Conserved Protein Domain Family
F420_Rv1855c

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TIGR03560: F420_Rv1855c 
probable F420-dependent oxidoreductase, Rv1855c family
Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes one such subfamily, exemplified by Rv1855c from Mycobacterium tuberculosis. [Unknown function, Enzymes of unknown specificity]
Statistics
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PSSM-Id: 274648
Aligned: 16 rows
Threshold Bit Score: 281.127
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011605917   2 DLRIFIEPQQgaS-YERQLAVARAA-ED-AGFDGFFRSDHYLRMGPGD-PSPGPs-DSWVTLAALARETSRIRLGTLVTS 76  Frankia alni
WP_011604580   9 DFTWSGGPQT--L-AQDLTRVAVAA-ED-AGFSKLSVMDHVWQIGMIG-PPEHDmlEAYTTLGYLAARTTRIELLAWVTA 82  Frankia alni
WP_011438113   9 DFTSPHGSGR--L-GEDLAEVVRVA-DT-VGFDYLAVMDHFFQIAMVG-PAENEmlEAYTTLGFLAAHSRRAKLLTLVTG 82  Frankia sp. CcI3
WP_011563207  16 DLTEIEDPAE--Q-YEAMTRVARRAdEL-DGYDSIWVYDHFHTVPE---PTRNTtfECWTITAGLARDTRRVKVGQMVTC 88  Rubrobacter xyl...
WP_003873801   9 DF-LPGDPAR--L-GPTLTEAARAA-EQ-GGATLLTLADHFFQMEQLG-PAENPflEGYTSLGFLAAQTSTIELALLVTG 81  Mycobacterium a...
WP_011728963   2 RFAFKTSPQN--TtWQDMLAVWQTA-DDiEVFESGWTFDHFY--PIVG-DSSGPclEGWTTLTALAQATSRLRLGTLVTG 75  Mycobacterium s...
WP_003895075  11 NFSYGTGVEE--L-FPTVIAQAKEA-ED-AGFDTVFVMDHFYQLPGIG-EPEEPmlEAYTALGGLATATERVQLGTLVTG 84  Mycobacterium s...
AFE13090      11 NFSYGTGVEK--L-FPSVIAQAREA-EA-AGYDSLFVMDHFYQLPMLG-TPDQPmlEAYTALGALATATERLQLGALVTG 84  Mycobacterium t...
WP_011208745   4 gfhlpifdidggtsaiagelaragaaaeaagaTWLSFMDHYFQIEPTGlPAEANmlEGYTALGFLAAHTTTVELGLLVTG 83  Nocardia farcinica
WP_012259143   4 DVALMIEGQNglT-WSRWQRLAQAA-ED-LGFAGLYRSDHFTNAN----PPEKEslELWVSLTWLASHTKRIEFGPLVSP 76  Chloroflexus
WP_011605917  77 ATFRLPGPLAIAVAQVDAMSGGRVELGLGAGWFEAEHTAYGIPFPSVEERFDRLTEQLAIITGLWgTPPGESFshDGRYY 156 Frankia alni
WP_011604580  83 VVYREPGLLAKLVTTLDVLSEGRAWLGIGAAWNEPEARGLGLPFPPTAERFERLEEALEIILQMW-SGRDAPY--SGRHY 159 Frankia alni
WP_011438113  83 TVYRAPGALAKIVTTLDVLSGGRAWLGIGAAWYEQEAVGLGLPFPPLAERFERLEETLQICLRMW-SGDESPF--SGRYY 159 Frankia sp. CcI3
WP_011563207  89 NGYRNPALLAKMASTVDVMSHGRLLFGLGAGWYEHEWRAYGYGFPDVPVRMRMFREACEIVHRMW-TEDGAVF--EGEHY 165 Rubrobacter xyl...
WP_003873801  82 VTYRYPGVLAKTVTTLDVLSQGRSMLGLGAAWYEREHTALGIPYPALSTRFEMLEETLQICRQMW-SDDDGAY--QGKHY 158 Mycobacterium a...
WP_011728963  76 VHYRHPAVLANMAAALDIISNGRLELGIGAGWNEEESGAYGIELGSIKERLDRFEEATQVLIGLL-SQDSTDF--DGAFY 152 Mycobacterium s...
WP_003895075  85 NTYRNPTLLAKAITTLDVVSRGRAVLGLGTGWFELEHDQLGYEFGTFTQRFEKLDEALQIILPML-KGERPTF--SGKYY 161 Mycobacterium s...
AFE13090      85 NTYRSPTLLAKIITTLDVVSAGRAILGIGAGWFELEHRQLGFEFGTFSDRFNRLEEALQILEPMV-KGERPTF--FGDWY 161 Mycobacterium t...
WP_011208745  84 VTYRHPGLLAKIVTTLDVLSGGRAVLGLGAAWYEREHRGLGVDYPPLAERFERLEETLRICAQMWdPQNNGPF--EGKHY 161 Nocardia farcinica
WP_012259143  77 VSFRHPAMTARMAAAVDDLSGGRLQLGLGAGWQEREHTMFGFDLLEVAPRFQRFREGLEVVTRLLrSDTPVTW--IGEYY 154 Chloroflexus
WP_011605917 157 QLADSPALPKPVQRPRPPIIIGGAGPRRTPQLAAAYAAEFNAAFAPaeVVGQRFARVREVAAAAGRDPADLVYSTS 232 Frankia alni
WP_011604580 160 QLERTLNVPAPLRRPHPPILIGGSGEKKTLRLVARYAQACNLFAGP--DVEHKLDVLRAHCQDVGRDYDEIEKTVI 233 Frankia alni
WP_011438113 160 QLARPLNSPRPLTRPHPPILIGGGGERKTLRLVARYAQACNLFPGP--DLARKLQVLREHCEREGRNYDDILKTVV 233 Frankia sp. CcI3
WP_011563207 166 RIDRPINEPKGLQKPHPPFWIGGGGERVTLRLVARWGDACN-VFGDpdTLRHKFGVLRRHCEEVGRDYEEITRSTS 240 Rubrobacter xylanop...
WP_003873801 159 RLAETICAPQPIRR--PPILIGGDGEKKTLRLVAQYADVWNSMSNDlaELEHKIEVLHRHCDAVGRDPRDIRKTCg 232 Mycobacterium avium
WP_011728963 153 TLKNARNEPKGPQRPHPPIVMGGSGEKRTLRITAKYADHWNFVLGTpeEFAHKRDVLWSHCADIGRDPKEITLSAH 228 Mycobacterium smegm...
WP_003895075 162 RTENALANPR--FRDHIPLMIGGSGEKKTIPMAVRHFDHLNVIAGf-dELARKLDVIKKNCDEIDRDPATLETSVL 234 Mycobacterium smegm...
AFE13090     162 TTESAMAEPR--YRDRIPILIGGGGEKKTFAIAARFADHLNIVAAv-dELPRKMRALAARCDEAGRDRSTLQTSLL 234 Mycobacterium tuber...
WP_011208745 162 RLAETLCAPQPLHRPR--VLIGGGGEQKTLRLVARYGDACNLFGTSpqDVEHKLDVLRRHCEAEGRDYDRIRKTIL 235 Nocardia farcinica
WP_012259143 155 QLREAILLPRPQRPGGPPIVIGGNGEQRTLPLIARYADEWNAVFVPpaRFAELNAKLDNLLDAAGRPREAVRRTLM 230 Chloroflexus
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