Conserved Protein Domain Family
SanA

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COG2949: SanA 
Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin [Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 442192
Aligned: 192 rows
Threshold Bit Score: 110.64
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_128745264   1 MNS---------------TLRnn--rKF-WLTg---I------F-VLVVLTALPLIINQYMI-KTAGTAII--AEMKEDR 49 
AHX15100       1 MLH----------------------------------------A-AAVVLVALVLSLGLVWVgYLLHVWHVaaRSPLTLS 39 
WP_013559514   1 MYRr--------------TFS-----RI-VSM----F------I-VLILVATTLLLAARGFTaLYAKSRI---IPVADAP 46 
WP_015254637   1 MKAaeaqa------vrrrKRRsglpaRL-LKG----A------L-SAAVACAGWIAWIYWKIe----sF----EPKMELP 54 
WP_044277166   1 MKSg---------------VR-----LW-LS-----Lg-----M-GGLLVALTLPFVWRAGVeWAYASSI---YTLEEVP 45 
WP_047860922  11 MGRggk---------rarVLR-----RW-VLG----L------L-AMGLAAVLGVWVVSFYVeKRYADRI---IPRAEAP 61 
WP_083222250   1 MNLinrfhkt--spqsiiFHRqcdglRY-LYF----LrkesheLpTFLLITMIIGILPRIAIfMTTRRSIFs---dRQCP 70 
WP_095982756   1 MGSggh---------kkrWRR-----SA-LLM----V------L-GLGLGAALAVGAVSLYVeWRYVDRI---LPRAQAP 51 
WP_095041718   1 MDSlgrgcgftiisgvksLLR-----RGcLTg-----------F-IGIMLLAASPILWRSAVkVYYHRDM---YAPTEAP 60 
WP_087862560   1 MNY----------------LR-----RF-LLIvfhsI------L-YIFIGAFFLVGLIRTGIlIHSRPKT---FLPEDVP 48 
WP_128745264  50 EvsfvkeqqsafsglkAECILVLGAGLKPDgTPNHMLEDRLETAFALYKSGAAPKLLLSGDHGR--NEYDEVNAMKGYML 127
AHX15100      40 R---------------PMTVLVFGRRLVRd-QPETDYQLRLGRALALMRADMTDHVLLLGGRSG--GSVSEAAAGRAWLA 101
WP_013559514  47 E---------------MPVAIVFGAGLSRDgTPSPVLRDRVETAAALYFQGKVKKLLMSGDNRF--VDYNEPGAMRQYAL 109
WP_015254637  55 E---------------YDAGIVLGAALW-NgEPSPGLKERLDKAFELYREGRFRVFILTGGYDHagSRLTEAEGMKHYLA 118
WP_044277166  46 S---------------ARVALVLGARVYPDgRLSPMLADRVDTAIALYRAGKVEKLLMSGDNSH--ADYNEPGAMMAYAI 108
WP_047860922  62 Q---------------APVALVYGAGLAPGgVPSAVLAQRLDAAIALYRAGTVDSLLLSGDNSD--PFHDETRAMVRYVL 124
WP_083222250  71 P---------------NRFAVVLGAGIEKDgRPTRVLRERIETAVNLLRRANVSALVLTGGNKS--IYANETESMRLYAA 133
WP_095982756  52 Q---------------APVALVYGAGLAPGgKPSPVLAQRLDAALALYHSGTVGMLLLSGDNSD--RFHDETRAMVRYVR 114
WP_095041718  61 Q---------------HQVAVVFGAAVYGNgRLSPVLRDRVDTAIALYEAGQVERIIVSGDNSS--SYYDEPGSMMAYAI 123
WP_087862560  49 E---------------APVALVLGAGLNRDgSPGVVLRDRVETAAELYFSGKVEKLLMSGDNVS--QYYNEPGAMFDYAL 111
WP_128745264 128 ERGVPKEDIF-LDLAGFSTYDSMYRAKAVF---QVN--------SVIVVTQRYHQYRALYLAEKLGYKAYGVCSDQEV-- 193
AHX15100     102 DRELPPGIVLqLEQASIDSLENLRHARSLL---QEDgpvmqvlpPVALVSSRYHLARCQLLARRLGFDSVVVAAEPAFe- 177
WP_013559514 110 DLGVPAENIV-LDYAGRRTYDTCYRARAIF---GVT--------EAILVTQPFHLPRALYLCNQLGVKAWGVPADNRYyl 177
WP_015254637 119 ALGVPEDRLL-LEPEARSTYENLAFSRDVMdreRLR--------TALIVTHDFHAARARDVARWLGYEQPGFAAAESS-- 187
WP_044277166 109 RQGVPAEDIQ-PDYGGRRTYDSCYRARHIF---QVE--------EAIVVTQEFHLPRALFLCQNLGVAAVGVAADRRLyh 176
WP_047860922 125 DRGVPPQAVE-EDDAGLSTYDSSVRAHTVF---GVR--------EAVLVTQRFHLTRALYIANSVGIDAWGVAADEGRpr 192
WP_083222250 134 ELGVQNESIL-IDPDGFRSFDSCVNLLPL----RSN--------QITLVTQQFHLPRAVWIARRLGINAIGCVAPHHIer 200
WP_095982756 115 ERGVPSEAIQ-EDTAGLSTYDSSVRARTVF---GVR--------EALLVTQRFHLTRALYIANSVGIDAWGVAADEGRpt 182
WP_095041718 124 ERGVDPADIL-ADRAGHRTYDTCYRAGHVF---EIE--------SAILVTQAFHLPRALLTCAALGIDVVGVTADRRP-- 189
WP_087862560 112 SLGVPDEDIV-LDPAGIRTYDSCYRARDIF---GVN--------QLIIVTQAFHLPRALFICNALNIEAYGVSADDANyn 179
WP_128745264 194 YMGQTIRNIRE-ILARNKDFFKVMI-KPA---PSYLGD---IIPIS 231
AHX15100     178 LSRR--YLVRLlTESGYLMWIDIGvr-----wARLIGHqrmARRVS 216
WP_013559514 178 KRSQLIWNIRE-TMATLVALWEVWVtHPV---P-VLGP---YEPIF 215
WP_015254637 188 VLPASQRHVRE-IAAFTKWKLDSVLlRIGlqiPDRPGl-------- 224
WP_044277166 177 PRSIAWSEARE-TPATLAALLDIIr-RAP---PPVLGD---PIPLR 214
WP_047860922 193 ---tRRYALRE-TFSRVLALGMVLa-EAE---PRYPSG---RTLAS 227
WP_083222250 201 WDDFILWQLRE-FIACWRALIDVLRfQLH---SRKAN--------- 233
WP_095982756 183 ---tRRYALRE-TLSRVLALLMVWa-GAE---PQYPSG---APPPR 217
WP_095041718 190 YRDAGWYEIRE-TAATLVAAWDVMr-REP---PPLVEA---TPPLD 227
WP_087862560 180 RRGYIFWWARE-IPASSAAVWDVYFaRST---P-ILGQ---PEPIF 217
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