3HM5,1X58


Conserved Protein Domain Family
SANT_DMAP1_like
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cd11658: SANT_DMAP1_like 
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SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like
These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins.
Links
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Statistics
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PSSM-Id: 212556
Aligned: 8 rows
Threshold Bit Score: 73.5962
Created: 27-Feb-2012
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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putative DNAcalcium ion
Conserved site includes 11 residues -Click on image for an interactive view with Cn3D
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:by similarity to the DNA binding residues of yeast RAP1
  • Citation:PMID 8620531
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1     #                                 ## ## ### ### 
3HM5_A     33 WTKAETDHLFDLSRRFDLRFVVIHDRYDhqqfkKRSVEDLKERYYHIC 80  human
1X58_A     11 FTKEEVNYLFHGVKTMGNHWNSILWSFPfq--kGRRAVDLAHKYHRLI 56  house mouse
CAG11379   86 FSREEVAYLLKGVKTYGFSWNSILWSYPfk--pGRSNVSLAKKYRQLM 131 Tetraodon nigroviridis
Q1LX29    754 WSDKELCYLTKGVKRFGHSWNTILWKYPfh--pGRTNVDLAKKFYHMQ 799 zebrafish
1723640   164 WSFEEIEYLFNLCKKYDLRWFLIFDRYSyn--nSRTLEDLKEKFYYTC 209 baker's yeast
2275199   130 WTKEETDQLFEFCQNFDLRFVVIADRFPv----SRTVEELKDRYYSVN 173 thale cress
ABK24566  134 WTREETDQLFDLCEQFDLRFIIISDRFTp----SRSVEELKNRYYSAV 177 Sitka spruce
AAH02321  135 WTKAETDHLFDLSRRFDLRFVVIHDRYDhqqfkKRSVEDLKERYYHIC 182 house mouse

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