Conserved Protein Domain Family
dinG_rel

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TIGR01407: dinG_rel 
DnaQ family exonuclease/DinG family helicase, putative
This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Statistics
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PSSM-Id: 273602
Aligned: 5 rows
Threshold Bit Score: 1091.38
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010897852   4 RFVVIDIETTGQSVAQgDRIIEIGAVVIEDEEAVESFCTLVNPERSIPPFIEELTGISDEMVKGAPTFHQCIPELMSMLE 83   Bacillus halod...
WP_002382784  12 VYAVVDLETTGTDPTS-DRIIQFGCVLVQDGKIIANFATDVNPNQVVPKQIQSLTGISNTQVQKAPYFEDVAHTIYHYLE 90   Enterococcus f...
WP_000525079   5 TYAVVDLETTGNQLDF-DDIIQIGITFVRNNQIIDTYHSMIRTNLEIPPFIQALTSIEENMLQQAPYFNQVAQEIYDKIK 83   Staphylococcus...
WP_031296544   3 RYAVVDLEATDAHSSE-NKIIQIGIVLVEDGEIVETFSTEVNPHEPLLPRISELTGLSDKQLKTAPEFSEVAAKVRELLT 81   Lactococcus la...
WP_000848722   7 RYVVVDLEATSTG-SK-AKIIQVGIVVIEDGEIVDHYTTDVNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVE 84   Streptococcus ...
WP_010897852  84 GGVFVAHNVHFDLSFLQKLLEHEGYGPLLVPIIDTVELSRILLPTEESYKLSALTEQLGLEHENPHRADSDAKVTADLLL 163  Bacillus halod...
WP_002382784  91 DTIFVAHNVHFDYNFLARELVRCGTPPLTIPAIDTVELAQIFLPTEKSFRLSDLSESLGLSHENPHQADSDAQVTAELLL 170  Enterococcus f...
WP_000525079  84 DCIFVAHNVDFDLNFIKKAFKDCNIQYRPKKVIDTLEIFKIAFPTDKSYQLSELAEAHGITLANAHRADEDAATTAKLMI 163  Staphylococcus...
WP_031296544  82 DSVFVAHNARFDYGLLEKSFLNAGLEFNEMLRVDTVDLARVFYPTFEKYGLESLSEKLDLAHDHPHAAVSDAYATAELLL 161  Lactococcus la...
WP_000848722  85 DGIFVAHNVQFDANLLAENLFFEGYE-LRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAELLL 163  Streptococcus ...
WP_010897852 164 LLLQKLRQLPLMTLQQLELLSDSWISDMGPILRQLIEKKMHDHAREEevFDIYRQLAIRKPVKMKPQEEEII-TTTDTFQ 242  Bacillus halod...
WP_002382784 171 LIQEKMKSLPLVTMEKIAELSQQTARETSAFIQQTYEQMKKQVTPLNpaYQVVSGIALRKKEVPLFEETFYQ-TSTYPKT 249  Enterococcus f...
WP_000525079 164 LAFEKFEKLPLDTLKQLYYLSKQLKYDLYDIFFEMVRQYDAKPLDKS--YEKFEQIIYRKQVDFKKPTTNYNgSLKSLYS 241  Staphylococcus...
WP_031296544 162 KIEAKIQKLPRSVLEELLRHSDNLLFESKTFLQEQLDKTKIRPA--G--FKVVHNIATRKFRASVSKKSPLT-ALSANFS 236  Lactococcus la...
WP_000848722 164 FLRKKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPD---LVQVQGLYFKKTEASLEPRK-----LSQDFS 235  Streptococcus ...
WP_010897852 243 SFKDRITQeggslskafltyE----WRQGQLKMMEVVHEAFSN--NEHVLIEAGTGTGKSLAYLLPAAYFAH-MEKaPVV 315  Bacillus halod...
WP_002382784 250 KKAKEKLF------------GerfaYRAEQSRMMNLVYDHFTEgtTKDLFIEAATGTGKTLGYLLPMSYLAT-PEK-PVI 315  Enterococcus f...
WP_000525079 242 KAVDQLGL------------T----YRPQQLYLAETILDQLMH--SEKAMIEASLGSGKSLAYLLAALMYNIeTGK-HVM 302  Staphylococcus...
WP_031296544 237 ENISRLGL------------S----SRSKQEKLAHLMETELTH--LQASFIEAPTGLGKTYGYLLPILAS----GK-GLV 293  Lactococcus la...
WP_000848722 236 KNISLLNL------------E----VREEQESFAKEVGLLLKD--EPVSLIQAPTGIGKTYGYLLPALSQSK--ER-QIV 294  Streptococcus ...
WP_010897852 316 ISTQTIPLQSQLLERDIPLLQKILPFPINVALLKGRNHYLSLWKFEQALARGceQDSYDTILAKAAILVWLTETERGDRE 395  Bacillus halod...
WP_002382784 316 ISTVSIVLQNQLVEKDLPLANQICQGKLRGIVIKSHRHYLDLQCFKATLNQP--TPQKQYALYQMGVLVWLLETETGDLD 393  Enterococcus f...
WP_000525079 303 ISTNTKLLQSQLLEKDIPAMNEALNFKINALLIKSKSDYISLGLISQILKDD--TSNYEVNILKMQLLIWITETPSGDIQ 380  Staphylococcus...
WP_031296544 294 VSTATKVLQKQLVNDVAPKLGKTFG--LKMAKIVGTKNYISLRKFSELLLNN--TDGKNFEIFKMKILIWLTETRTGELD 369  Lactococcus la...
WP_000848722 295 LSVPTKILQNQIMEEEGKRLKEVFH--TDIHSLKGPQNYLKLDAFYHSLQEN--DENRLFRRFKMQVLVWLTETETGDLD 370  Streptococcus ...
WP_010897852 396 ELNLPTGPGSFWATVESDGvsSLGKYDPWFSRCFYQRARTQAAKADLIITNHALLCTDMVQKNGLLPSFKQAVIDEAHHF 475  Bacillus halod...
WP_002382784 394 ELQLTNLNHLFWKEVTHRGldFLSKKDELYEVDFLRHLYKKVAQSNVLIVNHAFLAQESLRKQPLLPESPWLIIDEAHHL 473  Enterococcus f...
WP_000525079 381 ELNLKGGQKMYFDQKIET-----YVPAR-HDVHYYNFIKRNAQNIQIGITNHAHLIHSDVEN-SIYQLFDDCIVDEAHRL 453  Staphylococcus...
WP_031296544 370 EVSKVMTNDDYFEVIRHDG--YVNTKQLHYEQDFWLKAQKEAEQAEIKVVNHAYLIERLADYPETFLENRVLVVDEAQQL 447  Lactococcus la...
WP_000848722 371 EIGQLYRYQHFLADLRHDG--NLSSQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPE-FVSDRLLIIDEVQKI 447  Streptococcus ...
WP_010897852 476 EEVASDHLGKQTDYYSLYYFIQRLgyGDKEGLLDRMFQLAAKEDVKLT-------------------------------- 523  Bacillus halod...
WP_002382784 474 PDIASRMASERVNSVILKKQVTHF--IEKEQLFVALQQIFQQFSEEQR-------------------------------- 519  Enterococcus f...
WP_000525079 454 PDYALNQVTNELSYADIKYQLGLIgkNENEKLLKAIDQLEKQRILEKLdiapidifglkasmneihelneqlfstiftii 533  Staphylococcus...
WP_031296544 448 FPIMENAGQKSLKITDELIKIDAEt-sENPQLTKRLQESLVFQLNKK--------------------------------- 493  Lactococcus la...
WP_000848722 448 LLALENLLQETYDIQSIIDLIDKAlvGEENRVQQRILESIRFECLYLI-------------------------------- 495  Streptococcus ...
WP_010897852 524 ----------------V---------------------------------------------DEEkVKTILQECQLELDE 542  Bacillus halod...
WP_002382784 520 ----------------FvkiyqqglldfvdewqdflfelhrlfsktqkridhqellltkeriDYL-SAAGEKHSQTLQLL 582  Enterococcus f...
WP_000525079 534 ndsdvydddihrfhnvF---------------------------------------------TFE-TKDILKDLHAIIDK 567  Staphylococcus...
WP_031296544 494 -----------------------------------------------------------------------------ELD 496  Lactococcus la...
WP_000848722 496 ----------------E---------------------------------------------QFQ----SGKSRKNILDS 510  Streptococcus ...
WP_010897852 543 LfrmlhryvlqnrsssksdvgrlsyryesfreqgtlweailesgmrvhlmmkegIKKLQLVLTCFHDVYDQLSFFDQGLL 622  Bacillus halod...
WP_002382784 583 L-----------------------------------------------------QELLTIQSKLQQTIMSQLETFSLADR 609  Enterococcus f...
WP_000525079 568 L-----------------------------------------------------NKTLEIFNGISHKTVKSLRKQLLYLK 594  Staphylococcus...
WP_031296544 497 L-----------------------------------------------------NKIKIDADELGLRNLSALLEADN--- 520  Lactococcus la...
WP_000848722 511 L-----------------------------------------------------DNLHQYFSELEVEDFDELVRYFTA-E 536  Streptococcus ...
WP_010897852 623 TDAKGVIDRLQEEennlyelllesdpnAVYWIEIEPRGAKNATFLYSRPIEVGESLADRFFATKKSVVLTSATLSIKGSF 702  Bacillus halod...
WP_002382784 610 IVFVRLFQFFDEIerihhcftiylddwRPRWVKEYLPQNEDHGLIEIHDLEASLLPETKWYPRYERIIYTSGTLKFGNNK 689  Enterococcus f...
WP_000525079 595 DKFKNIEQSLKAG--------------HTSFISIKNLSQKSTIRLYVKDYAVKDVLTKQVLEKFKSLIFISGTLKFNHSF 660  Staphylococcus...
WP_031296544 521 -------------------------------------QIVWRENGMLYASDQDFYNFERLIPKNTKLFMLGATLSLSKDK 563  Lactococcus la...
WP_000848722 537 GDYW-----------------------------LEVTETSQKKIQ-ISSTKSGRTLLSSLLPESCQVLGVSATLEIS-QR 585  Streptococcus ...
WP_010897852 703 DYQMERLGLHDFGVRTEsiPSPFSYKEQARLLLPTDIPAIKDVSEEEYAQEVAIKIWRIADCSSGRILVLFTSYEMLKQV 782  Bacillus halod...
WP_002382784 690 KYLPQRLGLTEVTFKTL--PTPYNYAENARVYVPEEAVAIQNASSYEMGQYISDTIEKLMAQEERSMLVLFTSHELLSTV 767  Enterococcus f...
WP_000525079 661 EAFKQLFN-KDVHFNTFevNTSLQSAKNTSVFIPSDVASYQYKNIDEYVASIVSYIIEYTTITSSKCLVLFTSYKMMHMV 739  Staphylococcus...
WP_031296544 564 PSFPDLLGFTDYRFFKIe----GNQATNQQLLTVTDAPNIKNLSLIDYADYTANSIGELSKLNLP-MVVLFTSKMALTFV 638  Lactococcus la...
WP_000848722 586 VSLADLLGYPEAKFVKIe----SRGKQEQEVVMVKDFPLVTETSLEVYAREVAALLVEIQAFQQP-ILVLFTAKDMLLAV 660  Streptococcus ...
WP_010897852 783 YQYVKDLSMDDSLALIGQGITsGSRAKLMKAFKLHEKAILFGTSSFWEGIDLPGNELRCLVIVRLPFAPPDQPLLKAKLD 862  Bacillus halod...
WP_002382784 768 YHQVQPRLLEKGQEVLAQGIS-GSREKILKRFSNGKPNVLLGADSFWEGVDLPGTALQLLIVTRLPFENPKRPLVQAKYA 846  Enterococcus f...
WP_000525079 740 QDMLNELPEFEDYVVLTQQQN--QNYKIVQQFNNFDKAILLGTSTFFEGFDFQANGIKCVMIAKLPFMN-KHN--AKYWL 814  Staphylococcus...
WP_031296544 639 AEKLSA----EGFEILAQDIN-GSPAQIKKKFDKGEGKILLGLGSFWEGVDFDKQNQVILVIPRLPFATPDDILTKKYAQ 713  Lactococcus la...
WP_000848722 661 SDLLT-------VSHLAQYKN-GDVHQLKKRFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQ 732  Streptococcus ...
WP_010897852 863 KAEEEGKNPFRHISLPQAIIRFKQGFGRLIRTSQDKGSVFVLDKRIATTRYGRAFLESLPDVPVYKGT---LESLIEAHK 939  Bacillus halod...
WP_002382784 847 YLEAEGIQPFAQEAVPKAALRLRQALGRLIRSEEDRGALLILDRRLVTAKYGKRLIKAFPKGLSVKEAp--MPEILEELK 924  Enterococcus f...
WP_000525079 815 MDS-EFTSTFKEYVLPDAVTRFRQGLGRLIRNENDRGIIVSFDDRLINSNYKNFFEQTLENYRQKKGDiqqFGKLLRQIQ 893  Staphylococcus...
WP_031296544 714 KFE----NPFYDFNVPMATLKLRQAIGRVNRRKNQYSSIVVLDKRLAGKSYAKRMRKNLSETLPVKMLn--LLDTISEIK 787  Lactococcus la...
WP_000848722 733 ELNQEGKNAFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVKTIs--RSEVDEAID 810  Streptococcus ...
WP_010897852 940 EWM 942  Bacillus halodurans
WP_002382784 925 EFL 927  Enterococcus faecalis
WP_000525079 894 KKK 896  Staphylococcus aureus
WP_031296544 788 NFL 790  Lactococcus lactis
WP_000848722 811 RFF 813  Streptococcus pneumoniae
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