Conserved Protein Domain Family
acc_sec_asp1

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TIGR03713: acc_sec_asp1 
accessory Sec system protein Asp1
This protein is designated Asp1 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Statistics
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PSSM-Id: 274740
Aligned: 7 rows
Threshold Bit Score: 594.758
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_000499155   1 MFYFIPSWYNSDQKWHNEAPIWYRVLENMTFDDTVSQVRMFQNADEEVRLLLFSYNPQLRYMLHEESMLAVSYWSFFDDI 80  Streptococcus a...
WP_002470356   1 MKRFIPAWYSRNRWWESTSRPFYLKKQYTDFDDMISLMTMHSSNNVDYQLIVLSFSPYLRTFLHRYDLYESHYWSVFDEI 80  Staphylococcus ...
WP_011274656   1 MKQFIPAWYDSNNWWDSAVVPFYIKRKTTEFDDMVSLMLMHHKNNEPFNTIILNYNPLLRLFLHRHELYEMNYWSLFDEI 80  Staphylococcus ...
WP_000468347   1 MFHFIPSWYNENRTWYDNNYLWYFKPTNVGFDDTINQMKMFDYAGKESRLVVLNYMPNLRYYLHRYDLLESGYYSVFDDI 80  Streptococcus a...
WP_000873197   1 MKYFIPAWYDDQRWWQDTTVPYYQLQNKTEFDDMISLMGMHLENDLDYQLIVLNHAPNLRTFLHRYDLYETKYSSVFDEI 80  Staphylococcus ...
WP_000291147   1 MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQDIDSRLLVLAYQPHLRYFLYRHGVLEMDTYSVFDVM 80  Streptococcus p...
WP_011161544   1 MKYFIPAWHKQ----YDD---WSINIPSIENYDAAEYMTVLKKFDEEIGLIITDYQSQLLSKLNQIAFFPNTLFSVYDFL 73  Lactobacillus j...
WP_000499155  81 QNIQQKEIKLINFKELNWPKGTYFVYTPFLVLAKHGGEIIARIQFAENGNLLLIELLI-DGVLDKIMIFDDRGFVSSIKY 159 Streptococcus a...
WP_002470356  81 QGIGHQTPQAIDYRDLSWPEGTEFIFTPFQIQAITGDNTFSKIHFSQEGYLMWVEDYK-YSTIQRRFVFDDRGFISAVRT 159 Staphylococcus ...
WP_011274656  81 QGATHGTPVAIDYRELSWPEDTEFIYTPFQVLAIKSDNQFSKMIFSQEGYLICIEDYE-HKTLSRKLIFDDRGFVSSIEI 159 Staphylococcus ...
WP_000468347  81 QEIGNVRQQMIDFRQLNWPEGVDFTYTPFIVLVKKSGDLIAKVQFGEEGNLTHIDYFA-NEQIAKKYLFDDRGFLSSILY 159 Streptococcus a...
WP_000873197  81 QGFSHHAPQAINYHHLKWPDDVEFVYTPYLLKCVTSEQTYTNIYFSQEGYSIWFEEFE-RDQLQRRYIFDDRGYLSAIRY 159 Staphylococcus ...
WP_000291147  81 QDFHNLHTQVLSIRDIEWDDDCEFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEpNGQIHMHHIVDDRGFVSSIIF 160 Streptococcus p...
WP_011161544  74 QGVHGFENKVLELEDFNWPKNAIFDYGPFRTLIVLENKLYATVFYDIDGHILRISYPEnDEHKAFTLGIDSRGFISN--- 150 Lactobacillus j...
WP_000499155 160 FKQNRL-I-YQDYLNQNGVWQIREYAsK--FPRIVVNPMSDKVFNFTEYDDWDTLIRERILVLKKLEVTPDDYIIVAVND 235 Streptococcus a...
WP_002470356 160 YTPDGDnN-KKHYFSKDGEEIFVEDL-N--VNTVTINKNFQSKFKKVTYSSMAELIEEKFQSYVERELNEDDSVIVASDE 235 Staphylococcus ...
WP_011274656 160 YHDGQS-PmKRYYLAVKGQIIMTQDF-M--TEKITIQPEFYDLFQKKSYGNMDELIFEKIQQYNTSTLADDDKVIIAADK 235 Staphylococcus ...
WP_000468347 160 YDNGGE-A-YQDYLAPSGERIMREYL-RegDHHVEINPKKAIHFLKLSYSDIEELIREKYLTYLHKEVSKSDTIIVSFNQ 236 Streptococcus a...
WP_000873197 160 FDDQGE-AsYQEYLTINGDCVLHEDL-K--NGRVTVSKRYQHHYQQTEYNNMAQLIEEKFQAMIAQQIHEDDHVIVASDA 235 Staphylococcus ...
WP_000291147 161 FEDGQA-A-YQEYLNLKGEWQFRERL-Ke-GGQVEVNPILGYRFKMLTYQNMGDLVAEFFENYLQTYVKDQDIFMLPSHS 236 Streptococcus p...
WP_011161544 151 --QDDE-E-KTIYFDPYGNWRFKKDK-T--TDKITVNPEMHFC-KRREYENITDLVDEILSRYLKVNAKNNDEIIVTVDD 222 Lactobacillus j...
WP_000499155 236 IHNNLVRKSFPDQKK-IFSFFGERYSFDNrLDFNELLDEGELFIAESEKIERLLITSLQEknyssN--YVENHISRIPPF 312 Streptococcus a...
WP_002470356 236 RHNSMMARTIDAPSL-CFSIFTERNKVVT-QDLYDSISRAYYCLVDTQANQNMIEHYAGL-----N--MNNFNLLRVTPF 306 Staphylococcus ...
WP_011274656 236 RHNYVLTDTFKPENM-CFSLFSQRNAYID-ATLLETIGKANQCIVDTQANATKLNQFITQ-----NpeYQPFKIMRVTPF 308 Staphylococcus ...
WP_000468347 237 VHNAFIVGNTSKGNL-ILSVFSERNNAHNvLEDYSSLSRADAIICDRLDIAAQLKEKIDK-----P-------VVHVSPF 303 Streptococcus a...
WP_000873197 236 RHNRQIANHIPAKSL-SYSFFKNRNETVS-DEEYQSIVKNAHLIVDSVQLERDLISHQEK-----Y--QRENTMIRITPF 306 Staphylococcus ...
WP_000291147 237 HHDQLVLDRLPSTNPkLLSLFIGRNPQDTfRDLDVTFEKSDLILVDREDSLRLLQELYPE-----R----MHQCYHLSSF 307 Streptococcus p...
WP_011161544 223 ESSFNNEIIEPYKPL-YII-----NRHHPySKKIGSLARAKVIVSSNE-IKQNLEKNYRE-----Q-----FDISVIPVF 285 Lactobacillus j...
WP_000499155 313 DTRLRLGQSQNIEELIAYLLVDDLSQTYLSEVLDQLLAKMEVNPS-LELKIVSYKNDYdMTSLKEQVKDKILSSKnpDYF 391 Streptococcus a...
WP_002470356 307 DAQSLPNQSSQLYDTYIGLWIDGLDEIEIREIVNSLFQYIQHKDG-YKLKILTKSRDN-LTENLIDEVAHLNDLYhqEKK 384 Staphylococcus ...
WP_011274656 309 DAQMLPNISSQLYETNIGVWIDSLSEEDLKTVIDQLSQYVSQHEQ-TIIHLLTRLNENdIQQWLRDEIDQLNALLnvEEE 387 Staphylococcus ...
WP_000468347 304 DTRLALGKSNQVRDLEIYFVVDRLSHKELQKSLTSLYKVMLKNND-IKVTFVSYEREFeSRQLTYDYLKEATKVF--DQK 380 Streptococcus a...
WP_000873197 307 ETRQSPNISSQLMETFIGVWIDGMSDADLQQMMQRLVDYIAQEDY-YRLILLSRHQ-NdIPMWLRECITSVNEEYqaKQN 384 Staphylococcus ...
WP_000291147 308 DTRLRLGRSQTKKESIIYFQLD-FEQGIDNQALLQVLSFVAENKD-TEVIFGAFAASQeQMNEVEGIVESFIQENiqSEN 385 Streptococcus p...
WP_011161544 286 NSEFRLGHSQRQNVQEIGFFAENANDENIHQIIQKLCNYILKNPDnYSLKIFTYNFWK--ADHVNKILEQIKEE---NKN 360 Lactobacillus j...
WP_000499155 392 F-T--SlsleDENHF----KEEQKtkirgISFDIYTNENQIIDALDTARLVIDLRDDPDLYTQIAALSSGIPQINKVHTN 464 Streptococcus a...
WP_002470356 385 E-I--S----DVIEDviqnKKETI-----IDIETVPFEEDLVSVISKLRVVVDLSLEPKLFLQICCIGAGIPQINKKRTD 452 Staphylococcus ...
WP_011274656 388 E-F--S----PEVQDilqtELEEDei-ekVKLIYVPFEEDLMKELSQLRVIVDLNQEPDLYLQISSISAGVPQINRRETD 459 Staphylococcus ...
WP_000468347 381 F-F--SlsddDANQVlmqsDEVEKek-trLSFTHPLSETDIINRLEYVRLIIDISKIPDLYTQIAGISSGIPQINTILTE 456 Streptococcus a...
WP_000873197 385 a---------DVNVSalmtPEDQDd---iIAVKTIHAEHDVVEALRTLRLVIDMSKEPDLYLQISAISAGIPQINGQQTD 452 Staphylococcus ...
WP_000291147 386 LgK--AidygDAENPl---EENQHqd-lrLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGIPQINLVETV 459 Streptococcus p...
WP_011161544 361 S-FilGkseqAENAPidglDDEVSlpeldVAHTRLTNISDVLSNLDKMRLLINWGKADEL-MQISGVSIGIPQVQNFSSV 438 Lactobacillus j...
WP_000499155 465 YVEHQKNGWIISDSTELNNAIDYYFDGLMNWNKSLVYSVKKMGDYTSGKILQRWRKLL 522 Streptococcus agalactiae
WP_002470356 453 YVKHMHNGYIIDDISQTVESLDYFLAHLKNWNYSYAYSMRLTDDFSSINIIHQINQLF 510 Staphylococcus epidermidis
WP_011274656 460 YVDDKLNGLIIDNIQQLRVALNYFINNLKNWNYSFAHSIKLSDEFSSEKIIQRLNSVI 517 Staphylococcus haemolyticus
WP_000468347 457 FVEHRKNGYIIEEIQELEKAIPYYCEQLTNWNRSLIYSIDKINDYTGGQLVERIINSY 514 Streptococcus agalactiae
WP_000873197 453 YVSDYDNGRIINTVDELDDALNYYLFYLKNWNYAYAYSLKLIDAYASKNIINQLDELI 510 Staphylococcus aureus
WP_000291147 460 YVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQFLGKLEKWI 517 Streptococcus pneumoniae
WP_011161544 439 TVVDNKNGRIIKKISELLPVVDEYLTNLNSWNQTVVYNVQLMNQYSEENIIEKWKEVF 496 Lactobacillus johnsonii
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