Conserved Protein Domain Family
Abhydrolase_9_N

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pfam15420: Abhydrolase_9_N 
Alpha/beta-hydrolase family N-terminus
This is the N-terminal transmembrane domain of a family of alpha/beta hydrolases which may function as lipases. The C-terminal domain (pfam10081) is the catalytic domain.
Statistics
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PSSM-Id: 434705
Aligned: 81 rows
Threshold Bit Score: 120.754
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4JU26                  46 TPSLLPRDWLFQGVVAGISGGTGYTVGVFIHWLWEVFLQrrfsepmgrgrrkalglleklqiKLELSDRGMSklknGLEI 125 Coryn...
Q8FLV5                  66 SPSLLPRPWWVTAVNLAVCQAVGHGVATGVSTLAPRVP--------------------------------------GLGQ 107 Coryn...
Q8NLM9                  73 SPSLLPKPWWVTAANLAVLQAVGHAAATGIHSIL-----------------------------PRTNRRVSR----KIYN 119 Coryn...
CeBiTec:B841_12140      59 SPSLLPRPWWVTALNVAFCQGFGHAAATGVRFTVSRGFDl---------------------vGWRPRARVTQ----RTHE 113
cebbi:cauri_2404        77 SPSLLPRPWWVTAANVAIGQGAGHLAATTAAFAAKRALHh---------------------aGRRPQDRVGP----TTRR 131
CeBiTec:A605_13265      66 SPSLLPRPWWITAANVAICQGVGHVTAAGAAWGLGKLTAa---------------------aGRRPPTHLTT----PSLS 120
Q4JYD0                  73 SPSLLPHPWWAVAGNASTSQAVGHLNGTIIANAVLPAFRa---------------------aGLDLRELVNKpgyrEAYR 131 Coryn...
WP_025253821            61 TPSLLPRPWWSIALSVGAAQVLGHAGGAALGHATGRPRRv-----------------------------------sAHPT 105 Coryn...
lgeUNICAMP:PACID_25820 102 SPSLIPRTWWMILINVAMSMLFAYGVGHLIGYLLRRFSVli-------------------dlQITASARAVR----IIRW 158
goetting:NONO_c57350   437 wPGLLPRTSIAQALLTAILILVSLTVAGIVRKILRRFGSdter------------------------------rlgKYRL 486
Q4JU26                 126 GFVTAVILALLVWVSFAVRWQQELAHLMDAEA-YTAAEFLLVLPIGIGLWALIVLAGKGLLWLIEALEdGPVGRRLGGVS 204 Coryn...
Q8FLV5                 108 ITHSAVGAITLATVAVGVQRQRNQSHLMGIKN-RGPVETALGVLVGTVGYGALLVLGELIQGAVDRLR-ALAVRMLPSWI 185 Coryn...
Q8NLM9                 120 ATHIATGAITLTTTVVGLIRHRTQIRLIGQKN-FGPKETIAGISVGTLGYGALLITGELTQHSINEVK-LLIERFLPPWI 197 Coryn...
CeBiTec:B841_12140     114 VLHAVMGTVTATVTVTSLLRQEQQAQLVSTPGrEGRRDAVAGLLVGTLGYGALLLVGETAQQSINRMS-RTLSRWLPPVV 192
cebbi:cauri_2404       132 FSYYLLGLGTFIAGIRSLRNQTEQARLVGKLNdRGPQSAALGMVAGTAGYGALLIVGEAAQLTVTQLS-LQVQRWLPRWI 210
CeBiTec:A605_13265     121 TTHVTLAAVTAVAAVLSLRRQGQQADLIGARNrRGPRHALVGTAVGTVGYGALLLLGEAAQQGVDRMS-RRLGYFLPPWL 199
Q4JYD0                 132 AIHAAFTLATAVAAYRFYKRQGESAALVNSQR-LGAPSAFVGVAVSTLGYGAFLLLGELLQSSFDLTR-HSLRRFVPAPV 209 Coryn...
WP_025253821           106 ALDLALSSITFTLSLRSYARQHQQAALVTGRQ-TGARAAMLGVGLGTVGYGGCLLGGEMVQFVFDGTV-RLLRHRIPDWL 183 Coryn...
lgeUNICAMP:PACID_25820 159 LGYAVVLAVTVSVWFWAIQQQRDVSRTVNLQR-HFWLTQIFGALTGILAFVAVLLLIRTISHGLRRLY-SGVHRFITQPV 236
goetting:NONO_c57350   487 WIAAACAVAVTGALAHAWLWQNRLRAAMEFPA-AGPMYWLHWALGTTAVLIPVLLVVRGLRWAAAYVG------------ 553
Q4JU26                 205 ---RPLFAWLAVGMALLFLVDTVVPGTVVSATERVFSVRDQEIREDLKQPQVPERSGSPQSPNKWEDLGAFGTRFVGLG 280 Coryne...
Q8FLV5                 186 rwlSWPLSVCALSTAVMLLADRVVLRRMLNTAARKAEHLNRLVFPGTWQPWEPERSGSPWSHEHWGAVGSQGRAVLSGG 264 Coryne...
Q8NLM9                 198 ---SFIAAVSVITLTTLTLADRVLLRRILHNSAIQAAHLNRMVFPGTEQPWEPERSGSPWSYEKWGAVGSQGRAVLSGG 273 Coryne...
CeBiTec:B841_12140     193 ---SWPLALVALVLVLGVTSDRFVIRRLLNSVGRSAQERNLSIFPGTVQPWEPERSGSPWSHEPWYALGSQGRALVSGG 268
cebbi:cauri_2404       211 ---AWPLAGGAVGFAAAVASDRMVWRRLLRKATIQGLALNKLVYPGSVMPWEPERSGSPWSHEQWTAVGSQGRVFLDRG 286
CeBiTec:A605_13265     200 ---SWPLAAATVGALAGVASDRVLLRRFLARAARQAELVNRAVFPGTSMPWEPERSGSPWSLEAWTAVGSQGRALLSGG 275
Q4JYD0                 210 ---AVPVAAGAVGVIAYLISDKILLRQFLEKFNEKAELVNRRVYWGYQQPWEPERSGSVWSHERWISLGAQGRVVVGGG 285 Coryne...
WP_025253821           184 ---AGMIAAAGIGWLAFVLSDKVLVTRVISTLTRRAQQLNLLVFQGTRQPWEPERSGSPWSFEPWTAVGSQGRAVLSGG 259 Coryne...
lgeUNICAMP:PACID_25820 237 ---LATSVFVIALVLALLATNNVVVRTAANAVAHQMETVNRRTTEGVHRPTSPLRSGGPGSTRSWASLGRKGQDFVASG 312
goetting:NONO_c57350   554 -----RLRSVALVTATVFACQFALLPAVVNWQRSTFATADAAMDRDVVQPVSFTRSGSPESAVQWSSLGAEGRKFVSEr 627
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