFKYnltslnSTLHYYGNEtmsvmaqneyHNISAEQMFIRDL 314 African clawed frog
NP_001296323 272 THIVGFKYnfnepnSSLHYYEDVsmsamtkipyHNITAEQAFLKEL 317 coelacanth
XP_007893946 273 VHVAGFKYdfinmnSTLHYYSNDtmssmgkmlyHNISAEQILLKQL 318 Callorhinchus milii
NP_989810    297 VHLAGFKYdftdrnSSLHYYGNEtmsqmmqneyHDISAEQKFLKKL 342 chicken
RXM99529     194 VYIAGFKYdls-sdNYLHYYGNEtmfemtkneyHNITAEQTFLSYL 238 sterlet
XP_028655762 264 VSIAGFRYrfdnvtDHVHYYGNEtmnvikmspyHNVSVERKFIDHL 309 reedfish

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap