Conserved Protein Domain Family
DUF4270

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pfam14092: DUF4270 
Domain of unknown function (DUF4270)
This family of lipoproteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 444 and 534 amino acids in length.
Statistics
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PSSM-Id: 433711
Aligned: 61 rows
Threshold Bit Score: 153.728
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013306137            31 IGAEV-----IGGEPfT---TDKAvYD--VFAYNNKVe-----------AVRTN----KLPH-YQLGIF-NDPIYGKT-E 82  Marib...
WP_014937304            32 LGEQF-----FASGAaT---GETQsYD--VVAYNLNNn----------dTIQSDa--sRISQ-ATLGAF-AEDNFGMQ-K 86  Rieme...
jgi:Weevi_0980          31 vGDEL-----VGGG------ATGSkYEldLVAYNTTTdtil-----snqKVLQN---------AILGVY-NEPTFGQN-K 83 
WP_013633845            27 VGLDIdpdilLNSS---------------VDSSTTVLtkli-----kedSVVSN----YTER-SILGYM-NDNEFGKT-T 79  Pseud...
jgi:Phep_0132           27 IGLDLdpdyaIKGTLmDsa---------tVTSQTLKD------------EVASGv---GLVR-HPLGVM-VDPVFGKS-E 79 
PRJNA61269:NIASO_06775  32 LGQNV-----LPPIDnVh--TFDTtID--VTTTNGQF------------ALDADsfrtGLAFyQMIGKIsSDPLFGKT-D 89 
jgi:Sph21_3421          41 IGAEI------------------------VDSITVRTaty------qldPLPSN----GQGV-LLVGHM-NDEVMGNLtV 84 
CCH03492                59 VG--------VLYTDtLtitRTTAqFD----------------------SVRSN----DQST-LLVGRY-TDPVFGQV-Q 101
CCY35893                31 MGEGL-----IPGT--AtitVGTRtFDlpITNRTID-------------SVQSS----NSSN-MLIGTL-TDDTFGTM-- 82 
CDC98692                35 LGSNL-----VPDNQqMyagYVTI-----PRIDELNPkqyvetrlyqtdSIISS----NISY-GYFGQQ-LNDTIGRR-T 97 
WP_013306137            83 ARI-------TSQLLLP--TSR----PKFGVysqevednaenddsvstideneIATEVFLYI-PYL---------Rnlqs 139 Marib...
WP_014937304            87 SSY-------VTQLRLS--SYN----PDFGTn--------------------aKVDSVVLELkPIYa-------sDsatt 126 Rieme...
jgi:Weevi_0980          84 ARF-------YTQVRLS--GAN----PTFGQn--------------------pTVDSVVLRIpVYHkekaakqdtVkvts 130
WP_013633845            80 SNI-------VVALTLP--SSN----VSFGIn--------------------pILDSAVLVM-TYSn-------sAp--- 115 Pseud...
jgi:Phep_0132           80 AAV-------AMAVGLP--STG----YKFGTn--------------------aVIDSAVLVL-PYStq------------ 113
PRJNA61269:NIASO_06775  90 AQM-------YLQLSPT--AYPfknvPGk-----------------------lYLDSVVLVL-KHAg------------- 123
jgi:Sph21_3421          85 SSYfrignsaISNVTLPddAAF---------------------------------DSLSLAL-PYQg-------yY---- 119
CCH03492               102 AKSyaalqqsAAFVVYDsnTTN----PTPASr--------------------iILDSTRLIV-SLNgi------------ 144
CCY35893                83 -----------------------------------------------------MAHSASYIL-PYSds------------ 96 
CDC98692                98 AGF-------LSQMINYysVPE----GYFGEn--------------------pIFDSALLLL-SVEk-------yG---- 134
WP_013306137           140 dtdgdglideldsdpedstsdtdgdgvsdnqeklngtdplnedtdgdginddeddstikdnfakkidldsiYINNsvynk 219 Marib...
WP_014937304           127 stdedyiftgn----------------------------------------------vaakkvvttypiqkYGNN----- 155 Rieme...
jgi:Weevi_0980         131 gtdkdkiek--------------------------------------------------wwikntyeldsiYGHKd---- 156
WP_013633845           116 ----------------------------------------------------------------------lYGDSi---- 121 Pseud...
jgi:Phep_0132          114 ----------------------------------------------------------------------lYGDTi---- 119
PRJNA61269:NIASO_06775 124 ----------------------------------------------------------------------tYGDTt---- 129
jgi:Sph21_3421         120 -----------------------------------------------------------------------YGDTt---- 124
CCH03492               145 ----------------------------------------------------------------------wYGDTt---- 150
CCY35893                97 ---------------------------------------------------------------------tdFGDTrel-- 105
CDC98692               135 ------------------------------------------------------------------------VDTl---- 138
WP_013306137           220 dvtTSFNIKVERSty---fLrdld--pntnFQEAQEYYSTqqfspsfvsdllyegevivsneqilidqeddpnteevDES 294 Marib...
WP_014937304           156 ---KSLTLKVDEVnd---fL----------YSTEKKYYSNqkvalgvnlatvp-----------lngkvssvsitsdADS 208 Rieme...
jgi:Weevi_0980         157 ---ATMRLNVREMnt--------------vLFYDSLYYSNpnlrnkdqievlptvlg---steitktvvqnivkekdKST 216
WP_013633845           122 ----KYKVNINQLnet-----------lysSTKQKVYYTNkewnanttvvgske---------ffpaykdslniklyKYK 177 Pseud...
jgi:Phep_0132          120 --vPVYTVKVNQLtn--------------dISKETSYPTDkdwpaaatvlgtfsg-------kikpntklkiydivaGAA 176
PRJNA61269:NIASO_06775 130 ---IPQTLQVSEIdqs------------aqFRVDSSYLLSqtfptagvlgtatv----------ipahlkdsfqvvsYPN 184
jgi:Sph21_3421         125 ---LTQSFNLHRVte---eIelidesnaweEDEKPVFASGstlftnsafsyd--------------aiplgsvsfkhRPK 184
CCH03492               151 ---VPHELVVTRMtd--------------sLRRSQNYDIStvvpvgsqiiar--------------rtirprplsadT-- 197
CCY35893               106 -idAYLSLSIDST-----------------------YYLDpnqegihqririyk----------ltvpmdstlqfcnSIT 151
CDC98692               139 ---TTQHFAVYEIlsndylKe---------VEEDTTFYIGfd----------------------------------pVKA 172
WP_013306137           295 GVSKRLEP------------GIRVPL----D-I----------------DFFQANIIDREDG--------SEMV----SQ 329 Marib...
WP_014937304           209 KELLSRTV------------GVRIPL----D-A----------------QYFQDKIVNKQGA--------TELK----DA 243 Rieme...
jgi:Weevi_0980         217 TDFEEEV-------------AYKVML----D-K----------------DFFQQKIINNRST--------GNLS----DN 250
WP_013633845           178 DSTIKVVP------------QLRIPL----N-N----------------QFVIDNIIHLDS---------ATLS----TS 211 Pseud...
jgi:Phep_0132          177 DTLKTVVP------------QMRIKL----D-N----------------SFIQNNIINLDS---------VTLS----KQ 210
PRJNA61269:NIASO_06775 185 THT--TAN------------EIRIKL----D------------------NSFGQRLLAYDS---------AGASapyhND 219
jgi:Sph21_3421         185 TKTYSKSD------------TVFVKA----N------------------QSFGEDLWAKI----------KSGSsqvsNS 220
CCH03492               198 --------------------STIIPI----D------------------NSVGRELLALANSsastltstGTFI----DP 231
CCY35893               152 PDCYDPEPvtvsdpviygngSIRVDL----T------------------DSFASELLALEK---------EDFE----DL 196
CDC98692               173 GVYDPQKP------------LSRFTLggekEgEgpaatyvtltpteegkQYV-RHLMLQKAFdgddfpyeNDYSiysvDS 239
WP_013306137           330 ANF-NEFMRGIHLSTSs------ITDDVMLLLDMK------AANITIGY-NYDSIDLNETADDTSDdeivqkkgefifsm 395 Marib...
WP_014937304           244 ASF-IRYIKGIRLSVV-------ENDGYIFRFTPN------DTSIKMYY-TYDTTSNGTTTKTSAVy------------- 295 Rieme...
jgi:Weevi_0980         251 ATFiRNVLRGLEISVE-------NDNGFYFQFNPN------QIQLKMYY-SHDDTKVKEGEEPKrmqssydfg----frn 312
WP_013633845           212 QAF-ADHFKGLRLSIDkna-lgsQDGGAISFDTYTd----gASRLEIYY-RYTNSENKqdtts----------------- 267 Pseud...
jgi:Phep_0132          211 ANF-FKAFKGLHLTATt------TDKGGIVFFNLSg----tDGKIEVYYkRQNATTTTATDTVATSf------------- 266
PRJNA61269:NIASO_06775 220 STF-RTFFKGFAIKSTg------GGNGLMVVRPSGdasdssLTSLVVYY-KYDDPTTAGKIDTSFAs------------- 278
jgi:Sph21_3421         221 EEF-LEYIKGFVLVPT-------SKTSMVTAFATD------SILMKVYY-SYTRNTDGKKVQDSLN-------------- 271
CCH03492               232 NGFrQQVTRDFQFSLGg------TSPASVLGLSLS------STGILVYY-HVEGEKTAFREPQYFPf------------- 285
CCY35893               197 NKF-LEKIKGLYVMTEapi--gsASGGRLNYLNLG------TSTINLNY-RTDVTRNDGTVERIDTteafvfgy------ 260
CDC98692               240 VEQwVEQFRGLYIAPDpdqmiseYGKGTVFGTKLE------TSGLAIYG-RTRVKEDPSLIQDTVGmvyyf--------- 303
WP_013306137           396 lretqDGAIVGNAV-NTFENEIYPGAIDGVMDAEENAS---------RIYLKGGSGTYSKINLFsedeeea-qevinqIK 464 Marib...
WP_014937304           296 ----qFDLGSSNTHfNQIDYNRTSAYSTALANIDATNGd-------eRLYLQGMGGAGAVLRIPat----------eiQK 354 Rieme...
jgi:Weevi_0980         313 rwtslQSGPDFTVQlNQFSNQRSAELLSATQNPDRVNGa-------sRLYLNGMDGTMINLHIKpe----------alED 375
WP_013633845           268 -islpiAGSLGTAV-TEVKWDNAGTPALAALQSPANNQe--------KLYIKGLAGTKIKVDFP--------------NL 323 Pseud...
jgi:Phep_0132          267 ----pIGTATGPVT-ATIKHDYTGTPVKTQLDVPNPATpy------aITYLQALGGLRNKISFPylknf----vanakKP 331
PRJNA61269:NIASO_06775 279 -----ITLGANDAVaSNIQRDYSGSPAAAAFASATPAS---------LLYIQATPGSYANLKIP---------------- 328
jgi:Sph21_3421         272 -----MKVDDGSYQfNSIKVDRSQSLISALKADTEAELpgte--tkqQVMLQGLTGLVTKIQFPyly--------efvNR 336
CCH03492               286 ----------SGKRfNQITASRASTPLSTLRPGQSLTAtv-----tgRTYVQPGTGITTKLAFP---------------S 335
CCY35893               261 ----ttalnnfSTSsSHLESDTPGD----------------------ILYLEGLTGVKPHISARalkemidawiaeegLE 314
CDC98692               304 -yettSNNGFGNVSvNTVTHNYEEATTATKINIDDAREtnenrplhsRIHVEGLGGVISEMTFTreffetl-daeieaEN 381
WP_013306137           465 AEN------WIINEANLVFYIDQEALEMAGGIIep----pRLYLHNAEsk--------aPL---INTATENSNqetiklf 523 Marib...
WP_014937304           355 IKNlyknenIGILSAKIRLYTDDSVWNKSYAKP-------SNFLVKYA-----------NL---NDFLDDVSA------- 406 Rieme...
jgi:Weevi_0980         376 FRNkakgnnWIIVGAKVVMNVDNSYQDIASKp-------pYIFAWNHYqkeg---------kwiDEMYSDMTRqqsfvns 439
WP_013633845           324 SDLkklgsnIAINRAELIFTAEEPQQTSLKPLSq-----lRIYRWDLA-----------HQ---PALIPDENSsdpry-- 382 Pseud...
jgi:Phep_0132          332 ENGgnpntkIIINKAELVIDLNDGTdvfpfs----aaqrlSLYRLDIAsqranipdndnAI---------QGQyagdpra 398
PRJNA61269:NIASO_06775 329 --GlkgfpnCVVHLAELQMESVYDVSDSLFGApq----nmLVDVFDSTamafklmpyafPI--------TSQLqsdgkty 394
jgi:Sph21_3421         337 ND-------VIINKAELtietppns-------hipytpppSLNMMLAD-----------EHgvpKSLLTSSYEtttqvay 391
CCH03492               336 LKAllqsgrIAINRADLVVTPLAADDAKRPLpr-----flALSEIDGNnrlvrsdlstgAV---RLFTVQTQGpvsrspv 407
CCY35893               315 DEM------MVLSRAELRFPYEMPTDYERFDKEhp----aSIYAFTSTpwatdtlrfltPL---DDIYESSTSig----- 376
CDC98692               382 ERNnkdfrtLAFSQVTMSLYFNDSEYDWENIGSgsgnlsrLVEQMSAAperlgmytdykKLtpiADYYYTYEQqyetel- 460
WP_013306137           524 g-lfqnydgiINKSSD----------DKG--EKYTVRITDHINNLIIRdstsatlgltltpdiefigvsdamfdngeeEI 590 Marib...
WP_014937304           407 ----------MSLSSSyslvktsdltSNP--AYYDITITQTLKNIIEK------------------------------EA 444 Rieme...
jgi:Weevi_0980         440 yphnvhfnpmYNFKKNd--------------GQYIIDITDHLKSMIERgevfenqemrigmg---nflleigksniysEK 502
WP_013633845           383 -----lgtgfVGGIYN----------SPK--KIYVINVTGYIQDLFRN------------------------------KY 415 Pseud...
jgi:Phep_0132          399 lgsevlfggyFDSVR----------------KRYLFTVTSYIQDLMDGkted----------------------ygtfLA 440
PRJNA61269:NIASO_06775 395 yfsissssgfYSTNTTgqtyyykkdpSGNlvKQWRFNLTPYVQKYVNG------------------------------II 444
jgi:Sph21_3421         392 l------------------andlsggVGN--SKYTFNLTEYVSNYRGAmedkk--------------------sslylTI 431
CCH03492               408 yyaaaqvqqlDPRTNS-----------------YTFQVAGYLQSIVSG------------------------------VS 440
CCY35893               377 ---------dIDRAN----------------MVYSMNVTAYMQRLIMTpaedin------------------esmdlwIA 413
CDC98692               461 -----dyygkINRSRGc----------------YVMNITAYMQSLWNSyveerdaakaegr----eidmdnvknrtvyLG 515
WP_013306137           591 PVAAT--L----------------------TPLGTVLYGSEIDDpay-----------------idkKLKLEIFYTK 626 Maribact...
WP_014937304           445 ENKDLeiNvgdylkstqgtllgqkyntrayAPQRIVLVGSKTANq---------------------nKVKLNIIYAK 500 Riemerel...
jgi:Weevi_0980         503 PHYNNrvS----------------------SPHRLVFH----GNqssd----------------qekKLKLLVYYTQ 537
WP_013633845           416 PNDGTyiTtydfyg----------ktgrlnAPGRSVLFGGASNSvs--------------------qKVKLKIYYSd 462 Pseudope...
jgi:Phep_0132          441 PSSLTefNispsv------------tsaarSVINKFKYPRATGEk----------------------SLKLNIYYTQ 483
PRJNA61269:NIASO_06775 445 PLYSMrlYapaytrlpagdvnalsgtqpliFPAGTTTYTPAVGRvrlggg------------nhptqRMKLRLVYSK 509
jgi:Sph21_3421         432 PVSDL--L----------------------TKVDRLLIGKGDGNs----------------------PIKLRILYTK 462
CCH03492               441 PNNDLaiL----------------------TPSGSLFGQSQTTGalidqtqavlsdrvwrmvldgkaSVKLVLFYTK 495
CCY35893               414 PLREY--T----------------------DSYGTSYYDLDNGNynkiiln----------gpsaerHPTLTLTYGK 456
CDC98692               516 PEAYSlyT----------------------NSFGEVQGMPTSDSggtll-------------pennaPIRFTISYNM 557
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