Conserved Protein Domain Family
aldehy_Rv0768

?
TIGR04284: aldehy_Rv0768 
aldehyde dehydrogenase, Rv0768 family
This family describes a branch of the aldehyde dehydrogenase (NAD) family (see pfam00171) that includes Rv0768 from Mycobacterium tuberculosis. All members of this family belong to species predicted to synthesize mycofactocin, suggesting that this enzyme or another upstream or downstream in the same pathway might be mycofactocin-dependent. However, the taxonomic range of this family is not nearly broad enough to make that relationship conclusive. [Unknown function, Enzymes of unknown specificity]
Statistics
?
PSSM-Id: 275104
Aligned: 14 rows
Threshold Bit Score: 783.185
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
ZP_08197974   11 AQQLVDGKLGAAASGeTYAILNPATGQEIGRAPDSTAQDVDAAIAAARRAFDETDWSTDVAFRVRCLRQLHQAILDNADA 90  Nocardioidaceae...
WP_003897260   9 SQLLIDGKLVAGRKG-VFDTVNPATEEVLGVAADATAEDMGDAIEAARRAFDDTDWSTDTELRVRCIRQLRDALREHVEE 87  Mycobacterium s...
WP_011561955   9 SRLLIDGKLVAGTAG-TFPTVNPATEEVLGVAADADSDDMGRAIAAARSAFDDTDWSTNTELRVRCLRQLKDALREHVEE 87  Mycobacterium
WP_011782298   9 SRLLIDGKLVAGSSG-TFTTVNPATEETLGVAADASAEDMSAAIGAARRSFDETDWATNTDLRVRCIRQLQQAMRDHVEE 87  Mycobacterium v...
WP_011892497   9 SKLLIDGKLVAGSAG-TFPTVNPATEETLGVAADAGADDMDAAIGAARRAFDETGWSTDTALRVRCIRQLQNAMRAHVEE 87  Mycobacterium g...
WP_013830525   9 SRLLIDGKLTAGAAG-GFATVNPATEEVLGEAANADSADMDRAIDAARRAFDDTDWSTNTELRVRCVRQLRDAMRAQVEE 87  Mycobacterium s...
WP_005084280   9 SELFIDGKLLPGGAG-RFPTVNPATEEVLGTAADADSDDMSDAIEAARRAFDDSGWSRDVALRVHCIRQLRDGMKTHIEE 87  Mycobacterium a...
WP_020907947   9 SALLVDGKLVPGSGG-TFEVFNPATEELIGRAAEGTTADMDAAIAAARRAFDETEWARDHGFRARCLRQLCDALQSHIEE 87  Rhodococcus ery...
WP_013415347   9 SALLIDGKLVPGSGG-VFEVLAPATEEVVGHAAEGTAADMDAAIAAARRAFDETSWSRDHSFRARCLRQLRDTLQSHIEE 87  Rhodococcus equi
WP_012835528   9 SDLLIDGKQVAGSGS-TFDIVNPATEEIVGQAADATAEDMSAAIAAARNAFDTTDWSRDHALRARFLRQLRDALLAHADE 87  Gordonia bronch...
ZP_08197974   91 LRELTTAEVGASAFLVAGPQFDTPVDTLRWTIDLAESYEWSRDLGVGVTMGISSRRTVRKEAVGVVAAITPWNFPNQINL 170 Nocardioidaceae...
WP_003897260  88 LRDLTIAEVGAPRMLTSGAQLEGPIDDLAFSADTAENYPWRTDLGHATPQGIPTDRVIAREAVGVVGAITPWNFPHQINL 167 Mycobacterium s...
WP_011561955  88 MRDITIAEVGAPRMLTSGAQLEGPIDDLSFAADTAETYEWRTDLGHATPQGIPTRRTLAREAVGVVGAITPWNFPHQINL 167 Mycobacterium
WP_011782298  88 LRELTIAEVGAPRMLTSAAQLEGPVEDLSFCADTAESYAWTTDLGIASPMGIKTHRTIAREAVGVVGAITPWNFPHQINL 167 Mycobacterium v...
WP_011892497  88 LRELTIAEVGAPRMLTAAAQLEGPVDDLSFCADTAESYRWSTDLGIASPMGIKTRRTVTREAIGVVGAITPWNFPHQINL 167 Mycobacterium g...
WP_013830525  88 LRELTIAEVGAPRMLTAGAQLEGPVEDLGFAADTAESYEWTQDLGHATPLGIPTRRSVVREAVGVVGAITPWNFPHQINL 167 Mycobacterium s...
WP_005084280  88 LRELTIAEVGAPRMLTAGAQLEGPVDDLQFAADTAESFDWTSDLGVASPMGIKTRRTLAREAVGVVGAVTPWNFPHQINL 167 Mycobacterium a...
WP_020907947  88 LREITVAEVGAPVMLTNGPQLEGPIEDLRYWADLIETYSWEQDLGHASPMGIPTHRRLLKEAVGVVGAITPWNFPHQINF 167 Rhodococcus ery...
WP_013415347  88 LREITIAEVGAPRMLTAGPQLEGPIADLGYFADLAESYAWESDLGVAAPMGIRTRRRVLKEAVGVVGAVTPWNFPHQINF 167 Rhodococcus equi
WP_012835528  88 FREITVAEVGCPVFLTHGPQLEGPITDLGYFADLAETYEWTRDLGEAKPMGLKNRRELRAEAAGVVGAITPWNFPHQINF 167 Gordonia bronch...
ZP_08197974  171 AKIGPALAAGNTVILKPAPDTPWLAAELGRLAAEHTDLPPGVFNVVTPRDNRVAAMLAEDPRVDLVSFTGSTATGRAIMA 250 Nocardioidaceae...
WP_003897260 168 AKVGPALAAGNTLVLKPAPDTPWAAAVLGQIITEHTDFPPGVINIVTSSDHSVGALLSKDPRVDMVSFTGSTATGRAVMT 247 Mycobacterium s...
WP_011561955 168 AKVGPALAAGNTLILKPAPDTPWCAAAVGEIIAEHTDFPPGVINVVTSSDHAVGALLSQDPRVDMVSFTGSTATGRAVMT 247 Mycobacterium
WP_011782298 168 AKIGPALAAGNTLVLKPAPDTPWAAAVLGELIAEHTDFPAGVINIVTSSDHGVGALLSKDPRVDMVSFTGSTNTGRAVMA 247 Mycobacterium v...
WP_011892497 168 AKVGPALAAGNTLVLKPAPDTPWAAAVLGELITEHTDFPAGVINIVTSSDHGVGALLSKDPRVDMVSFTGSTNTGRAVMA 247 Mycobacterium g...
WP_013830525 168 AKLGPALAAGNTVVLKPAPDTPWVAAVLGELIAEHTDIPPGVVNIVTSTDHTLGAMLAGDPRVDMVSFTGSTATGRSVMA 247 Mycobacterium s...
WP_005084280 168 AKVGPALAAGNTLVLKPAPDTPWCAAVLGRIIAEHTDFPPGVVNIVTSSDHRIGAQLSTDPRVDMVSFTGSTATGRAVMT 247 Mycobacterium a...
WP_020907947 168 AKLGPALAAGNTIVLKPAPDTPWCAALVAKVIAEETEIPAGVVNVVTSTDHSLGAQLCSDPRVDLVSFTGSTATGRTVMA 247 Rhodococcus ery...
WP_013415347 168 AKLGPALAAGNTVVLKPAPDTPWCAALVGKVIAEETDIPAGVVNIVTSTDHRLGAQLAEDPRVDLISFTGSTATGKAVMT 247 Rhodococcus equi
WP_012835528 168 AKIGPALAAGCTVVLKPAPDTPWCAALVGKVIAEETDFPPGVINIVTSSDHALGAQLATDPRVDIVSFTGSTATGKKVMA 247 Gordonia bronch...
ZP_08197974  251 AAAPSLKKVFLELGGKSAAIVLDDAD---VASAASMAAFSVAVHAGQGCALTTRLLVPRASYDAAVEAAATTMASLGAGD 327 Nocardioidaceae...
WP_003897260 248 DAALTIKKVFLELGGKSAFLVLDDAD---LTGACSMAAFTVAMHAGQGCAITTRLVVPRARYDEAVEIAAGTLGSIKPGD 324 Mycobacterium s...
WP_011561955 248 DAAATIKKVFLELGGKSAFLVLDDAD---LAGACSMAAFTAAMHAGQGCAITTRLVVPRAKYDDAVEAAAATMGSIKPGD 324 Mycobacterium
WP_011782298 248 DGAATLKKVFLELGGKSAFLVIDDAD---LAGACSMAAFTASMHAGQGCAITTRLVVPRDRYDEAVEAAAATMGGLKAGD 324 Mycobacterium v...
WP_011892497 248 DGAATLTKVFLELGGKSAFLVLDDAD---LAGACSMAAFTASMHAGQGCAITTRLLVPRARYDEAVEAAAATMGGLKPGD 324 Mycobacterium g...
WP_013830525 248 DAAATIKKVFLELGGKSAFVVLDDAD---LAAACSVAGFSVCLHAGQGCAITTRLVVPRARYDEAVAIAAGTMGSIKPGD 324 Mycobacterium s...
WP_005084280 248 DAAATVKKVFLELGGKSAFIVLDDLDeaaLGSACSVAAFTAAMHAGQGCAITTRLVVPRERYDDAVAAAAATMGSLKPGD 327 Mycobacterium a...
WP_020907947 248 TAAQTLKKVFLELGGKSAFIVLDDAD---IKGACSVAAFSVCVHAGQGCALSTRLLVPRARYEDALAAASAAMAGIRAGD 324 Rhodococcus ery...
WP_013415347 248 AAAQSLKKVFLELGGKSAFVVLDDAD---LAAACAIAAFTVCTHAGQGCAITTRLLVPRERYDDAVAATARTMAGIRPGD 324 Rhodococcus equi
WP_012835528 248 AASESLKKVFLELGGKSAFIVLDDAD---LASACSMAAFAVVTHAGQGCAITTRLLVPRSKLDEATAITRDSLAGLAAGD 324 Gordonia bronch...
ZP_08197974  328 PAEPGTICGPVISAVQRDRILGYLALAEEEGGRFATGGTQAAqdgDLAGGFWVEPTVVAGLDNTARVAREEIFGPVLTVI 407 Nocardioidaceae...
WP_003897260 325 PTSKRTVCGPVISARQRDRVQSYLDLAIKEGGRFACGGGRPA---DMDKGFWIEPTVIAGLDNNARVAREEIFGPVLTVI 401 Mycobacterium s...
WP_011561955 325 PTSKRTVCGPVISARQRDRIQGYLDLALQEGGRFACGGGRPA---DRDTGFFIEPTVIAGLDNNARVAREEIFGPVLTVI 401 Mycobacterium
WP_011782298 325 PTKPGTVCGPLISERQRERVQGYLDSAIAEGGRFACGGGRPA---DRDTGFFIDPTVIAGLDNNAKVAREEIFGPVLTVI 401 Mycobacterium v...
WP_011892497 325 PDKPGTICGPVISARQRDRIQSYLDSAVAEGGRFACGGGRPA---DRDTGFFIEPTVIAGLDNNAKVAREEIFGPVLTVI 401 Mycobacterium g...
WP_013830525 325 PTKPGTVCGPVISARQRDRVQSYLDLALAEGGEFACGGGRPA---DQPAGFFIEPTVIAGLTNDARVAREEIFGPVLTVI 401 Mycobacterium s...
WP_005084280 328 PAKPGTICGPVISARQRDRVQSYLDLAVAEGGSFACGGGRPE---GKDRGFFIEPTVVAGLTNAARVAREEIFGPVLVVI 404 Mycobacterium a...
WP_020907947 325 PSARGTVCGPVISARQRARVESYLALAVEEGGTIVTGGGRPD---DHQSGFFVEPTLIAGLDNSSRVAQEEIFGPVLVII 401 Rhodococcus ery...
WP_013415347 325 PDERGTVCGPLISARQRARVESYLKLAVEEGGTIVVGGGRPA---EHERGFFVEPTLISGLDNSSRVAQEEIFGPVLVIL 401 Rhodococcus equi
WP_012835528 325 PTDSGTICGPVISAAQRQRVESYIELARSEGGTIEIGGGRPA---GRDRGFFVEPTLISGLDNTSRVAQEEVFGPVLVII 401 Gordonia bronch...
ZP_08197974  408 AHDGDDDAVRIANDSPYGLSGSVESGSLKRAKSVAARIRTGTIGVNGGQWFGPDAPFGGYKQSGLGREMGVEGFEEYLET 487 Nocardioidaceae...
WP_003897260 402 AHDGDDDAVRIANDSPYGLSGTVFSGDDARAQAVASRMRVGTVNVNGGIWYSADAPFGGYKQSGVGREMGLAGFEEYTEI 481 Mycobacterium s...
WP_011561955 402 AHDGDDDAVRIANDSPYGLSGTVFSGDDARAQAVAARMRVGTVNVNGGIWYSADAPFGGYKQSGIGREMGVAGFEEYTEI 481 Mycobacterium
WP_011782298 402 AHDGDDDAVRIANDSPYGLSGTVFSADPERAAGIAARMRVGTVNVNGGVWYSADMPFGGYKQSGIGREMGLAGFEEYLEI 481 Mycobacterium v...
WP_011892497 402 AHDGDDDAVRIANDSPYGLSGTVFSPDLERANGVAARLRVGTVNINGGVWYSADMPFGGYKQSGIGREMGLAGFEEYLEI 481 Mycobacterium g...
WP_013830525 402 AHDGDDDAVRIANDSPYGLSATVYGAAAQRAAAVAARMRAGTVNVNGGVWYSADVPFGGYKQSGNGREMGVAGFEEYLEI 481 Mycobacterium s...
WP_005084280 405 AHDGDEDAVRIANDSPYGLSGTVFGDDDERSARVASRLRVGTVNVNGGVWYSADAPFGGYKQSGNGREMGVAGFEEYLET 484 Mycobacterium a...
WP_020907947 402 PYDNDDDAIRIANDSPYGLSGSVWGADPDRVAHVVAGVRTGTLSVNGGVWYSADAPFGGYKQSGIGREMGLAGFEEYLET 481 Rhodococcus ery...
WP_013415347 402 PHDGDDDAIRIANDSPYGLSGSVWGTDPDRVRHVVEGVRTGTLAVNGGVWYAADAPFGGYKQSGIGREMGVAGFEEYLET 481 Rhodococcus equi
WP_012835528 402 PHDGDDDAIRIANDSPYGLSGQVWGTDEDRINKVVNGVRTGTMAINGGIWYSADVPFGGYKQSGIGREMGVAGFEEYLET 481 Gordonia bronch...
ZP_08197974  488 KLIAEPA 494 Nocardioidaceae bacterium Broad-1
WP_003897260 482 KLIATLA 488 Mycobacterium smegmatis
WP_011561955 482 KLIATAA 488 Mycobacterium
WP_011782298 482 KAIATAA 488 Mycobacterium vanbaalenii
WP_011892497 482 KAIATAV 488 Mycobacterium gilvum
WP_013830525 482 KAIATAA 488 Mycobacterium sp. JDM601
WP_005084280 485 KVIATAV 491 Mycobacterium abscessus
WP_020907947 482 KLVASPS 488 Rhodococcus erythropolis
WP_013415347 482 KLVAEPA 488 Rhodococcus equi
WP_012835528 482 KAVARPA 488 Gordonia bronchialis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap