Conserved Protein Domain Family
Lys_export

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pfam03956: Lys_export 
Lysine exporter LysO
Members of this family contain a conserved core of four predicted transmembrane segments. Some members have an additional pair of N-terminal transmembrane helices. This family includes lysine exporter LysO (YbjE) from E. coli.
Statistics
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PSSM-Id: 427613
Aligned: 167 rows
Threshold Bit Score: 105.58
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CDC99986            8 LCCFLLGIAVGLsgLSPE----WLLDAALPSLLLSLLILQV---GVGLGAN-DDLRGI---VRSLRLRMLLLPLFTIAGS 76 
Q97WN6            111 MLPFISGWIFGLlfHIND-----NIVINLVDYELYALASVL---GYTMGKDvNRKV-----ILNSSKDSLISLFITILGD 177 Saccharolo...
Q96XQ5            109 ILPLILGLLLGFfiKVKI------NFNEIIDYELYALVIVI---GIQVGESlK--LEI---LKRISGLAIVSILVDVFGA 174 Sulfurisph...
Q4JC27             99 LIPLVLGFVVGLllRVNI------PFGNIIDYELYILALVI---GIDVGSAiS--LKT---LMKMSKVAIFAVIIDVISA 164 Sulfolobus...
RogerUC:Ahos_1531  98 LLPLIIGFLVGLitRFYSiiisDSVFDEVIDWELYVLAVVI---GISIGKElK--KEL---MKRISRFAIFSVIIAIIGG 169
jgi:Msed_0718      92 gvPLVLGLSLGFlvKPSL------DYSEIIVYELYILALVI---GFNIGSEiK--FRA---ILHVTREALVTTLVVIIGA 157
WP_012186879      104 IITLVIGWLTGLllHVTG-------IGNIIEAELIALAGVI---GLSSSRVmN--VKS---LMAGGRIGMQAGVSALLGG 168 Caldivirga...
Q9YBX3            118 LAFFLAGLASGWlt-------gSSFPDVVSTLLLYILLFQA---GYLVGGA-----AGlrgMLRGGRLGLLLALSCLVGG 182 Aeropyrum ...
WP_015233171       12 lGVFTSGLLLGIfvKFPI-----YDVETIAVYWLYILLGII---GIVIGVSfRDLLRT---AIKGIRNGILLTLSVIIGD 80  Caldisphae...
WP_013266687       12 aSAFVIGIALGAalRP--------RPDDVLPYAYIFLYIVVataGAYVGLSwRRLASA---GRRILSVGLMFTAAALVGD 80  Acidilobus...
CDC99986           77 LLFSAAAALLPgNR-PLAECLAVGSGFGYYSLSSVLI-ADVGaaslgeggAAELATVALLANVVREMFALFCLSLFARW- 153
Q97WN6            178 IILALVIYML--HIaNLTISFAIALASGWYSYVGPLV-AVSS--------NPYLGTLAFLINFLREQLTYVLVPFLLRVk 246 Saccharolo...
Q96XQ5            175 IISAILLSPFY----PFKEILLTTLGSGWYSYTGPFL-AKYY--------GPTIGVFAFLVNFLREQLTFLLIPLFFRVr 241 Sulfurisph...
Q4JC27            165 VLVALIISPVI----NLKEGLMIMLGSGWYSYTGPFV-ARYY--------GPVAGIIGFLVNFLREQLAFVLVPIFLKFr 231 Sulfolobus...
RogerUC:Ahos_1531 170 IISSAILFLFL-SIrPFNLALAISLGSGWYSYTGPIV-AKYY--------GPIYGVIAFLVNFLREQFTFSLLPIFLRIr 239
jgi:Msed_0718     158 VVCALASFGLG-LLpNLKLALVMFLGAGWYSYTGPIV-STYY--------GPVYGVIAFLTNFFREQLAFLVVPVLVKAr 227
WP_012186879      169 LASGLILSYVF-NI-RLNVSLAIALGMGWYTFTGPMV-ALYA--------GPYYGLLAFLSNFLREQLTFILVPFI---- 233 Caldivirga...
Q9YBX3            183 VIGGAAAAFVL-GW-SLEAGVAMGVSSGWYSLAGPLLyTI----------DPYYGAVALVGNMLREAFHIVVYPLLARR- 249 Aeropyrum ...
WP_015233171       81 IIAGFLISLIL-RQ-GLNYSLSISLGSGWYSLIGPFV--SFY--------NPYFGVIGFVSNLLREAYTLSLFPLIYSF- 147 Caldisphae...
WP_013266687       81 AAAGLAIAELL-GL-PLRLTVAAALGSGWYSFTGPFL--SLF--------SPSMGVIGFVANQLREDLTLALFPAI--Dr 146 Acidilobus...
CDC99986          154 CGRV-APISAAGINSMDVCLPGIVRYSggSTQLVPLAVLHGIALEVSVPLLIGFFC 208
Q97WN6            247 FEPR-SAVAVGGATAMDTTLPLYVEVL--GKEYALSAMITGVILTLIIPIILPLIi 299 Saccharolobus solfataricus
Q96XQ5            242 ASPI-GAIAVGGATSMDVTLPLYVDLL--GNEYAIGALINGLILTLLVPILLPLVe 294 Sulfurisphaera tokodaii
Q4JC27            232 PTPV-GAIAVGGATSMDVTLPLYVEVL--GNEYMIGAMVSGVILTIAVPIILPLVS 284 Sulfolobus acidocaldarius
RogerUC:Ahos_1531 240 STPL-GAVAVGGATSMDTTLGFYVDVL--GYEYGVGAMINGVVLTLIVPLILPIIL 292
jgi:Msed_0718     228 PNPY-SAIAIGGATSMDTTLGLYSSIF--TGEYSVSAMMSGALLTLIIPVMLPLVL 280
WP_012186879      234 PGSPqALISIGGATSMDDTLPVYVSVL--GNEYSVASISNGLLLTILVPIIVPLVL 287 Caldivirga maquilingensis
Q9YBX3            250 IPI--QAVAFGGATTMDTGLPVILASS--GERAALPAFVQGALLTLLLSLLLPLYV 301 Aeropyrum pernix
WP_015233171      148 FGT--PSIAMGGATTMDTTLGVIIKYS--GIENSSSAILQGLIITIILPFILPFTi 199 Caldisphaera lagunensis
WP_013266687      147 LIGE-GSVVMGGATSMDTTLGVITRYA--GPETGLEGLVQGVVLTLLIPIIVPAVV 199 Acidilobus saccharovorans
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