Conserved Protein Domain Family
DUF1189

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pfam06691: DUF1189 
Protein of unknown function (DUF1189)
This family consists of several hypothetical bacterial proteins of around 260 residues in length. The function of this family is unknown.
Statistics
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PSSM-Id: 429073
Aligned: 39 rows
Threshold Bit Score: 101.935
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CDE56270      17 FKKVWYSITKFEKYPEMATEGLGRALKYLAMMCAFITVFMTISSFIEMKKVVFNLSEYIEQNIPEFSYEDG-HIQMDTEe 95 
CCO11503       9 tKLFIASLSKPEQLTAAATLKKGKVFLYFLFIAFISAIPAFLQSYQ-LLTDFNRDGQTIISEMPEFSIKNG-EFITDEPi 86 
Q3XXZ0         4 KQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPISFQVFQ-VLNNIQLDGQKIATRIPDFTIQNG-QLQTEEKe 81  Enterococcus fa...
WP_014124977   4 LQLVKNSILHFNELKNAKNIGFGKMILYLLLLSLIAAIPITLQVRQ-VFSDIQSDGQEIAEQIPDFTVEDG-KMQTNEQd 81  Tetragenococcus...
Q838I5         4 LQLFKQAFFSVSELRHAKKMAFWKVILYAVFLSAILALPITKQVFS-VLQEVQQDGQKIAEKLPDFSIENG-TLQTKAKe 81  Enterococcus fa...
WP_022743399   8 FKKFITSIYDIKVFSKYAKEGLLRAIIYGVLLSLILGGIKGIASGYRFNSDITQISEQLQSEKYKFFIENG-NLNINEAp 86  Clostridium sac...
CCZ00261      11 FKRFIMCIKDLDKYYKLIEEKFSRAILYFITLEIIFAVIISTIITYKANSIIEQVSKYAKDKLPDFEIENElKIDGDEKy 90 
CCZ17708      14 FKAFIKSIKDFDKYEDFALESIGKTTVYLLKLIAIFTVVISSLTTYRFSKALNKITAYYDDNISQLSYEDG-VLEINNNq 92 
CDD15524      18 WKRIIISIKNIEQYQILAGESTKSAIKYLLKLMVVFTLVVASAITIKFNNAVNNFKTFIEQDVAELIFKDN-VLNVKSKk 96 
CDE25707       6 FKKLWYSITNIEKYGEMAAEGMPRAISYLLKLTLIIAIVFGLGTVYRSDKGIKNTIKTVTDQIENFNYKDG-NLDTENQe 84 
CDE56270      96 pii-idniQYDGINr-IIINPLLE---SDEEKekfeAENDAT-------GVTIyfFKNQIVMrtkvdNIDTKISPYTYKD 163
CCO11503      87 ds---fskKTHSIN--FVFDPEGT---KPELEe--dLSENLV-------GIGF--LKDGLHF-----NNASQPISLTYQQ 142
Q3XXZ0        82 gf----iyQTNSII--FTFDPEGK---RTEQDistdLMGNFV-------SVGM--LKNKLIIal--pNTGTTSALLNNNQ 141 Enterococcus fa...
WP_014124977  82 gf----iyQTDSII--FTFDPKGQ---RTSDDiskdMIGNFL-------SVGL--LQEEAVLsl--qSNEATEAILGDNQ 141 Tetragenococcus...
Q838I5        82 sg---fiyQTDSII--FTFDPDGK---RTAADvqkdLIGNAF-------GLAF--LQDEFVVal--pNSGATESILGTDQ 142 Enterococcus fa...
WP_022743399  87 i-----kfEQDNTI--IYIDNSKN---MADESdlksIVINEDv------SILV--LRDGIIV-----NNYINKYKMSYIN 143 Clostridium sac...
CCZ00261      91 vletngtsNETKIK--CIFDSTSEskdSYEDE----IRTYD--------GTIIlcLKDSIYA-----QYGSMQYEQKYSE 151
CCZ17708      93 kve----atvDDIYqnVIIDTSE----LKNEQ----IEKYKEelqnkngGFLL--LRDKFLYk---nEMVQGITERNYKD 155
CDD15524      97 edetlivyKVEDMDikIMFDTSE----ISQEK----IDEYTNdiklefnGIIF--LKDRIIIk---nQMTNIPSTYNYSD 163
CDE25707      85 ei-----iiDNTQFgkIIINTKT----KENEK----INSYINsln-nqaGIIM--LNDKMIIk---sSLTSPVE-YKYQD 144
CDE56270     164 FVQnyagndvkSFSKTQLIEYMrsskmnNFYGKYMISSFISLLLVEIMITLIDALEIAAFGWLTTMITRIRIRFVAIYNM 243
CCO11503     143 MD---------GLSKEFFVNILas--mqRMTGFILVIAFLLMLLLSLFLTLLFNFLYTVFANLVTALTRRRLPFSHVFKM 211
Q3XXZ0       142 LELpytneslkNLTGKQLRSFLse---aSIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT 218 Enterococcus fa...
WP_014124977 142 FELsyddsrmqNLTGEMIQNELsq---sKLPWWTLLVALLVATYPSFINLIVILLITTIIGNLYSRIQRTSNRFLDNLKI 218 Tetragenococcus...
Q838I5       143 FIFpyskgtldGVNAQSIKTALse---aAIPWWTKLIVFLVAIYPVLIGLVLDLLIAAIGASLYSKLRFYSLRLIDCLKI 219 Enterococcus fa...
WP_022743399 144 -----------LFGDKIIDSTIlktavkNLDIMFVIASSMISIGFTIFNTLLNCLIVVAFASILTIFMRMVVKYNALYSL 212 Clostridium sac...
CCZ00261     152 IRGqlg---ldKIDKDTISEYItnn-kkQILLNIFGMLAIAMLIVVLTGDILVIISLTIMVILICKIFKLNLSYGQCVNI 227
CCZ17708     156 LLEqnn---iqTLDKQSITNMIven-qtKIYIVTFVTTFILTFSAFFISVLLDALALGILGFIIARGVKMKLRYGAAFSV 231
CDD15524     164 ITSqyn---inIIQKQDIINALsnqnlfAICSIFFITMFIYLYIIYLSSVLIDALVLALLGYITSAILKVRLKVSALYNI 240
CDE25707     145 LLKslk---itEFDKQSFIDTInsnkmiVFYISLFLALLLYSFITYLLSILWNVVILSIFGVMATWFAKIKMRYAAIFNM 221
CDE56270     244 AVYALTLPMILNMLYIIVNyfttFTISYFQVAYITI-AYIYL 284
CCO11503     212 TLFASTLPTIIFTLFNLFG----LRIAYQTELSLIV-TVYLY 248
Q3XXZ0       219 LIYSISLPTIIATILMVFL-------PSFDTSAFIAfAGIFI 253 Enterococcus faecium DO
WP_014124977 219 MIASATLPVIIGAVINSFS-------AGFDSTMLIAiLAFFI 253 Tetragenococcus halophilus
Q838I5       220 ITYCATVPVILSAILNFVN-------PMFNDGILVIlLSLFF 254 Enterococcus faecalis
WP_022743399 213 TLYAATLPLIIQTILQIVNptvnFDV------TFVLgTLTYV 248 Clostridium saccharobutylicum
CCZ00261     228 VISTFTLPHFLRTLYTIALlltgFTMEYFQVMYMII-EYIYi 268
CCZ17708     232 AVHSLTLPIVLNIIYAIIReftgCTVKYFQTMYTAI-ACIYV 272
CDD15524     241 AVYALTLPIILNLMYIIINmftgFTVKYFQIMYTAI-SYIYV 281
CDE25707     222 SVYAISLSVLLNIAYMILNifvdFEIKYFQVMYIAV-AAIYL 262
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