Conserved Protein Domain Family
MapZ_EC1
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pfam18041: MapZ_EC1 
MapZ extracellular domain 1
This is the extracellular domain 1 (MapZextra1) found in Streptococcus pneumoniae cell division site positioning protein MapZ. MapZ ensures accurate placement of the bacterial division site. The domain is a rigid four alpha-helices with two flexible linkers. The N-terminal end of MapZextra1 is connected to the trans-membrane segment of MapZ whilst the C-terminal is linked to MapZextra2 via a serine rich linker (SRL).The highly conserved residues are not accessible at the surface but are directly involved in many inter-helices interactions allowing for rigidity.
Links
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Statistics
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PSSM-Id: 465625
Aligned: 15 rows
Threshold Bit Score: 106.644
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q5M644   323 ASSAVISSSSKGASASDNKAFEDMYKNFFTDDEQTKLANDQF-GKLSDLEKLLKKLE-KTKYYDAAKTKYDNLKKQIEAI 400 Streptococcus therm...
EOT28195 223 KEKAEAARQEQLRVETAVARIESELDNFYLDQDEQFIVPGKTaADVEKLMKELEEYS-SEPKYKELRDKGQKLQVKIAVL 301
Q834V8   338 DQTQKAAAQEAAALTKKTDTLKDELAAFYTTKEQVFIKPDMVtVSPEKLSKQVAEIK-DSEEYSQLNKQIQTLKEKQQTI 416 Enterococcus faecalis
EOU17838 215 KEAEAQRIAAVKKENKEIDALEETIQEFYTDDKHVFVKADKVgQNTSKLAEEIAKHK-DSSRYDDLNTSYQRLLDKMNSI 293
BAK21596 307 QEENAQHHKTEKVQTSLIKQTNQLIDAYYTDTTHQFLKPDQVaVNTHKIQQNIEKLKsNHSSYKNLNRRLQELKDKQSIV 386
ESK61890 266 QRQDTNKSQVTQKADSQLSKLSVKVTQLFTTNKVEFLKATVTlAQIDDLSNQLEKYK-DDKGYTKLHQQLASAKQQWQKV 344
OJG23117 325 QRSNTSDEKVLEQVDQQVAKLSSKIDDLYTTKQRNFIKSTVTlAQINQLAKQLANFD-GQENYKKLKTRLEAAKEQLLAE 403
EOT84161 355 QELERQAQAELVKKEANVASLMKDIQALSVSKEEPIVKASTTkSQLTEYQKQLTALK-GIKEEKEASQFVDTLITQYTLQ 433
BAK60018 308 NNNEKAVNQAAVENKANLNAFNKAYDEFFTDADHQVLKNSNF-DQLSALKNKLKTLK-GSD-FDTAETKVNALETQIKAV 384
KXT77373 213 TTSSTSTTASSSQEQQLLEEFNKSYATFFTDSQQTKLKNSEF-SKLSSLQAILDKMDkNSEAYKTAKAKLDQLTSAIRAT 291

Q5M644   401 EKVNSKYESDALVDGSYNASISVKSDANFNDLservTNTGN-ASLDSIIQEVIKG 454 Streptococcus thermophilus LMG 18311
EOT28195 302 DQINSHFTEPIVVGDELKENVHVKDGDAVDMA----LLTDE-TPFSKLINEAIKK 351
Q834V8   417 QQINQLFEAPIVNGNEL-KPAILAADQPISVK----KLTGN-DPFDQLMNQAIDQ 465 Enterococcus faecalis
EOU17838 294 QKVNLLFTAPAINGDKLADNLQLKADQPVDVT----INTSD-QSFNELLNQAVTQ 343
BAK21596 387 TQVNQWFTQPIIKGNQL-AVATMAADKPMTIK-----KLDQkDAFSQLANQAIDQ 435
ESK61890 345 SEVNGYFTSPIIENGQLKEQATLDYSQKFAVKa---IANPQ-EPYEKLVNEAVAI 395
OJG23117 404 QDINGYFTKAILANGKLNHEAHIDYAKKFDLQ----LRKGK-TAFDQLANLAIKQ 453
EOT84161 434 EDLNKQFNTPVLVDGKVNDQAYVLNTQTFLAV----PIKDA-TAFDQAYNQAVTL 483
BAK60018 385 EKVNALFNKSAIVDGELNKEAQVKAAVSIPAV----PKTEN-EKLNKVLAQAINM 434
KXT77373 292 EKINQQFSGNLIVDGKLDTTVQVKSGADLSFS-----ASGL-TSVDNLLTSAVNF 340
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