Conserved Protein Domain Family
BTB_POZ_BTBD18

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cd18293: BTB_POZ_BTBD18 
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 18 (BTBD18)
BTBD18 acts as a specific controller for transcription activation through RNA polymerase II elongation at a subset of genomic PIWI-interacting RNA (piRNA) loci. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids.
Statistics
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PSSM-Id: 349602
Aligned: 5 rows
Threshold Bit Score: 159.956
Created: 18-Sep-2017
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
B2RXH4         19 LAFLQLHHQQQSDVFCDVLLQAE-GEAVPAHCCILSACSPFFTERLERerp-----------aqGGKVVLELGGLKISTL 86   human
XP_014353188   19 TAFLQLHQQQQDGVFCDVILQAE-GESILAHRCVLSAFSQYLRGRFSSee------------phSHKVLLELHELKAKTL 85   coelacanth
KYO40731        1 MAFLQLHRQQRADVFCDVILQAE-GEAIPAHCCILSACSPFFTERLERemp-----------pkGRKVVLELRGLKIGTL 68   American alli...
XP_021175945   12 QLLEQLQRQQNSTQFCDILLQTE-GISVPAHSCVLAALSPYLSQRLSAaps----------ppaGQKRRLPLQAVTAHTL 80   mummichog
XP_017951394   17 TMFLQLQRQQNTGFFCDVTLQGGeGEGVSVHACLLAACSPYLAKLLASvtevsqldtdsaiqtdCTGHILTVPGIPSCYL 96   tropical claw...
B2RXH4         87 RKLVDFLYTSEMEVs-qEEAQDVLSAARQLRVSELESLQLEGGKLVKAPQGRR 138  human
XP_014353188   86 KKLVDFIYTSEIQIq-lDEAEEVLQAARFLQIQELENLELEGGKLAKNPPSRR 137  coelacanth
KYO40731       69 RKLVDFLYTSEMEVs-rEEAQDVLAAARQLQVSELESLKLEGGKLVKQALGRR 120  American alligator
XP_021175945   81 LKLVGLLYSGELEVkssEERRDVLAAAHRFGLADLVVGCGDGGGRGAAPPDRR 133  mummichog
XP_017951394   97 LPLVHYMYTSELEVt-pENVHGVLEAARRLQIPELEGLRLEGGRLVRPELARK 148  tropical clawed frog
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