Conserved Protein Domain Family
MIEAP

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pfam16026: MIEAP 
Mitochondria-eating protein
This domain is found at the C-terminus of mitochondria-eating proteins. This family of proteins regulate mitochondrial quality. They have a role in the degradation of damaged mitochondrial proteins and in the degradation of damaged mitochondria.
Statistics
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PSSM-Id: 464982
Aligned: 46 rows
Threshold Bit Score: 138.541
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EKC40786  34 RPTRLGEMYS-QLFDDEWSEAFEAFKDSTIAKEgdd----ddELYPNILSILQtLEAFSFCRekscEQLQDLENKIKEAL 108
EKC28786 489 RMRKISERFAvELYGGLWREAFEKLTTVFKREE---------KKSLQILMDFC-TEAYLHCR----RTARQQLDSVYSLL 554
EKC40300 537 RPTRIAEKFS-ELYDNEWTDAFEALTSQYHMSE---------REAVDLLLRIL-KDCFNFGK----VAASGQLSELHKVL 601
EKC18696 222 RPTKLAEKFS-ELYDNAWTDAFEELDNTFHNE----------EETIKVLLRIF-QEAYTFCV----ETENNYETRIGQAV 285
EKC33264 226 RPTKIGERFG-LIFDDEWSEAFEELTGGGMDD----------QSVISNLLQII-QHGYEYCM----KKADEQLEDLQSVM 289
EKC21464 186 EVNDIGKKFS-DVYNNEWAKLFDSLKSEIEDE----------TARIEKLCGCL-LMAFKFCKeeseKQMNNLQVATTNVL 253
EKC42429 291 RPTKIGEFYS-ELYDNEWSEAFEVIKPLVYPNAtedpdteyfEEVLRILKNIL-MAAYEFSA----ERTEKHLEDIKLTL 364
EKC42425 110 SPDKIAESYK-ELYHNEWSAAYKALQKTGMIVMe--------EEIVKKLSTIL-HLVYELCR----DEAKKHRSKIMETL 175
EKC42424 648 RPTKLAEQFR-ELYDNEWTCAYEELQKESGKKDe--------EEIVKKLGKIL-KLCYEFCV----RQAREHRHKIRETL 713
EKC35236 265 VTDKLADAFA-ELFRKQWLGALKEKNNGTGHS----------EKNLIYLADIT-KKCQNYLD----EVCEKEYNNLCEVI 328
EKC40786 109 KQNTaDTPQTKTSdseekmEVDqsppeagdnkvEkpsqgALDQTVERHSKELRKAASAETVKy-qAQIfi----kERLPK 183
EKC28786 555 TNPSvTHGRNSISrrspssKQS-----------TpenipPSLRHQIVQFRKDPSRDFLDSLY---DDFlsvldfqKSRHL 620
EKC40300 602 LMLHtTGRTRETVvlssvkKLS-----------K-----EELKAIKDIRKACAVHAFFSETP-------------DGRTA 652
EKC18696 286 FTLA-SKTG----------SHQ-----------I------KNENVEIKKVLADLRISLSTAC---CSVieemvlsKLPSI 334
EKC33264 290 KIPI-LQPFQIKHslhvpkDMV-----------Q-----ILTTATLKHAKDYRKVTASISSPe-vCKVflreesdFLKRR 351
EKC21464 254 SFRS-TQNEENEEvggqnnSVA------------------LSQEACVHLQKLRKQCYSLSLPk-vRRMf-----rESCTF 308
EKC42429 365 LGTI-TDQEKDKA------KGT-----------E------YDRFVTEHAMKYRKEAAAYAIKmasKAF-------KRDGL 413
EKC42425 176 VYPL-GVSATIDEdg--hsHFQ-----------QahvdpETDRKLQPEVHRIQHETGVYAVPa-vQEIfw----hKHGGG 236
EKC42424 714 VYPTgVQATINANvepnieEIL-----------K-----PKVRQIQRETGVYAI-PAIQEIF----RM-------EHERD 765
EKC35236 329 LKPM-GQIDSRYVhi--peDLR-----------S------LVRVRCRQVQRDTMPISLPIIK-------------EVVIR 375
EKC40786 184 VLQDDKvrQDQRVISYVQKCVELCWFMNVQDPPMELVAPK-EGEDVDKNLFSHHGRKGKKVQTCVWAALLL--HKEGPVV 260
EKC28786 621 RSFHMK--EVKDIAPYITRCLAISWEMVVQDPPMYLQFKVrHGTPVDREKYNFYTTEGDVVDYLVWPAVLR--EENGAVL 696
EKC40300 653 LSDAQQs-SC---AGFITRAVELCWLMNVQDPPLVITWSVkPGEICDNTRYKQFTHTGQFVEFLVWPPLYL--FKEGHLL 726
EKC18696 335 LKSIDVa-ACPLTKLYARQCASLSWKMRIRDPPLFVRFEFrCGTTFNADVLKRYTKTGGYLDFLVWPALYL--HEKGPVL 411
EKC33264 352 LQTLSSg---EKLRVYIQVCIEQLWLMCVQDPQMSLEFAD-PNTPIQKDLYKFHEKKGTIVHLTVWPVVFL--HKGGPLI 425
EKC21464 309 LTTTNEa-ILRDFEAYLTRCVDTCWYMCIQDPPLNIKIPE-KGDTVDTKQFNLYKSEGDIVDVCVWPALLLggDDSTDIV 386
EKC42429 414 QKFLKQksEDPKLLAYVDKCVELTWYMRIQDPPMHL-HCLqEKETISKAEFAFHGRKGKTTLVCVWPALLL--FEGGHLV 490
EKC42425 237 FMETGWd-KSKEIMAYVESCVRLCWLFSIQDPPMKLSWPE-EGSEINEHVKVYTK-HGKRVHYTVWPALYL--HENGALL 311
EKC42424 766 IKRNEWd-ESKGISNYITKCVQICWLFAIQNPPMKLNWPK-EETMLDDHLVEFTK-RGTHIKFVVWPTLYL--HDKGPLM 840
EKC35236 376 DKIPEAh-RSPALKKFVDRCVELIWMFAIHDPPLQLEWAR-EGELMGSNLESYTS-RGNRVGFNVWPTLRQ--FRNGPVL 450
EKC40786 261 CKGYILP 267
EKC28786 697 QKGKVQA 703
EKC40300 727 SKGVVQC 733
EKC18696 412 AKGVAQP 418
EKC33264 426 SKGYVLP 432
EKC21464 387 CKGQVLT 393
EKC42429 491 TKGHVLP 497
EKC42425 312 SKGVVQP 318
EKC42424 841 AKGVVQP 847
EKC35236 451 SKGVVQP 457
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