Conserved Protein Domain Family
COG3752

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COG3752: COG3752 
Steroid 5-alpha reductase family enzyme [General function prediction only]
Statistics
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PSSM-Id: 442966
Aligned: 168 rows
Threshold Bit Score: 176.562
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012243179  31 NLQKETL-NI-LVIVCGISMAYCFIVGELSGNNSQMDKLWSIL---PIAYAWIVAVKG--SMHPRLIVMALLITIWGVRL 103
WP_013584714  45 vgGIPVF-AL-AVAAAFGIQVLVFIPSAIRRTERFFDLTGSLT---FITVSVALALLAp-AQDARGWILAAMVIVWAARL 118
WP_007640685  36 DTGLTIF-AC-CALIAFIVQWIALIPAYLLKTEHFYDLTGGAT---YLAVVIFAFIQSe-QHDLRSIILTCLVSIWAIRL 109
WP_016339188   1 meinYIFiLY-TFIISLGLNLVFFAIAFLLKSDAFTDITYALT---FVLTTSIILGWKq-NFSLFQIVLYVLVLLWAIRL 75 
WP_024269055   1 -------mLFeLLLISLGINGVFFLIAATLRSDLFTDLTYSLS---FILLSLYLGIQAp-LFHPVQYINLLLVILWALRL 69 
WP_047011497  31 alGVNSL-LL-LAGWIFLIQWLGFLHAWFTQTERYYDLLGSLT---YISATVLALGFAe-SLDVRRIILAAVVLAWAGRL 104
WP_053819450  29 fyGLPVI-LF-CAVVSFVTHWIIAVPSLITSSEKYFDFTGMIAtllVVSASIFALLSSgeEASIRAVVVATFVSVWTLRL 106
WP_008246447  33 ygGLSLP-LW-SLLIAFGVQWLAFIPAYLNHTERFYDLTGALS---NIAVVLVCFSLSv-ETD-RNYLLAGLIVIWALRL 105
WP_066636586  29 gGGLPLM-LL-LVLIAYVVNWVVYVPSYRAQTERFFDLTGSLT---FQLVAVLALVLVd-DRDARSWVLAAMVLVWALRL 102
WP_126042331  33 lgAIPLF-AL-VVAIAFIIQWIVYIHAQLNRTEKYFDLTGSIT---YTSISLFLLFAVp-DLSTRSLILGLMVMTWALRL 106
WP_012243179 104 TLNFAKKGAysfkfwAGEEDYRWIVLRKDPKlnkKwkwalfdLVFISVFQNALVLAITLPLLAVMESAm-----aFNIF- 177
WP_013584714 119 GSFLFARVH------RSGSDGRFDEIKTRPL---R-------FFQVWCIQGLWVALTASAAWIAMSADadg-rapLDGF- 180
WP_007640685 110 ASFLFLRVR------KQGSDSRFDDIKLNFW---R-------FSIAWTVQGLWVLLTSGAAIAAITSGhk---thFGWI- 169
WP_016339188  76 GTYLLIRII------KIKVDHRFDKMRNSFW---K-------FLGFWILQAISVFIIVLPTTFVLFIDgsy-fdsTNYY- 137
WP_024269055  70 GGYLFRRIL------LIKVDHRFDDRRDSFI---R-------FGSFWLLQALTVWIVMLPLAGSSVPPspgalppWGILi 133
WP_047011497 105 GMFLFKRIV------AAGKDSRFDDIKPYWY---R-------FLMAWTLQGLWVFLTLSGVLICLLAKts---laIGYL- 164
WP_053819450 107 GIFLYKRIV------KAGEDRRFRDIKKSLP---K-------FLMTWTLSALWVFLTTVNAITIIALNpl---epVGVF- 166
WP_008246447 106 GGFLFWRVC------VDGRDTRFDKIKINFY---R-------FLVTWTLQALWVFLISLAAILAMASGvd---kpLGWT- 165
WP_066636586 103 GIFLFRRVS------KAGKDGRFDELKKDWR---R-------FLVVWTTQGLWVTFTAGAALAAITSGdr---epLGVL- 162
WP_126042331 107 GPFLFLRIR------KDGGDSRFDELKKTPI---R-------FFNVWNIQGLWVTFTASAAWIGMTSAdq---epIGWL- 166
WP_012243179 178 DGLIAALLLGFIILETIADRQQMSFQTKKYsllkegkslkdlpapYNLGFNTQGLWERSRHPNYFSEQAIWIVLYLFTIs 257
WP_013584714 181 VIAGVIVWLLGMALEVVADLQKQAFRADPA---------------NDGEFIRTGLWSRSRHPNYFGEILVWIGVFLVAA- 244
WP_007640685 170 GLVGLVVWSIGFSIEAIADNQKRIFKQQKN---------------THSDFIQTGLWSRSRHPNYFGEILLWVGVAIIAY- 233
WP_016339188 138 TFIFVGISLFGLLYETIGDAQKFIFFQN-----------------KKGEFIQTGLWKNSRHPNYFGEIVFWMFLTIAFLf 200
WP_024269055 134 SAAGWAGFAAGLIIQWIADRQKFAFKSREE---------------NSGKFMKDGLWSRSRHPNYFGEMLIWWGLGIASV- 197
WP_047011497 165 GVLGLLVWLAGFVIEVFADAQKQEFRKNPA---------------NRQQFIHSGLWAWSRHPNYFGEIVMWLGVALMAL- 228
WP_053819450 167 FVLGTVLWLLGFGFEVVADRQKKHFSEQPE---------------NIDRFISHGLWSVSRHPNYFGEIILWTGIAIISL- 230
WP_008246447 166 AGIGFLCWLLGMVLEVAADVQKRRFRADLR---------------NQGQFIRQGLWAWSRHPNYFGEILVWIGVCIIAF- 229
WP_066636586 163 GYAGILVWLAGIGFESVADAQKSAFKADPA---------------NEGEFIRTGLWSISRHPNYVGEILLWTGVALVAV- 226
WP_126042331 167 FFVGAALWLVGFTIEVTADMQKRIWRRKPE---------------NKGRYITSGLWAWSRHPNYFGEITLWLGIALIAL- 230
WP_012243179 258 agVA-SyIFf--------nWTLVGAMVLILLF--MGSSLFSENISLSK---YPMYKDYIHKVSKYVPLRRYN 315
WP_013584714 245 --PV-LqGWq--------wVAVLSPLFVILLLtrVSGIPLLEKRADERwgdRADYRAYRDRTPVLIPALTAR 305
WP_007640685 234 --PA-LnEWq--------lVTLVSPIFVIVLLtkISGIPMQEEQAQKRwkdNQAYQDYKKRTPVLIPKLFG- 293
WP_016339188 201 --NLiLkNYsdnkmillqlLWLLSPLYILLLLnfVSGLPLLEISAYKKlkdNAAYQTYVQKTSAIIPYCGKK 270
WP_024269055 198 --PF-FrSHe--------fLYFAGPLFITLMLryVSGVPLLEKQADKKwgeKPEYRDYKARTPLIIPRILPA 258
WP_047011497 229 --PV-FaGWq--------yLGLVSPLFVYLVLtkISGIPMLEKSAESRwgdDPAYQAYVRDTPVLWPKAPRS 289
WP_053819450 231 --PF-LsSWq--------fVSLVSPLFVFLLLtkISGLPFLEEKAEKKwgkDKAYVEYKNKTPILIPFFGKR 291
WP_008246447 230 --PA-LsGCl--------yLGLLSPLFVILVLtkVTGIPLLEASANRRwgsDPNYQQYKAQTPLLIPRIPRP 290
WP_066636586 227 --AP-LsGWq--------hVTLVSPVLIYLLLrfGSGVPALERRADERwgdREDYQAYKASTPVLFPFGAR- 286
WP_126042331 231 --PN-LsGWq--------yIGLLSPVFVVILLtrISGIPLLEKQGEERwgdEEGYRDYVARTPTLIPLPPRR 291
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