2ISM


Conserved Protein Domain Family
GSDH

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pfam07995: GSDH 
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Glucose / Sorbosone dehydrogenase
Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.
Statistics
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PSSM-Id: 429776
Aligned: 77 rows
Threshold Bit Score: 269.041
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2ISM_A         30 LEVP---WAL------AFLPD-GGM-LIAER-PGRIRLFR-EGRL--STYAEL----------SV----------YHRGE 74  Thermus thermo...
Q1H3Y7         78 DQYPtgpFEMlgnkhfLFITKcGEVyFTRINeSGEIEITKnADSLtkPGLDEReeskgddydgLV----------YCKEL 147 Methylobacillu...
jgi:Noca_2041  50 LDHP---WDV------RPIGD-GRL-IFTQRdRATVSIWD-GSRT--RLVQGFp--------sDSv---------WVSGE 98 
Q2LUD0         82 LNVP---WSL------VFLPD-KRA-LVSER-SGKIRLII-NGKLesHPYATV----------DA----------VRIGE 128 Syntrophus aci...
jgi:Nmar_1561  49 LEKP---RSI------AVS-D-NRI-FVTEK-DGSIVVIE-NDIQleSPLATF----------RS----------ANVFD 94 
ABK78628       76 LDEP---RHL------AFYGD--RV-FLTEK-AGRVRVVQ-DDVLleEPLAVL----------RV----------ADELD 121
jgi:Nmar_0371  47 LKIP---WGI------DFAQD-GRI-FFTER-PGTVNVIE-DGQV--SQIMSR----------GV-----------GGGE 90 
Q5UZS0         96 LEIP---WDL------SFAAD-GTL-FLTER-VGRVLSFV-DGSV--RTVTEPa--------aVIdaessddgwwVTGGE 152 Haloarcula mar...
jgi:Pmen_0465  33 LEHP---WSL------AFLPD-GRI-LVTER-VGRLRIVEaDGSLdpDPVAGLp---------EI----------FVAAQ 81 
Q0ALD1         30 LEYP---WSL------AFLPD-GRM-LVTEK-PGRLRIID-ESGLvqTPVSGVp---------EV----------FYSGQ 77  Maricaulis mar...
2ISM_A         75 SGLLGLALHPRFPQEPYVYAYRTv---aEGGLRN-QVVRLRHLGE-----RGVLDRVVLDGIPA-RPH--GLHSGGR-IA 141 Thermus thermo...
Q1H3Y7        148 AGVKDSLLVGN-----TLYVVYTtwdheANGARL-AVSAFELDQEq---sELTFSKDIFLTYPAvKEPflGHQVGGK-LV 217 Methylobacillu...
jgi:Noca_2041  99 TGLMGLEVDPSFASNRTFYTCQGgf-taGGGHDV-RIIRWTLRDDl---vSISGSKRLLGGLPA--TS--GRHGGCRlLA 169
Q2LUD0        129 AGLMGLAMHPRFPAEPYIYAMYTeq--kKGALRN-RVVRFRDhg-----rTGSFDRVILDDIPG---G--RFHDGGR-IA 194 Syntrophus aci...
jgi:Nmar_1561  95 GGLLGIDLHPNFAENHYLYVFLTye--eDEALWN-KILRITESEN-----KLQDAETIFDKIPG---S--SFTNGGF-IK 160
ABK78628      122 SGLLGIAVHPDFGENHKLYVYHSyi--eDGAAWN-RILQITERDN-----KLEDAETVLDKIPG---S--RFSNGGV-IK 187
jgi:Nmar_0371  91 GGMLGIALDPEFEKNHYVYVYYTyn--eLLGIKN-RLVQYVESDN-----KLNHEKILLEDIPG---A--PYHDGGR-IK 156
Q5UZS0        153 GGTLGVAAHPTYPDPPVVYVYYTt-----mTDDDeRVNRVVAMDVsaedpAAT-ESVLVDNIPG---S--KIHNGGR-LT 220 Haloarcula mar...
jgi:Pmen_0465  82 AGLMEVALDPDYVSNRWLYLSYAhg--tTQANNT-RLARARLVDD-----ELRDFEVLFTAQPL-KAG--ASHYGGR-IA 149
Q0ALD1         78 GGLLDVVLSLDFETDGLVYLSWSgg--sAGDNTL-YLGRGRLEGD-----ALVEFDVLFEAMPH-RRT--DVHYGGR-MA 145 Maricaulis mar...
2ISM_A        142 FGP-----DG-MLYVTTGEVYE-RELAQDLASLGGKILRLT-PEGEPAPGNPFLgr-rgARPEVYSLGHRNPQ-GLAWHP 211 Thermus thermo...
Q1H3Y7        218 LGA-----DDdTMFLSVGDFSK-PDGVQDPSTALGKMIKINlKDASA---------------EIYASGLRSPSgGLYFDR 276 Methylobacillu...
jgi:Noca_2041 170 VGK--------RLYAGTGDAAT-GSTPENKKSLGGKTLCLLaATGKPCGSNPFAgsknhNKRYVHTYGHRNVQ-GLDRRR 239
Q2LUD0        195 FGP-----DG-MLYVTTGENFN-ADLAQDRSSLAGKILRIS-PDGEIPADNPF------KDSPVYSYGHRNPQ-GLAWQP 259 Syntrophus aci...
jgi:Nmar_1561 161 FGP-----DG-KLYVGTGATSDsSHLPQDLDSLSGKILRIN-DDGSIPDDNPF------SNSPVYSLGHRNPQ-GMTWDN 226
ABK78628      188 FGP-----DG-KLYVGTGSVSDtLHLSQEMDSLGGKILRIN-DDGSIPSDNPF------EGSPVYSLGHRDPQ-GMAWSS 253
jgi:Nmar_0371 157 FGP-----DE-MLYVTTGDAVE-PELSQNLNSVAGKILRIK-SDGTIPEDNPF------GSA-IYSIGHRNPQ-GIAWD- 219
Q5UZS0        221 FGP-----EN-YLWITTGDAGD-GELSADTDSLGGKVLRVT-PAGDPAPGNPELg----GDPRVFTYGHRNPQ-GLAWLP 287 Haloarcula mar...
jgi:Pmen_0465 150 FLA-----DK-TLVLTLGDGFDwREEAQNLANHLGKIVRLN-RDGSVPADNPLVgq-tgAAAEIYSLGHRNVQ-GIVFDA 220
Q0ALD1        146 MIPaeagqAA-TVVMGVGDGFDyREEAQNPGTHFGTYVRLG-LDGQ-PAQRVFEn----SAPGVISIGHRNPQ-AVVYDA 217 Maricaulis mar...
2ISM_A        212 KTGELFSSEHGPSGEqgy-ghDEVNLIVPGGNYGWPRVV----------GR--------GNDPR-YRDPLY-FWPQG--- 267 Thermus thermo...
Q1H3Y7        277 DSNELWETEHGPKGG------DEINLIKQGRNYGWPLVSygtlyeregmGNyyg--nkyNSHED-FEKPAF-VFNPS--- 343 Methylobacillu...
jgi:Noca_2041 240 D-GTLWSVEQGSYRD------DEVNRLRKGGDYGWNPVP----------GYdesvpmtdQSLPGrQRAA---VWRSGdpt 299
Q2LUD0        260 ETGRLFESEHGPSGEfahfghDEINRIVKGGNYGWPLVI----------GA--------PEIQP-YIDPLI-VWKEA--- 316 Syntrophus aci...
jgi:Nmar_1561 227 N-GNLYVSEFGPEKN------DEINIILAGKNYGWPEQEc-------------------SGNES-FENAVL-CYDPS--- 275
ABK78628      254 D-GTMYASDLGPSKN------DEINVIIPGGNYGWPDHE--------------------CSGGG-YEDSIL-CFDPA--- 301
jgi:Nmar_0371 220 KSGNLIATEHGPSGWrgv-ahDEINWIVSGANYGWPDVI----------GD--------ETLEG-ATNPILhSGDDT--- 276
Q5UZS0        288 D-GTLVASEHGPTGR------DELNRLEAGGYYGWPDTRkha--------------eylDADPE-VRRPLAnTGNTGg-- 343 Haloarcula mar...
jgi:Pmen_0465 221 EAGRLYSHEHGPRGG------DELNLIEAGNNYGWPLATfgi----dytGArvs---pyTELPG-LTQPLL-HWTPS--- 282
Q0ALD1        218 TNHVVWSHEHGPRGG------DEINELSSTANYGWPITShgv----dytGAlvt---pfDTYAG-IDEPIH-VWTPS--- 279 Maricaulis mar...
2ISM_A        268 FPPGNLAFF---------RGDLYVAGLR-------GQALLRLVL-EGErgr----------------wrVLRVETAL--- 311 Thermus thermo...
Q1H3Y7        344 IGVGAIAKYpktgkneywEGGFFVAGMA-------ANSLLYMR--KEGe-------------------rLVYAEPVL--- 392 Methylobacillu...
jgi:Noca_2041 300 LATSGGGFVygkr-wgalDGSFAVAALK-------AERVLFLQL-SASgr-----------------lqRVRVPAALr-- 351
Q2LUD0        317 TPPGGIAFYngtf-lphlKGDLFVATLK-------SRALIRVRF-DGDt-------------------kISRIERWFstd 368 Syntrophus aci...
jgi:Nmar_1561 276 IEPGGILYYtgdk--fdfEFPFIMASMR-------ASNVYQVDF-DEG---------------------LSSQKSIL--- 321
ABK78628      302 IEPGGLVVYsgeq--lefGGSLIMTSLR-------VGSLYGFDPtDGG---------------------LEDRQSIL--- 348
jgi:Nmar_0371 277 WAPSGSTFYygdd-mpmfDGKYFVAALK-------GQHIHVIEF-DESy-------------------nVLFHGELFs-- 326
Q5UZS0        344 WAPSGSLFYtgda-vpslRNRLLTGGLN-------GQTLLVTTLtPAGadlppgadaevydadwtddayTATTHSLLa-- 413 Haloarcula mar...
jgi:Pmen_0465 283 VAPASLTQYrgal-fpdwQGDLFAATLA-------ERSVRRVRLhEg---------------------mLAGEEILF--- 330
Q0ALD1        280 IAPAGMALYrgem-fpewDGDLLVAALIpgdadvpSGHVRRVEL-D-Ag-------------------qVVGEEVLF--- 334 Maricaulis mar...
2ISM_A        312 ---SGFG-RLREVQVGPDGALYVTTSnrDG---R 338 Thermus thermophilus HB8
Q1H3Y7        393 -----HDyRIRALKIDKNGRFFIKTDn-DQflwm 420 Methylobacillus flagellatus KT
jgi:Noca_2041 352 ----QHG-RIRTVVDGPGSVAYVTTDngNG---N 377
Q2LUD0        369 fkkGKYG-RLRDVVTGPDGAIYFTSSnrDG---R 398 Syntrophus aciditrophicus SB
jgi:Nmar_1561 322 ---SGIG-RVRDVVQGPDGYLYVITSntDG---K 348
ABK78628      349 ---AGLG-RIRDVDEGPDGYLYALTSntDG---R 375
jgi:Nmar_0371 327 ---GEFG-RIRDVANGPDG-LYFMTSnqDG---R 352
Q5UZS0        414 ---NEIG-RIRHVEQGPDGGLYLVTSnrDGragD 443 Haloarcula marismortui
jgi:Pmen_0465 331 ---EELGeRIRDVRAGPDGALYLLTDnaDG---R 358
Q0ALD1        335 ---GEIGaRIRDVRVGPDGAVWLLTDeaEG---R 362 Maricaulis maris MCS10
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