Conserved Protein Domain Family
DD_RIIAD1
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cd22971: DD_RIIAD1 
dimerization/docking (D/D) domain found in RIIa domain-containing protein 1 (RIIAD1) and similar proteins
The family includes uncharacterized RIIa domain-containing protein 1 (RIIAD1), which contains a C-terminal domain that shows high sequence similarity to the dimerization/docking (D/D) domain of regulatory subunit of cAMP-dependent protein kinase (PKA).
Links
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Statistics
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PSSM-Id: 438540
Aligned: 86 rows
Threshold Bit Score: 42.0046
Created: 29-Apr-2021
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Conserved Features/SitesClick to see Conserved Features Help
 
putative dimerputative AKAP
Feature 1:putative dimer interface [polypeptide binding site]
Evidence:
  • Comment:based on the dimer structures of mammalian RIalpha and RIIalpha D/D domains
  • Comment:the Dimerization/Docking (D/D) domain of R subunits dimerizes to form an X-type four-helix bundle
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1             #  ##  ##  ##  ##  #### ##  # #      
A6NNX1        40 RTHKEVEWLISGFFREIFLKRPD-NILEFAADYFTDPRLPNK 80  human
GBG30745      35 RDHPELKGMLNKFFLKVLNERPD-DIESFAAKYFTDSASYEA 75  Hondaea fermentalgiana
XP_023238021  38 EDHPEIKSIIRKYLRDLLEVQPD-DITQWTSEFFCQKDLRFI 78  bark scorpion
XP_030765289  55 YDHPEIQAMLQIIMRKLLLERPShDIETFIGRYFVDSWAEIE 96  rice weevil
XP_017783266  81 KSHPEVRAFSSLILQYVLKKKPRkDIHNTVYEFFNRPQCDVR 122 Nicrophorus vespilloides
XP_031353500  55 ATHPEIRALVALATRHVLQERPRaKLHEHIAHFFSQERGVLE 96  common eastern firefly
XP_019877143  61 QEHPEVEAIIMLILRKVFQRQKPtNIIQFVAQYFHQSFYDIE 102 small hive beetle
RKP00804      39 RQHPEVHTIIRCLTRQIMKHQPD-HIEPFLCEFVASEAFDTA 79  Caulochytrium protostelioides
XP_022914474  55 AGHPEVRACVALITRYVLQRCPRnNIHDVIAQFFSRSKVDIQ 96  Onthophagus taurus
XP_008193632  55 SEHPEIRGLIVMILRLLMKKKPKyDIYEVIGQYFTKPSVDLK 96  red flour beetle

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