Conserved Protein Domain Family
TFP_LU_ECD_Bncr
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cd23597: TFP_LU_ECD_Bncr 
extracellular domain (ECD) found in Danio rerio protein Bouncer and similar proteins
Bouncer (bncr) is an oocyte-expressed fertilization factor that mediates sperm-egg binding and is essential for sperm entry into the egg. It is necessary and sufficient to mediate species-specific gamete recognition and fertilization, which is essential for vertebrate species performing external fertilization. Bouncer contains an extracellular domain (ECD), which belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).
Links
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Statistics
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PSSM-Id: 467126
Aligned: 20 rows
Threshold Bit Score: 99.2656
Created: 3-Mar-2021
Updated: 27-Apr-2023
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P0DPQ9        21 LRCLFCPVTSLns--sCAPVv-TECPVqELCYTADGRFGrssvLFRKGCMLRAdCSRSRHQMIrGNNISFSFSCCGGHYC 97  zebrafish
XP_016371843  34 LYCYYCPQTSFnr--sCRHVl-SECRPqELCFTARGRFGhapvLFSKGCMSQRdCVRSSSQMIrGNNISFTYSCCGRPYC 110 Sinocyclocheilu...
XP_018602791  23 LLCLYCPLQMKnk--fCRTVh-SMCPPeELCFRAKGYYAgdlgLTASGCMTKQqCTMKHLVSYkGTNFTMTYTCCNWNFC 99  Asian bonytongue
XP_015207687  37 LLCHFCPVHRLdv--aCVAMe-TECQPeELCYTGTGHRSglepLSAQGCLPRVlCGLQHPVSYrGSNYTMSSTCCSWDLC 113 spotted gar
XP_028841863  40 LLCFYCPLQPLns--tCTHSv-SECRPrEQCTRAEFVYGryaaFYSKGCAEQRdCGRERSARIrGADFTVTYACCQGDYC 116 denticle herring
XP_019712504  27 LRCLYRPILEKey--eFQPIv-TECPRgEVCYKAEGRYGnysaLSASGCMPRRvCGLQHDLSYqGVVYTMSYSCCDRPYC 103 tiger tail seah...
H2LID1        29 LHCYYSPVLEKe---iTFELvvTECPPnEMCFKGLGRYGnytaLSARGCMLEKdCSQVHSLRLlGTVYTMSYSCCDWPYC 105 Japanese medaka
XP_029008689  23 LLCFYRPLTEKe---kAFQPtlTECPPnELCFTADGRYGnhsaLSAQGCVAAGdCSRVLSTRFkGTAYATRYACCDWSYC 99  Siamese fightin...
XP_020790982  26 LHCYFSPYLTAeeqgtFKLVv-TECPPkEVCYKAQGRYGthngLVHRGCMLLEkCGQVKKISLrGAIYNTSYSCCDWSHC 104 great blue-spot...
XP_030221711  54 LRCFYSPLQDReqeaeSELVv-TACPHrEFCFKGVGHYGnrsaLTIRGCMENEsCYQVHVIRLkGTEYVLSFNCCPWPYC 132 Atlantic cod

P0DPQ9        98 N 98  zebrafish
XP_016371843 111 N 111 Sinocyclocheilus rhinocerous
XP_018602791 100 N 100 Asian bonytongue
XP_015207687 114 N 114 spotted gar
XP_028841863 117 N 117 denticle herring
XP_019712504 104 N 104 tiger tail seahorse
H2LID1       106 N 106 Japanese medaka
XP_029008689 100 N 100 Siamese fighting fish
XP_020790982 105 N 105 great blue-spotted mudskipper
XP_030221711 133 N 133 Atlantic cod
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