Conserved Protein Domain Family
DD_TPGS1

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cd22960: DD_TPGS1 
dimerization/docking (D/D) domain found in tubulin polyglutamylase complex subunit 1 (TPGS1) and similar proteins
TPGS1 is part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1. It is required for the development of the spermatid flagellum. TPGS1 contains an N-terminal domain which shows high sequence similarity to the dimerization/docking (D/D) domain of regulatory subunit of cAMP-dependent protein kinase (PKA).
Statistics
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PSSM-Id: 438529
Aligned: 25 rows
Threshold Bit Score: 56.4457
Created: 29-Apr-2021
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6ZTW0        37 DFLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENMG 75  human
XP_005999534  30 EFLSQVGAGTMLREALLKLLQSRPEDPVGFLADHFESLV 68  coelacanth
XP_003642907  26 EFLLQADVTAMVREALLKVLEARPEEPVSFLADYFERLV 64  chicken
PWA29804      29 EFLEQAGVGDLLRGAILKMVEARSDDPIGFLADHFCNLA 67  western mosquitofish
XP_018111537  36 EFLAQTGARDMLRESVLKLLEARPEDPTAFLADYFEKLW 74  African clawed frog
XP_028672229  26 EFLTRLGTGDLLRGALIKLLEARPDDQLGFLADHFKNQL 64  reedfish
XP_002121243  20 EYMQRNGVTQQIKEAMLKLIENRPQHPMLFLAEFFDSIN 58  vase tunicate
RDD41016      14 EYLDRAGVASNLQSALLLVLENKPDDPIYFLSQFFRNAC 52  Trichoplax sp. H2
PIK57815      37 RLAESSQVNNWIKNALSQLVANRPDDPIAFLDQFFGNLG 75  Japanese sea cucumber
XP_007897087  12 GARLPPGVGDVVRDALLRVLENRPEDPLSFLSEYFGNLT 50  elephant shark
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