Conserved Protein Domain Family
gcvT

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PRK00389: gcvT 
glycine cleavage system aminomethyltransferase GcvT
Statistics
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PSSM-Id: 234742
Aligned: 513 rows
Threshold Bit Score: 417.981
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
14521302    1 MAKRVHLFDWHKEHAKKIEEFAGWEMPIWYSSIKEEHLAVRNAVGLFDVSHMGEIYFRGKDALKFLQYVTTNDISKPPAI 80 
46198456    1 -MKKTPLYEAHLRLGARMVDFAGYLLPLQYTSIVEEHLAVRRAVGVFDVSHMGEFLVRGEEALAFLQWATANDAGKLKVG 79 
55980492    1 -MKKTPLYEAHLRLGARMVDFAGYLLPLQYTSIVEEHLAVRRAVGVFDVSHMGEFLVRGKEALAFLQWATANDAGKLKVG 79 
157364810   1 -MRRTPLYESHVSLGAKMIDFAGWEMPLQYTSINDEVATVRKNVALFDVSHMGEIFVEGEDTVEFVDYLLTNSFKNLRIG 79 
222099448   1 -MKRTPLYERHVALGAKMVDFAGWIMPLYYSSIFEEVMAVRKSVGVFDVSHMGEIVVEGQETVDFVNFLVTNDFSAIPEG 79 
217076311  73 YMKYTPLYEQHVKLGAKMVEFAGFQMPIQYTGIKDEVIAVRKDVGMFDVSHMGQVLVEGKDSTNFVNYLITNDFKNLSNG 152
150021749   1 -MKYTPLYEEHVKLGAKMVDFAGFNMPIQYTSIKDEVLAVRKNVGMFDVSHMGEVIVEGKDSTKFVDFLITNDFKNLKPG 79 
154249658  69 TVKYTPLYEDHVKLGAKIVEFAGYYMPLQYEGIIPEVHLVRKEVGMFDVSHMGEFICEGPDAVKFANYVVTNDFGSINYG 148
160903341  75 ELKKTPLYERHIELGAKLGEFAGWELPLWYSSIIDEHNAVRNCIGVFDVSHMGELFVQGKDAQKFVNYLITNNVEKIPIG 154
297566415   1 -MKTTPLTEIHQQLGAKMAPFAGYLMPIQYTSITAEHLAVRQGAGVFDVSHMGEFWVRGPQALDFLQYATLNDVSKLKVG 79 
14521302   81 SGIYTLVLNERGAIKDETLIFNMgNNEYLMICDSDAFEKLYAWFTYlkktIeqFTklDLEIELKTYdIAMFAVQGPKARD 160
46198456   80 RAQYSMLPNERGGVVDDIYLYRLgEEEYLMVVNAANIAKDLAHLQA----LakGF--RVELEDASErTALLALQGPKAQA 153
55980492   80 RAQYSMLPNERGGVVDDIYLYRLgEEEYLMVVNAANIAKDLAHLQA----LakGF--RVELEDASErTALLALQGPKAAS 153
157364810  80 QVMYTVMCNEMGGIIDDLLTYRFgEKQAMLVVNAANIEKDFDWIVN----QskQF--NVTVRNLSDqYGLIAVQGPLSER 153
222099448  80 KAMYTVMCNETGGIVDDLVVYRIsHEKAIMVVNAANIEKDYEWIKV----HakNF--NVEVRNVSDeTALVAFQGPKSQE 153
217076311 153 EIVYTAMCNENGGFIDDLLAYKIsDEKAFLVINAANIEKDFEWMKN----ValNF--DVKLENKSDdYALIAIQGPNAQK 226
150021749  80 EIVYTAMCNENGGFVDDLLAYKIsEEKAMLVINASNIEKDFSWMKK----IseSF--DVTLENKSDeYVLIAVQGPNAQK 153
154249658 149 DIIYTAMCNENGGFVDDLLVYKIaPEEVMFVVNAANIDKDFNHLLK----LseKF--NVKLTNISDeTGLIAVQGPKAQE 222
160903341 155 KIVYSPMCNEDGGILDDLLAYKLdEEKILLVVNASNTQKDFDWVRK----QssSF--NVEVINKSDeYCQIAFQGPKSQD 228
297566415  80 RAQYSMLPNERGGVVDDIYLYRTgEEEYLVVVNAANIEKDWSHLQR----LaeGF--SVRLEDASErTGLLAVQGPNAAK 153
14521302  161 LARDL-FGIDINEM----WWFQARWVELdgIK-------MLLSRSGYTGENGFEVYIedanpyhpdeskrgEPEKALH-V 227
46198456  154 LLQGL-VDVDLSTKrkndVFPARVAGRP-----------ARLARTGYTGEDGFELFL--------------APEDAEP-V 206
55980492  154 LLQGL-TDLDLSQKrkndVFPARVAGRP-----------ARLARTGYTGEDGFELFL--------------APEDAEP-V 206
157364810 154 FLKTF--VSDIDSL----SYYTFA-------SysvfgknCIVSRTGYTGEDGFEIYC--------------HWDDTFT-V 205
222099448 154 TLQRV-VDIDLEGI----GYYSFQWGRLdgER-------VLVSRTGYTGEDGFELMM--------------NAESAAK-I 206
217076311 227 TLQKL-TDIDLESI----GYYTFVFGKVkd-------veALISRTGYTGEDGFEIYT--------------TDKDGIVkI 280
150021749 154 TLQKI-TNVDLEQI----GYYTFTEGNVld-------ikAIISRTGYTGEDGFEIYT--------------TDKDGIIkI 207
154249658 223 KIQPH-VNFDLEEI----GYYSFKKGEIfg-------vrGIISRTGYTGEDGFELYI--------------PANQTSF-V 275
160903341 229 QLQKYlKDIDLDSI----EYYSFKILGLeg-------eeVILSRTGYTGEDGFELYL--------------SPAIAVK-V 282
297566415 154 VLQKL-CDVDLSSKkkndTFTATVag-----------kpARLARTGYTGEDGFELFT--------------EATDLRA-V 206
14521302  228 WERILE-EgkkyGIKPAGLGARDTLRLEAGYTLYGNETKElqllstdidEVTPLQANLEFAIYW-DKDFIGKDAL---LK 302
46198456  207 FLALVE-A----GAKPAGLGARDSLRLEAGFPLYGHELTE---------ETNPLCTPWAWVVKK-EKAFLGKEAM----- 266
55980492  207 FLALVE-A----GAKPAGLGARDSLRLEAGFPLYGHELTE---------ETNPLCTPWAWVVKK-EKAFLGKEAM----- 266
157364810 206 WNELLQ-RgnnfGVKPAGLGARDVCRLEASYMLYGNDMDE---------TTTPLEVGLSWVVKF-DKDFIGKDSL---IK 271
222099448 207 WDTLVEiAgn-vDGKPAGLGARDVCRLEASYLLYGQDMDE---------STNPFEVGLSWVVKM-NKDFVGKEALlklKE 275
217076311 281 WEELLN-L----GVKPAGLGARDTLRLEASLLLYGNDMDE---------TVTPLEAGIKWAVKF-DKEFVGKAAL---EK 342
150021749 208 WKKLLN-L----NVIPAGLGARDCLRLEASLLLYGNDMDE---------TITPLEVGIKWAVKF-EKDFMGKEAL---KR 269
154249658 276 WRKLLE-I----GVKPAGLGARDVLRLEAGLLLYGNDMDD---------TITPLEASIPWAVKFeKGDFFGKEVL---LK 338
160903341 283 WDRLIQ-LakevDGKPCGLGSRDTLRFEPKMLLYGNDMDE---------NTTPLEAGLSWTVDF-NKEFIGKEAL---LK 348
297566415 207 WDALLQ-A----GVTPCGLGARDTLRLEAGFPLYGHELTD---------ETNPRCTPFSWVVKE-HKEFYGKSAL----- 266
14521302  303 QKERGL-GRKLVHFKMVDKGIPREGYKV--YANgelIGEVTSGTLSPLLNVGIGIAFVKeeyaKP---GIE-IE-VEIRG 374
46198456  267 --LAQAcRERLVGLVL-EGGIPREGYRV--LSGgcpVGRVTSGGYSPLLQRGIALAYVE----EG---AEGpFQ-VEVRG 333
55980492  267 --LAQAcRERLVGLVL-EGGIPREGYRV--LSGgrpVGRVTSGGYSPLLQRGIALAYVE----EG---AEGpFQ-VEVRG 333
157364810 272 QKELGL-QKRIRGLEISDRRIARHGMYV--FKGekrVGVVTSGTFSPTLEKPVALAMLS----SEikiSDE-IE-VDIRG 342
222099448 276 KV-----ERKLVALELSGRRIARKGYTV--LKEgkeVGKITSGNFSPTLGKSIALALVS----RCvktGDR-LE-VVFPG 342
217076311 343 QLEEGL-KRRLKGFKLIDKGIARHGYKVfkDgr--eIGVVTSGTFSPTLDESIGMALIE----TGyksGDI-IE-IEIRN 413
150021749 270 QLEEGT-SRRLKGFKIIDKGIARHGYKV--FKDgkeIGYVTSGTFSPTLNQAIGMALIE----KGyksGEI-IE-IEIRN 340
154249658 339 QKEEGL-KRRLRGLVIEGKLVPRHNMEV--YKDgqkIGYVTSGTFSPTLEKPIAFVMID----ANvklNEK-VQ-IAIRD 409
160903341 349 QKEEGI-KRKLVGMEVHDKMPVRHGYEI--FKDnenIGFVTSGVKSPTLGKNLALGYVS----KEfskLETiVS-IKARE 420
297566415 267 --LAGGcDQVLVGLLL-EEGIPREGYRV--LVGgeeVGHITSGTFSPLIKKGIALAYVL----SG---AESgALqVEIRG 334
14521302  375 ARKKAITVTPPFYDPKKY 392
46198456  334 RAVPAALSPLPFVPLK-- 349
55980492  334 RAVPAALSPLPFVPLK-- 349
157364810 343 SKVKAMIVKLPFYRGSVK 360
222099448 343 KNVEAHVVKKPFYRGSVR 360
217076311 414 KLVKAEIVKMPFYRGSVR 431
150021749 341 KLVKAEIVKMPFYRGSVK 358
154249658 410 KMVDALVVKTPFYKGSVR 427
160903341 421 KLLEAEVVKTPFYKGSVK 438
297566415 335 KIYPAHLVNPPFVGLK-- 350
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