Conserved Protein Domain Family
CobK

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COG2099: CobK 
Precorrin-6x reductase [Coenzyme transport and metabolism]
Precorrin-6x reductase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Statistics
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PSSM-Id: 441702
Aligned: 350 rows
Threshold Bit Score: 115.636
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015044968   4 KPVFWIIAGTTEGRELIDELRLSNAEVYVSVATDYGRELIQPdkNIHIQAGRLNREEMIALIWEVKPDCVIDTTHPYARI 83 
NP_924582      1 MSMIWLIGGTSESRSIAQALAGARVPWVATVTTARAAGLYTGlp-gEVGVGPLNTEALGAFLAAHRPLAVVDASHPFAAQ 79 
WP_012954622   4 NGKLWLIGGTGDSAKIAKIITNNFFPCIATATTSQAIDLYKEapKINLRIGRLSTKDIRNFCYQEKIKGIIDASHPFAEN 83 
WP_015170656   4 AGKIWLIGGTQESARLARQLAQAGLPCIVSVTTEAARSLYPEtpEIEVWVTRFDAPTLASFLDTQDIRGILDASHPFATE 83 
WP_015155378  54 LTPLWLIGGTQESAQLAEAIARANLPCIISVTTESARALYPDaaCLQVRVGRFTCLEIEAFVQQQGIIGVLDASHPYAVE 133
WP_015189134  18 YGKLWLIGGTQESVEIAAAIANFNIRCIISVTTSAARSLYNPapCLTVWVGRLTGAQIPEFVKQQQIIAIVDASHPYAVE 97 
WP_015228228   1 --MIWLIGGTSESVLIAETLLAQGLLCLVSVTTKSAIDLYPKtdLITVKVGALSFEKMITLAETYGIEKIVDASHPYAAA 78 
WP_015224447   2 KRKIWLIGGTSESVVIAEKLMGYGYHCLVSVTTEAAIALYPKseLMTIKVGALSREEMAQLIQENQIKIIVDASHPYAIV 81 
WP_015220184  26 GLMIWLIGGTSESVIIARLLSDLKQDFVVTVTTDSACKLYENinDIQVVVTKLSLAQMRYFISVWQVFAIIDASHPFALE 105
WP_080810056   3 CLRIWLIGGTRDSAEVARGLVEAEIPCVVTVTTPAATRLYPQapTLTVRVGKLTREQLFTFVVDESIGAVLDASHPFAVE 82 
WP_015044968  84 VTDNICEACRETA---TDYIRLQREPGRLvPndssfdaNiL-ENMIYADNSEDAVRVLN-DKTGNIFLSCGSKEIKTFTG 158
NP_924582     80 ISRLAMAV----G---LPYLRYERPSVSL-A-----------PETEQFPDFAALVHSQV-LDGRRVLLTVGVKALPLLAP 139
WP_012954622  84 ISQQAISIAQSSG---IPYINYQRSSLPI-D-----------SQITYLDSLETLIEKEY-LTNKRVLLTIGCKFLPMFKL 147
WP_015170656  84 ISQQAIAAASAQD---VPYLRYERPDLSL-En------L-S-PGVQTVPSFEALLQQGT-LVGQRVLLIVGYRPLGLFRG 150
WP_015155378 134 ISQSAIAVCQKLG---IPYLRYERPVFKG-Vgt-----gwElGAEERIDGFESLLSGDY-LQGQRVLLTVGYRPLHLFQS 203
WP_015189134  98 VSQNAIAAAQHLQ---IPYLRYERPILSS-Tv----------DGTEHFDSFEALLSTNR-LQNKCVLLTVGYRPLHLFQA 162
WP_015228228  79 VSQSAIELSQQLQ---IPYLRYERPQVSP-D-------N-S-FPIIELDSFDTLVNGDY-LHDHRVLLTVGYKALPQFQS 144
WP_015224447  82 VSENVIALANQFN---LPYLRYERPALSS-D-------N-D-PHTLILDSFDTLINGDY-LHQQRVLLTVGYKALSYFQS 147
WP_015220184 106 VSQNAIHLVTSSQglcLSYLRYERETVTT-N-------N-H-KNVFYYPDLQSLLSDNWiLKQKKVLLTIGAKYLHLFKP 175
WP_080810056  83 ISHGAIATAQQHH---LPYLRLERPPITL-Eas----dT-E-ATVTEVPDLGTLLANGS-LQGERVLLTLGYRSLGACRP 151
WP_015044968 159 IKdYQERVFARVLPMQDVMEKCEKLGFKKSNISYMQGPFSKELNIAMLKASQARFLVTKDSGETGGFQEKIEAARELGIT 238
NP_924582    140 LQ-GRAALWARVLP--ESAAQAHSAGFALNRLILTRPPVDAGAERELWQRLAVDTVVTKEGGEAGGVDVKQVVARQLGVR 216
WP_012954622 148 WH-EKSLLFTRILPRLSSLEIALAAGFKEKHIISLRPPINLELEKAIWEQWKIDIVVTKASGKQGGEDIKKKVSKILGTS 226
WP_015170656 151 LQ-AQATLFARLLPSIPALEAALAAGFSPDRLMALRPPVSEDLERSLWQHWGITHVVTKASGQAGGEDIKRRVAADLGIP 229
WP_015155378 204 WQ-DKATLFARILPSAIALESALKAGFANDRLICLRPPISAALEAALWRQWNISVVVTKASGAPGGEDVKRTVAAELGID 282
WP_015189134 163 WH-DRATLFARILPSAIALEAATKAGFTPERLICLRPPISAELELALWRQWKIQLVITKASGKPGGEDTKRLVATQLGIP 241
WP_015228228 145 WH-QKATLFARVLPSVSSVENALEAGFSPKQLIALRPPVSYELEKALCEQWQISLIVTKASGKAGGEDIKRQVATALGIP 223
WP_015224447 148 WQ-EDALLFARILPTVTSLENALAAGFTHKQLMALRPPVSYDLEKALCEQWKISLIITKASGSAGGEDTKQAVAKALDIP 226
WP_015220184 176 YH-HQAQFYARILPYQSSLELAEKAGFGCDRIIAIRPPLSLELEKALWQLWDIEIVVTKAGGKAGGEDIKYQLAEELKIP 254
WP_080810056 152 WH-QHITLFARILPSTTALTAAFAAGFTADRLIALRPPISPDLERALWQQWQITTVVSKASGQAGGEDTKRQVAAQLGIP 230
WP_015044968 239 VVLIRRPEQPETLEhpgkIDEKEdaqqctfcsqeQILQKLAR 280
NP_924582    217 LVVIARPTLAYPRQ----TANLS-----------EVLAFAQK 243
WP_012954622 227 LIIIQRPSINYPKS----TEQIS-----------DIINFCSQ 253
WP_015170656 230 LTLVQRPRLDYLAQ----TEDLQ-----------RAIAFCQA 256
WP_015155378 283 LITIARPNIEYPQQ----TSDLS-----------VALDFCRM 309
WP_015189134 242 LMTISRPTVNYPQQ----TSDLA-----------VALDFCHQ 268
WP_015228228 224 LIVIRRPELAYPQK----TSKLE-----------SVVNFCCE 250
WP_015224447 227 LIIIDRPHLAYPQK----TSKLE-----------DVVNFCLD 253
WP_015220184 255 LVVIKRPSLNYPLM----AKSVE-----------DVKEFLKN 281
WP_080810056 231 LLIVARPQVAYPRQ----TDSVA-----------EALTICQH 257
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