7D27,2WTZ


Conserved Protein Domain Family
MurE

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COG0769: MurE 
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]
UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Statistics
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PSSM-Id: 440532
Aligned: 671 rows
Threshold Bit Score: 275.034
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7D27_A        24 GFSLDSRKVETGQIFIAL-TSYSQpeKTRT-FAEAALANGALAVISETElG-V-------ANE----WVCPDVRQRMGEW 89 
WP_041917483  19 NITSDPQKVgKDFLFYA--PS--E--KEHA-HIREAINRGARSILTNQKyEeEc------LAQgvnfFVHTQPQQIYHEV 85 
WP_012462281  17 NIAITAQSAKPNQIFFAL-PGISR--HGND-FIDIALANGASLIITDQA-P---------ITSysnvIVVKNITLVMKDI 82 
WP_125326525  25 GLTADSRAVRAGMLFAAL-PGTAT--HGAH-FIGTALEQGATAILTDAEgLrMaad--llADTdtaiVVAEDPRAALACA 98 
AIL12692      26 ALCVDSRQVQEKNLFLAI-PSFSE--NSTEpHILEAIQRGASIILMQQNtTlSprvleliETKkvaiFEIQNSRLMASAI 102
WP_085784961  21 GVSSDSRLTKTGELFIALkPLNGS--SNLP-YIKEAIEKGACAILKGLDeDlKdld--ssLLNkvkiIAVENPRFVRSRI 95 
WP_012179136  24 GLALDSRQVKEGYLFAGL-PGSRV--HGAE-FIQYALRMGAGAILTDAEgArIard--vlDGAevtlIVAEDPRQAFSAA 97 
WP_012673298  21 GVTCNPKKIKEGYLFVCV----SE--RDRI-YIDQILSCGAKAIIASDCiTeAlslgiipTRDagicIFHPNPQEIYSEI 93 
WP_083775302  52 GMSENSRAIKPGDMFAAV-AGSST--DGRI-YIKAAIDAGARVILTDMRpLeAp-----lDDLdtpiIMVENPRLVLAKA 122
WP_013300966  19 GLTADSRQVKPGFLFAAL-PGETT--DGRR-YIDQAIAAGAAAILAPTGt-----------TAtvpvLADDNPRQALAML 83 
7D27_A        90 QKRYLQQADvvKPLRIIAVTGTNGKTTISRLIAELISSQQQRCAVMGTTGNGIL----PNLT----------PSTHTTLD 155
WP_041917483  86 CSCMWK--K--QPAYMCAVTGTSGKRSVGHFFSQVCTLAGKKAVSLSASNEptDa--lG--Lw--------qEKDHMILD 149
WP_012462281  83 VNYLY--PK--FPKYLVAVTGTDGKTSVVNYFQQLCMLAGEQAASIGTLGVITT----NNHLnkllnqnkikPECATTMS 154
WP_125326525  99 AALWFG--S--QPETMVAVTGTNGKTSVATFTRQIWSALGHAAINIGTTGI-EG----AWSA----------PSSHTTPD 159
AIL12692     103 ASRLFS--A--HPSIVAGITGTNGKTSVASFTRQLWELLGAKSASLGTLGVQGTkvekSGLI----------DFSYSTPD 168
WP_085784961  96 AGKLYP--G--VPESLVAVTGTNGKSSVASFCRQIWTQLKHTACFMGTTGLDCP----ENLKel------lpEVKQTSVD 161
WP_012179136  98 AALWYG--A--QPATMVGVTGTNGKTSVASFTRQLWQGLGHAAANIGTTGI-EG----DFSA----------DLAHTTPD 158
WP_012673298  94 VSRFYQF-K--QPKYVAAVTGTNGKTSVVEFCRQIWQNSGYNAASIGTLGTCIN----NGRKg--------nSNSLTTPG 158
WP_083775302 123 AARFWH--K--QPGMIAAVTGTNGKTSTTDFLRQLWTRVTWQASSIGTLGVKGT----DTRKmdgk---ildLPKLTTPD 191
WP_013300966  84 AARFHA--G--QPKCIVGVTGTNGKTSVARFVAQLWSAFGHSAGTVGTLGASAP----GYDY----------ALRHTTPD 145
7D27_A       156 ALQLQNALHDYAKQGATFASLEASSHGLEQGRLNGCDIEIAVYSNLSRDHLDYHGTLEAYAEAKARLF-QFNS-LKVAVI 233
WP_041917483 150 AADMYSILDDLAGRRIEYCCLAISGAAIESRMIDSVNLKAAAFSNLLRDDLEQPEDIDKRFQMKVRLLsEVlPeDGIMVL 229
WP_012462281 155 YIQTRYVLHQLATNGINFVALEASSHGLDQNRLMDIKFQAAAFTSFSRDHLDYHKTMNKYLDAKLKLFkENIvsNGIAIV 234
WP_125326525 160 AITLQKLLAAAAEGGITHAAMEASSHGLDQRRLDGVRLKVAGFTNLTQDHLDYHGTMAAYLAAKARLFtRLLpeDGIAVV 239
AIL12692     169 PLILYPILENLKLQGVNHLAMEVSSHGLDMYRAEHVQFKVAAFTNLSHEHLDYHGTMEAYFQAKARLFkEVLssQGIAVV 248
WP_085784961 162 AFVLHQALSDMHRHGVTHVSMEASSHGLDQYRMDGIRFKSAGFTNIERDHLDYHQTMERYFSAKKRLFsDLIapNGVAVL 241
WP_012179136 159 PLTLHAALAEMAAQGITHAAMEASSHGLDQRRLDGVRLVAAGFTNFSQDHLDYHETFEAYFAAKAGLFsRVLadQGMAVI 238
WP_012673298 159 AEDLYATLRGIS---VEHLVLESSSHGIDQYRIHGLKLSAAAFTNFSQDHLDYHKSLGGYLETKKRLFyEVLpeGKTAIL 235
WP_083775302 192 SVSLHSALSPLCDAGVTHLALEASSHGLVQQRLDGLNIHIAAFTNLTQDHLDHHNDMESYFIAKSHLFmDLLmhAGAAII 271
WP_013300966 146 PVELHQVISTMAAMGTTHLAMEVSSHGLAQHRADGVRFSHAGFTNITQDHLDYHPSFEAYFAAKMRLLtALLpeTGQAVI 225
7D27_A       234 NLDDAHADLMIKSAQNnpa--qpkILTYSLtQNTADYYI-ADLDYSLAGATFNLVsq-qGSFaVESPLLGHFNVENLIAA 309
WP_041917483 230 PVASEYTTRIIQHCPNk------kVCTYG--RATSDIQLiSQLP-TQKGQILTMKvl-gKEMvIHTNILGKFHGNNLVTA 299
WP_012462281 235 NNNINELSiIQSKITDef-----gLkLLSV-EQQGDIQI-IDVQSSLNGQKVHFRyk-nSDYkFEVPVIGRVHITNILIA 306
WP_125326525 240 NLDGAKGSDMAELALArg----lrVLTVGK-GQGADLQI-AATRPDATGQEVRYLwq-gRAFqTRLALIGAFQAENVAVA 312
AIL12692     249 NVGTNFGQEIAKICAQrg----lnLVTLGH-E-NSDIHV-QKIVTELQGNQIFFKaf-gKAYsVFLPLVGQFQVENVLTA 320
WP_085784961 242 NADVKEFKPLQELCRHhd----vrYMSYGW-QGQ-ELRL-LKIKPHANGQTIDLEaf-gKTHqINLPLIAEFQAMNALCA 313
WP_012179136 239 NLDDPKGADMMAIAHGag----aeLLTVGT-HKDAMLRL-TAQRFDADGQEMRFTwk-gVAHqARLNLVGGFQASNVLVA 311
WP_012673298 236 NADIDEYGALLKIAEKrs----nkVVTYGK-KGS-DITL-LEQTSTPNGQHLTVKid-nQIYnTFFPVLGKFQAYNLLCA 307
WP_083775302 272 NIDDPYGRRLCDMLTAqgdarqivIQTFGF-ADDADFQI-EKITPIDNILDMSVKhd-gKSWhIPLAMSGTFQAVNALTA 348
WP_013300966 226 TTDGAGAEGAIEAAQGag----rrVLTVGR-RGE-TLKL-LSCVPHQGGLALTVSveegPAQsVALSLIGDFQADNALVA 298
7D27_A       310 LIAAEQAGFDLQALVDFVPKLIGAPGRMQVI-R-D---DERLFVVDYAHTPDALIQVLKTLK-RH-V-SNQLWAVFGCGG 381
WP_041917483 300 MGLAISCGIDPSSIEHE--QISPLAGYMEFLeEyG---EERKIMTDCAQTPSELHDLLLSIKwHF-P-YNDVTLVLRCSE 372
WP_012462281 307 LLLAINIGLDSAKLIPLLSNLKPIKGRMEKIqF-G----NCYAFVDYALTPNALATMLTELR-ALnN-KGRLITIFGGSE 379
WP_125326525 313 AGLAIAAGDAPEAVLATLPRLTGVRGRMQLAaTrR---NGAAVYVDYAHTPDAVETALRALR-PH-V-MGRIIIVFGAGG 386
AIL12692     321 FAIAISTGAHCEEAIKVLENLQGVKGRMEFVgEsK---AGASIFIDYAHKPLALETVLKSLR-AH-T-HGQIFVVFGCGG 394
WP_085784961 314 TGLVVGAGDSIEDVLPCLEKLKTVSGRMQKAgEtP---KKGIVYIDYAQNIDGMRTALKTIR-PY-T-KRNLTVIFGCGG 387
WP_012179136 312 MGLVMATGAQVGDLVPLLPRLATVRGRMQKVaRrE---NGATVFVDYAHTPDALKTALRALR-PH-V-LGRLVVVFGAGG 385
WP_012673298 308 IGI---SGLNYREI--CVEKLVSPPGRMEKVkP--------FAFVDYAHTPSALKQALLSLK-WH-I-NKKIILVFGCGG 371
WP_083775302 349 GIMAYMSGLPLQDSLGGLAYLKPAPGRMQTVtGhP---QGAQIVVDFAHTPDALRAALEALR-PE-V-SHKLYVLFGCGG 422
WP_013300966 299 AGLVIASGAEPEAVIEAMAKLSAAPGRMQPAgQkScegGMASAFVDYAHTPDAIATALRAIK-PH-VpGGRVVVVIGAGG 376
7D27_A       382 DRDR-GKRPLMTQAALDGANPVILTSDNPRTEDPEQIFADMKQGIDfSGHrMHEIHDRREAIKFVAE-QAQAGDIVVIAG 459
WP_041917483 373 NYEG-KNTLKMAKIAAKMVNRIIFTSDSNGSTLTEKSRRELMSCCP-KA--IE-IEDRKKAMEYAIN-NCKPSEIIVMQG 446
WP_012462281 380 NRDAiARRVQMGIVASKLSDLVIVTDQDSGNEDPAAIRKEILQVAR-S---AIEIPNRGEAIKYAIS-IMVDNDILLIAG 454
WP_125326525 387 DRDR-SKRPLMGEAARKHADVLYVTDDNPRTEDPAAIRAAVMAACP-EA---NEVGDRAEAILRAVD-ALLPGDALLIAG 460
AIL12692     395 DRDQ-AKRPMMGKIATNHANCVIITDDNPRSEDPQAIRRQILEGAP-HAY---EIASREEAIAYAIQ-KAKAGDICLIAG 468
WP_085784961 388 GRDL-SRREGMGIAAREGADRVIITDDNPRYEDPQLIRTSLLKGCP-DA---IEIPNRSEAIRHALS-TLEEGDICLIAG 461
WP_012179136 386 DRDS-GKRPLMGAAAAAAADVVFVTDDNPRSEDPALIRAQVRAGCP-EA---TDVPDRAEAILRGVD-ALEPGDVLLIAG 459
WP_012673298 372 NRDQ-TKRSEMGKIAQMYADKVIITDDNSRDEDPAKIRHDILLHCP-DA---LEIGGRREAIEKGVDiAYNEGMILLVAG 446
WP_083775302 423 DRDP-SKRALMGAIADDAADVVIVTDDNPRSEDPASIRSAIMAASP-KS---IEIFPRDTAIKTALE-QLVEGDVLLIAG 496
WP_013300966 377 DRDR-TKRPLMGRAAAAGADLVIVTDDNPRSEDPAAIRSQVAEGAP-GA---QIIGGREAAIRAGAE-ALKAGDVLLVTG 450
7D27_A       460 -K-GHENYQ-EINGVRHWFDDV-VEVRSAI-DA 487
WP_041917483 447 vKsSIDK-RgVV-N------DaaaMLKAVVaPQ 471
WP_012462281 455 -K-GHETRQ-VLKGRIINYNDM-EQVKLYL-KQ 482
WP_125326525 461 -K-GHESGQ-IIGTDVYPFDDV-EQASVAV-AA 488
AIL12692     469 -K-GHEQGQ-IIGSVNYPFCDR-SVAQNIL-AK 496
WP_085784961 462 -K-GHEREE-IVGDQRIPYNDF-EEAQKIL-LA 489
WP_012179136 460 -K-GHETGQ-TVGDVVYPFDDA-EQASVAV-AA 487
WP_012673298 447 -K-GNEKFQ-IIGNQTFEFSDV-EVIKNHA-LT 474
WP_083775302 497 -K-GHETVQ-LIGDETLPFSDI-SVASRII-AD 524
WP_013300966 451 -K-GHEQTQ-TIGHVTYPFDDV-STTLAAM-GG 478
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